More than 300 homologs were found in PanDaTox collection
for query gene BMA10229_0469 on replicon NC_008835
Organism: Burkholderia mallei NCTC 10229



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009075  BURPS668_A1458  DNA-binding response regulator  100 
 
 		 140 aa  215  2e-55  Burkholderia pseudomallei 668  Bacteria  normal  1  n/a   
 
 
-
 
NC_008784  BMASAVP1_0193  response regulator  100 
 
 		 108 aa  214  4e-55  Burkholderia mallei SAVP1  Bacteria  normal  0.673566  n/a   
 
 
-
 
NC_008835  BMA10229_0469  alginate biosynthesis regulatory protein  100 
 
 		 108 aa  214  4e-55  Burkholderia mallei NCTC 10229  Bacteria  normal  0.901816  n/a   
 
 
-
 
NC_007435  BURPS1710b_A2603  response regulator  100 
 
 		 243 aa  195  2.0000000000000003e-49  Burkholderia pseudomallei 1710b  Bacteria  normal  1  n/a   
 
 
-
 
NC_007650  BTH_II1400  response regulator  96.7 
 
 		 243 aa  181  3e-45  Burkholderia thailandensis E264  Bacteria  normal  1  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1373  DNA-binding response regulator  97.73 
 
 		 300 aa  176  1e-43  Burkholderia pseudomallei 1106a  Bacteria  normal  0.648551  n/a   
 
 
-
 
NC_007509  Bcep18194_C6684  LytR/AlgR family transcriptional regulator  77.32 
 
 		 243 aa  153  7e-37  Burkholderia sp. 383  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009675  Anae109_3416  putative two-component response-regulatory protein YehT  52.48 
 
 		 237 aa  101  3e-21  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.329348  normal  0.0577965 
 
 
-
 
NC_009483  Gura_2443  LytTR family two component transcriptional regulator  56.52 
 
 		 279 aa  97.1  8e-20  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011071  Smal_0421  two component transcriptional regulator, LytTR family  60.53 
 
 		 256 aa  94  6e-19  Stenotrophomonas maltophilia R551-3  Bacteria  normal  1  normal  0.268274 
 
 
-
 
NC_009784  VIBHAR_07024  transcriptional regulator  50.6 
 
 		 263 aa  89  2e-17  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_007517  Gmet_2697  LytR/AlgR family transcriptional regulator  46.08 
 
 		 240 aa  87.8  4e-17  Geobacter metallireducens GS-15  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010465  YPK_3358  putative two-component response-regulatory protein YehT  51.81 
 
 		 238 aa  88.2  4e-17  Yersinia pseudotuberculosis YPIII  Bacteria  normal  1  n/a   
 
 
-
 
NC_013457  VEA_000974  response regulator of the LytR/AlgR family  50.6 
 
 		 263 aa  87.8  4e-17  Vibrio sp. Ex25  Bacteria  normal  0.728867  n/a   
 
 
-
 
NC_007908  Rfer_2452  putative two-component response-regulatory protein YehT  42.57 
 
 		 238 aa  87.8  4e-17  Rhodoferax ferrireducens T118  Bacteria  normal  0.0310324  n/a   
 
 
-
 
NC_010159  YpAngola_A3485  putative two-component response-regulatory protein YehT  51.81 
 
 		 238 aa  88.2  4e-17  Yersinia pestis Angola  Bacteria  normal  1  normal  0.159726 
 
 
-
 
NC_009708  YpsIP31758_3221  putative two-component response-regulatory protein YehT  51.81 
 
 		 238 aa  87.8  4e-17  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  1  n/a   
 
 
-
 
NC_009457  VC0395_A0224  putative two-component response-regulatory protein YehT  43.14 
 
 		 237 aa  88.2  4e-17  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_009456  VC0395_0387  response regulator  50.53 
 
 		 261 aa  87.8  5e-17  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_010717  PXO_03033  transcriptional regulator protein  50 
 
 		 165 aa  87.4  6e-17  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009901  Spea_1479  putative two-component response-regulatory protein YehT  49.4 
 
 		 236 aa  86.3  1e-16  Shewanella pealeana ATCC 700345  Bacteria  normal  0.0100477  n/a   
 
