More than 300 homologs were found in PanDaTox collection
for query gene Mvan_2389 on replicon NC_008726
Organism: Mycobacterium vanbaalenii PYR-1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_008726  Mvan_2389  two component transcriptional regulator  100 
 
 
219 aa  436  1e-121  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.753035  normal  0.0318145 
 
 
-
 
NC_009338  Mflv_3998  two component transcriptional regulator  73.18 
 
 
220 aa  313  1.9999999999999998e-84  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.278973  normal  0.137181 
 
 
-
 
NC_013159  Svir_31270  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  69.27 
 
 
221 aa  302  3.0000000000000004e-81  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.014564  normal  0.249814 
 
 
-
 
NC_013757  Gobs_4693  two component transcriptional regulator, winged helix family  66.82 
 
 
220 aa  281  8.000000000000001e-75  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_1330  response regulator receiver  59.91 
 
 
219 aa  254  9e-67  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_2802  two component transcriptional regulator, winged helix family  65.44 
 
 
220 aa  253  2.0000000000000002e-66  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.232869  normal 
 
 
-
 
NC_014210  Ndas_4793  two component transcriptional regulator, winged helix family  60.37 
 
 
219 aa  248  5e-65  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal  0.732153 
 
 
-
 
NC_007413  Ava_2440  two component transcriptional regulator  54.09 
 
 
222 aa  239  2e-62  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0936231  normal 
 
 
-
 
NC_011884  Cyan7425_1566  two component transcriptional regulator, winged helix family  54.5 
 
 
228 aa  239  2.9999999999999997e-62  Cyanothece sp. PCC 7425  Bacteria  normal  hitchhiker  0.00435599 
 
 
-
 
NC_013441  Gbro_4258  response regulator receiver  56.62 
 
 
220 aa  238  4e-62  Gordonia bronchialis DSM 43247  Bacteria  normal  0.0567705  n/a   
 
 
-
 
NC_012669  Bcav_3167  two component transcriptional regulator, winged helix family  63.3 
 
 
218 aa  238  5.999999999999999e-62  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.436774  normal  0.0676898 
 
 
-
 
NC_009921  Franean1_5704  two component transcriptional regulator  64.19 
 
 
220 aa  237  1e-61  Frankia sp. EAN1pec  Bacteria  normal  0.0158381  normal 
 
 
-
 
NC_014151  Cfla_2685  two component transcriptional regulator, winged helix family  60.73 
 
 
224 aa  220  9.999999999999999e-57  Cellulomonas flavigena DSM 20109  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_2006  response regulator receiver  57.92 
 
 
223 aa  220  9.999999999999999e-57  Nocardioides sp. JS614  Bacteria  normal  0.379718  n/a   
 
 
-
 
NC_013172  Bfae_02960  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  50.9 
 
 
229 aa  210  2e-53  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_21520  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  50.68 
 
 
222 aa  209  2e-53  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0794896  hitchhiker  0.0000630157 
 
 
-
 
NC_013093  Amir_4935  two component transcriptional regulator, winged helix family  59.36 
 
 
221 aa  209  3e-53  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_2344  two component transcriptional regulator, winged helix family  54.02 
 
 
227 aa  208  4e-53  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_3524  two component transcriptional regulator, winged helix family  47.73 
 
 
223 aa  202  2e-51  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_2593  two component transcriptional regulator, winged helix family  47.73 
 
 
223 aa  202  2e-51  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_2290  two component transcriptional regulator  47.75 
 
 
224 aa  197  9e-50  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_4549  two component transcriptional regulator, winged helix family  51.16 
 
 
221 aa  196  2.0000000000000003e-49  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.703481  normal 
 
 
-
 
NC_009767  Rcas_2487  two component transcriptional regulator  47.75 
 
 
224 aa  195  4.0000000000000005e-49  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.431556  normal 
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  47.75 
 
 
225 aa  192  3e-48  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_013947  Snas_4900  two component transcriptional regulator, winged helix family  50.23 
 
 
221 aa  191  7e-48  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.196174  normal 
 
 
-
 
NC_013739  Cwoe_0293  two component transcriptional regulator, winged helix family  48.17 
 
 
226 aa  189  2e-47  Conexibacter woesei DSM 14684  Bacteria  normal  0.591061  normal  0.658536 
 
