More than 300 homologs were found in PanDaTox collection
for query gene Slin_4793 on replicon NC_013730
Organism: Spirosoma linguale DSM 74



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013730  Slin_4793  two component transcriptional regulator, winged helix family  100 
 
 
225 aa  461  1e-129  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_0453  two component transcriptional regulator, winged helix family  67.11 
 
 
225 aa  300  1e-80  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.904663  normal 
 
 
-
 
NC_013037  Dfer_2762  two component transcriptional regulator, winged helix family  55.56 
 
 
225 aa  267  1e-70  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  53.78 
 
 
230 aa  266  2.9999999999999995e-70  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_013132  Cpin_3739  two component transcriptional regulator, winged helix family  53.98 
 
 
266 aa  246  1e-64  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.453489  normal  0.0202921 
 
 
-
 
NC_013730  Slin_2619  two component transcriptional regulator, winged helix family  51.12 
 
 
224 aa  244  9.999999999999999e-64  Spirosoma linguale DSM 74  Bacteria  normal  0.189992  normal 
 
 
-
 
NC_013037  Dfer_2743  two component transcriptional regulator, winged helix family  51.33 
 
 
228 aa  238  4e-62  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_0274  two component transcriptional regulator, winged helix family  51.77 
 
 
232 aa  236  2e-61  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.701823  normal  0.83989 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  52.68 
 
 
226 aa  234  7e-61  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  53.15 
 
 
228 aa  233  2.0000000000000002e-60  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0732  two component transcriptional regulator, winged helix family  52.47 
 
 
231 aa  231  8.000000000000001e-60  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_1849  two component transcriptional regulator, winged helix family  49.12 
 
 
228 aa  229  3e-59  Spirosoma linguale DSM 74  Bacteria  normal  0.418833  normal 
 
 
-
 
NC_013061  Phep_1345  response regulator receiver  50.22 
 
 
227 aa  227  9e-59  Pedobacter heparinus DSM 2366  Bacteria  normal  normal  0.71904 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  49.78 
 
 
224 aa  227  1e-58  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  52.25 
 
 
225 aa  227  1e-58  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_009441  Fjoh_3400  two component transcriptional regulator  49.78 
 
 
224 aa  226  2e-58  Flavobacterium johnsoniae UW101  Bacteria  normal  0.105495  n/a   
 
 
-
 
NC_013730  Slin_2944  two component transcriptional regulator, winged helix family  50.88 
 
 
223 aa  226  2e-58  Spirosoma linguale DSM 74  Bacteria  normal  0.470859  normal  0.70587 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  49.11 
 
 
223 aa  226  2e-58  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_2552  two component transcriptional regulator, winged helix family  48.68 
 
 
230 aa  226  2e-58  Spirosoma linguale DSM 74  Bacteria  hitchhiker  0.0000276879  normal  0.180215 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  49.55 
 
 
228 aa  224  8e-58  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  51.8 
 
 
225 aa  224  9e-58  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_013061  Phep_3673  response regulator receiver  45.74 
 
 
227 aa  224  1e-57  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  48.89 
 
 
224 aa  223  2e-57  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  49.11 
 
 
226 aa  223  2e-57  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  49.78 
 
 
223 aa  221  4.9999999999999996e-57  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  50.45 
 
 
225 aa  220  9.999999999999999e-57  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  50.45 
 
 
225 aa  220  9.999999999999999e-57  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  50.67 
 
 
226 aa  220  9.999999999999999e-57  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  49.78 
 
 
224 aa  221  9.999999999999999e-57  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  49.78 
 
 
224 aa  220  9.999999999999999e-57  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  50.45 
 
 
225 aa  220  9.999999999999999e-57  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_013132  Cpin_1247  two component transcriptional regulator, winged helix family  46.15 
 
 
235 aa  220  1.9999999999999999e-56  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.464606  normal 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  49.33 
 
 
225 aa  220  1.9999999999999999e-56  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  48.88 
 
 
225 aa  218  7e-56  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  52.02 
 
 
224 aa  218  7e-56  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  46.46 
 
 
230 aa  218  7e-56  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  49.78 
 
 
226 aa  218  8.999999999999998e-56  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  49.33 
 
 
224 aa  217  8.999999999999998e-56  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  50.45 
 
 
224 aa  217  1e-55  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  50.22 
 
 
242 aa  217  1e-55  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  48.43 
 
 
228 aa  216  2e-55  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  48.43 
 
 
225 aa  216  2e-55  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  46.22 
 
 
225 aa  216  2.9999999999999998e-55  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  47.98 
 
 
228 aa  216  2.9999999999999998e-55  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  48.44 
 
 
225 aa  216  2.9999999999999998e-55  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  49.78 
 
 
224 aa  215  4e-55  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  47.98 
 
 
228 aa  215  5e-55  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  48.64 
 
 
230 aa  214  8e-55  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  47.53 
 
 
228 aa  214  9e-55  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  47.53 
 
 
228 aa  214  9e-55  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
CP001637  EcDH1_3058  two component heavy metal response transcriptional regulator, winged helix family  48.43 
 
 
227 aa  213  9.999999999999999e-55  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_009800  EcHS_A0618  DNA-binding transcriptional activator CusR  48.43 
 
