More than 300 homologs were found in PanDaTox collection
for query gene Mrub_1034 on replicon NC_013946
Organism: Meiothermus ruber DSM 1279



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013946  Mrub_1034  two component transcriptional regulator, winged helix family  100 
 
 
219 aa  429  1e-119  Meiothermus ruber DSM 1279  Bacteria  normal  0.171933  normal 
 
 
-
 
NC_014212  Mesil_0819  two component transcriptional regulator, winged helix family  70.51 
 
 
217 aa  308  4e-83  Meiothermus silvanus DSM 9946  Bacteria  normal  0.138732  normal  0.638176 
 
 
-
 
NC_014212  Mesil_3144  two component transcriptional regulator, winged helix family  46.36 
 
 
226 aa  186  2e-46  Meiothermus silvanus DSM 9946  Bacteria  normal  0.549897  normal 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  43.5 
 
 
225 aa  182  3e-45  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_008010  Dgeo_2749  two component transcriptional regulator  49.77 
 
 
223 aa  181  6e-45  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.513844  n/a   
 
 
-
 
NC_013946  Mrub_0034  two component transcriptional regulator, winged helix family  50 
 
 
220 aa  179  2.9999999999999997e-44  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  44.69 
 
 
226 aa  176  3e-43  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  44.25 
 
 
228 aa  176  4e-43  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007912  Sde_1948  response regulator receiver domain-containing protein  44.39 
 
 
226 aa  174  9.999999999999999e-43  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.679676 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  41.78 
 
 
226 aa  168  7e-41  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_009668  Oant_3252  two component transcriptional regulator  42.27 
 
 
220 aa  167  1e-40  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  42.86 
 
 
228 aa  167  1e-40  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  42.86 
 
 
228 aa  166  2e-40  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  42.41 
 
 
230 aa  166  2e-40  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  42.86 
 
 
228 aa  166  2e-40  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_007517  Gmet_1026  two component transcriptional regulator  42.34 
 
 
224 aa  166  2.9999999999999998e-40  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.000442073 
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  43.11 
 
 
240 aa  166  2.9999999999999998e-40  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  43.3 
 
 
228 aa  165  4e-40  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_007347  Reut_A2490  heavy metal response regulator  43.75 
 
 
228 aa  165  4e-40  Ralstonia eutropha JMP134  Bacteria  normal  0.289616  n/a   
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  45.58 
 
 
236 aa  166  4e-40  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  42.79 
 
 
219 aa  165  4e-40  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  41.26 
 
 
223 aa  165  5e-40  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_013037  Dfer_2762  two component transcriptional regulator, winged helix family  42.04 
 
 
225 aa  165  5e-40  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  42.41 
 
 
227 aa  165  5.9999999999999996e-40  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  42.41 
 
 
223 aa  164  8e-40  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_009511  Swit_3444  two component transcriptional regulator  42.27 
 
 
220 aa  164  1.0000000000000001e-39  Sphingomonas wittichii RW1  Bacteria  normal  0.112849  normal  0.384843 
 
 
-
 
NC_007335  PMN2A_0436  two component transcriptional regulator  40.17 
 
 
245 aa  163  2.0000000000000002e-39  Prochlorococcus marinus str. NATL2A  Bacteria  normal  0.18923  n/a   
 
 
-
 
NC_011138  MADE_00315  probable two component response regulator transcription regulator protein  40.09 
 
 
227 aa  163  2.0000000000000002e-39  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  43.5 
 
 
232 aa  162  3e-39  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  41.89 
 
 
226 aa  162  3e-39  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_009253  Dred_0759  two component transcriptional regulator  40.99 
 
 
223 aa  162  3e-39  Desulfotomaculum reducens MI-1  Bacteria  hitchhiker  0.00128917  n/a   
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  42.86 
 
 
228 aa  162  3e-39  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_007204  Psyc_1596  two component heavy metal response transcriptional regulator  40.89 
 
