More than 300 homologs were found in PanDaTox collection
for query gene Dshi_1074 on replicon NC_009952
Organism: Dinoroseobacter shibae DFL 12



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009952  Dshi_1074  methionine synthase I  100 
 
 
341 aa  686    Dinoroseobacter shibae DFL 12  Bacteria  normal  0.24236  normal 
 
 
-
 
NC_007802  Jann_2547  methionine synthase I  74.84 
 
 
340 aa  485  1e-136  Jannaschia sp. CCS1  Bacteria  normal  normal  0.946299 
 
 
-
 
NC_008044  TM1040_1468  methionine synthase I  73.56 
 
 
340 aa  475  1e-133  Ruegeria sp. TM1040  Bacteria  normal  0.799153  normal  0.613644 
 
 
-
 
NC_009428  Rsph17025_0709  methionine synthase I  72.62 
 
 
357 aa  452  1.0000000000000001e-126  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_009049  Rsph17029_0799  methionine synthase I  72.31 
 
 
335 aa  449  1e-125  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.640121 
 
 
-
 
NC_007493  RSP_2124  methionine synthase I  72.31 
 
 
335 aa  449  1e-125  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  n/a   
 
 
-
 
NC_008687  Pden_3952  methionine synthase I  57.33 
 
 
319 aa  337  1.9999999999999998e-91  Paracoccus denitrificans PD1222  Bacteria  normal  0.225692  normal 
 
 
-
 
NC_009636  Smed_1771  methionine synthase I  54.05 
 
 
337 aa  333  3e-90  Sinorhizobium medicae WSM419  Bacteria  normal  0.379105  normal  0.0676063 
 
 
-
 
NC_009012  Cthe_0645  methionine synthase (B12-dependent)  34.35 
 
 
804 aa  187  2e-46  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.474097  n/a   
 
 
-
 
NC_007498  Pcar_2722  methionine synthase I (cobalamin-dependent) methyltransferase subunit  36.83 
 
 
801 aa  183  3e-45  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_0238  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  38.74 
 
 
609 aa  182  5.0000000000000004e-45  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0549  methionine synthase (B12-dependent)  38.64 
 
 
804 aa  182  8.000000000000001e-45  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU2921  5-methyltetrahydrofolate-homocysteine methyltransferase, truncation  37.97 
 
 
804 aa  180  4e-44  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_3632  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  35.03 
 
 
617 aa  179  4.999999999999999e-44  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_2207  homocysteine S-methyltransferase  35.84 
 
 
800 aa  174  1.9999999999999998e-42  Desulfotomaculum reducens MI-1  Bacteria  normal  0.0270016  n/a   
 
 
-
 
NC_008609  Ppro_1413  homocysteine S-methyltransferase  37.2 
 
 
806 aa  174  2.9999999999999996e-42  Pelobacter propionicus DSM 2379  Bacteria  normal  0.0607109  n/a   
 
 
-
 
NC_009483  Gura_0489  homocysteine S-methyltransferase  35.37 
 
 
804 aa  171  2e-41  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0277  homocysteine S-methyltransferase  35.92 
 
 
811 aa  168  1e-40  Geobacter bemidjiensis Bem  Bacteria  normal  0.357222  n/a   
 
 
-
 
NC_011898  Ccel_1861  homocysteine S-methyltransferase  33 
 
 
434 aa  168  1e-40  Clostridium cellulolyticum H10  Bacteria  decreased coverage  0.00000268518  n/a   
 
 
-
 
NC_012918  GM21_0262  homocysteine S-methyltransferase  35.54 
 
 
813 aa  166  5.9999999999999996e-40  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.00180962 
 
 
-
 
NC_008346  Swol_1442  5-methyltetrahydrofolate-homocysteine methyltransferase, truncation  36.21 
 
 
839 aa  164  1.0000000000000001e-39  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.955782  n/a   
 
 
-
 
NC_011899  Hore_19590  homocysteine S-methyltransferase  36.05 
 
 
819 aa  164  2.0000000000000002e-39  Halothermothrix orenii H 168  Bacteria  normal  0.399567  n/a   
 
