More than 300 homologs were found in PanDaTox collection
for query gene Amir_4935 on replicon NC_013093
Organism: Actinosynnema mirum DSM 43827



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013093  Amir_4935  two component transcriptional regulator, winged helix family  100 
 
 
221 aa  427  1e-119  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4793  two component transcriptional regulator, winged helix family  73.61 
 
 
219 aa  305  3e-82  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal  0.732153 
 
 
-
 
NC_007333  Tfu_1330  response regulator receiver  72.69 
 
 
219 aa  302  2.0000000000000002e-81  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_013159  Svir_31270  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  71.69 
 
 
221 aa  299  3e-80  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.014564  normal  0.249814 
 
 
-
 
NC_013757  Gobs_4693  two component transcriptional regulator, winged helix family  68.06 
 
 
220 aa  273  2.0000000000000002e-72  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_4258  response regulator receiver  66.06 
 
 
220 aa  268  2.9999999999999997e-71  Gordonia bronchialis DSM 43247  Bacteria  normal  0.0567705  n/a   
 
 
-
 
NC_009921  Franean1_5704  two component transcriptional regulator  66.52 
 
 
220 aa  253  2.0000000000000002e-66  Frankia sp. EAN1pec  Bacteria  normal  0.0158381  normal 
 
 
-
 
NC_009664  Krad_2802  two component transcriptional regulator, winged helix family  67.13 
 
 
220 aa  247  1e-64  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.232869  normal 
 
 
-
 
NC_011884  Cyan7425_1566  two component transcriptional regulator, winged helix family  58.45 
 
 
228 aa  246  2e-64  Cyanothece sp. PCC 7425  Bacteria  normal  hitchhiker  0.00435599 
 
 
-
 
NC_007413  Ava_2440  two component transcriptional regulator  57.34 
 
 
222 aa  245  4e-64  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0936231  normal 
 
 
-
 
NC_012669  Bcav_3167  two component transcriptional regulator, winged helix family  66.67 
 
 
218 aa  243  9.999999999999999e-64  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.436774  normal  0.0676898 
 
 
-
 
NC_013169  Ksed_21520  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  57.47 
 
 
222 aa  242  3.9999999999999997e-63  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0794896  hitchhiker  0.0000630157 
 
 
-
 
NC_013161  Cyan8802_2593  two component transcriptional regulator, winged helix family  55.16 
 
 
223 aa  239  2e-62  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_2006  response regulator receiver  59.01 
 
 
223 aa  239  2.9999999999999997e-62  Nocardioides sp. JS614  Bacteria  normal  0.379718  n/a   
 
 
-
 
NC_008726  Mvan_2389  two component transcriptional regulator  59.36 
 
 
219 aa  239  2.9999999999999997e-62  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.753035  normal  0.0318145 
 
 
-
 
NC_009338  Mflv_3998  two component transcriptional regulator  58.18 
 
 
220 aa  238  4e-62  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.278973  normal  0.137181 
 
 
-
 
NC_011726  PCC8801_3524  two component transcriptional regulator, winged helix family  55.36 
 
 
223 aa  237  1e-61  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013947  Snas_4900  two component transcriptional regulator, winged helix family  60.83 
 
 
221 aa  219  3e-56  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.196174  normal 
 
 
-
 
NC_014151  Cfla_2685  two component transcriptional regulator, winged helix family  64.06 
 
 
224 aa  216  2e-55  Cellulomonas flavigena DSM 20109  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_2869  two component transcriptional regulator, winged helix family  55.5 
 
 
232 aa  215  4e-55  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_014210  Ndas_4549  two component transcriptional regulator, winged helix family  55.25 
 
 
221 aa  213  2.9999999999999995e-54  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.703481  normal 
 
 
-
 
NC_013172  Bfae_02960  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  52.91 
 
 
229 aa  210  1e-53  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0187  two component transcriptional regulator  55.41 
 
