More than 300 homologs were found in PanDaTox collection
for query gene Mesil_0819 on replicon NC_014212
Organism: Meiothermus silvanus DSM 9946



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014212  Mesil_0819  two component transcriptional regulator, winged helix family  100 
 
 
217 aa  427  1e-119  Meiothermus silvanus DSM 9946  Bacteria  normal  0.138732  normal  0.638176 
 
 
-
 
NC_013946  Mrub_1034  two component transcriptional regulator, winged helix family  70.51 
 
 
219 aa  308  4e-83  Meiothermus ruber DSM 1279  Bacteria  normal  0.171933  normal 
 
 
-
 
NC_013946  Mrub_0034  two component transcriptional regulator, winged helix family  48.39 
 
 
220 aa  181  8.000000000000001e-45  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  46.82 
 
 
236 aa  177  2e-43  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_009524  PsycPRwf_0705  two component heavy metal response transcriptional regulator  40.36 
 
 
244 aa  167  1e-40  Psychrobacter sp. PRwf-1  Bacteria  normal  normal  0.591946 
 
 
-
 
NC_010571  Oter_1407  two component transcriptional regulator  42.08 
 
 
265 aa  167  1e-40  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  40.37 
 
 
225 aa  167  1e-40  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_007204  Psyc_1596  two component heavy metal response transcriptional regulator  39.82 
 
 
238 aa  167  2e-40  Psychrobacter arcticus 273-4  Bacteria  normal  normal 
 
 
-
 
NC_009253  Dred_0759  two component transcriptional regulator  39.09 
 
 
223 aa  165  5e-40  Desulfotomaculum reducens MI-1  Bacteria  hitchhiker  0.00128917  n/a   
 
 
-
 
NC_014212  Mesil_3144  two component transcriptional regulator, winged helix family  44.5 
 
 
226 aa  164  6.9999999999999995e-40  Meiothermus silvanus DSM 9946  Bacteria  normal  0.549897  normal 
 
 
-
 
NC_008025  Dgeo_2215  two component transcriptional regulator  47 
 
 
220 aa  164  6.9999999999999995e-40  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_6397  response regulator receiver protein  43.56 
 
 
237 aa  164  8e-40  Streptosporangium roseum DSM 43021  Bacteria  normal  0.680662  normal  0.0804167 
 
 
-
 
NC_009997  Sbal195_0632  two component transcriptional regulator  38.22 
 
 
227 aa  164  9e-40  Shewanella baltica OS195  Bacteria  normal  0.157641  normal 
 
 
-
 
NC_009665  Shew185_0604  two component transcriptional regulator  38.22 
 
 
227 aa  164  9e-40  Shewanella baltica OS185  Bacteria  decreased coverage  0.00704602  n/a   
 
 
-
 
NC_007516  Syncc9605_1618  two component transcriptional regulator  42.61 
 
 
254 aa  164  9e-40  Synechococcus sp. CC9605  Bacteria  normal  normal  0.218753 
 
 
-
 
NC_007335  PMN2A_0436  two component transcriptional regulator  39.06 
 
 
245 aa  164  1.0000000000000001e-39  Prochlorococcus marinus str. NATL2A  Bacteria  normal  0.18923  n/a   
 
 
-
 
NC_008819  NATL1_11471  two-component response regulator, phosphate  39.06 
 
 
245 aa  164  1.0000000000000001e-39  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal  0.0202491 
 
 
-
 
NC_009953  Sare_4064  two component transcriptional regulator  41.82 
 
 
233 aa  163  2.0000000000000002e-39  Salinispora arenicola CNS-205  Bacteria  normal  0.98903  normal  0.0666639 
 
 
-
 
NC_013205  Aaci_2264  two component transcriptional regulator, winged helix family  41.18 
 
 
231 aa  162  3e-39  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  hitchhiker  0.00910741  n/a   
 
 
-
 
NC_007492  Pfl01_3379  two component heavy metal response transcriptional regulator  42.27 
 
 
223 aa  162  5.0000000000000005e-39  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_6588  two component transcriptional regulator  41.55 
 
 
229 aa  161  5.0000000000000005e-39  Frankia sp. EAN1pec  Bacteria  normal  0.13217  normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  41.26 
 
 
226 aa  162  5.0000000000000005e-39  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_007969  Pcryo_0702  two component heavy metal response transcriptional regulator  39.46 
 
