More than 300 homologs were found in PanDaTox collection
for query gene Dfer_2963 on replicon NC_013037
Organism: Dyadobacter fermentans DSM 18053



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_013037  Dfer_2963  two component transcriptional regulator, LuxR family  100 
 
 		 219 aa  454  1e-127  Dyadobacter fermentans DSM 18053  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013730  Slin_5845  two component transcriptional regulator, LuxR family  58.18 
 
 		 219 aa  265  5e-70  Spirosoma linguale DSM 74  Bacteria  normal  1  normal  0.715181 
 
 
-
 
NC_013132  Cpin_2907  two component transcriptional regulator, LuxR family  46.76 
 
 		 222 aa  197  1.0000000000000001e-49  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.0590247  normal  1 
 
 
-
 
NC_013132  Cpin_5476  two component transcriptional regulator, LuxR family  41.82 
 
 		 219 aa  193  1e-48  Chitinophaga pinensis DSM 2588  Bacteria  normal  1  normal  0.21854 
 
 
-
 
NC_009441  Fjoh_0036  two component LuxR family transcriptional regulator  39.91 
 
 		 221 aa  173  1.9999999999999998e-42  Flavobacterium johnsoniae UW101  Bacteria  normal  0.0464925  n/a   
 
 
-
 
NC_010506  Swoo_3747  two component LuxR family transcriptional regulator  39.25 
 
 		 206 aa  158  5e-38  Shewanella woodyi ATCC 51908  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009943  Dole_0029  two component LuxR family transcriptional regulator  35.38 
 
 		 214 aa  146  3e-34  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.317943  n/a   
 
 
-
 
NC_011884  Cyan7425_1401  two component transcriptional regulator, LuxR family  35.05 
 
 		 217 aa  144  1e-33  Cyanothece sp. PCC 7425  Bacteria  normal  1  normal  0.482316 
 
 
-
 
NC_013159  Svir_38420  response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein  34.08 
 
 		 226 aa  142  4e-33  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_004578  PSPTO_2130  DNA-binding response regulator, LuxR family  35.75 
 
 		 222 aa  142  5e-33  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  1  n/a   
 
 
-
 
NC_013730  Slin_0700  two component transcriptional regulator, LuxR family  34.4 
 
 		 218 aa  141  9e-33  Spirosoma linguale DSM 74  Bacteria  hitchhiker  0.00980919  normal  0.316207 
 
 
-
 
NC_013132  Cpin_0010  two component transcriptional regulator, LuxR family  33.64 
 
 		 219 aa  139  1.9999999999999998e-32  Chitinophaga pinensis DSM 2588  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013739  Cwoe_3988  two component transcriptional regulator, LuxR family  35.91 
 
 		 228 aa  140  1.9999999999999998e-32  Conexibacter woesei DSM 14684  Bacteria  normal  0.0354189  normal  0.736565 
 
 
-
 
NC_002939  GSU1293  LuxR family DNA-binding response regulator  35.19 
 
 		 216 aa  139  3e-32  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_010184  BcerKBAB4_5205  two component LuxR family transcriptional regulator  34.91 
 
 		 215 aa  139  3e-32  Bacillus weihenstephanensis KBAB4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007005  Psyr_1940  LuxR response regulator receiver  34.84 
 
 		 222 aa  138  6e-32  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.95717  normal  1 
 
 
-
 
NC_013411  GYMC61_3240  two component transcriptional regulator, LuxR family  34.84 
 
 		 224 aa  138  7.999999999999999e-32  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_007413  Ava_2028  two component LuxR family transcriptional regulator  36.41 
 
 		 219 aa  137  2e-31  Anabaena variabilis ATCC 29413  Bacteria  normal  0.515359  normal  1 
 
 
-
 
NC_013721  HMPREF0424_0644  response regulator receiver domain protein  30.8 
 
 		 261 aa  137  2e-31  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  0.520039 
 
 
-
 
NC_009972  Haur_4778  two component LuxR family transcriptional regulator  36.57 
 
 		 208 aa  135  5e-31  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.00000269792  n/a   
 