 
-
 
NC_011886  Achl_2869  two component transcriptional regulator, winged helix family  50.23 
 
 
232 aa  188  5e-47  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  45 
 
 
236 aa  182  4.0000000000000006e-45  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_007413  Ava_0615  two component transcriptional regulator  45.05 
 
 
228 aa  179  4e-44  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0841359  normal  0.719107 
 
 
-
 
NC_014248  Aazo_0389  winged helix family two component transcriptional regulator  43.24 
 
 
224 aa  177  1e-43  'Nostoc azollae' 0708  Bacteria  normal  0.667669  n/a   
 
 
-
 
NC_010001  Cphy_0015  two component transcriptional regulator  41.7 
 
 
228 aa  176  3e-43  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  41.55 
 
 
224 aa  174  9.999999999999999e-43  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_008148  Rxyl_0187  two component transcriptional regulator  48.64 
 
 
227 aa  174  9.999999999999999e-43  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  42.99 
 
 
228 aa  173  1.9999999999999998e-42  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_3411  two component transcriptional regulator, winged helix family  45.05 
 
 
224 aa  172  2.9999999999999996e-42  Cyanothece sp. PCC 7425  Bacteria  normal  0.591115  normal 
 
 
-
 
NC_008578  Acel_1595  two component transcriptional regulator  45 
 
 
227 aa  172  2.9999999999999996e-42  Acidothermus cellulolyticus 11B  Bacteria  normal  0.526383  normal  0.570373 
 
 
-
 
NC_005945  BAS2056  DNA-binding response regulator  39.64 
 
 
227 aa  170  1e-41  Bacillus anthracis str. Sterne  Bacteria  normal  0.413172  n/a   
 
 
-
 
NC_007530  GBAA_2212  DNA-binding response regulator  39.64 
 
 
227 aa  170  1e-41  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_2240  DNA-binding response regulator  39.64 
 
 
227 aa  170  1e-41  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  2.85177e-28 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  44.29 
 
 
223 aa  170  2e-41  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  44.5 
 
 
235 aa  170  2e-41  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_011725  BCB4264_A2194  DNA-binding response regulator  39.64 
 
 
227 aa  170  2e-41  Bacillus cereus B4264  Bacteria  hitchhiker  0.00702475  n/a   
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  42.08 
 
 
225 aa  169  3e-41  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  43.18 
 
 
228 aa  168  5e-41  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  42.27 
 
 
227 aa  167  1e-40  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  42.73 
 
 
226 aa  167  1e-40  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  42.08 
 
 
225 aa  166  2e-40  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  43.38 
 
 
225 aa  166  2e-40  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  42.08 
 
 
225 aa  166  2e-40  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  42.08 
 
 
225 aa  166  2e-40  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_008752  Aave_3002  two component transcriptional regulator  41.63 
 
 
230 aa  166  2e-40  Acidovorax citrulli AAC00-1  Bacteria  normal  0.67465  normal  0.369251 
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  42.53 
 
 
232 aa  166  2.9999999999999998e-40  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  44.55 
 
 
227 aa  166  2.9999999999999998e-40  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  39.09 
 
 
238 aa  166  2.9999999999999998e-40  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_011138  MADE_03339  Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain  39.82 
 
 
226 aa  166  4e-40  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  38.91 
 
 
224 aa  166  4e-40  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_013131  Caci_0835  two component transcriptional regulator, winged helix family  41.44 
 
 
222 aa  164  8e-40  Catenulispora acidiphila DSM 44928  Bacteria  normal  hitchhiker  0.0000000540746 
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  44.09 
 
 
227 aa  164  8e-40  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_013525  Tter_1098  two component transcriptional regulator, winged helix family  44.04 
 
 
228 aa  164  9e-40  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_010681  Bphyt_3267  two component transcriptional regulator, winged helix family  44.6 
 
 
220 aa  164  1.0000000000000001e-39  Burkholderia phytofirmans PsJN  Bacteria  normal  0.387524  normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  43.18 
 
 
226 aa  164  1.0000000000000001e-39  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  43.12 
 
 
283 aa  164  1.0000000000000001e-39  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_007951  Bxe_A0699  two component transcriptional regulator  45.07 
 