 
-
 
NC_010320  Teth514_1211  homocysteine S-methyltransferase  34.16 
 
 
807 aa  162  6e-39  Thermoanaerobacter sp. X514  Bacteria  normal  0.0179968  n/a   
 
 
-
 
NC_008609  Ppro_0283  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  37.86 
 
 
615 aa  162  6e-39  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_1187  homocysteine S-methyltransferase  34.47 
 
 
629 aa  160  3e-38  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009616  Tmel_0729  homocysteine S-methyltransferase  34.13 
 
 
781 aa  156  4e-37  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_009718  Fnod_0772  homocysteine S-methyltransferase  31.97 
 
 
780 aa  155  1e-36  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.0538889  n/a   
 
 
-
 
NC_012034  Athe_0324  homocysteine S-methyltransferase  32.76 
 
 
413 aa  155  1e-36  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_0073  homocysteine S-methyltransferase  34.4 
 
 
290 aa  154  2.9999999999999998e-36  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_2941  homocysteine S-methyltransferase  38.46 
 
 
801 aa  153  5e-36  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.651468  normal 
 
 
-
 
NC_010003  Pmob_1792  homocysteine S-methyltransferase  32.42 
 
 
774 aa  150  3e-35  Petrotoga mobilis SJ95  Bacteria  normal  0.709712  n/a   
 
 
-
 
NC_010718  Nther_0682  homocysteine S-methyltransferase  32.54 
 
 
793 aa  147  2.0000000000000003e-34  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_0656  homocysteine S-methyltransferase  32.99 
 
 
768 aa  146  4.0000000000000006e-34  Thermotoga petrophila RKU-1  Bacteria  normal  0.79655  n/a   
 
 
-
 
NC_010483  TRQ2_0680  homocysteine S-methyltransferase  32.99 
 
 
768 aa  145  9e-34  Thermotoga sp. RQ2  Bacteria  normal  0.412837  n/a   
 
 
-
 
NC_008148  Rxyl_0843  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  34.69 
 
 
611 aa  145  1e-33  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0613  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  36.59 
 
 
610 aa  143  4e-33  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_0627  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  35.22 
 
 
610 aa  142  7e-33  Geobacter sp. M21  Bacteria  n/a    unclonable  1.07944e-34 
 
 
-
 
NC_002939  GSU2974  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  34.06 
 
 
605 aa  142  8e-33  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_3258  homocysteine S-methyltransferase  29.79 
 
 
841 aa  140  3e-32  Clostridium phytofermentans ISDg  Bacteria  normal  0.728955  n/a   
 
 
-
 
NC_013165  Shel_23490  methionine synthase (B12-dependent)  35.05 
 
 
820 aa  140  3e-32  Slackia heliotrinireducens DSM 20476  Bacteria  normal  0.136684  hitchhiker  0.0000158862 
 
 
-
 
NC_013522  Taci_0141  homocysteine S-methyltransferase  36.86 
 
 
816 aa  139  4.999999999999999e-32  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  hitchhiker  0.0000403798  n/a   
 
 
-
 
NC_007519  Dde_2115  methionine synthase (B12-dependent)  34.55 
 
 
841 aa  139  4.999999999999999e-32  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.356238  n/a   
 
 
-
 
NC_007517  Gmet_0504  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  35.87 
 
 
605 aa  139  7e-32  Geobacter metallireducens GS-15  Bacteria  normal  0.0120544  normal 
 
 
-
 
NC_008009  Acid345_3426  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  33.45 
 
 
617 aa  138  1e-31  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.41819  normal 
 
 
-
 
NC_011769  DvMF_0476  homocysteine S-methyltransferase  33.81 
 
 
818 aa  138  1e-31  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.0411261 
 
 
-
 
NC_008751  Dvul_1548  homocysteine S-methyltransferase  37.15 
 
 
804 aa  138  1e-31  Desulfovibrio vulgaris DP4  Bacteria  normal  0.0662443  normal 
 