 
238 aa  161  6e-39  Psychrobacter cryohalolentis K5  Bacteria  normal  0.149482  normal 
 
 
-
 
NC_008010  Dgeo_2749  two component transcriptional regulator  45.91 
 
 
223 aa  161  6e-39  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.513844  n/a   
 
 
-
 
NC_008148  Rxyl_3017  two component transcriptional regulator  44.34 
 
 
225 aa  161  6e-39  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009668  Oant_3252  two component transcriptional regulator  40.83 
 
 
220 aa  161  7e-39  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  41.89 
 
 
240 aa  161  8.000000000000001e-39  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  40.81 
 
 
228 aa  161  8.000000000000001e-39  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007347  Reut_A2490  heavy metal response regulator  44.29 
 
 
228 aa  160  9e-39  Ralstonia eutropha JMP134  Bacteria  normal  0.289616  n/a   
 
 
-
 
NC_009380  Strop_3686  response regulator receiver  41.36 
 
 
233 aa  161  9e-39  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_5144  two component transcriptional regulator, winged helix family  41.36 
 
 
236 aa  160  2e-38  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.204078  normal  0.858106 
 
 
-
 
NC_009802  CCC13826_1969  response regulator receiver domain-containing protein  41.2 
 
 
219 aa  159  2e-38  Campylobacter concisus 13826  Bacteria  normal  0.478098  n/a   
 
 
-
 
NC_013947  Snas_4900  two component transcriptional regulator, winged helix family  45.25 
 
 
221 aa  160  2e-38  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.196174  normal 
 
 
-
 
NC_013510  Tcur_0578  two component transcriptional regulator, winged helix family  41.44 
 
 
244 aa  159  2e-38  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_5018  two component transcriptional regulator, winged helix family  42.6 
 
 
226 aa  159  3e-38  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_009457  VC0395_A1244  DNA-binding response regulator  41.36 
 
 
219 aa  159  3e-38  Vibrio cholerae O395  Bacteria  hitchhiker  0.000000000000551267  n/a   
 
 
-
 
NC_013456  VEA_003784  two-component system response regulator QseB  40.09 
 
 
219 aa  159  4e-38  Vibrio sp. Ex25  Bacteria  hitchhiker  0.000147394  n/a   
 
 
-
 
NC_009523  RoseRS_2290  two component transcriptional regulator  44.29 
 
 
224 aa  159  4e-38  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  42.47 
 
 
228 aa  159  4e-38  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  39.91 
 
 
232 aa  158  5e-38  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_014248  Aazo_2223  winged helix family two component transcriptional regulator  39.73 
 
 
229 aa  158  6e-38  'Nostoc azollae' 0708  Bacteria  normal  0.335669  n/a   
 
 
-
 
NC_013946  Mrub_0644  two component transcriptional regulator, winged helix family  45.33 
 
 
218 aa  158  6e-38  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_011773  BCAH820_0627  DNA-binding response regulator  40.89 
 
 
223 aa  158  7e-38  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_005945  BAS0540  DNA-binding response regulator  40.89 
 
 
223 aa  157  9e-38  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_00315  probable two component response regulator transcription regulator protein  41.44 
 
 
227 aa  157  9e-38  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_0571  DNA-binding response regulator  40.89 
 
 
223 aa  157  9e-38  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_5468  two component transcriptional regulator, winged helix family  45.13 
 
 
223 aa  157  9e-38  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  42.01 
 
 
230 aa  157  9e-38  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  42.47 
 
 
228 aa  157  9e-38  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  40.17 
 
 
239 aa  157  9e-38  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  42.47 
 
 
228 aa  157  9e-38  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  40.83 
 
 
223 aa  157  1e-37  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  42.41 
 
 
231 aa  157  1e-37  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_2487  two component transcriptional regulator  44.75 
 
 
224 aa  157  1e-37  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.431556  normal 
 
 
-
 
NC_011662  Tmz1t_1421  two component transcriptional regulator, winged helix family  43.26 
 
 
230 aa  157  1e-37  Thauera sp. MZ1T  Bacteria  normal  0.0283266  n/a   
 
 
-
 
NC_003909  BCE_0634  DNA-binding response regulator  40.89 
 
 
223 aa  156  2e-37  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_009720  Xaut_3399  two component transcriptional regulator  43.32 
 
