More than 300 homologs were found in PanDaTox collection
for query gene Mesil_1036 on replicon NC_014212
Organism: Meiothermus silvanus DSM 9946



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014212  Mesil_1036  two component transcriptional regulator, winged helix family  100 
 
 
227 aa  451  1.0000000000000001e-126  Meiothermus silvanus DSM 9946  Bacteria  normal  0.715621  normal  0.0491719 
 
 
-
 
NC_013946  Mrub_0644  two component transcriptional regulator, winged helix family  60.79 
 
 
218 aa  280  1e-74  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_013946  Mrub_0034  two component transcriptional regulator, winged helix family  49.78 
 
 
220 aa  209  3e-53  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_009939  Dgeo_3008  two component transcriptional regulator  49.34 
 
 
220 aa  190  1e-47  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_014212  Mesil_0819  two component transcriptional regulator, winged helix family  42.92 
 
 
217 aa  155  7e-37  Meiothermus silvanus DSM 9946  Bacteria  normal  0.138732  normal  0.638176 
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  41.56 
 
 
240 aa  154  1e-36  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_008025  Dgeo_2215  two component transcriptional regulator  42.92 
 
 
220 aa  152  4e-36  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_013946  Mrub_1034  two component transcriptional regulator, winged helix family  42.54 
 
 
219 aa  147  1.0000000000000001e-34  Meiothermus ruber DSM 1279  Bacteria  normal  0.171933  normal 
 
 
-
 
NC_010571  Oter_1407  two component transcriptional regulator  39.66 
 
 
265 aa  143  2e-33  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_3146  two component transcriptional regulator, winged helix family  43.61 
 
 
218 aa  142  4e-33  Meiothermus silvanus DSM 9946  Bacteria  normal  0.149495  normal 
 
 
-
 
NC_008010  Dgeo_2749  two component transcriptional regulator  41.92 
 
 
223 aa  141  8e-33  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.513844  n/a   
 
 
-
 
NC_004116  SAG2122  DNA-binding response regulator  38.03 
 
 
223 aa  139  3e-32  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS2999  DNA-binding response regulator  36.8 
 
 
224 aa  137  8.999999999999999e-32  Bacillus anthracis str. Sterne  Bacteria  normal  0.227145  n/a   
 
 
-
 
NC_007530  GBAA_3229  DNA-binding response regulator  36.8 
 
 
224 aa  137  8.999999999999999e-32  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_1841  two component transcriptional regulator  39.56 
 
 
216 aa  137  1e-31  Opitutus terrae PB90-1  Bacteria  normal  0.0207334  normal 
 
 
-
 
NC_007974  Rmet_4829  DNA-binding response regulator  38.16 
 
 
235 aa  137  1e-31  Cupriavidus metallidurans CH34  Bacteria  decreased coverage  0.00101292  normal  0.0130353 
 
 
-
 
NC_013161  Cyan8802_1445  two component transcriptional regulator, winged helix family  37.07 
 
 
225 aa  137  2e-31  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_1416  two component transcriptional regulator, winged helix family  37.07 
 
 
225 aa  137  2e-31  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013205  Aaci_2264  two component transcriptional regulator, winged helix family  39.57 
 
 
231 aa  137  2e-31  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  hitchhiker  0.00910741  n/a   
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  38.1 
 
 
225 aa  135  4e-31  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009504  BOV_A0210  DNA-binding response regulator  35.22 
 
 
225 aa  135  5e-31  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  36.28 
 
 
224 aa  135  7.000000000000001e-31  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_010681  Bphyt_3267  two component transcriptional regulator, winged helix family  37.33 
 
 
220 aa  134  8e-31  Burkholderia phytofirmans PsJN  Bacteria  normal  0.387524  normal 
 
 
-
 
NC_009436  Ent638_3617  DNA-binding transcriptional regulator BasR  37.44 
 
 
220 aa  134  9e-31  Enterobacter sp. 638  Bacteria  hitchhiker  0.0000270917  normal  0.430126 
 
 
-
 
NC_011729  PCC7424_5018  two component transcriptional regulator, winged helix family  37.5 
 