 
238 aa  162  4.0000000000000004e-39  Psychrobacter arcticus 273-4  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  43.5 
 
 
283 aa  162  4.0000000000000004e-39  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_010571  Oter_1407  two component transcriptional regulator  42.6 
 
 
265 aa  162  4.0000000000000004e-39  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  44.39 
 
 
226 aa  162  5.0000000000000005e-39  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_014148  Plim_0003  response regulator receiver  45.21 
 
 
235 aa  162  5.0000000000000005e-39  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  42.41 
 
 
228 aa  162  5.0000000000000005e-39  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_008819  NATL1_11471  two-component response regulator, phosphate  39.74 
 
 
245 aa  161  6e-39  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal  0.0202491 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  44.39 
 
 
226 aa  161  6e-39  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_4508  two component transcriptional regulator, winged helix family  45.5 
 
 
231 aa  161  7e-39  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  39.65 
 
 
224 aa  161  7e-39  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  42.34 
 
 
223 aa  161  7e-39  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_3017  two component transcriptional regulator  45.29 
 
 
225 aa  161  8.000000000000001e-39  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009524  PsycPRwf_0705  two component heavy metal response transcriptional regulator  39.56 
 
 
244 aa  160  9e-39  Psychrobacter sp. PRwf-1  Bacteria  normal  normal  0.591946 
 
 
-
 
NC_009486  Tpet_0521  two component transcriptional regulator  39.55 
 
 
223 aa  160  1e-38  Thermotoga petrophila RKU-1  Bacteria  normal  0.720367  n/a   
 
 
-
 
NC_007492  Pfl01_3379  two component heavy metal response transcriptional regulator  41.26 
 
 
223 aa  160  1e-38  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010070  Bmul_6295  two component heavy metal response transcriptional regulator  42.34 
 
 
223 aa  160  1e-38  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.803537  normal  0.219108 
 
 
-
 
NC_007794  Saro_2066  two component transcriptional regulator  41.82 
 
 
225 aa  160  1e-38  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  n/a   
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  46.64 
 
 
226 aa  160  2e-38  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_2440  two component transcriptional regulator  39.09 
 
 
222 aa  159  2e-38  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0936231  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  40.72 
 
 
225 aa  160  2e-38  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  41.89 
 
 
223 aa  159  2e-38  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  40.72 
 
 
225 aa  160  2e-38  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  40.72 
 
 
225 aa  160  2e-38  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  42.22 
 
 
226 aa  159  2e-38  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  40.18 
 
 
224 aa  160  2e-38  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009802  CCC13826_1969  response regulator receiver domain-containing protein  39.73 
 
 
219 aa  159  3e-38  Campylobacter concisus 13826  Bacteria  normal  0.478098  n/a   
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  43.95 
 
 
235 aa  159  3e-38  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_009380  Strop_3686  response regulator receiver  41.7 
 
 
233 aa  159  3e-38  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  43.3 
 
 
224 aa  159  4e-38  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_009921  Franean1_6588  two component transcriptional regulator  41.96 
 
 
229 aa  159  4e-38  Frankia sp. EAN1pec  Bacteria  normal  0.13217  normal 
 
 
-
 
NC_009767  Rcas_2599  two component transcriptional regulator  45.98 
 
 
232 aa  159  4e-38  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.268704  normal 
 
 
-
 
NC_011831  Cagg_3502  two component transcriptional regulator, winged helix family  45.98 
 
 
232 aa  159  4e-38  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_013757  Gobs_4657  two component transcriptional regulator, winged helix family  41.78 
 
 
240 aa  159  4e-38  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  41.89 
 
 
223 aa  159  4e-38  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_013124  Afer_0703  two component transcriptional regulator, winged helix family  42.22 
 
 
236 aa  158  5e-38  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_009953  Sare_4064  two component transcriptional regulator  41.26 
 
 
233 aa  158  5e-38  Salinispora arenicola CNS-205  Bacteria  normal  0.98903  normal  0.0666639 
 