 
-
 
NC_012669  Bcav_2822  two component transcriptional regulator, LuxR family  33.18 
 
 		 231 aa  135  6.0000000000000005e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.311075  normal  1 
 
 
-
 
NC_013159  Svir_00210  response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein  33.02 
 
 		 221 aa  135  6.0000000000000005e-31  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  0.133182 
 
 
-
 
NC_009441  Fjoh_1987  two component LuxR family transcriptional regulator  35.91 
 
 		 213 aa  135  6.0000000000000005e-31  Flavobacterium johnsoniae UW101  Bacteria  normal  0.429674  n/a   
 
 
-
 
NC_011658  BCAH187_A5591  DNA-binding response regulator  34.43 
 
 		 215 aa  135  6.0000000000000005e-31  Bacillus cereus AH187  Bacteria  normal  1  n/a   
 
 
-
 
NC_013061  Phep_2735  response regulator receiver  33.94 
 
 		 224 aa  134  9.999999999999999e-31  Pedobacter heparinus DSM 2366  Bacteria  normal  0.0572845  normal  1 
 
 
-
 
NC_011725  BCB4264_A5535  DNA-binding response regulator  33.96 
 
 		 215 aa  134  9.999999999999999e-31  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_009455  DehaBAV1_0409  two component LuxR family transcriptional regulator  36.74 
 
 		 232 aa  134  9.999999999999999e-31  Dehalococcoides sp. BAV1  Bacteria  normal  0.135269  n/a   
 
 
-
 
NC_009457  VC0395_A0896  LuxR family transcriptional regulator  32.09 
 
 		 216 aa  134  9.999999999999999e-31  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_013552  DhcVS_374  DNA-binding response regulator, LuxR family  34.58 
 
 		 232 aa  133  1.9999999999999998e-30  Dehalococcoides sp. VS  Bacteria  hitchhiker  0.0000120759  n/a   
 
 
-
 
NC_003909  BCE_5540  DNA-binding response regulator  33.96 
 
 		 215 aa  133  1.9999999999999998e-30  Bacillus cereus ATCC 10987  Bacteria  normal  1  n/a   
 
 
-
 
NC_007492  Pfl01_3957  two component LuxR family transcriptional regulator  31.8 
 
 		 219 aa  133  1.9999999999999998e-30  Pseudomonas fluorescens Pf0-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007644  Moth_0975  two component LuxR family transcriptional regulator  32.38 
 
 		 222 aa  133  1.9999999999999998e-30  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014212  Mesil_2510  two component transcriptional regulator, LuxR family  33.02 
 
 		 217 aa  133  1.9999999999999998e-30  Meiothermus silvanus DSM 9946  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010571  Oter_0829  two component LuxR family transcriptional regulator  33.49 
 
 		 219 aa  133  1.9999999999999998e-30  Opitutus terrae PB90-1  Bacteria  normal  1  normal  0.0121621 
 
 
-
 
NC_008699  Noca_1020  response regulator receiver  32.26 
 
 		 218 aa  133  1.9999999999999998e-30  Nocardioides sp. JS614  Bacteria  normal  0.648692  n/a   
 
 
-
 
NC_002976  SERP1981  transcriptional regulatory protein DegU, putative  32.41 
 
 		 218 aa  132  3.9999999999999996e-30  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_013204  Elen_1743  two component transcriptional regulator, LuxR family  31.8 
 
 		 214 aa  132  3.9999999999999996e-30  Eggerthella lenta DSM 2243  Bacteria  normal  0.370009  normal  0.039988 
 
 
-
 
NC_014151  Cfla_2391  two component transcriptional regulator, LuxR family  33.76 
 
 		 239 aa  132  3.9999999999999996e-30  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0696687  hitchhiker  0.00128542 
 
 
-
 
NC_005945  BAS5263  DNA-binding response regulator  33.49 
 
 		 215 aa  132  3.9999999999999996e-30  Bacillus anthracis str. Sterne  Bacteria  normal  0.24037  n/a   
 
 
-
 
NC_005957  BT9727_5091  response regulator  33.49 
 
 		 215 aa  132  3.9999999999999996e-30  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_011773  BCAH820_5506  DNA-binding response regulator  33.49 
 