 
226 aa  134  9.999999999999999e-31  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_009802  CCC13826_1969  response regulator receiver domain-containing protein  36.73 
 
 
219 aa  134  9.999999999999999e-31  Campylobacter concisus 13826  Bacteria  normal  0.478098  n/a   
 
 
-
 
NC_014248  Aazo_2223  winged helix family two component transcriptional regulator  35.85 
 
 
229 aa  134  9.999999999999999e-31  'Nostoc azollae' 0708  Bacteria  normal  0.335669  n/a   
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  35.78 
 
 
222 aa  133  1.9999999999999998e-30  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  38.96 
 
 
226 aa  134  1.9999999999999998e-30  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  36.28 
 
 
224 aa  133  3e-30  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  36.28 
 
 
224 aa  133  3e-30  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_011138  MADE_02297  response regulator in two-component regulatory system with PhoQ  35.78 
 
 
224 aa  133  3e-30  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007951  Bxe_A0699  two component transcriptional regulator  36.89 
 
 
220 aa  133  3e-30  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_0224  two component transcriptional regulator  33.92 
 
 
221 aa  133  3e-30  Marinomonas sp. MWYL1  Bacteria  normal  0.0104787  normal 
 
 
-
 
NC_013946  Mrub_3033  two component transcriptional regulator, winged helix family  40.27 
 
 
218 aa  133  3e-30  Meiothermus ruber DSM 1279  Bacteria  normal  normal  0.190199 
 
 
-
 
NC_008825  Mpe_A0076  two component transcriptional regulator  39.13 
 
 
223 aa  132  3.9999999999999996e-30  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.225452 
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  36.28 
 
 
224 aa  132  3.9999999999999996e-30  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_3017  two component transcriptional regulator  39.34 
 
 
225 aa  132  3.9999999999999996e-30  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_007347  Reut_A1337  two component transcriptional regulator  38.6 
 
 
249 aa  132  5e-30  Ralstonia eutropha JMP134  Bacteria  normal  0.257065  n/a   
 
 
-
 
NC_013170  Ccur_03590  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  35.78 
 
 
226 aa  132  5e-30  Cryptobacterium curtum DSM 15641  Bacteria  normal  normal  0.0594239 
 
 
-
 
NC_014210  Ndas_4549  two component transcriptional regulator, winged helix family  38.1 
 
 
221 aa  132  5e-30  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.703481  normal 
 
 
-
 
NC_012880  Dd703_0392  DNA-binding transcriptional regulator BasR  35.5 
 
 
222 aa  132  5e-30  Dickeya dadantii Ech703  Bacteria  normal  0.421328  n/a   
 
 
-
 
NC_014212  Mesil_2637  two component transcriptional regulator, winged helix family  39.23 
 
 
227 aa  132  5e-30  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_009668  Oant_3252  two component transcriptional regulator  36.84 
 
 
220 aa  130  1.0000000000000001e-29  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_007577  PMT9312_1712  two component transcriptional regulator  39.26 
 
 
248 aa  131  1.0000000000000001e-29  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  39.52 
 
 
224 aa  130  1.0000000000000001e-29  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_009512  Pput_2735  two component transcriptional regulator  35.68 
 
 
219 aa  131  1.0000000000000001e-29  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_007494  RSP_3088  two component transcriptional regulator  35.24 
 
 
219 aa  130  2.0000000000000002e-29  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_1404  two component transcriptional regulator  38.46 
 
 
229 aa  130  2.0000000000000002e-29  Synechococcus elongatus PCC 7942  Bacteria  normal  0.153238  normal 
 
 
-
 
NC_007963  Csal_2596  two component transcriptional regulator  35.96 
 
 
233 aa  130  2.0000000000000002e-29  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.606495  n/a   
 
 
-
 
NC_009050  Rsph17029_3815  two component transcriptional regulator  35.24 
 
 
219 aa  130  2.0000000000000002e-29  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  0.681737  normal  0.25062 
 
 
-
 
NC_008740  Maqu_1287  two component transcriptional regulator  35.24 
 
 
221 aa  130  2.0000000000000002e-29  Marinobacter aquaeolei VT8  Bacteria  decreased coverage  0.00449543  n/a   
 
