More than 300 homologs were found in PanDaTox collection
for query gene Tpau_1622 on replicon NC_014158
Organism: Tsukamurella paurometabola DSM 20162



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014158  Tpau_1622  two component transcriptional regulator, winged helix family  100 
 
 
223 aa  436  1e-121  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.153936  n/a   
 
 
-
 
NC_013093  Amir_5468  two component transcriptional regulator, winged helix family  57.47 
 
 
223 aa  240  2e-62  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_1613  response regulator receiver  54.34 
 
 
225 aa  235  4e-61  Nocardioides sp. JS614  Bacteria  normal  0.97266  n/a   
 
 
-
 
NC_013595  Sros_3423  response regulator receiver protein  53.42 
 
 
224 aa  233  1.0000000000000001e-60  Streptosporangium roseum DSM 43021  Bacteria  normal  0.699539  normal  0.107362 
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  54.79 
 
 
225 aa  227  1e-58  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_013441  Gbro_1324  response regulator receiver  54.34 
 
 
223 aa  225  5.0000000000000005e-58  Gordonia bronchialis DSM 43247  Bacteria  normal  0.88989  n/a   
 
 
-
 
NC_013947  Snas_4842  two component transcriptional regulator, winged helix family  55.25 
 
 
225 aa  224  8e-58  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.649395  normal 
 
 
-
 
NC_008537  Arth_4535  two component transcriptional regulator  51.14 
 
 
227 aa  224  9e-58  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_1598  response regulator receiver  51.82 
 
 
226 aa  222  3e-57  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_37500  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  53.42 
 
 
225 aa  222  4e-57  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.0213695  normal 
 
 
-
 
NC_013124  Afer_0703  two component transcriptional regulator, winged helix family  48.42 
 
 
236 aa  218  3.9999999999999997e-56  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_0102  response regulator receiver protein  53.88 
 
 
222 aa  219  3.9999999999999997e-56  Streptosporangium roseum DSM 43021  Bacteria  normal  0.294663  normal 
 
 
-
 
NC_009664  Krad_1806  two component transcriptional regulator, winged helix family  52.97 
 
 
225 aa  216  2e-55  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0205791  normal  0.258829 
 
 
-
 
NC_014151  Cfla_1294  two component transcriptional regulator, winged helix family  55.45 
 
 
218 aa  214  8e-55  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0476117  hitchhiker  0.00354598 
 
 
-
 
NC_013521  Sked_01690  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  51.36 
 
 
217 aa  207  1e-52  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.459553  normal  0.405302 
 
 
-
 
NC_009380  Strop_1594  response regulator receiver  54.79 
 
 
219 aa  203  2e-51  Salinispora tropica CNB-440  Bacteria  normal  0.349405  normal 
 
 
-
 
NC_009953  Sare_1554  two component transcriptional regulator  53.42 
 
 
218 aa  201  8e-51  Salinispora arenicola CNS-205  Bacteria  normal  0.083917  hitchhiker  0.00805861 
 
 
-
 
NC_013093  Amir_0753  two component transcriptional regulator, winged helix family  48.65 
 
 
241 aa  192  5e-48  Actinosynnema mirum DSM 43827  Bacteria  normal  0.407347  n/a   
 
 
-
 
NC_013165  Shel_13760  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  48.86 
 
 
225 aa  191  6e-48  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  46.82 
 
 
235 aa  190  1e-47  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  47.27 
 
 
283 aa  188  5e-47  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_009565  TBFG_10613  two component system DNA binding transcriptional regulatory protein tcrA  44.8 
 
 
253 aa  187  2e-46  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.0000000499525  normal  0.750249 
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  43.32 
 
 
225 aa  184  8e-46  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_008009  Acid345_0311  two component transcriptional regulator  43.89 
 
 
232 aa  183  2.0000000000000003e-45  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal  0.280613 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  47 
 