 
-
 
NC_011830  Dhaf_0410  response regulator receiver and SARP domain protein  46.39 
 
 		 376 aa  85.1  3e-16  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00000633698  n/a   
 
 
-
 
NC_010658  SbBS512_E0865  putative two-component response-regulatory protein YehT  48.19 
 
 		 239 aa  85.1  3e-16  Shigella boydii CDC 3083-94  Bacteria  normal  1  n/a   
 
 
-
 
NC_007912  Sde_3900  response regulator receiver domain-containing protein  43.27 
 
 		 261 aa  84.3  4e-16  Saccharophagus degradans 2-40  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011830  Dhaf_0495  response regulator receiver and SARP domain protein  47.56 
 
 		 365 aa  83.6  8e-16  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00000000000108458  n/a   
 
 
-
 
NC_013037  Dfer_4386  two component transcriptional regulator, LytTR family  42.71 
 
 		 260 aa  83.2  0.000000000000001  Dyadobacter fermentans DSM 18053  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014230  CA2559_04910  two-component system response regulator  47.67 
 
 		 236 aa  83.2  0.000000000000001  Croceibacter atlanticus HTCC2559  Bacteria  normal  0.981835  n/a   
 
 
-
 
NC_007973  Rmet_1381  LytR/AlgR family transcriptional regulator  50.6 
 
 		 273 aa  83.2  0.000000000000001  Cupriavidus metallidurans CH34  Bacteria  normal  1  normal  0.557466 
 
 
-
 
NC_012912  Dd1591_0959  putative two-component response-regulatory protein YehT  48.19 
 
 		 241 aa  83.2  0.000000000000001  Dickeya zeae Ech1591  Bacteria  normal  0.606019  n/a   
 
 
-
 
NC_011312  VSAL_I1318  putative two-component response-regulatory protein YehT  50.62 
 
 		 238 aa  82.8  0.000000000000001  Aliivibrio salmonicida LFI1238  Bacteria  normal  1  n/a   
 
 
-
 
CP001509  ECD_02054  predicted response regulator in two-component system withYehU  46.99 
 
 		 239 aa  82.4  0.000000000000002  Escherichia coli BL21(DE3)  Bacteria  normal  1  n/a   
 
 
-
 
CP001637  EcDH1_1533  two component transcriptional regulator, LytTR family  46.99 
 
 		 239 aa  82.4  0.000000000000002  Escherichia coli DH1  Bacteria  normal  0.726215  n/a   
 
 
-
 
NC_011083  SeHA_C2393  putative two-component response-regulatory protein YehT  45.78 
 
 		 239 aa  82.4  0.000000000000002  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011094  SeSA_A2397  putative two-component response-regulatory protein YehT  45.78 
 
 		 239 aa  82.4  0.000000000000002  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.423362  normal  1 
 
 
-
 
NC_009800  EcHS_A2259  putative two-component response-regulatory protein YehT  46.99 
 
 		 239 aa  82.4  0.000000000000002  Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
NC_007925  RPC_1083  putative two-component response-regulatory protein YehT  46.99 
 
 		 239 aa  82.4  0.000000000000002  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.450563  normal  1 
 
 
-
 
NC_010468  EcolC_1522  putative two-component response-regulatory protein YehT  46.99 
 
 		 239 aa  82.4  0.000000000000002  Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011353  ECH74115_3112  putative two-component response-regulatory protein YehT  46.99 
 
 		 239 aa  82.4  0.000000000000002  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  0.148941 
 
 
-
 
NC_011205  SeD_A2505  putative two-component response-regulatory protein YehT  45.78 
 
 		 239 aa  82.4  0.000000000000002  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011080  SNSL254_A2348  putative two-component response-regulatory protein YehT  45.78 
 
 		 239 aa  82.4  0.000000000000002  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009801  EcE24377A_2413  putative two-component response-regulatory protein YehT  46.99 
 
 		 239 aa  82.4  0.000000000000002  Escherichia coli E24377A  Bacteria  normal  1  n/a   
 
 
-
 
NC_011149  SeAg_B2304  putative two-component response-regulatory protein YehT  45.78 
 
 		 239 aa  82.4  0.000000000000002  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  1  n/a   
 