 
-
 
NC_008740  Maqu_3217  two component transcriptional regulator  35.24 
 
 
221 aa  130  2.0000000000000002e-29  Marinobacter aquaeolei VT8  Bacteria  normal  0.164246  n/a   
 
 
-
 
NC_013161  Cyan8802_4261  two component transcriptional regulator, winged helix family  34.91 
 
 
224 aa  130  2.0000000000000002e-29  Cyanothece sp. PCC 8802  Bacteria  normal  0.906422  normal  0.0109867 
 
 
-
 
NC_009091  P9301_18111  two-component response regulator  39.26 
 
 
248 aa  130  2.0000000000000002e-29  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_4687  two component transcriptional regulator  40.69 
 
 
223 aa  129  3e-29  Polaromonas sp. JS666  Bacteria  hitchhiker  0.000526997  normal 
 
 
-
 
NC_009523  RoseRS_1397  two component transcriptional regulator  38.53 
 
 
261 aa  129  3e-29  Roseiflexus sp. RS-1  Bacteria  normal  0.0231814  hitchhiker  0.000111966 
 
 
-
 
NC_008816  A9601_18291  two-component response regulator  39.26 
 
 
248 aa  129  3e-29  Prochlorococcus marinus str. AS9601  Bacteria  normal  0.276613  n/a   
 
 
-
 
NC_007298  Daro_0429  response regulator receiver:transcriptional regulatory protein, C-terminal  39.53 
 
 
223 aa  129  4.0000000000000003e-29  Dechloromonas aromatica RCB  Bacteria  normal  0.199286  decreased coverage  0.000258733 
 
 
-
 
NC_010682  Rpic_0470  two component transcriptional regulator, winged helix family  38.91 
 
 
236 aa  129  4.0000000000000003e-29  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_012856  Rpic12D_0454  two component transcriptional regulator, winged helix family  38.91 
 
 
235 aa  129  4.0000000000000003e-29  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_012912  Dd1591_0310  DNA-binding transcriptional regulator BasR  36.56 
 
 
232 aa  129  4.0000000000000003e-29  Dickeya zeae Ech1591  Bacteria  normal  0.0214332  n/a   
 
 
-
 
NC_008025  Dgeo_2318  two component transcriptional regulator  36.84 
 
 
225 aa  129  4.0000000000000003e-29  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.642935  normal 
 
 
-
 
NC_008781  Pnap_3105  two component transcriptional regulator  35.56 
 
 
219 aa  129  4.0000000000000003e-29  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.136173  normal 
 
 
-
 
NC_009972  Haur_0447  two component transcriptional regulator  38.3 
 
 
229 aa  129  4.0000000000000003e-29  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.000245325  n/a   
 
 
-
 
NC_013946  Mrub_1103  two component transcriptional regulator, winged helix family  37.8 
 
 
227 aa  129  4.0000000000000003e-29  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_4222  two component transcriptional regulator, winged helix family  34.91 
 
 
224 aa  129  4.0000000000000003e-29  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_009720  Xaut_3399  two component transcriptional regulator  35.37 
 
 
223 aa  129  5.0000000000000004e-29  Xanthobacter autotrophicus Py2  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_4628  two component transcriptional regulator, winged helix family  35.34 
 
 
224 aa  128  6e-29  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.000289587 
 
 
-
 
NC_011884  Cyan7425_2927  two component transcriptional regulator, winged helix family  36.64 
 
 
224 aa  128  7.000000000000001e-29  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_008781  Pnap_3958  two component transcriptional regulator  40.26 
 
 
224 aa  128  8.000000000000001e-29  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal  0.0314218 
 
 
-
 
NC_011662  Tmz1t_1940  two component transcriptional regulator, winged helix family  38.33 
 
 
219 aa  128  9.000000000000001e-29  Thauera sp. MZ1T  Bacteria  normal  0.359722  n/a   
 
 
-
 
NC_007413  Ava_3453  two component transcriptional regulator  32.71 
 
 
224 aa  128  9.000000000000001e-29  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_011989  Avi_1358  two component response regulator  36.4 
 
