More than 300 homologs were found in PanDaTox collection
for query gene Aaci_2268 on replicon NC_013205
Organism: Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013205  Aaci_2268  two component transcriptional regulator, winged helix family  100 
 
 
221 aa  437  9.999999999999999e-123  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0523  two component transcriptional regulator, winged helix family  53.21 
 
 
224 aa  218  5e-56  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009513  Lreu_1228  two component transcriptional regulator  49.1 
 
 
228 aa  212  3.9999999999999995e-54  Lactobacillus reuteri DSM 20016  Bacteria  hitchhiker  0.00000325236  n/a   
 
 
-
 
NC_003909  BCE_2675  DNA-binding response regulator  47.03 
 
 
224 aa  211  7e-54  Bacillus cereus ATCC 10987  Bacteria  normal  0.0180828  n/a   
 
 
-
 
NC_010001  Cphy_0015  two component transcriptional regulator  49.09 
 
 
228 aa  211  7.999999999999999e-54  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_2492  two component transcriptional regulator  46.58 
 
 
224 aa  208  6e-53  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.22217  n/a   
 
 
-
 
NC_011725  BCB4264_A2673  DNA-binding response regulator  46.58 
 
 
224 aa  207  7e-53  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_2231  two component transcriptional regulator, winged helix family  50.91 
 
 
226 aa  201  6e-51  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_1701  DNA-binding response regulator  48.87 
 
 
230 aa  201  7e-51  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.00672994  n/a   
 
 
-
 
NC_009767  Rcas_2487  two component transcriptional regulator  49.77 
 
 
224 aa  199  3e-50  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.431556  normal 
 
 
-
 
NC_009523  RoseRS_2290  two component transcriptional regulator  49.32 
 
 
224 aa  197  7e-50  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009487  SaurJH9_1476  two component transcriptional regulator  47.06 
 
 
219 aa  197  1.0000000000000001e-49  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1505  response regulator receiver  47.06 
 
 
219 aa  197  1.0000000000000001e-49  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.404603  n/a   
 
 
-
 
NC_008530  LGAS_1398  DNA-binding response regulator  45.06 
 
 
246 aa  196  2.0000000000000003e-49  Lactobacillus gasseri ATCC 33323  Bacteria  hitchhiker  0.00000000000136334  hitchhiker  8.832960000000001e-24 
 
 
-
 
NC_008531  LEUM_1732  DNA-binding response regulator  47.53 
 
 
229 aa  196  2.0000000000000003e-49  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.019008  n/a   
 
 
-
 
NC_013517  Sterm_2324  two component transcriptional regulator, winged helix family  43.58 
 
 
223 aa  196  3e-49  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.237639  n/a   
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  46.33 
 
 
224 aa  195  5.000000000000001e-49  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  45.54 
 
 
224 aa  194  9e-49  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  45.25 
 
 
227 aa  194  1e-48  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  45.09 
 
 
224 aa  192  2e-48  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_011884  Cyan7425_3411  two component transcriptional regulator, winged helix family  49.77 
 
 
224 aa  192  2e-48  Cyanothece sp. PCC 7425  Bacteria  normal  0.591115  normal 
 
 
-
 
NC_010803  Clim_1291  two component transcriptional regulator, winged helix family  46.54 
 
 
222 aa  193  2e-48  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_0615  two component transcriptional regulator  47.95 
 
 
228 aa  192  4e-48  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0841359  normal  0.719107 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  45.09 
 
 
224 aa  191  6e-48  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011126  HY04AAS1_1151  two component transcriptional regulator, winged helix family  41.26 
 
 
225 aa  191  7e-48  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  n/a   
 
 
-
 
NC_007512  Plut_1212  two component transcriptional regulator  46.19 
 
 
232 aa  191  8e-48  Chlorobium luteolum DSM 273  Bacteria  normal  0.0899901  normal  0.616229 
 
 
-
 
NC_007514  Cag_0440  two component transcriptional regulator  46.08 
 
 
225 aa  191  8e-48  Chlorobium chlorochromatii CaD3  Bacteria  normal  0.747409  n/a   
 
 
-
 
NC_004116  SAG1625  DNA-binding response regulator CsrR  48.42 
 
 
229 aa  189  2.9999999999999997e-47  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.137799  n/a   
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  44.2 
 
