More than 300 homologs were found in PanDaTox collection
for query gene SYO3AOP1_0583 on replicon NC_010730
Organism: Sulfurihydrogenibium sp. YO3AOP1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011126  HY04AAS1_0554  Carbamoyl-phosphate synthase L chain ATP-binding  62.5 
 
 
528 aa  676    Hydrogenobaculum sp. Y04AAS1  Bacteria  hitchhiker  0.00479073  n/a   
 
 
-
 
NC_010730  SYO3AOP1_0583  MGS domain protein  100 
 
 
530 aa  1080    Sulfurihydrogenibium sp. YO3AOP1  Bacteria  normal  0.774187  n/a   
 
 
-
 
NC_009483  Gura_1864  carbamoyl-phosphate synthase, large subunit  57.9 
 
 
1082 aa  621  1e-176  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000611023  n/a   
 
 
-
 
NC_008340  Mlg_1981  carbamoyl-phosphate synthase large subunit  55.45 
 
 
1078 aa  619  1e-176  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  decreased coverage  0.00635498 
 
 
-
 
NC_009675  Anae109_2072  carbamoyl phosphate synthase large subunit  55.77 
 
 
1083 aa  612  9.999999999999999e-175  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal  0.471557 
 
 
-
 
NC_007484  Noc_2572  carbamoyl-phosphate synthase, large subunit, glutamine-dependent  56.44 
 
 
1073 aa  610  1e-173  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.0164695  n/a   
 
 
-
 
NC_008609  Ppro_2524  carbamoyl-phosphate synthase, large subunit  56.6 
 
 
1078 aa  608  1e-173  Pelobacter propionicus DSM 2379  Bacteria  normal  0.0237548  n/a   
 
 
-
 
NC_002939  GSU1276  carbamoyl-phosphate synthase, large subunit  56.98 
 
 
1081 aa  605  9.999999999999999e-173  Geobacter sulfurreducens PCA  Bacteria  normal  0.104945  n/a   
 
 
-
 
NC_007517  Gmet_1774  carbamoyl-phosphate synthase large subunit  56.04 
 
 
1081 aa  607  9.999999999999999e-173  Geobacter metallireducens GS-15  Bacteria  decreased coverage  0.00000157385  normal  0.0854041 
 
 
-
 
NC_011146  Gbem_1900  carbamoyl-phosphate synthase, large subunit  56.76 
 
 
1082 aa  607  9.999999999999999e-173  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00662116  n/a   
 
 
-
 
NC_013223  Dret_0320  carbamoyl-phosphate synthase, large subunit  55.7 
 
 
1078 aa  605  9.999999999999999e-173  Desulfohalobium retbaense DSM 5692  Bacteria  unclonable  0.000000336143  normal 
 
 
-
 
NC_012918  GM21_2308  carbamoyl-phosphate synthase, large subunit  56.38 
 
 
1082 aa  603  1.0000000000000001e-171  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010814  Glov_2079  carbamoyl-phosphate synthase, large subunit  55.47 
 
 
1082 aa  603  1.0000000000000001e-171  Geobacter lovleyi SZ  Bacteria  normal  0.0359545  n/a   
 
 
-
 
NC_007794  Saro_2230  carbamoyl phosphate synthase large subunit  55.09 
 
 
1107 aa  604  1.0000000000000001e-171  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.497608  n/a   
 
 
-
 
NC_013173  Dbac_3211  carbamoyl-phosphate synthase, large subunit  57.98 
 
 
1082 aa  602  1.0000000000000001e-171  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013889  TK90_0699  carbamoyl-phosphate synthase, large subunit  55.08 
 
 
1077 aa  604  1.0000000000000001e-171  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.133334  normal  0.0796001 
 
 
-
 
NC_008740  Maqu_3358  carbamoyl-phosphate synthase, large subunit  55.01 
 
 
1072 aa  603  1.0000000000000001e-171  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_4501  carbamoyl-phosphate synthase, large subunit  53.83 
 
 
1073 aa  599  1e-170  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_2306  carbamoyl-phosphate synthase, large subunit  56.65 
 
 
1078 aa  600  1e-170  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_007005  Psyr_4191  carbamoyl phosphate synthase large subunit  53.83 
 
 
1073 aa  598  1e-170  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.725714  normal 
 
 
-
 
NC_007492  Pfl01_0767  carbamoyl phosphate synthase large subunit  54.25 
 
 
1073 aa  598  1e-170  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.256868  normal  0.1584 
 
 
-
 
NC_011891  A2cp1_2208  carbamoyl phosphate synthase large subunit  54.8 
 
 
1077 aa  599  1e-170  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_42930  carbamoyl phosphate synthase large subunit  52.71 
 