 		 215 aa  132  3.9999999999999996e-30  Bacillus cereus AH820  Bacteria  n/a    normal  1 
 
 
-
 
NC_006274  BCZK5108  response regulator  33.49 
 
 		 215 aa  132  3.9999999999999996e-30  Bacillus cereus E33L  Bacteria  decreased coverage  0.00235048  n/a   
 
 
-
 
NC_007519  Dde_0977  two component LuxR family transcriptional regulator  34.12 
 
 		 223 aa  132  3.9999999999999996e-30  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  decreased coverage  0.00800748  n/a   
 
 
-
 
NC_007530  GBAA_5661  DNA-binding response regulator  33.49 
 
 		 215 aa  132  3.9999999999999996e-30  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_011886  Achl_2270  two component transcriptional regulator, LuxR family  32.33 
 
 		 242 aa  132  3.9999999999999996e-30  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000000000113212 
 
 
-
 
NC_013946  Mrub_0806  two component LuxR family transcriptional regulator  33.18 
 
 		 216 aa  132  3.9999999999999996e-30  Meiothermus ruber DSM 1279  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011662  Tmz1t_1954  two component transcriptional regulator, LuxR family  36.55 
 
 		 220 aa  132  3.9999999999999996e-30  Thauera sp. MZ1T  Bacteria  normal  0.228638  n/a   
 
 
-
 
NC_002936  DET0432  LuxR family DNA-binding response regulator  34.58 
 
 		 232 aa  132  5e-30  Dehalococcoides ethenogenes 195  Bacteria  hitchhiker  0.00543066  n/a   
 
 
-
 
NC_014158  Tpau_2872  two component transcriptional regulator, LuxR family  32.08 
 
 		 218 aa  132  5e-30  Tsukamurella paurometabola DSM 20162  Bacteria  normal  1  n/a   
 
 
-
 
NC_007333  Tfu_2491  LuxR response regulator receiver  33.04 
 
 		 242 aa  132  5e-30  Thermobifida fusca YX  Bacteria  normal  0.470277  n/a   
 
 
-
 
NC_013510  Tcur_4038  two component transcriptional regulator, LuxR family  35.59 
 
 		 253 aa  132  5e-30  Thermomonospora curvata DSM 43183  Bacteria  normal  1  n/a   
 
 
-
 
NC_008255  CHU_1317  response regulator  30.91 
 
 		 220 aa  132  5e-30  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  0.500574  normal  0.0503905 
 
 
-
 
NC_013510  Tcur_4491  two component transcriptional regulator, LuxR family  35.43 
 
 		 225 aa  132  5e-30  Thermomonospora curvata DSM 43183  Bacteria  normal  1  n/a   
 
 
-
 
NC_003295  RSc0292  response regulator transcription regulator protein  33.95 
 
 		 210 aa  131  6e-30  Ralstonia solanacearum GMI1000  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013595  Sros_4468  response regulator receiver protein  34.39 
 
 		 219 aa  131  6e-30  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0876299  normal  0.32237 
 
 
-
 
NC_010682  Rpic_0145  two component transcriptional regulator, LuxR family  33.95 
 
 		 210 aa  131  6e-30  Ralstonia pickettii 12J  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013132  Cpin_1556  two component transcriptional regulator, LuxR family  31.16 
 
 		 222 aa  131  6e-30  Chitinophaga pinensis DSM 2588  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013174  Jden_1873  two component transcriptional regulator, LuxR family  32.6 
 
 		 233 aa  131  7.999999999999999e-30  Jonesia denitrificans DSM 20603  Bacteria  normal  0.145213  normal  0.385799 
 
 
-
 
NC_008578  Acel_1760  two component LuxR family transcriptional regulator  36.04 
 
 		 303 aa  131  9e-30  Acidothermus cellulolyticus 11B  Bacteria  normal  1  normal  0.887336 
 
 
-
 
NC_013947  Snas_2037  two component transcriptional regulator, LuxR family  36.49 
 
 		 225 aa  131  9e-30  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  1  normal  0.137578 
 