 
-
 
NC_012892  B21_02012  hypothetical protein  46.99 
 
 		 239 aa  82.4  0.000000000000002  Escherichia coli BL21  Bacteria  normal  1  n/a   
 
 
-
 
NC_013421  Pecwa_1130  putative two-component response-regulatory protein YehT  45.98 
 
 		 238 aa  82.4  0.000000000000002  Pectobacterium wasabiae WPP163  Bacteria  normal  1  n/a   
 
 
-
 
NC_013061  Phep_3159  response regulator receiver  41.58 
 
 		 242 aa  81.6  0.000000000000003  Pedobacter heparinus DSM 2366  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009675  Anae109_1440  putative two-component response-regulatory protein YehT  54.22 
 
 		 236 aa  81.6  0.000000000000003  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010498  EcSMS35_0919  putative two-component response-regulatory protein YehT  46.99 
 
 		 239 aa  82  0.000000000000003  Escherichia coli SMS-3-5  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009656  PSPA7_6007  alginate biosynthesis regulatory protein AlgR  42.45 
 
 		 248 aa  81.3  0.000000000000004  Pseudomonas aeruginosa PA7  Bacteria  normal  0.404994  n/a   
 
 
-
 
NC_013730  Slin_3594  two component transcriptional regulator, LytTR family  46.15 
 
 		 260 aa  81.3  0.000000000000004  Spirosoma linguale DSM 74  Bacteria  normal  0.833136  normal  0.0457058 
 
 
-
 
NC_011138  MADE_01918  putative response regulator in two-component regulatory system  48.05 
 
 		 275 aa  81.3  0.000000000000004  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.159199  n/a   
 
 
-
 
NC_009436  Ent638_2723  putative two-component response-regulatory protein YehT  43.37 
 
 		 239 aa  81.3  0.000000000000004  Enterobacter sp. 638  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007005  Psyr_0063  response regulator receiver:LytTr DNA-binding region  47.62 
 
 		 248 aa  80.9  0.000000000000005  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010506  Swoo_1765  putative two-component response-regulatory protein YehT  45.78 
 
 		 232 aa  80.9  0.000000000000005  Shewanella woodyi ATCC 51908  Bacteria  normal  0.199181  hitchhiker  0.00544661 
 
 
-
 
NC_012917  PC1_3149  putative two-component response-regulatory protein YehT  47.62 
 
 		 238 aa  80.9  0.000000000000005  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007347  Reut_A1965  response regulator receiver:LytTr DNA-binding region  51.81 
 
 		 273 aa  80.9  0.000000000000006  Ralstonia eutropha JMP134  Bacteria  normal  0.864475  n/a   
 
 
-
 
NC_004578  PSPTO_0127  alginate biosynthesis regulatory protein AlgR  47.62 
 
 		 248 aa  80.5  0.000000000000007  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  1  n/a   
 
 
-
 
NC_008463  PA14_69470  alginate biosynthesis regulatory protein AlgR  41.51 
 
 		 248 aa  80.5  0.000000000000007  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.184834  normal  1 
 
 
-
 
NC_009832  Spro_3405  LytTR family two component transcriptional regulator  39.05 
 
 		 244 aa  80.1  0.000000000000009  Serratia proteamaculans 568  Bacteria  normal  0.732179  normal  1 
 
 
-
 
NC_013132  Cpin_5734  two component transcriptional regulator, LytTR family  49.38 
 
 		 257 aa  80.1  0.000000000000009  Chitinophaga pinensis DSM 2588  Bacteria  normal  1  normal  1 
 
 
-
 
NC_003910  CPS_1819  LytTr DNA-binding response regulator  37.38 
 
 		 260 aa  79.7  0.00000000000001  Colwellia psychrerythraea 34H  Bacteria  normal  0.148301  n/a   
 
 
-
 
NC_011901  Tgr7_0031  response regulator receiver protein  44.23 
 
 		 243 aa  79.7  0.00000000000001  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  1  n/a   
 
 
-
 
NC_009654  Mmwyl1_3341  putative two-component response-regulatory protein YehT  45.68 
 
 		 244 aa  79.7  0.00000000000001  Marinomonas sp. MWYL1  Bacteria  normal  1  normal  0.798853 
 