 
227 aa  213  9.999999999999999e-55  Escherichia coli HS  Bacteria  hitchhiker  0.000374882  n/a   
 
 
-
 
NC_010468  EcolC_3075  DNA-binding transcriptional activator CusR  48.43 
 
 
227 aa  213  9.999999999999999e-55  Escherichia coli ATCC 8739  Bacteria  normal  0.204173  normal 
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  48.44 
 
 
225 aa  213  9.999999999999999e-55  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_010498  EcSMS35_0588  DNA-binding transcriptional activator CusR  48.43 
 
 
227 aa  213  9.999999999999999e-55  Escherichia coli SMS-3-5  Bacteria  normal  0.372008  normal 
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  47.98 
 
 
235 aa  214  9.999999999999999e-55  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_011353  ECH74115_0651  DNA-binding transcriptional activator CusR  48.43 
 
 
227 aa  213  9.999999999999999e-55  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.589216  normal 
 
 
-
 
CP001509  ECD_00532  DNA-binding response regulator in two-component regulatory system with CusS  48.43 
 
 
227 aa  213  1.9999999999999998e-54  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_0589  DNA-binding transcriptional activator CusR  48.43 
 
 
227 aa  213  1.9999999999999998e-54  Escherichia coli E24377A  Bacteria  normal  0.180273  n/a   
 
 
-
 
NC_012892  B21_00521  hypothetical protein  48.43 
 
 
227 aa  213  1.9999999999999998e-54  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  49.78 
 
 
224 aa  213  1.9999999999999998e-54  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_008573  Shewana3_4296  DNA-binding transcriptional activator CusR  47.09 
 
 
226 aa  212  2.9999999999999995e-54  Shewanella sp. ANA-3  Bacteria  decreased coverage  0.0000252174  normal 
 
 
-
 
NC_009438  Sputcn32_0258  DNA-binding transcriptional activator CusR  47.09 
 
 
226 aa  212  3.9999999999999995e-54  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_15530  heavy metal response regulator, two-component  52.47 
 
 
227 aa  212  3.9999999999999995e-54  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  47.53 
 
 
225 aa  212  3.9999999999999995e-54  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  50.22 
 
 
227 aa  211  4.9999999999999996e-54  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_2234  two component heavy metal response transcriptional regulator  52.21 
 
 
225 aa  211  7e-54  Pseudomonas mendocina ymp  Bacteria  normal  0.162422  normal 
 
 
-
 
NC_009656  PSPA7_3892  putative two-component response regulator  49.33 
 
 
229 aa  211  7.999999999999999e-54  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  48.88 
 
 
223 aa  211  9e-54  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  48.21 
 
 
226 aa  210  1e-53  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  46.43 
 
 
223 aa  210  1e-53  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  50.22 
 
 
231 aa  210  1e-53  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_2007  two component transcriptional regulator  51.11 
 
 
223 aa  211  1e-53  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  47.11 
 
 
227 aa  209  2e-53  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  48.21 
 
 
226 aa  209  2e-53  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  48.18 
 
 
219 aa  210  2e-53  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  48.88 
 
 
225 aa  209  3e-53  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  50.22 
 
 
226 aa  209  3e-53  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  48.88 
 
 
225 aa  209  3e-53  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  48.18 
 
 
227 aa  209  3e-53  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  48.88 
 
 
225 aa  209  3e-53  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  47.32 
 
 
227 aa  209  4e-53  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_3426  DNA-binding transcriptional activator CusR  46.64 
 
 
226 aa  208  5e-53  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  47.98 
 
 
225 aa  208  5e-53  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  47.32 
 
 
228 aa  208  6e-53  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  47.77 
 
 
226 aa  208  6e-53  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  47.98 
 
 
225 aa  208  6e-53  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_010501  PputW619_1675  two component heavy metal response transcriptional regulator  47.77 
 
 
226 aa  207  8e-53  Pseudomonas putida W619  Bacteria  normal  0.294903  normal 
 
 
-
 
NC_008463  PA14_45880  putative two-component response regulator  48.88 
 
 
229 aa  207  9e-53  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal  0.954426 
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  46.12 
 
 
223 aa  207  1e-52  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  46.43 
 
 
229 aa  207  1e-52  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_007912  Sde_1948  response regulator receiver domain-containing protein  47.11 
 
 
226 aa  207  1e-52  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.679676 
 
 
-
 
NC_008009  Acid345_1658  two component transcriptional regulator  48.44 
 
 
230 aa  207  1e-52  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.450735  normal 
 
 
-
 
NC_010831  Cphamn1_0990  two component transcriptional regulator, winged helix family  44.69 
 
 
222 aa  207  1e-52  Chlorobium phaeobacteroides BS1  Bacteria  hitchhiker  0.000957791  decreased coverage  0.0000715536 
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  48.43 
 
 
226 aa  206  2e-52  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_013165  Shel_13760  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  47.56 
 
 
225 aa  206  2e-52  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1742  two component heavy metal response transcriptional regulator, winged helix family  49.33 
 
 
228 aa  206  2e-52  Ralstonia pickettii 12J  Bacteria  normal  normal  0.595604 
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  47.77 
 
 
240 aa  206  2e-52  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  46.88 
 
 
223 aa  206  2e-52  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  45.54 
 
 
225 aa  206  2e-52  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
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