 
1073 aa  595  1e-169  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_4034  carbamoyl-phosphate synthase, large subunit  54.49 
 
 
1071 aa  595  1e-169  Marinomonas sp. MWYL1  Bacteria  hitchhiker  0.00188727  normal 
 
 
-
 
NC_007498  Pcar_1612  carbamoyl-phosphate synthase large subunit  56.06 
 
 
1084 aa  597  1e-169  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.00000000225246  n/a   
 
 
-
 
NC_007519  Dde_0333  carbamoyl-phosphate synthase large subunit  55.68 
 
 
1087 aa  595  1e-169  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.639877  n/a   
 
 
-
 
NC_007760  Adeh_1729  carbamoyl phosphate synthase large subunit  54.43 
 
 
1077 aa  598  1e-169  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_008009  Acid345_2197  carbamoyl-phosphate synthase large subunit  54.91 
 
 
1102 aa  596  1e-169  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_0008  carbamoyl phosphate synthase large subunit  54.65 
 
 
1080 aa  596  1e-169  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.196188  normal 
 
 
-
 
NC_008576  Mmc1_3018  carbamoyl-phosphate synthase large subunit  53.67 
 
 
1074 aa  596  1e-169  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_011145  AnaeK_2118  carbamoyl phosphate synthase large subunit  54.61 
 
 
1077 aa  597  1e-169  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2806  carbamoyl-phosphate synthase, large subunit  55.7 
 
 
1077 aa  595  1e-169  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_013422  Hneap_1562  carbamoyl-phosphate synthase, large subunit  55.16 
 
 
1077 aa  592  1e-168  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_009457  VC0395_A1967  carbamoyl phosphate synthase large subunit  53.64 
 
 
1076 aa  594  1e-168  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_009656  PSPA7_5476  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  593  1e-168  Pseudomonas aeruginosa PA7  Bacteria  normal  0.783479  n/a   
 
 
-
 
NC_009511  Swit_0438  carbamoyl phosphate synthase large subunit  54.8 
 
 
1110 aa  592  1e-168  Sphingomonas wittichii RW1  Bacteria  normal  0.561352  normal 
 
 
-
 
NC_007520  Tcr_0879  carbamoyl-phosphate synthase, large subunit  55.38 
 
 
1070 aa  592  1e-168  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_0709  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  592  1e-168  Pseudomonas putida W619  Bacteria  normal  normal  0.0416816 
 
 
-
 
NC_007947  Mfla_0779  carbamoyl-phosphate synthase large subunit  52.82 
 
 
1068 aa  594  1e-168  Methylobacillus flagellatus KT  Bacteria  normal  0.0332696  hitchhiker  0.000231672 
 
 
-
 
NC_008048  Sala_0985  carbamoyl phosphate synthase large subunit  55.47 
 
 
1106 aa  594  1e-168  Sphingopyxis alaskensis RB2256  Bacteria  normal  0.557617  normal 
 
 
-
 
NC_008463  PA14_62910  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  593  1e-168  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_3620  carbamoyl phosphate synthase large subunit  53.08 
 
 
1073 aa  593  1e-168  Pseudomonas mendocina ymp  Bacteria  normal  0.830394  normal 
 
 
-
 
NC_002947  PP_4723  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  591  1e-167  Pseudomonas putida KT2440  Bacteria  normal  hitchhiker  0.00575089 
 
 
-
 
NC_002977  MCA1852  carbamoyl-phosphate synthase, large subunit  53.8 
 
 
1072 aa  588  1e-167  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_4589  carbamoyl phosphate synthase large subunit  52.71 
 
 
1055 aa  589  1e-167  Pseudomonas putida F1  Bacteria  normal  0.387511  normal 
 
 
-
 
NC_011901  Tgr7_0977  carbamoyl-phosphate synthase, large subunit  53.01 
 
 
1072 aa  588  1e-167  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  0.270817  n/a   
 
 
-
 
NC_011138  MADE_02243  carbamoyl phosphate synthase large subunit  54.17 
 
 
1073 aa  590  1e-167  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007955  Mbur_0872  carbamoyl phosphate synthase large subunit  54.22 
 
 
1075 aa  590  1e-167  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_007963  Csal_3085  carbamoyl-phosphate synthase large subunit  54.14 
 
 
1076 aa  590  1e-167  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_2034  carbamoyl phosphate synthase large subunit  52.99 
 
 
1081 aa  590  1e-167  Ralstonia pickettii 12J  Bacteria  normal  0.305177  normal 
 
