More than 300 homologs were found in PanDaTox collection
for query gene Slin_2944 on replicon NC_013730
Organism: Spirosoma linguale DSM 74



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013730  Slin_2944  two component transcriptional regulator, winged helix family  100 
 
 
223 aa  452  1.0000000000000001e-126  Spirosoma linguale DSM 74  Bacteria  normal  0.470859  normal  0.70587 
 
 
-
 
NC_013730  Slin_2619  two component transcriptional regulator, winged helix family  63.68 
 
 
224 aa  298  3e-80  Spirosoma linguale DSM 74  Bacteria  normal  0.189992  normal 
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  60.54 
 
 
223 aa  293  1e-78  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  57.33 
 
 
230 aa  275  3e-73  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_013037  Dfer_2762  two component transcriptional regulator, winged helix family  54.22 
 
 
225 aa  267  8.999999999999999e-71  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0732  two component transcriptional regulator, winged helix family  55.8 
 
 
231 aa  253  1.0000000000000001e-66  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013132  Cpin_3739  two component transcriptional regulator, winged helix family  51.77 
 
 
266 aa  248  4e-65  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.453489  normal  0.0202921 
 
 
-
 
NC_013730  Slin_4793  two component transcriptional regulator, winged helix family  50.88 
 
 
225 aa  244  6e-64  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_0453  two component transcriptional regulator, winged helix family  54.71 
 
 
225 aa  241  5e-63  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.904663  normal 
 
 
-
 
NC_013037  Dfer_2743  two component transcriptional regulator, winged helix family  48.23 
 
 
228 aa  240  2e-62  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_2552  two component transcriptional regulator, winged helix family  46.05 
 
 
230 aa  229  2e-59  Spirosoma linguale DSM 74  Bacteria  hitchhiker  0.0000276879  normal  0.180215 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  48.43 
 
 
225 aa  229  3e-59  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_1849  two component transcriptional regulator, winged helix family  46.46 
 
 
228 aa  226  2e-58  Spirosoma linguale DSM 74  Bacteria  normal  0.418833  normal 
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  47.98 
 
 
223 aa  224  1e-57  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  49.1 
 
 
240 aa  223  1e-57  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_013061  Phep_3673  response regulator receiver  49.11 
 
 
227 aa  223  2e-57  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  50.22 
 
 
227 aa  223  2e-57  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_013132  Cpin_1247  two component transcriptional regulator, winged helix family  46.58 
 
 
235 aa  221  7e-57  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.464606  normal 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  49.33 
 
 
224 aa  220  9.999999999999999e-57  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  47.32 
 
 
236 aa  219  1.9999999999999999e-56  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  47.3 
 
 
223 aa  218  5e-56  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_013037  Dfer_0274  two component transcriptional regulator, winged helix family  45.81 
 
 
232 aa  218  7e-56  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.701823  normal  0.83989 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  47.98 
 
 
224 aa  217  1e-55  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_013037  Dfer_0577  two component transcriptional regulator, winged helix family  46.9 
 
 
231 aa  217  1e-55  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.0903513 
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  46.85 
 
 
225 aa  216  2e-55  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  45.5 
 
 
223 aa  215  4e-55  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  45.74 
 
 
225 aa  214  5.9999999999999996e-55  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_007517  Gmet_1026  two component transcriptional regulator  44.84 
 
 
224 aa  214  7e-55  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.000442073 
 
 
-
 
NC_009441  Fjoh_3400  two component transcriptional regulator  47.09 
 
 
224 aa  214  7e-55  Flavobacterium johnsoniae UW101  Bacteria  normal  0.105495  n/a   
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  45.5 
 
 
223 aa  214  7e-55  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  47.98 
 
 
224 aa  214  7e-55  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  49.1 
 
 
223 aa  214  8e-55  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_008699  Noca_1613  response regulator receiver  46.64 
 
 
225 aa  214  8e-55  Nocardioides sp. JS614  Bacteria  normal  0.97266  n/a   
 
 
-
 
NC_013061  Phep_1345  response regulator receiver  45.58 
 
 
227 aa  214  9e-55  Pedobacter heparinus DSM 2366  Bacteria  normal  normal  0.71904 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  48.2 
 
 
230 aa  213  1.9999999999999998e-54  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_3423  response regulator receiver protein  46.19 
 
 
224 aa  213  1.9999999999999998e-54  Streptosporangium roseum DSM 43021  Bacteria  normal  0.699539  normal  0.107362 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  47.51 
 
 
225 aa  212  3.9999999999999995e-54  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  47.53 
 
 
224 aa  212  3.9999999999999995e-54  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  47.98 
 
 
224 aa  212  3.9999999999999995e-54  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  46.82 
 
 
225 aa  211  5.999999999999999e-54  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  45.05 
 
 
223 aa  211  7.999999999999999e-54  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  46.36 
 
 
225 aa  211  9e-54  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  45.95 
 
 
223 aa  211  1e-53  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_002947  PP_0047  DNA-binding heavy metal response regulator, putative  47.75 
 
 
224 aa  209  2e-53  Pseudomonas putida KT2440  Bacteria  normal  0.116112  hitchhiker  0.00000494979 
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  45.91 
 
 
225 aa  209  2e-53  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_0064  two component heavy metal response transcriptional regulator  47.75 
 
 
224 aa  209  2e-53  Pseudomonas putida W619  Bacteria  normal  hitchhiker  0.000118539 
 
 
-
 
NC_010322  PputGB1_0061  two component heavy metal response transcriptional regulator  47.75 
 
 
224 aa  209  2e-53  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0868462 
 
 
-
 
NC_009512  Pput_0061  two component heavy metal response transcriptional regulator  47.75 
 