 
223 aa  157  2e-37  Xanthobacter autotrophicus Py2  Bacteria  normal  normal 
 
 
-
 
NC_007333  Tfu_1330  response regulator receiver  40.09 
 
 
219 aa  156  2e-37  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_2440  two component transcriptional regulator  38.36 
 
 
222 aa  157  2e-37  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0936231  normal 
 
 
-
 
NC_007777  Francci3_0234  two component transcriptional regulator  41.55 
 
 
242 aa  157  2e-37  Frankia sp. CcI3  Bacteria  normal  normal  0.925989 
 
 
-
 
NC_009504  BOV_A0210  DNA-binding response regulator  37.9 
 
 
225 aa  156  2e-37  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_009783  VIBHAR_02658  hypothetical protein  40.55 
 
 
219 aa  156  2e-37  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  42.27 
 
 
228 aa  156  2e-37  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_005957  BT9727_0482  response regulator  40.89 
 
 
223 aa  156  3e-37  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  41.07 
 
 
230 aa  156  3e-37  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_0293  two component transcriptional regulator, winged helix family  44.64 
 
 
226 aa  155  3e-37  Conexibacter woesei DSM 14684  Bacteria  normal  0.591061  normal  0.658536 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  41.1 
 
 
227 aa  155  3e-37  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  39.46 
 
 
226 aa  155  3e-37  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_010184  BcerKBAB4_0485  two component transcriptional regulator  40 
 
 
223 aa  155  3e-37  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  40.44 
 
 
228 aa  156  3e-37  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_011658  BCAH187_A0702  DNA-binding response regulator  41.33 
 
 
223 aa  156  3e-37  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  41.55 
 
 
219 aa  155  3e-37  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  42.34 
 
 
224 aa  155  4e-37  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_006274  BCZK0484  response regulator  40.44 
 
 
229 aa  155  4e-37  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  40.45 
 
 
222 aa  155  4e-37  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  41.52 
 
 
226 aa  155  5.0000000000000005e-37  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_011772  BCG9842_B4731  DNA-binding response regulator  40 
 
 
223 aa  155  5.0000000000000005e-37  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_013161  Cyan8802_4261  two component transcriptional regulator, winged helix family  40.81 
 
 
224 aa  155  6e-37  Cyanothece sp. PCC 8802  Bacteria  normal  0.906422  normal  0.0109867 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  40.54 
 
 
223 aa  155  6e-37  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_009091  P9301_12431  two-component response regulator, phosphate  39.83 
 
 
242 aa  155  6e-37  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  0.15803  n/a   
 
 
-
 
NC_007413  Ava_4085  two component transcriptional regulator  39.91 
 
 
225 aa  154  8e-37  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.320847 
 
 
-
 
NC_008009  Acid345_3061  two component transcriptional regulator  39.56 
 
 
229 aa  154  8e-37  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.296421  normal 
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  42.92 
 
 
224 aa  154  9e-37  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  42.47 
 
 
232 aa  154  9e-37  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  40.53 
 
 
229 aa  154  1e-36  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  42.01 
 
 
228 aa  154  1e-36  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_013131  Caci_0208  two component transcriptional regulator, winged helix family  42.34 
 
 
238 aa  154  1e-36  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  38.57 
 
 
224 aa  154  1e-36  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011726  PCC8801_4222  two component transcriptional regulator, winged helix family  40.81 
 
 
224 aa  154  1e-36  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_007577  PMT9312_0717  two component transcriptional regulator  40.26 
 
 
242 aa  154  1e-36  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  41.36 
 
 
228 aa  154  1e-36  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  40.09 
 
 
224 aa  154  1e-36  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_013161  Cyan8802_1445  two component transcriptional regulator, winged helix family  41.26 
 
 
225 aa  154  1e-36  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_1416  two component transcriptional regulator, winged helix family  41.26 
 
 
225 aa  154  1e-36  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  43.12 
 
 
226 aa  154  1e-36  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A0608  DNA-binding response regulator  40 
 
 
223 aa  154  1e-36  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  41.18 
 
 
228 aa  153  2e-36  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  42.66 
 
 
226 aa  153  2e-36  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011726  PCC8801_3668  two component transcriptional regulator, winged helix family  40.09 
 
 
635 aa  153  2e-36  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_009717  Xaut_4961  two component transcriptional regulator  43.52 
 
 
220 aa  153  2e-36  Xanthobacter autotrophicus Py2  Bacteria  normal  0.675974  normal  0.952404 
 
 
-
 
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