 
-
 
NC_012856  Rpic12D_1726  carbamoyl phosphate synthase large subunit  52.99 
 
 
1081 aa  590  1e-167  Ralstonia pickettii 12D  Bacteria  normal  normal  0.746976 
 
 
-
 
NC_010322  PputGB1_4724  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  590  1e-167  Pseudomonas putida GB-1  Bacteria  normal  normal 
 
 
-
 
NC_013456  VEA_004478  carbamoyl-phosphate synthase large chain  53.46 
 
 
1077 aa  588  1e-167  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_009719  Plav_2313  carbamoyl-phosphate synthase, large subunit  55.41 
 
 
1079 aa  591  1e-167  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.417995  normal  0.014378 
 
 
-
 
NC_008554  Sfum_3911  carbamoyl phosphate synthase large subunit  54.44 
 
 
1066 aa  590  1e-167  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.123492 
 
 
-
 
NC_007298  Daro_0939  carbamoyl phosphate synthase large subunit  53.66 
 
 
1068 aa  587  1e-166  Dechloromonas aromatica RCB  Bacteria  normal  0.245842  normal 
 
 
-
 
NC_008789  Hhal_1775  carbamoyl-phosphate synthase, large subunit  54.26 
 
 
1073 aa  588  1e-166  Halorhodospira halophila SL1  Bacteria  normal  0.0103005  n/a   
 
 
-
 
NC_007614  Nmul_A0479  carbamoyl-phosphate synthase, large subunit  53.2 
 
 
1075 aa  585  1e-166  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_2728  carbamoyl phosphate synthase large subunit  53.57 
 
 
1077 aa  585  1e-166  Saccharophagus degradans 2-40  Bacteria  normal  0.523784  normal 
 
 
-
 
NC_008345  Sfri_0976  carbamoyl phosphate synthase large subunit  54.51 
 
 
1073 aa  587  1e-166  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008825  Mpe_A1262  carbamoyl-phosphate synthase large subunit  52.95 
 
 
1090 aa  587  1e-166  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.0303508 
 
 
-
 
NC_011080  SNSL254_A0071  carbamoyl phosphate synthase large subunit  53.08 
 
 
1075 aa  583  1.0000000000000001e-165  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  0.423134  normal 
 
 
-
 
NC_003295  RSc1521  carbamoyl phosphate synthase large subunit  52.8 
 
 
1081 aa  583  1.0000000000000001e-165  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_009634  Mevan_0341  carbamoyl-phosphate synthase, large subunit  56.39 
 
 
1081 aa  582  1.0000000000000001e-165  Methanococcus vannielii SB  Archaea  normal  0.756805  n/a   
 
 
-
 
NC_011083  SeHA_C0071  carbamoyl phosphate synthase large subunit  53.08 
 
 
1075 aa  582  1.0000000000000001e-165  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal 
 
 
-
 
NC_010622  Bphy_0874  carbamoyl phosphate synthase large subunit  52.87 
 
 
1084 aa  584  1.0000000000000001e-165  Burkholderia phymatum STM815  Bacteria  normal  normal  0.176638 
 
 
-
 
NC_011312  VSAL_I0586  carbamoyl phosphate synthase large subunit  53.47 
 
 
1076 aa  584  1.0000000000000001e-165  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.221423  n/a   
 
 
-
 
NC_009831  Ssed_3403  carbamoyl phosphate synthase large subunit  53.27 
 
 
1072 aa  583  1.0000000000000001e-165  Shewanella sediminis HAW-EB3  Bacteria  normal  decreased coverage  0.000056188 
 
 
-
 
NC_007517  Gmet_0661  carbamoyl phosphate synthase large subunit  54.63 
 
 
1066 aa  583  1.0000000000000001e-165  Geobacter metallireducens GS-15  Bacteria  decreased coverage  0.00149325  normal  0.138255 
 
 
-
 
NC_010655  Amuc_1251  carbamoyl-phosphate synthase, large subunit  54.22 
 
 
1067 aa  582  1.0000000000000001e-165  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  normal 
 
 
-
 
NC_007604  Synpcc7942_0711  carbamoyl phosphate synthase large subunit  54.63 
 
 
1097 aa  583  1.0000000000000001e-165  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_009783  VIBHAR_00913  carbamoyl phosphate synthase large subunit  53.27 
 
 
1077 aa  583  1.0000000000000001e-165  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_011205  SeD_A0073  carbamoyl phosphate synthase large subunit  53.08 
 
 
1075 aa  583  1.0000000000000001e-165  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  0.841404  normal 
 
 
-
 
NC_009635  Maeo_0045  carbamoyl-phosphate synthase L chain ATP-binding  54.7 
 
 
604 aa  582  1.0000000000000001e-165  Methanococcus aeolicus Nankai-3  Archaea  normal  0.308823  n/a   
 