 
224 aa  209  2e-53  Pseudomonas putida F1  Bacteria  normal  0.382659  hitchhiker  0.0034413 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  45.91 
 
 
225 aa  209  3e-53  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  44.59 
 
 
223 aa  209  3e-53  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  44.59 
 
 
223 aa  209  3e-53  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_2007  two component transcriptional regulator  48.87 
 
 
223 aa  209  3e-53  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  47.09 
 
 
228 aa  209  3e-53  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  47.73 
 
 
224 aa  208  6e-53  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  47.73 
 
 
219 aa  207  8e-53  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010070  Bmul_6295  two component heavy metal response transcriptional regulator  43.69 
 
 
223 aa  207  8e-53  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.803537  normal  0.219108 
 
 
-
 
NC_014212  Mesil_2637  two component transcriptional regulator, winged helix family  47.96 
 
 
227 aa  207  8e-53  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  47.27 
 
 
226 aa  207  9e-53  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  47.75 
 
 
228 aa  207  9e-53  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  44.59 
 
 
224 aa  207  1e-52  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  45.98 
 
 
228 aa  207  1e-52  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_004578  PSPTO_1307  DNA-binding heavy metal response regulator  45.91 
 
 
225 aa  207  1e-52  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.150056  n/a   
 
 
-
 
NC_008025  Dgeo_2318  two component transcriptional regulator  45.7 
 
 
225 aa  207  1e-52  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.642935  normal 
 
 
-
 
NC_013124  Afer_0703  two component transcriptional regulator, winged helix family  46.19 
 
 
236 aa  207  1e-52  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  46.88 
 
 
226 aa  207  1e-52  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  47.3 
 
 
228 aa  206  2e-52  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_007005  Psyr_1127  heavy metal response regulator  45.91 
 
 
225 aa  206  2e-52  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.294376  normal  0.216529 
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  48.18 
 
 
231 aa  206  2e-52  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  45.74 
 
 
226 aa  206  2e-52  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_011662  Tmz1t_2101  two component heavy metal response transcriptional regulator, winged helix family  48.02 
 
 
228 aa  206  2e-52  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_3411  two component transcriptional regulator, winged helix family  46.82 
 
 
224 aa  206  2e-52  Cyanothece sp. PCC 7425  Bacteria  normal  0.591115  normal 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  44.59 
 
 
224 aa  206  2e-52  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011667  Tmz1t_2388  heavy metal response regulator  48.02 
 
 
228 aa  206  2e-52  Thauera sp. MZ1T  Bacteria  decreased coverage  0.000142984  normal  0.119734 
 
 
-
 
NC_013165  Shel_13760  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  43.95 
 
 
225 aa  206  3e-52  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_007413  Ava_0615  two component transcriptional regulator  45 
 
 
228 aa  206  3e-52  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0841359  normal  0.719107 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  45.45 
 
 
225 aa  206  3e-52  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  45 
 
 
224 aa  205  3e-52  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  45 
 
 
225 aa  205  3e-52  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  46.4 
 
 
227 aa  205  4e-52  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  44.09 
 
 
223 aa  205  4e-52  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_010468  EcolC_3412  two component heavy metal response transcriptional regulator  45.66 
 
 
226 aa  205  4e-52  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_013525  Tter_1435  two component transcriptional regulator, winged helix family  44.34 
 
 
233 aa  205  5e-52  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_008752  Aave_3002  two component transcriptional regulator  49.32 
 
 
230 aa  204  6e-52  Acidovorax citrulli AAC00-1  Bacteria  normal  0.67465  normal  0.369251 
 
 
-
 
NC_013946  Mrub_1103  two component transcriptional regulator, winged helix family  46.15 
 
 
227 aa  205  6e-52  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  44.84 
 
 
225 aa  204  7e-52  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  47.27 
 
 
226 aa  204  7e-52  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_1438  DNA-binding response regulator CzrR  46.61 
 
 
224 aa  204  8e-52  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_4283  two component heavy metal response transcriptional regulator  46.61 
 
 
224 aa  204  8e-52  Pseudomonas putida F1  Bacteria  normal  0.0230752  normal 
 
 
-
 
CP001637  EcDH1_3058  two component heavy metal response transcriptional regulator, winged helix family  45.25 
 
 
227 aa  204  1e-51  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  43.89 
 
 
224 aa  203  1e-51  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_010468  EcolC_3075  DNA-binding transcriptional activator CusR  45.25 
 
 
227 aa  204  1e-51  Escherichia coli ATCC 8739  Bacteria  normal  0.204173  normal 
 
 
-
 
NC_009800  EcHS_A0618  DNA-binding transcriptional activator CusR  45.25 
 
 
227 aa  204  1e-51  Escherichia coli HS  Bacteria  hitchhiker  0.000374882  n/a   
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  44.8 
 
 
228 aa  204  1e-51  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_007511  Bcep18194_B2768  two component heavy metal response transcriptional regulator  44.59 
 
 
223 aa  204  1e-51  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  44.8 
 
 
228 aa  204  1e-51  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  44.09 
 
 
224 aa  204  1e-51  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_010498  EcSMS35_0588  DNA-binding transcriptional activator CusR  45.25 
 
 
227 aa  204  1e-51  Escherichia coli SMS-3-5  Bacteria  normal  0.372008  normal 
 
 
-
 
NC_009801  EcE24377A_0589  DNA-binding transcriptional activator CusR  45.25 
 
 
227 aa  204  1e-51  Escherichia coli E24377A  Bacteria  normal  0.180273  n/a   
 
 
-
 
NC_011353  ECH74115_0651  DNA-binding transcriptional activator CusR  45.25 
 
 
227 aa  204  1e-51  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.589216  normal 
 
 
-
 
NC_012892  B21_00521  hypothetical protein  45.25 
 
 
227 aa  204  1e-51  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
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