 
-
 
NC_013037  Dfer_5142  two component transcriptional regulator, LytTR family  40 
 
 		 244 aa  79.3  0.00000000000001  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.546377  normal  1 
 
 
-
 
NC_013385  Adeg_1761  two component transcriptional regulator, LytTR family  39.6 
 
 		 251 aa  79.3  0.00000000000002  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_0497  response regulator receiver and SARP domain protein  45.68 
 
 		 363 aa  79  0.00000000000002  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.0000475999  n/a   
 
 
-
 
NC_003910  CPS_2278  LytTr DNA-binding response regulator  47.06 
 
 		 280 aa  78.6  0.00000000000002  Colwellia psychrerythraea 34H  Bacteria  normal  0.421967  n/a   
 
 
-
 
NC_011663  Sbal223_0059  two component transcriptional regulator, LytTR family  38.46 
 
 		 243 aa  78.6  0.00000000000002  Shewanella baltica OS223  Bacteria  normal  0.182784  normal  1 
 
 
-
 
NC_009783  VIBHAR_00984  putative two-component response-regulatory protein YehT  46.99 
 
 		 242 aa  79.3  0.00000000000002  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_012880  Dd703_0957  putative two-component response-regulatory protein YehT  45.78 
 
 		 241 aa  79.3  0.00000000000002  Dickeya dadantii Ech703  Bacteria  normal  0.147856  n/a   
 
 
-
 
NC_010682  Rpic_1227  two component transcriptional regulator, LytTR family  51.9 
 
 		 277 aa  79  0.00000000000002  Ralstonia pickettii 12J  Bacteria  normal  0.299238  normal  0.813842 
 
 
-
 
NC_013456  VEA_004414  response regulator of the LytR/AlgR family  46.99 
 
 		 242 aa  79  0.00000000000002  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_009831  Ssed_2883  putative two-component response-regulatory protein YehT  42.86 
 
 		 236 aa  79  0.00000000000002  Shewanella sediminis HAW-EB3  Bacteria  unclonable  0.0000000903631  unclonable  0.0000000000401288 
 
 
-
 
NC_011830  Dhaf_1568  response regulator receiver and SARP domain protein  42.11 
 
 		 288 aa  79  0.00000000000002  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0553389  n/a   
 
 
-
 
NC_007298  Daro_2093  putative two-component response-regulatory protein YehT  44.55 
 
 		 237 aa  78.6  0.00000000000003  Dechloromonas aromatica RCB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009665  Shew185_0055  LytTR family two component transcriptional regulator  38.46 
 
 		 243 aa  78.6  0.00000000000003  Shewanella baltica OS185  Bacteria  normal  0.868518  n/a   
 
 
-
 
NC_012880  Dd703_2357  two component transcriptional regulator, LytTR family  39.39 
 
 		 244 aa  78.6  0.00000000000003  Dickeya dadantii Ech703  Bacteria  normal  1  n/a   
 
 
-
 
NC_009997  Sbal195_0060  LytTR family two component transcriptional regulator  38.46 
 
 		 243 aa  78.2  0.00000000000003  Shewanella baltica OS195  Bacteria  normal  0.0478076  hitchhiker  0.000497336 
 
 
-
 
NC_009052  Sbal_4299  LytTR family two component transcriptional regulator  38.46 
 
 		 243 aa  78.2  0.00000000000003  Shewanella baltica OS155  Bacteria  decreased coverage  0.000001386  n/a   
 
 
-
 
NC_013216  Dtox_1869  two component transcriptional regulator, LytTR family  43.68 
 
 		 243 aa  78.2  0.00000000000004  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000208305  normal  0.145854 
 
 
-
 
NC_009092  Shew_2329  putative two-component response-regulatory protein YehT  46.99 
 
 		 236 aa  77.8  0.00000000000004  Shewanella loihica PV-4  Bacteria  normal  0.0108361  normal  0.9097 
 
 
-
 
NC_010571  Oter_2329  LytTR family two component transcriptional regulator  53.33 
 
 		 255 aa  78.2  0.00000000000004  Opitutus terrae PB90-1  Bacteria  normal  0.0531557  decreased coverage  0.00207881 
 
 
-
 
NC_013216  Dtox_3773  two component transcriptional regulator, LytTR family  45.88 
 