 
220 aa  164  1.0000000000000001e-39  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  41.18 
 
 
225 aa  163  2.0000000000000002e-39  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_010070  Bmul_6295  two component heavy metal response transcriptional regulator  41.1 
 
 
223 aa  163  2.0000000000000002e-39  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.803537  normal  0.219108 
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  45 
 
 
242 aa  163  2.0000000000000002e-39  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  43.18 
 
 
226 aa  163  2.0000000000000002e-39  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  41.1 
 
 
223 aa  163  2.0000000000000002e-39  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  41.1 
 
 
223 aa  163  2.0000000000000002e-39  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  41.1 
 
 
223 aa  163  2.0000000000000002e-39  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0707  winged helix family two component transcriptional regulator  40.09 
 
 
222 aa  162  3e-39  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_007333  Tfu_2549  response regulator receiver  40.09 
 
 
222 aa  162  3e-39  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  40.27 
 
 
224 aa  162  3e-39  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_1333  response regulator receiver protein  40.09 
 
 
222 aa  162  3e-39  Streptosporangium roseum DSM 43021  Bacteria  normal  0.40527  normal  0.1595 
 
 
-
 
NC_013522  Taci_0717  two component transcriptional regulator, winged helix family  39.45 
 
 
226 aa  162  3e-39  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  hitchhiker  0.000154116  n/a   
 
 
-
 
NC_013739  Cwoe_4710  two component transcriptional regulator, winged helix family  47.71 
 
 
224 aa  162  4.0000000000000004e-39  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_10613  two component system DNA binding transcriptional regulatory protein tcrA  42.2 
 
 
253 aa  162  4.0000000000000004e-39  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.0000000499525  normal  0.750249 
 
 
-
 
NC_009511  Swit_4798  two component transcriptional regulator  41.89 
 
 
230 aa  162  4.0000000000000004e-39  Sphingomonas wittichii RW1  Bacteria  normal  normal  0.358461 
 
 
-
 
NC_008527  LACR_1701  DNA-binding response regulator  41.82 
 
 
230 aa  162  4.0000000000000004e-39  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.00672994  n/a   
 
 
-
 
NC_011830  Dhaf_2231  two component transcriptional regulator, winged helix family  43.58 
 
 
226 aa  162  5.0000000000000005e-39  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0523  two component transcriptional regulator, winged helix family  40.72 
 
 
224 aa  162  5.0000000000000005e-39  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  39.37 
 
 
224 aa  161  6e-39  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  42.73 
 
 
226 aa  161  6e-39  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_009511  Swit_3444  two component transcriptional regulator  39.35 
 
 
220 aa  161  6e-39  Sphingomonas wittichii RW1  Bacteria  normal  0.112849  normal  0.384843 
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  38.07 
 
 
222 aa  161  6e-39  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  41.1 
 
 
223 aa  161  6e-39  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_4122  two component transcriptional regulator, winged helix family  38.74 
 
 
223 aa  161  6e-39  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  40.91 
 
 
228 aa  161  7e-39  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  40.91 
 
 
228 aa  161  7e-39  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010725  Mpop_4595  two component transcriptional regulator, winged helix family  43.66 
 
 
224 aa  161  8.000000000000001e-39  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  43.64 
 
 
227 aa  161  9e-39  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  39.27 
 
 
223 aa  160  1e-38  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  40.45 
 
 
228 aa  160  1e-38  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_007643  Rru_A3187  two component transcriptional regulator  43.06 
 
 
229 aa  160  1e-38  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  38.57 
 
 
224 aa  160  1e-38  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  41.1 
 
 
223 aa  160  1e-38  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_3846  two component transcriptional regulator, winged helix family  40.54 
 
 
222 aa  160  1e-38  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_1884  two component transcriptional regulator  43.66 
 
 
222 aa  159  2e-38  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.0239131 
 
 
-
 
NC_009972  Haur_4156  two component transcriptional regulator  43.1 
 
 
232 aa  160  2e-38  Herpetosiphon aurantiacus ATCC 23779  Bacteria  decreased coverage  0.0000307056  n/a   
 
 
-
 
NC_007794  Saro_2066  two component transcriptional regulator  38.89 
 
 
225 aa  159  2e-38  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  n/a   
 
 
-
 
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