 
227 aa  205  3e-52  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  50.45 
 
 
225 aa  204  1e-51  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_013174  Jden_2344  two component transcriptional regulator, winged helix family  57.21 
 
 
227 aa  203  2e-51  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  47.95 
 
 
224 aa  196  3e-49  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  47.49 
 
 
224 aa  193  2e-48  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  47.03 
 
 
224 aa  192  3e-48  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  50.23 
 
 
227 aa  192  4e-48  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  43.89 
 
 
224 aa  191  5e-48  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  45.66 
 
 
224 aa  191  6e-48  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  49.77 
 
 
227 aa  191  7e-48  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  50 
 
 
227 aa  191  7e-48  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  44.5 
 
 
225 aa  190  1e-47  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_2290  two component transcriptional regulator  49.09 
 
 
224 aa  189  2e-47  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_010571  Oter_1727  two component transcriptional regulator  47.06 
 
 
228 aa  189  2e-47  Opitutus terrae PB90-1  Bacteria  normal  0.284746  normal 
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  50.45 
 
 
236 aa  189  2.9999999999999997e-47  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  47.03 
 
 
224 aa  189  2.9999999999999997e-47  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_011830  Dhaf_2231  two component transcriptional regulator, winged helix family  51.15 
 
 
226 aa  189  4e-47  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_2487  two component transcriptional regulator  49.55 
 
 
224 aa  188  5e-47  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.431556  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  46.61 
 
 
228 aa  187  1e-46  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  51.14 
 
 
283 aa  187  1e-46  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  47.06 
 
 
226 aa  187  1e-46  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_005945  BAS2056  DNA-binding response regulator  45 
 
 
227 aa  186  2e-46  Bacillus anthracis str. Sterne  Bacteria  normal  0.413172  n/a   
 
 
-
 
NC_011773  BCAH820_2240  DNA-binding response regulator  45 
 
 
227 aa  186  2e-46  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  2.85177e-28 
 
 
-
 
NC_011138  MADE_03339  Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain  43.84 
 
 
226 aa  186  2e-46  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  49.77 
 
 
242 aa  186  2e-46  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  45.7 
 
 
226 aa  186  2e-46  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_007530  GBAA_2212  DNA-binding response regulator  45 
 
 
227 aa  186  2e-46  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  49.1 
 
 
226 aa  186  2e-46  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  47.73 
 
 
240 aa  186  4e-46  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  49.1 
 
 
226 aa  185  4e-46  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  44.24 
 
 
222 aa  184  7e-46  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_3267  two component transcriptional regulator, winged helix family  50.47 
 
 
220 aa  184  7e-46  Burkholderia phytofirmans PsJN  Bacteria  normal  0.387524  normal 
 
 
-
 
NC_011725  BCB4264_A2194  DNA-binding response regulator  45 
 
 
227 aa  184  9e-46  Bacillus cereus B4264  Bacteria  hitchhiker  0.00702475  n/a   
 
 
-
 
NC_009997  Sbal195_0632  two component transcriptional regulator  42.79 
 
 
227 aa  184  1.0000000000000001e-45  Shewanella baltica OS195  Bacteria  normal  0.157641  normal 
 
 
-
 
NC_007514  Cag_0440  two component transcriptional regulator  44.5 
 
 
225 aa  183  1.0000000000000001e-45  Chlorobium chlorochromatii CaD3  Bacteria  normal  0.747409  n/a   
 
 
-
 
NC_009665  Shew185_0604  two component transcriptional regulator  42.79 
 
 
227 aa  184  1.0000000000000001e-45  Shewanella baltica OS185  Bacteria  decreased coverage  0.00704602  n/a   
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  46.15 
 
 
225 aa  183  2.0000000000000003e-45  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  46.15 
 
 
225 aa  183  2.0000000000000003e-45  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  46.15 
 
 
225 aa  183  2.0000000000000003e-45  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_009802  CCC13826_1969  response regulator receiver domain-containing protein  41.4 
 