 		 260 aa  77.4  0.00000000000005  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.10961  normal  1 
 
 
-
 
NC_013501  Rmar_2186  two component transcriptional regulator, LytTR family  48.19 
 
 		 275 aa  77.8  0.00000000000005  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_013132  Cpin_6586  two component transcriptional regulator, LytTR family  44.87 
 
 		 246 aa  77.4  0.00000000000005  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.318104  normal  1 
 
 
-
 
NC_011830  Dhaf_1614  response regulator receiver and SARP domain protein  54.93 
 
 		 376 aa  77.4  0.00000000000006  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.401218  n/a   
 
 
-
 
NC_008700  Sama_1281  putative two-component response-regulatory protein YehT  49.4 
 
 		 236 aa  77.4  0.00000000000006  Shewanella amazonensis SB2B  Bacteria  normal  0.155887  normal  0.0159688 
 
 
-
 
NC_013730  Slin_4710  two component transcriptional regulator, LytTR family  39.8 
 
 		 254 aa  77.4  0.00000000000006  Spirosoma linguale DSM 74  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007644  Moth_2172  LytR/AlgR family transcriptional regulator  40.37 
 
 		 252 aa  77  0.00000000000008  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.0721488  normal  0.0255714 
 
 
-
 
NC_009997  Sbal195_1695  putative two-component response-regulatory protein YehT  45.24 
 
 		 236 aa  76.6  0.00000000000009  Shewanella baltica OS195  Bacteria  decreased coverage  0.00000884824  normal  1 
 
 
-
 
NC_008321  Shewmr4_0057  response regulator receiver protein  37.5 
 
 		 243 aa  76.6  0.00000000000009  Shewanella sp. MR-4  Bacteria  decreased coverage  0.0000048418  decreased coverage  0.0000000648872 
 
 
-
 
NC_008322  Shewmr7_0055  response regulator receiver protein  37.5 
 
 		 243 aa  76.6  0.00000000000009  Shewanella sp. MR-7  Bacteria  decreased coverage  0.0000989316  hitchhiker  0.000468323 
 
 
-
 
NC_008345  Sfri_2434  putative two-component response-regulatory protein YehT  44.32 
 
 		 236 aa  76.6  0.00000000000009  Shewanella frigidimarina NCIMB 400  Bacteria  normal  0.318628  n/a   
 
 
-
 
NC_011663  Sbal223_2685  putative two-component response-regulatory protein YehT  45.24 
 
 		 236 aa  76.6  0.00000000000009  Shewanella baltica OS223  Bacteria  normal  0.0538398  hitchhiker  0.000367908 
 
 
-
 
NC_009052  Sbal_1673  putative two-component response-regulatory protein YehT  45.24 
 
 		 236 aa  76.6  0.00000000000009  Shewanella baltica OS155  Bacteria  hitchhiker  0.00000537167  n/a   
 
 
-
 
NC_009665  Shew185_1658  putative two-component response-regulatory protein YehT  45.24 
 
 		 236 aa  76.6  0.00000000000009  Shewanella baltica OS185  Bacteria  hitchhiker  0.00000000153786  n/a   
 
 
-
 
NC_012856  Rpic12D_1290  two component transcriptional regulator, LytTR family  51.9 
 
 		 277 aa  76.6  0.0000000000001  Ralstonia pickettii 12D  Bacteria  normal  1  normal  0.212023 
 
 
-
 
NC_013131  Caci_0068  two component transcriptional regulator, LytTR family  46.24 
 
 		 244 aa  76.6  0.0000000000001  Catenulispora acidiphila DSM 44928  Bacteria  decreased coverage  0.00288448  normal  1 
 
 
-
 
NC_009439  Pmen_0279  two-component response regulator AlgR  44.05 
 
 		 248 aa  76.3  0.0000000000001  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008009  Acid345_3487  LytR/AlgR family transcriptional regulator  40.82 
 
 		 253 aa  75.9  0.0000000000002  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.76921  normal  1 
 
 
-
 
NC_013441  Gbro_0699  response regulator receiver  42.71 
 
 		 275 aa  75.9  0.0000000000002  Gordonia bronchialis DSM 43247  Bacteria  normal  1  n/a   
 
 
-
 
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