 
-
 
NC_009483  Gura_0708  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  34.41 
 
 
604 aa  137  2e-31  Geobacter uraniireducens Rf4  Bacteria  normal  0.537957  n/a   
 
 
-
 
NC_013440  Hoch_4784  homocysteine S-methyltransferase  34.73 
 
 
643 aa  137  2e-31  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_1947  methionine synthase  32.79 
 
 
1223 aa  137  3.0000000000000003e-31  Meiothermus silvanus DSM 9946  Bacteria  normal  0.0537124  normal  0.960844 
 
 
-
 
NC_013517  Sterm_3081  homocysteine S-methyltransferase  31.8 
 
 
791 aa  135  9.999999999999999e-31  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_013946  Mrub_1138  methionine synthase  31.92 
 
 
1215 aa  134  3e-30  Meiothermus ruber DSM 1279  Bacteria  normal  0.537288  normal  0.145457 
 
 
-
 
NC_013173  Dbac_1858  homocysteine S-methyltransferase  32.97 
 
 
803 aa  132  1.0000000000000001e-29  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_0839  homocysteine S-methyltransferase  31.6 
 
 
285 aa  130  3e-29  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_2211  methionine synthase  32.68 
 
 
1178 aa  130  3e-29  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_007513  Syncc9902_1123  5-methyltetrahydrofolate--homocysteine methyltransferase  30.77 
 
 
1208 aa  130  4.0000000000000003e-29  Synechococcus sp. CC9902  Bacteria  decreased coverage  0.00712875  n/a   
 
 
-
 
NC_007516  Syncc9605_1355  methionine synthase (B12-dependent)  30.17 
 
 
1208 aa  129  7.000000000000001e-29  Synechococcus sp. CC9605  Bacteria  normal  0.290102  normal  0.418289 
 
 
-
 
NC_009484  Acry_1700  methionine synthase  33.76 
 
 
1171 aa  128  1.0000000000000001e-28  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_2544  methionine synthase  31.7 
 
 
1180 aa  127  2.0000000000000002e-28  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.00356448  n/a   
 
 
-
 
NC_010085  Nmar_1268  homocysteine S-methyltransferase  30.82 
 
 
320 aa  125  9e-28  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  0.897971 
 
 
-
 
NC_011883  Ddes_1442  homocysteine S-methyltransferase  32.85 
 
 
802 aa  125  1e-27  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  0.195548  n/a   
 
 
-
 
NC_008312  Tery_2492  methionine synthase (B12-dependent)  29.28 
 
 
1224 aa  122  7e-27  Trichodesmium erythraeum IMS101  Bacteria  normal  0.494606  normal 
 
 
-
 
NC_011831  Cagg_0032  methionine synthase  32.08 
 
 
1196 aa  122  9.999999999999999e-27  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.392993  normal 
 
 
-
 
NC_013173  Dbac_0626  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.29 
 
 
599 aa  122  9.999999999999999e-27  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.490063  n/a   
 
 
-
 
NC_010571  Oter_4332  homocysteine S-methyltransferase  32.57 
 
 
302 aa  121  1.9999999999999998e-26  Opitutus terrae PB90-1  Bacteria  normal  0.506353  normal 
 
 
-
 
NC_010803  Clim_2062  B12-dependent methionine synthase  32.36 
 
 
1228 aa  120  1.9999999999999998e-26  Chlorobium limicola DSM 245  Bacteria  normal  0.458303  n/a   
 
 
-
 
NC_009674  Bcer98_2983  5-methyltetrahydrofolate--homocysteine methyltransferase  30.3 
 
 
1132 aa  120  3e-26  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_4250  methionine synthase  31.64 
 
 
1261 aa  120  3.9999999999999996e-26  Spirosoma linguale DSM 74  Bacteria  normal  0.49174  normal 
 
 
-
 
NC_007335  PMN2A_0333  putative methionine synthase  28.81 
 
 
1182 aa  119  7.999999999999999e-26  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0325  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.97 
 