 
219 aa  183  2.0000000000000003e-45  Campylobacter concisus 13826  Bacteria  normal  0.478098  n/a   
 
 
-
 
NC_007951  Bxe_A0699  two component transcriptional regulator  49.53 
 
 
220 aa  182  3e-45  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  42.66 
 
 
224 aa  182  3e-45  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  46.15 
 
 
226 aa  182  4.0000000000000006e-45  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  43.05 
 
 
223 aa  182  4.0000000000000006e-45  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  42.2 
 
 
224 aa  182  5.0000000000000004e-45  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013037  Dfer_0274  two component transcriptional regulator, winged helix family  42.53 
 
 
232 aa  181  6e-45  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.701823  normal  0.83989 
 
 
-
 
NC_013216  Dtox_3055  two component transcriptional regulator, winged helix family  44.89 
 
 
227 aa  181  7e-45  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.703147  hitchhiker  0.000223036 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  44.34 
 
 
224 aa  181  7e-45  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  42.66 
 
 
224 aa  181  8.000000000000001e-45  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  47.98 
 
 
225 aa  181  8.000000000000001e-45  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_009511  Swit_4798  two component transcriptional regulator  46.61 
 
 
230 aa  181  8.000000000000001e-45  Sphingomonas wittichii RW1  Bacteria  normal  normal  0.358461 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  46.19 
 
 
225 aa  181  9.000000000000001e-45  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  46.15 
 
 
226 aa  181  1e-44  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  46.15 
 
 
226 aa  180  2e-44  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_007413  Ava_0615  two component transcriptional regulator  47.06 
 
 
228 aa  179  2e-44  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0841359  normal  0.719107 
 
 
-
 
NC_007413  Ava_3453  two component transcriptional regulator  44 
 
 
224 aa  180  2e-44  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_007512  Plut_1212  two component transcriptional regulator  47.25 
 
 
232 aa  180  2e-44  Chlorobium luteolum DSM 273  Bacteria  normal  0.0899901  normal  0.616229 
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  41.44 
 
 
238 aa  180  2e-44  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  47.49 
 
 
223 aa  179  2e-44  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  46.85 
 
 
227 aa  179  2e-44  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  47.49 
 
 
223 aa  180  2e-44  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  47.98 
 
 
225 aa  180  2e-44  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  47.49 
 
 
223 aa  180  2e-44  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  44.95 
 
 
223 aa  179  2e-44  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_013525  Tter_1435  two component transcriptional regulator, winged helix family  47.09 
 
 
233 aa  179  2.9999999999999997e-44  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  44.59 
 
 
225 aa  179  2.9999999999999997e-44  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  41.74 
 
 
224 aa  179  2.9999999999999997e-44  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_014248  Aazo_2223  winged helix family two component transcriptional regulator  45.45 
 
 
229 aa  179  2.9999999999999997e-44  'Nostoc azollae' 0708  Bacteria  normal  0.335669  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  46.19 
 
 
228 aa  179  4e-44  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_3265  two component transcriptional regulator, winged helix family  46.58 
 
 
245 aa  179  4e-44  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.45002  normal 
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  45.25 
 
 
225 aa  178  4.999999999999999e-44  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_013739  Cwoe_4710  two component transcriptional regulator, winged helix family  52.29 
 
 
224 aa  178  4.999999999999999e-44  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_010001  Cphy_0015  two component transcriptional regulator  45.29 
 
 
228 aa  178  7e-44  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_010831  Cphamn1_0990  two component transcriptional regulator, winged helix family  45.87 
 
 
222 aa  177  9e-44  Chlorobium phaeobacteroides BS1  Bacteria  hitchhiker  0.000957791  decreased coverage  0.0000715536 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  47.53 
 
 
223 aa  177  1e-43  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  45.95 
 
 
225 aa  176  2e-43  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  44.2 
 
 
230 aa  176  2e-43  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_007604  Synpcc7942_1873  two component transcriptional regulator  45.45 
 
 
226 aa  177  2e-43  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
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