 
-
 
NC_009654  Mmwyl1_0224  two component transcriptional regulator  40.83 
 
 
221 aa  158  5e-38  Marinomonas sp. MWYL1  Bacteria  normal  0.0104787  normal 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  39.29 
 
 
224 aa  158  5e-38  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007974  Rmet_5672  DNA-binding response regulator  43.3 
 
 
228 aa  158  5e-38  Cupriavidus metallidurans CH34  Bacteria  normal  normal 
 
 
-
 
NC_004116  SAG2122  DNA-binding response regulator  40.09 
 
 
223 aa  158  6e-38  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_6397  response regulator receiver protein  42.54 
 
 
237 aa  158  6e-38  Streptosporangium roseum DSM 43021  Bacteria  normal  0.680662  normal  0.0804167 
 
 
-
 
NC_013739  Cwoe_0293  two component transcriptional regulator, winged helix family  41.89 
 
 
226 aa  158  7e-38  Conexibacter woesei DSM 14684  Bacteria  normal  0.591061  normal  0.658536 
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  40.09 
 
 
225 aa  158  7e-38  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  42.61 
 
 
223 aa  158  7e-38  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007969  Pcryo_0702  two component heavy metal response transcriptional regulator  39.11 
 
 
238 aa  158  7e-38  Psychrobacter cryohalolentis K5  Bacteria  normal  0.149482  normal 
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  42.54 
 
 
223 aa  157  8e-38  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  40.54 
 
 
225 aa  157  8e-38  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_013093  Amir_5468  two component transcriptional regulator, winged helix family  41.85 
 
 
223 aa  157  8e-38  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_1675  two component heavy metal response transcriptional regulator  41.78 
 
 
226 aa  157  8e-38  Pseudomonas putida W619  Bacteria  normal  0.294903  normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  42.22 
 
 
226 aa  157  9e-38  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  42.22 
 
 
226 aa  157  1e-37  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  39.91 
 
 
225 aa  157  1e-37  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  38.77 
 
 
230 aa  157  1e-37  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  37.67 
 
 
238 aa  157  1e-37  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_007971  Rmet_6111  regulator protein CopR  41.7 
 
 
228 aa  157  1e-37  Cupriavidus metallidurans CH34  Bacteria  normal  0.110686  normal  0.158568 
 
 
-
 
NC_008048  Sala_0801  two component transcriptional regulator  41.36 
 
 
221 aa  157  1e-37  Sphingopyxis alaskensis RB2256  Bacteria  normal  normal  0.0203691 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  41.44 
 
 
223 aa  157  1e-37  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  41.44 
 
 
223 aa  157  1e-37  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_010468  EcolC_3412  two component heavy metal response transcriptional regulator  40.27 
 
 
226 aa  157  2e-37  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_10613  two component system DNA binding transcriptional regulatory protein tcrA  43.95 
 
 
253 aa  156  2e-37  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.0000000499525  normal  0.750249 
 
 
-
 
NC_013205  Aaci_2264  two component transcriptional regulator, winged helix family  42.34 
 
 
231 aa  157  2e-37  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  hitchhiker  0.00910741  n/a   
 
 
-
 
NC_013947  Snas_4900  two component transcriptional regulator, winged helix family  42.27 
 
 
221 aa  156  2e-37  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.196174  normal 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  43.04 
 
 
224 aa  156  2e-37  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  40.09 
 
 
225 aa  156  2e-37  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  40.54 
 
 
225 aa  156  2e-37  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  40.54 
 
 
225 aa  156  2e-37  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_008578  Acel_1449  two component transcriptional regulator  41.18 
 
 
246 aa  157  2e-37  Acidothermus cellulolyticus 11B  Bacteria  normal  0.566781  normal 
 
 
-
 
NC_008781  Pnap_1535  two component transcriptional regulator  41.74 
 
 
222 aa  156  2e-37  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
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