 
-
 
NC_007973  Rmet_2193  carbamoyl phosphate synthase large subunit  52.99 
 
 
1082 aa  584  1.0000000000000001e-165  Cupriavidus metallidurans CH34  Bacteria  normal  0.0442347  normal  0.129534 
 
 
-
 
NC_011149  SeAg_B0074  carbamoyl phosphate synthase large subunit  53.08 
 
 
1075 aa  583  1.0000000000000001e-165  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A0075  carbamoyl phosphate synthase large subunit  53.08 
 
 
1075 aa  582  1.0000000000000001e-165  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_3577  carbamoyl phosphate synthase large subunit  53.76 
 
 
1072 aa  584  1.0000000000000001e-165  Shewanella woodyi ATCC 51908  Bacteria  normal  normal  0.108884 
 
 
-
 
NC_007347  Reut_A2175  carbamoyl phosphate synthase large subunit  52.22 
 
 
1082 aa  581  1e-164  Ralstonia eutropha JMP134  Bacteria  normal  0.321083  n/a   
 
 
-
 
NC_007510  Bcep18194_A4434  carbamoyl phosphate synthase large subunit  53.46 
 
 
1084 aa  580  1e-164  Burkholderia sp. 383  Bacteria  normal  0.901891  normal 
 
 
-
 
NC_010117  COXBURSA331_A1430  carbamoyl-phosphate synthase, large subunit  53.23 
 
 
1073 aa  581  1e-164  Coxiella burnetii RSA 331  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_2939  carbamoyl phosphate synthase large subunit  53.27 
 
 
1074 aa  578  1e-164  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_010717  PXO_00086  carbamoyl phosphate synthase large subunit  52.6 
 
 
1080 aa  580  1e-164  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_007954  Sden_0996  carbamoyl phosphate synthase large subunit  53.64 
 
 
1075 aa  580  1e-164  Shewanella denitrificans OS217  Bacteria  normal  0.846706  n/a   
 
 
-
 
NC_009484  Acry_0911  carbamoyl phosphate synthase large subunit  53.89 
 
 
1081 aa  580  1e-164  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_008060  Bcen_0811  carbamoyl phosphate synthase large subunit  53.46 
 
 
1084 aa  578  1e-164  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_009727  CBUD_1370  carbamoyl-phosphate synthase large chain  53.03 
 
 
1073 aa  579  1e-164  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  0.636117  n/a   
 
 
-
 
NC_008542  Bcen2424_1292  carbamoyl phosphate synthase large subunit  53.46 
 
 
1084 aa  578  1e-164  Burkholderia cenocepacia HI2424  Bacteria  normal  n/a   
 
 
-
 
NC_010508  Bcenmc03_1263  carbamoyl phosphate synthase large subunit  53.46 
 
 
1084 aa  578  1e-164  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.522789  normal  0.213082 
 
 
-
 
CP001637  EcDH1_3566  carbamoyl-phosphate synthase, large subunit  52.9 
 
 
1073 aa  578  1.0000000000000001e-163  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_1142  carbamoyl phosphate synthase large subunit  53.2 
 
 
1074 aa  576  1.0000000000000001e-163  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009801  EcE24377A_0034  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  577  1.0000000000000001e-163  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
NC_009800  EcHS_A0036  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  577  1.0000000000000001e-163  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_010655  Amuc_0615  carbamoyl phosphate synthase large subunit  52.56 
 
 
1064 aa  577  1.0000000000000001e-163  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  0.120313  normal 
 
 
-
 
NC_011353  ECH74115_0036  carbamoyl phosphate synthase large subunit  52.9 
 
 
1073 aa  577  1.0000000000000001e-163  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal 
 
 
-
 
NC_009665  Shew185_3400  carbamoyl phosphate synthase large subunit  53.2 
 
 
1074 aa  577  1.0000000000000001e-163  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009715  CCV52592_0870  carbamoyl phosphate synthase large subunit  55.32 
 
 
1087 aa  575  1.0000000000000001e-163  Campylobacter curvus 525.92  Bacteria  normal  n/a   
 
 
-
 
NC_008577  Shewana3_0968  carbamoyl phosphate synthase large subunit  53.08 
 
 
1074 aa  577  1.0000000000000001e-163  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_009052  Sbal_3304  carbamoyl phosphate synthase large subunit  53.2 
 
 
1074 aa  577  1.0000000000000001e-163  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_3525  carbamoyl phosphate synthase large subunit  53.2 
 
 
1074 aa  577  1.0000000000000001e-163  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
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