 
224 aa  189  2.9999999999999997e-47  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_010831  Cphamn1_0990  two component transcriptional regulator, winged helix family  46.54 
 
 
222 aa  189  4e-47  Chlorobium phaeobacteroides BS1  Bacteria  hitchhiker  0.000957791  decreased coverage  0.0000715536 
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  47.95 
 
 
225 aa  188  5e-47  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  46.26 
 
 
233 aa  188  5e-47  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_3055  two component transcriptional regulator, winged helix family  42.99 
 
 
227 aa  187  1e-46  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.703147  hitchhiker  0.000223036 
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  44.2 
 
 
224 aa  187  1e-46  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_008639  Cpha266_1205  two component transcriptional regulator  45.62 
 
 
222 aa  187  1e-46  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_013124  Afer_0200  two component transcriptional regulator, winged helix family  48.66 
 
 
242 aa  186  2e-46  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.0955644  n/a   
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  45.37 
 
 
236 aa  186  2e-46  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  43.24 
 
 
229 aa  186  2e-46  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_013132  Cpin_1247  two component transcriptional regulator, winged helix family  42.13 
 
 
235 aa  186  3e-46  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.464606  normal 
 
 
-
 
NC_002976  SERP0989  DNA-binding response regulator ArlR  45.58 
 
 
219 aa  185  4e-46  Staphylococcus epidermidis RP62A  Bacteria  normal  0.110636  n/a   
 
 
-
 
NC_013124  Afer_0558  two component transcriptional regulator, winged helix family  45.61 
 
 
237 aa  186  4e-46  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  44.34 
 
 
223 aa  185  5e-46  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_014248  Aazo_0389  winged helix family two component transcriptional regulator  48.87 
 
 
224 aa  185  6e-46  'Nostoc azollae' 0708  Bacteria  normal  0.667669  n/a   
 
 
-
 
NC_011060  Ppha_0994  two component transcriptional regulator, winged helix family  44.24 
 
 
227 aa  185  6e-46  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  0.337893  n/a   
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  45.45 
 
 
223 aa  184  8e-46  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_014212  Mesil_2637  two component transcriptional regulator, winged helix family  48.17 
 
 
227 aa  184  9e-46  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_3017  two component transcriptional regulator  52.04 
 
 
225 aa  184  9e-46  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  43.56 
 
 
230 aa  184  1.0000000000000001e-45  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1131  two component transcriptional regulator  45.98 
 
 
226 aa  183  2.0000000000000003e-45  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal 
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  42.67 
 
 
230 aa  183  2.0000000000000003e-45  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  41.78 
 
 
225 aa  182  3e-45  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_013037  Dfer_0453  two component transcriptional regulator, winged helix family  45.78 
 
 
225 aa  182  3e-45  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.904663  normal 
 
 
-
 
NC_008532  STER_0354  DNA-binding response regulator  47.06 
 
 
229 aa  182  3e-45  Streptococcus thermophilus LMD-9  Bacteria  unclonable  0.00000041064  n/a   
 
 
-
 
NC_005945  BAS2056  DNA-binding response regulator  46.26 
 
 
227 aa  182  4.0000000000000006e-45  Bacillus anthracis str. Sterne  Bacteria  normal  0.413172  n/a   
 
 
-
 
NC_011773  BCAH820_2240  DNA-binding response regulator  46.26 
 
 
227 aa  182  4.0000000000000006e-45  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  2.85177e-28 
 
 
-
 
NC_013061  Phep_3673  response regulator receiver  45.5 
 
 
227 aa  182  4.0000000000000006e-45  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_013525  Tter_1098  two component transcriptional regulator, winged helix family  45.41 
 
 
228 aa  182  4.0000000000000006e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_007530  GBAA_2212  DNA-binding response regulator  46.26 
 
 
227 aa  182  4.0000000000000006e-45  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  44.89 
 
 
223 aa  182  4.0000000000000006e-45  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_008261  CPF_1056  DNA-binding response regulator  46.36 
 
 
226 aa  182  4.0000000000000006e-45  Clostridium perfringens ATCC 13124  Bacteria  normal  0.775205  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  44.84 
 
 
226 aa  182  4.0000000000000006e-45  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_013946  Mrub_1103  two component transcriptional regulator, winged helix family  47.71 
 