 
-
 
NC_012856  Rpic12D_0153  two component transcriptional regulator, LuxR family  33.95 
 
 		 210 aa  131  9e-30  Ralstonia pickettii 12D  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011772  BCG9842_B5417  DNA-binding response regulator  33.02 
 
 		 215 aa  131  9e-30  Bacillus cereus G9842  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011662  Tmz1t_1311  two component transcriptional regulator, LuxR family  34.25 
 
 		 226 aa  130  1.0000000000000001e-29  Thauera sp. MZ1T  Bacteria  normal  0.165019  n/a   
 
 
-
 
NC_009487  SaurJH9_2415  two component LuxR family transcriptional regulator  35.16 
 
 		 217 aa  130  1.0000000000000001e-29  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2463  response regulator receiver  35.16 
 
 		 217 aa  130  1.0000000000000001e-29  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_003909  BCE_1563  DNA-binding response regulator  34.58 
 
 		 210 aa  130  2.0000000000000002e-29  Bacillus cereus ATCC 10987  Bacteria  hitchhiker  0.0000000942452  n/a   
 
 
-
 
NC_005945  BAS1348  DNA-binding response regulator  34.58 
 
 		 210 aa  130  2.0000000000000002e-29  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.0000440829  n/a   
 
 
-
 
NC_005957  BT9727_1322  response regulator  34.58 
 
 		 210 aa  130  2.0000000000000002e-29  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  decreased coverage  7.30192e-17  n/a   
 
 
-
 
NC_006274  BCZK1321  response regulator  34.58 
 
 		 210 aa  129  2.0000000000000002e-29  Bacillus cereus E33L  Bacteria  hitchhiker  0.00000332221  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1363  two component LuxR family transcriptional regulator  34.58 
 
 		 210 aa  130  2.0000000000000002e-29  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.0039551  n/a   
 
 
-
 
NC_013132  Cpin_4294  two component transcriptional regulator, LuxR family  31.19 
 
 		 218 aa  130  2.0000000000000002e-29  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.81327  normal  0.0351026 
 
 
-
 
NC_007530  GBAA_1457  DNA-binding response regulator  34.58 
 
 		 210 aa  130  2.0000000000000002e-29  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  hitchhiker  0.0000538049  n/a   
 
 
-
 
NC_011772  BCG9842_B3849  DNA-binding response regulator  34.58 
 
 		 210 aa  130  2.0000000000000002e-29  Bacillus cereus G9842  Bacteria  decreased coverage  0.0000000308683  hitchhiker  0.000000000350245 
 
 
-
 
NC_011658  BCAH187_A1601  DNA-binding response regulator  34.58 
 
 		 210 aa  130  2.0000000000000002e-29  Bacillus cereus AH187  Bacteria  unclonable  0.00000000136266  n/a   
 
 
-
 
NC_008148  Rxyl_0160  two component LuxR family transcriptional regulator  35.81 
 
 		 212 aa  130  2.0000000000000002e-29  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  1  n/a   
 
 
-
 
NC_012793  GWCH70_3043  two component transcriptional regulator, LuxR family  34.7 
 
 		 225 aa  129  3e-29  Geobacillus sp. WCH70  Bacteria  decreased coverage  0.0000000652561  n/a   
 
 
-
 
NC_014165  Tbis_0775  LuxR family two component transcriptional regulator  34.68 
 
 		 234 aa  129  3e-29  Thermobispora bispora DSM 43833  Bacteria  normal  1  normal  0.336237 
 
 
-
 
NC_013946  Mrub_1071  two component LuxR family transcriptional regulator  35.35 
 
 		 209 aa  129  3e-29  Meiothermus ruber DSM 1279  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009674  Bcer98_1160  two component LuxR family transcriptional regulator  34.42 
 
 		 210 aa  129  4.0000000000000003e-29  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  1  n/a   
 
 
-
 
NC_013757  Gobs_4064  two component transcriptional regulator, LuxR family  34.84 
 
 		 217 aa  129  4.0000000000000003e-29  Geodermatophilus obscurus DSM 43160  Bacteria  normal  1  n/a   
 