 
225 aa  179  4e-44  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  47 
 
 
225 aa  178  4.999999999999999e-44  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  43.78 
 
 
231 aa  178  5.999999999999999e-44  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_1610  two component transcriptional regulator  42.01 
 
 
232 aa  175  6e-43  Nocardioides sp. JS614  Bacteria  normal  0.496365  n/a   
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  39.82 
 
 
224 aa  174  8e-43  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  41.94 
 
 
223 aa  174  9.999999999999999e-43  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009441  Fjoh_3400  two component transcriptional regulator  41.44 
 
 
224 aa  174  9.999999999999999e-43  Flavobacterium johnsoniae UW101  Bacteria  normal  0.105495  n/a   
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  39.82 
 
 
224 aa  172  1.9999999999999998e-42  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  44.7 
 
 
225 aa  172  2.9999999999999996e-42  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  44.24 
 
 
224 aa  172  2.9999999999999996e-42  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_010676  Bphyt_5873  two component heavy metal response transcriptional regulator, winged helix family  41.94 
 
 
228 aa  172  2.9999999999999996e-42  Burkholderia phytofirmans PsJN  Bacteria  normal  0.247228  normal 
 
 
-
 
NC_008699  Noca_2062  two component transcriptional regulator  46.61 
 
 
228 aa  172  2.9999999999999996e-42  Nocardioides sp. JS614  Bacteria  normal  0.0133309  n/a   
 
 
-
 
NC_007952  Bxe_B2069  two component heavy metal response transcriptional regulator  41.94 
 
 
228 aa  172  2.9999999999999996e-42  Burkholderia xenovorans LB400  Bacteria  normal  0.0102482  normal 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  44.24 
 
 
224 aa  172  2.9999999999999996e-42  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  40.27 
 
 
224 aa  172  3.9999999999999995e-42  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_0293  two component transcriptional regulator, winged helix family  44.09 
 
 
226 aa  172  3.9999999999999995e-42  Conexibacter woesei DSM 14684  Bacteria  normal  0.591061  normal  0.658536 
 
 
-
 
NC_010681  Bphyt_3267  two component transcriptional regulator, winged helix family  43.38 
 
 
220 aa  171  5e-42  Burkholderia phytofirmans PsJN  Bacteria  normal  0.387524  normal 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  40.99 
 
 
224 aa  171  5.999999999999999e-42  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_013730  Slin_4793  two component transcriptional regulator, winged helix family  40.81 
 
 
225 aa  171  5.999999999999999e-42  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_010622  Bphy_0469  two component transcriptional regulator  43.84 
 
 
220 aa  171  7.999999999999999e-42  Burkholderia phymatum STM815  Bacteria  normal  0.601273  normal  0.0513669 
 
 
-
 
NC_008699  Noca_1559  response regulator receiver  46.15 
 
 
228 aa  171  7.999999999999999e-42  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  44.95 
 
 
228 aa  171  1e-41  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_002977  MCA2330  DNA-binding response regulator  43.38 
 
 
228 aa  171  1e-41  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  39.82 
 
 
223 aa  170  2e-41  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  44.7 
 
 
224 aa  170  2e-41  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  38.01 
 
 
223 aa  170  2e-41  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  40.55 
 
 
223 aa  169  3e-41  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  42.4 
 
 
225 aa  169  3e-41  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  40.45 
 
 
224 aa  169  5e-41  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_007951  Bxe_A0699  two component transcriptional regulator  42.01 
 
 
220 aa  168  6e-41  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  44.04 
 
 
226 aa  168  6e-41  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  43.78 
 
 
225 aa  168  7e-41  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  40.45 
 
 
224 aa  167  8e-41  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  39.37 
 
 
224 aa  167  9e-41  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  40 
 
 
224 aa  167  1e-40  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  39.09 
 
 
238 aa  167  1e-40  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  43.58 
 
 
226 aa  167  1e-40  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_010625  Bphy_6519  two component heavy metal response transcriptional regulator  41.94 
 