 
227 aa  181  6e-45  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_008025  Dgeo_2318  two component transcriptional regulator  46.85 
 
 
225 aa  181  7e-45  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.642935  normal 
 
 
-
 
NC_013525  Tter_1435  two component transcriptional regulator, winged helix family  46.15 
 
 
233 aa  181  7e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009718  Fnod_0785  two component transcriptional regulator  42.66 
 
 
229 aa  181  8.000000000000001e-45  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.0635827  n/a   
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  46.19 
 
 
236 aa  181  1e-44  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  44.59 
 
 
229 aa  181  1e-44  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_010320  Teth514_0439  two component transcriptional regulator  43.5 
 
 
225 aa  180  1e-44  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000223011  n/a   
 
 
-
 
NC_008609  Ppro_3155  two component transcriptional regulator  45.29 
 
 
228 aa  181  1e-44  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_013165  Shel_13760  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  44.8 
 
 
225 aa  180  1e-44  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  44.25 
 
 
229 aa  180  2e-44  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  46.67 
 
 
225 aa  179  2e-44  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  41.78 
 
 
256 aa  179  2e-44  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  40.36 
 
 
228 aa  179  2e-44  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_013169  Ksed_03700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  45.29 
 
 
226 aa  179  2.9999999999999997e-44  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.132847 
 
 
-
 
NC_007519  Dde_2387  two component transcriptional regulator  44.49 
 
 
229 aa  179  2.9999999999999997e-44  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00115026  n/a   
 
 
-
 
NC_011725  BCB4264_A2194  DNA-binding response regulator  45.81 
 
 
227 aa  179  2.9999999999999997e-44  Bacillus cereus B4264  Bacteria  hitchhiker  0.00702475  n/a   
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  44.49 
 
 
229 aa  179  4e-44  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_009253  Dred_1903  two component transcriptional regulator  42.54 
 
 
230 aa  179  4e-44  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_1873  two component transcriptional regulator  44.5 
 
 
226 aa  178  7e-44  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_3069  two component transcriptional regulator  42.11 
 
 
230 aa  178  7e-44  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.0000000467461  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  43.44 
 
 
236 aa  177  8e-44  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_008261  CPF_2811  DNA-binding response regulator  40.54 
 
 
228 aa  177  8e-44  Clostridium perfringens ATCC 13124  Bacteria  normal  n/a   
 
 
-
 
NC_008578  Acel_1595  two component transcriptional regulator  46.64 
 
 
227 aa  177  8e-44  Acidothermus cellulolyticus 11B  Bacteria  normal  0.526383  normal  0.570373 
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  48.42 
 
 
225 aa  177  8e-44  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_09290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  44.64 
 
 
229 aa  177  1e-43  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  39.57 
 
 
239 aa  177  1e-43  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  46.64 
 
 
236 aa  177  1e-43  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  42.6 
 
 
230 aa  177  2e-43  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_007513  Syncc9902_1771  two component transcriptional regulator  42.74 
 
 
244 aa  176  2e-43  Synechococcus sp. CC9902  Bacteria  normal  n/a   
 
 
-
 
NC_008262  CPR_2497  DNA-binding response regulator  40.54 
 
 
228 aa  176  2e-43  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_32700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  43.5 
 
 
271 aa  177  2e-43  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.442824  normal  0.485424 
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  42.53 
 
 
222 aa  176  2e-43  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  40 
 
 
239 aa  176  3e-43  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  40 
 
 
239 aa  176  3e-43  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4549  two component transcriptional regulator, winged helix family  46.79 
 
 
221 aa  176  3e-43  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.703481  normal 
 
 
-
 
NC_011830  Dhaf_1005  two component transcriptional regulator, winged helix family  42.73 
 
 
227 aa  176  3e-43  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000255449  n/a   
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  44.2 
 
 
224 aa  176  3e-43  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_010814  Glov_0588  two component transcriptional regulator, winged helix family  45.29 
 
 
226 aa  176  3e-43  Geobacter lovleyi SZ  Bacteria  normal  0.944339  n/a   
 
 
-
 
NC_009767  Rcas_0997  two component transcriptional regulator  45.5 
 
 
230 aa  176  3e-43  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.679101  normal 
 
 
-
 
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