 
605 aa  119  7.999999999999999e-26  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_3230  methionine synthase  28.96 
 
 
1183 aa  117  1.9999999999999998e-25  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_009441  Fjoh_1508  homocysteine S-methyltransferase  31.87 
 
 
334 aa  117  1.9999999999999998e-25  Flavobacterium johnsoniae UW101  Bacteria  normal  n/a   
 
 
-
 
NC_011365  Gdia_2881  methionine synthase  32.89 
 
 
1168 aa  117  3e-25  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  normal  0.0934972 
 
 
-
 
NC_005945  BAS4157  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.72 
 
 
610 aa  117  3e-25  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_3996  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.72 
 
 
610 aa  117  3e-25  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4006  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.72 
 
 
610 aa  117  3e-25  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4108  methionine synthase  29.56 
 
 
1132 aa  117  3e-25  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_007484  Noc_1206  B12-dependent methionine synthase  32.21 
 
 
1232 aa  117  3e-25  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4479  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.72 
 
 
610 aa  117  3e-25  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_013124  Afer_0723  methionine synthase  34.32 
 
 
1151 aa  117  3e-25  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.830371  n/a   
 
 
-
 
NC_011773  BCAH820_4275  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.72 
 
 
610 aa  117  3e-25  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_008819  NATL1_10061  putative methionine synthase  28.47 
 
 
1182 aa  117  3e-25  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal  0.0164665 
 
 
-
 
NC_011658  BCAH187_A4386  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.72 
 
 
610 aa  117  3e-25  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A4385  5-methyltetrahydrofolate--homocysteine methyltransferase  29.43 
 
 
1132 aa  117  3e-25  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_4333  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.56 
 
 
610 aa  117  3.9999999999999997e-25  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_014248  Aazo_1661  methionine synthase  28.03 
 
 
1176 aa  116  3.9999999999999997e-25  'Nostoc azollae' 0708  Bacteria  normal  0.158089  n/a   
 
 
-
 
NC_013889  TK90_0182  methionine synthase  31.12 
 
 
1263 aa  116  3.9999999999999997e-25  Thioalkalivibrio sp. K90mix  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B0868  methionine synthase  29.63 
 
 
1132 aa  117  3.9999999999999997e-25  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_003909  BCE_4332  5-methyltetrahydrofolate--homocysteine methyltransferase  29.43 
 
 
1132 aa  116  5e-25  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4156  5-methyltetrahydrofolate--homocysteine methyltransferase  29.97 
 
 
1132 aa  116  5e-25  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4005  5-methyltetrahydrofolate--homocysteine methyltransferase  29.97 
 
 
1133 aa  116  5e-25  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4367  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.58 
 
 
610 aa  116  5e-25  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4274  5-methyltetrahydrofolate--homocysteine methyltransferase  29.97 
 
 
1132 aa  116  5e-25  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_007530  GBAA_4478  5-methyltetrahydrofolate--homocysteine methyltransferase  29.97 
 
 
1132 aa  116  5e-25  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4366  methionine synthase  29.63 
 
 
1132 aa  116  5e-25  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_5287  methionine synthase  31.85 
 
 
1266 aa  116  6e-25  Haliangium ochraceum DSM 14365  Bacteria  normal  0.212227  normal 
 
 
-
 
NC_007577  PMT9312_0923  putative methionine synthase  27.48 
 
 
1188 aa  115  6.9999999999999995e-25  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  0.554379  n/a   
 
 
-
 
NC_011772  BCG9842_B0867  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.34 
 
 
610 aa  115  7.999999999999999e-25  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_010184  BcerKBAB4_4109  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  30.45 
 
 
610 aa  115  1.0000000000000001e-24  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_5917  methionine synthase  29.19 
 
 
1154 aa  114  2.0000000000000002e-24  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0712476  normal  0.0446229 
 
 
-
 
NC_011145  AnaeK_0092  methionine synthase  31.79 
 
 
1150 aa  114  2.0000000000000002e-24  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
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