 
228 aa  167  1e-40  Burkholderia phymatum STM815  Bacteria  normal  normal  0.0435386 
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  39.01 
 
 
224 aa  167  1e-40  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_011138  MADE_03339  Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain  40.91 
 
 
226 aa  167  2e-40  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  40.45 
 
 
225 aa  166  2e-40  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS2999  DNA-binding response regulator  40.45 
 
 
224 aa  166  2e-40  Bacillus anthracis str. Sterne  Bacteria  normal  0.227145  n/a   
 
 
-
 
NC_007530  GBAA_3229  DNA-binding response regulator  40.45 
 
 
224 aa  166  2e-40  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  41.63 
 
 
240 aa  166  2e-40  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_008009  Acid345_1658  two component transcriptional regulator  42.27 
 
 
230 aa  167  2e-40  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.450735  normal 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  38.67 
 
 
230 aa  167  2e-40  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  45.16 
 
 
225 aa  166  2.9999999999999998e-40  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  45.16 
 
 
225 aa  166  2.9999999999999998e-40  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  43.78 
 
 
226 aa  166  2.9999999999999998e-40  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  45.16 
 
 
225 aa  166  2.9999999999999998e-40  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  42.66 
 
 
226 aa  166  4e-40  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_011080  SNSL254_A1191  transcriptional regulatory protein YedW  41.44 
 
 
226 aa  166  4e-40  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_0528  two component heavy metal response transcriptional regulator  41.47 
 
 
223 aa  165  4e-40  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011205  SeD_A1171  transcriptional regulatory protein YedW  41.44 
 
 
226 aa  166  4e-40  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  39.37 
 
 
223 aa  165  4e-40  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  44.24 
 
 
226 aa  165  5e-40  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_3379  two component heavy metal response transcriptional regulator  44.04 
 
 
223 aa  165  5.9999999999999996e-40  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  40.45 
 
 
223 aa  165  5.9999999999999996e-40  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011149  SeAg_B1055  transcriptional regulatory protein YedW  41.44 
 
 
226 aa  165  5.9999999999999996e-40  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A1160  transcriptional regulatory protein YedW  41.44 
 
 
226 aa  165  5.9999999999999996e-40  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  normal  0.728212 
 
 
-
 
NC_014148  Plim_0003  response regulator receiver  45.5 
 
 
235 aa  165  5.9999999999999996e-40  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  42.99 
 
 
228 aa  164  6.9999999999999995e-40  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_011830  Dhaf_2231  two component transcriptional regulator, winged helix family  42.34 
 
 
226 aa  164  6.9999999999999995e-40  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  43.32 
 
 
225 aa  164  6.9999999999999995e-40  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  42.66 
 
 
226 aa  164  9e-40  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  43.78 
 
 
229 aa  164  1.0000000000000001e-39  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  40 
 
 
224 aa  164  1.0000000000000001e-39  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_007974  Rmet_5331  transcriptional regulator two components regulatory system  42.01 
 
 
225 aa  164  1.0000000000000001e-39  Cupriavidus metallidurans CH34  Bacteria  normal  0.0274603  normal 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  43.78 
 
 
225 aa  164  1.0000000000000001e-39  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_010468  EcolC_3412  two component heavy metal response transcriptional regulator  39.27 
 
 
226 aa  163  2.0000000000000002e-39  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  41.1 
 
 
226 aa  163  2.0000000000000002e-39  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  42.2 
 
 
226 aa  163  2.0000000000000002e-39  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_008148  Rxyl_3017  two component transcriptional regulator  43.44 
 
 
225 aa  163  2.0000000000000002e-39  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  42.08 
 
 
228 aa  163  2.0000000000000002e-39  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_013159  Svir_31270  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  39.46 
 
 
221 aa  163  2.0000000000000002e-39  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.014564  normal  0.249814 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  41.01 
 
 
225 aa  163  2.0000000000000002e-39  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
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