 
224 aa  128  9.000000000000001e-29  Agrobacterium vitis S4  Bacteria  normal  0.333715  n/a   
 
 
-
 
NC_010682  Rpic_0575  two component transcriptional regulator, winged helix family  36.12 
 
 
224 aa  127  1.0000000000000001e-28  Ralstonia pickettii 12J  Bacteria  normal  normal  0.21251 
 
 
-
 
NC_009505  BOV_0603  DNA-binding response regulator  37.72 
 
 
229 aa  127  1.0000000000000001e-28  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_010086  Bmul_5097  two component transcriptional regulator  38.43 
 
 
221 aa  127  1.0000000000000001e-28  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.361428  normal  0.112132 
 
 
-
 
NC_010622  Bphy_0469  two component transcriptional regulator  36.44 
 
 
220 aa  127  1.0000000000000001e-28  Burkholderia phymatum STM815  Bacteria  normal  0.601273  normal  0.0513669 
 
 
-
 
NC_007575  Suden_0317  two component transcriptional regulator  35.19 
 
 
224 aa  127  1.0000000000000001e-28  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  36.79 
 
 
223 aa  127  1.0000000000000001e-28  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_013522  Taci_0717  two component transcriptional regulator, winged helix family  32.9 
 
 
226 aa  127  1.0000000000000001e-28  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  hitchhiker  0.000154116  n/a   
 
 
-
 
NC_014151  Cfla_1294  two component transcriptional regulator, winged helix family  35.24 
 
 
218 aa  127  1.0000000000000001e-28  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0476117  hitchhiker  0.00354598 
 
 
-
 
NC_007948  Bpro_3674  two component transcriptional regulator  34.22 
 
 
219 aa  127  1.0000000000000001e-28  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  36.96 
 
 
225 aa  127  1.0000000000000001e-28  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  36.96 
 
 
225 aa  127  1.0000000000000001e-28  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  36.96 
 
 
225 aa  127  1.0000000000000001e-28  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_008254  Meso_0894  two component transcriptional regulator  38.6 
 
 
222 aa  127  1.0000000000000001e-28  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_012912  Dd1591_4177  two component transcriptional regulator, winged helix family  35.09 
 
 
223 aa  127  1.0000000000000001e-28  Dickeya zeae Ech1591  Bacteria  normal  0.622163  n/a   
 
 
-
 
NC_008709  Ping_1228  two component transcriptional regulator, winged helix family protein  34.51 
 
 
218 aa  127  1.0000000000000001e-28  Psychromonas ingrahamii 37  Bacteria  normal  normal  0.169339 
 
 
-
 
NC_009767  Rcas_2487  two component transcriptional regulator  39.66 
 
 
224 aa  126  2.0000000000000002e-28  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.431556  normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  38.97 
 
 
226 aa  127  2.0000000000000002e-28  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_010730  SYO3AOP1_0130  two component transcriptional regulator, winged helix family  34.88 
 
 
224 aa  127  2.0000000000000002e-28  Sulfurihydrogenibium sp. YO3AOP1  Bacteria  hitchhiker  0.00147609  n/a   
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  36.21 
 
 
225 aa  127  2.0000000000000002e-28  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  38.1 
 
 
226 aa  127  2.0000000000000002e-28  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010681  Bphyt_2190  two component transcriptional regulator, winged helix family  38.33 
 
 
219 aa  127  2.0000000000000002e-28  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_2625  two component transcriptional regulator  38.89 
 
 
231 aa  127  2.0000000000000002e-28  Roseiflexus sp. RS-1  Bacteria  normal  0.983258  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  37.66 
 
 
226 aa  127  2.0000000000000002e-28  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  38.53 
 
 
283 aa  127  2.0000000000000002e-28  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_011729  PCC7424_1341  two component transcriptional regulator, winged helix family  36.86 
 
 
226 aa  127  2.0000000000000002e-28  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_010505  Mrad2831_4988  two component transcriptional regulator  35.84 
 
 
225 aa  127  2.0000000000000002e-28  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  hitchhiker  0.000131605 
 
 
-
 
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