 
-
 
NC_008009  Acid345_1691  two component LuxR family transcriptional regulator  34.91 
 
 		 208 aa  129  4.0000000000000003e-29  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  1  normal  0.0637899 
 
 
-
 
NC_013530  Xcel_1618  two component transcriptional regulator, LuxR family  34.25 
 
 		 220 aa  129  4.0000000000000003e-29  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  1  n/a   
 
 
-
 
NC_009953  Sare_4860  two component LuxR family transcriptional regulator  33.48 
 
 		 219 aa  129  4.0000000000000003e-29  Salinispora arenicola CNS-205  Bacteria  normal  0.452521  normal  0.0798716 
 
 
-
 
NC_013730  Slin_5409  two component transcriptional regulator, LuxR family  31.36 
 
 		 223 aa  129  4.0000000000000003e-29  Spirosoma linguale DSM 74  Bacteria  hitchhiker  0.00220575  normal  1 
 
 
-
 
NC_004116  SAG0322  DNA-binding response regulator  34.25 
 
 		 213 aa  128  5.0000000000000004e-29  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_009664  Krad_4217  two component transcriptional regulator, LuxR family  35.56 
 
 		 225 aa  128  5.0000000000000004e-29  Kineococcus radiotolerans SRS30216  Bacteria  decreased coverage  0.000816589  normal  0.757819 
 
 
-
 
NC_007347  Reut_A0121  two component LuxR family transcriptional regulator  34.42 
 
 		 210 aa  128  5.0000000000000004e-29  Ralstonia eutropha JMP134  Bacteria  normal  0.830531  n/a   
 
 
-
 
NC_007973  Rmet_0090  two component LuxR family transcriptional regulator  33.03 
 
 		 210 aa  128  5.0000000000000004e-29  Cupriavidus metallidurans CH34  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011725  BCB4264_A1495  DNA-binding response regulator  34.58 
 
 		 210 aa  129  5.0000000000000004e-29  Bacillus cereus B4264  Bacteria  unclonable  0.0000174821  n/a   
 
 
-
 
NC_013131  Caci_8412  two component transcriptional regulator, LuxR family  33.63 
 
 		 239 aa  128  6e-29  Catenulispora acidiphila DSM 44928  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009654  Mmwyl1_0679  two component LuxR family transcriptional regulator  32.72 
 
 		 213 aa  128  6e-29  Marinomonas sp. MWYL1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009380  Strop_2458  response regulator receiver  33.95 
 
 		 220 aa  128  6e-29  Salinispora tropica CNB-440  Bacteria  normal  0.0554598  normal  1 
 
 
-
 
NC_011899  Hore_21820  two component transcriptional regulator, LuxR family  33.79 
 
 		 211 aa  128  7.000000000000001e-29  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_2782  two component LuxR family transcriptional regulator  32.26 
 
 		 214 aa  128  7.000000000000001e-29  Geobacter uraniireducens Rf4  Bacteria  normal  0.834695  n/a   
 
 
-
 
NC_011773  BCAH820_1531  DNA-binding response regulator  34.11 
 
 		 210 aa  128  7.000000000000001e-29  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  8.64189e-24 
 
 
-
 
NC_013205  Aaci_0516  two component transcriptional regulator, LuxR family  32.41 
 
 		 231 aa  128  8.000000000000001e-29  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  1  n/a   
 
 
-
 
NC_013521  Sked_21600  response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain  31.65 
 
 		 222 aa  128  8.000000000000001e-29  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.49613  normal  1 
 
 
-
 
NC_013530  Xcel_2717  two component transcriptional regulator, LuxR family  34.25 
 
 		 223 aa  127  9.000000000000001e-29  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  1  n/a   
 
 
-
 
NC_013595  Sros_1684  response regulator receiver protein  36.11 
 
 		 207 aa  127  1.0000000000000001e-28  Streptosporangium roseum DSM 43021  Bacteria  normal  1  normal  0.966789 
 
 
-
 
NC_013947  Snas_4479  two component transcriptional regulator, LuxR family  34.39 
 
 		 224 aa  127  1.0000000000000001e-28  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.518456  normal  0.598935 
 
 
-
 
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