More than 300 homologs were found in PanDaTox collection
for query gene Mesil_1849 on replicon NC_014212
Organism: Meiothermus silvanus DSM 9946



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014212  Mesil_1849  response regulator receiver protein  100 
 
 
263 aa  519  1e-146  Meiothermus silvanus DSM 9946  Bacteria  normal  0.468098  normal  0.46427 
 
 
-
 
NC_013946  Mrub_0905  response regulator receiver protein  40.49 
 
 
295 aa  222  4.9999999999999996e-57  Meiothermus ruber DSM 1279  Bacteria  unclonable  0.00000000245258  normal 
 
 
-
 
NC_010571  Oter_0804  two component LuxR family transcriptional regulator  33.33 
 
 
204 aa  90.9  2e-17  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_0987  response regulator receiver protein  38.79 
 
 
414 aa  90.1  4e-17  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.332272 
 
 
-
 
NC_011146  Gbem_1708  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  41.88 
 
 
869 aa  87.4  2e-16  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_0842  response regulator receiver protein  35.11 
 
 
390 aa  87.8  2e-16  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.884409  normal 
 
 
-
 
NC_008554  Sfum_1934  two component, sigma54 specific, Fis family transcriptional regulator  38.98 
 
 
476 aa  87.8  2e-16  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.808753  normal  0.132653 
 
 
-
 
NC_011832  Mpal_1331  multi-sensor signal transduction histidine kinase  37.29 
 
 
576 aa  86.7  4e-16  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_012918  GM21_2194  response regulator receiver sensor signal transduction histidine kinase  37.07 
 
 
452 aa  86.3  5e-16  Geobacter sp. M21  Bacteria  n/a    normal  0.514859 
 
 
-
 
NC_010524  Lcho_0045  adenylate/guanylate cyclase  39.32 
 
 
382 aa  84.7  0.000000000000001  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_012918  GM21_2514  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  39.5 
 
 
869 aa  84.7  0.000000000000001  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011059  Paes_1429  response regulator receiver protein  39.67 
 
 
122 aa  84.7  0.000000000000001  Prosthecochloris aestuarii DSM 271  Bacteria  normal  normal  0.275463 
 
 
-
 
NC_007298  Daro_2788  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  37.38 
 
 
715 aa  84.3  0.000000000000002  Dechloromonas aromatica RCB  Bacteria  normal  0.941936  normal 
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  38.84 
 
 
231 aa  84.3  0.000000000000002  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013204  Elen_3054  two component transcriptional regulator, winged helix family  37.19 
 
 
237 aa  84.3  0.000000000000002  Eggerthella lenta DSM 2243  Bacteria  normal  normal 
 
 
-
 
NC_008312  Tery_3248  response regulator receiver protein  33.06 
 
 
121 aa  84.3  0.000000000000002  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.500247 
 
 
-
 
NC_009654  Mmwyl1_4400  two component transcriptional regulator  29.63 
 
 
236 aa  84  0.000000000000002  Marinomonas sp. MWYL1  Bacteria  normal  0.998417  normal 
 
 
-
 
NC_011146  Gbem_2025  response regulator receiver sensor signal transduction histidine kinase  37.5 
 
 
452 aa  82.8  0.000000000000005  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007796  Mhun_2749  response regulator receiver domain-containing protein  30.08 
 
 
436 aa  82.8  0.000000000000005  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_008009  Acid345_0504  response regulator receiver modulated metal dependent phosphohydrolase  37.61 
 
 
427 aa  82.8  0.000000000000006  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_007413  Ava_1086  multi-sensor hybrid histidine kinase  37.98 
 
 
1431 aa  82  0.000000000000008  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_3553  transcriptional regulator, Crp/Fnr family  31.25 
 
 
348 aa  82  0.00000000000001  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.528491 
 
 
-
 
NC_014248  Aazo_3138  response regulator receiver protein  35.54 
 
 
455 aa  81.6  0.00000000000001  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_1878  two component transcriptional regulator  37.82 
 
 
242 aa  81.6  0.00000000000001  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.559477 
 
 
-
 
NC_010571  Oter_0959  response regulator receiver sensor signal transduction histidine kinase  37.29 
 
 
372 aa  82  0.00000000000001  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_007614  Nmul_A2231  two component transcriptional regulator  33.6 
 
 
234 aa  81.6  0.00000000000001  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_3747  response regulator receiver protein  33.61 
 
 
121 aa  81.3  0.00000000000001  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_4611  response regulator receiver sensor signal transduction histidine kinase  36.13 
 
 
1002 aa  81.6  0.00000000000001  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.367657 
 
 
-
 
NC_004311  BRA0474  transcriptional regulatory protein OmpR, putative  36.13 
 
 
238 aa  80.9  0.00000000000002  Brucella suis 1330  Bacteria  normal  0.558106  n/a   
 
 
-
 
NC_011729  PCC7424_4207  two component transcriptional regulator, winged helix family  36.97 
 
 
247 aa  80.9  0.00000000000002  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_014248  Aazo_0581  winged helix family two component transcriptional regulator  37.82 
 
 
242 aa  81.3  0.00000000000002  'Nostoc azollae' 0708  Bacteria  normal  0.296955  n/a   
 
 
-
 
NC_011884  Cyan7425_4868  response regulator receiver protein  33.9 
 
 
143 aa  81.3  0.00000000000002  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_007484  Noc_2401  phosphate regulon transcriptional regulatory protein phoB  31.36 
 
 
229 aa  80.5  0.00000000000002  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0955  response regulator receiver domain-containing protein  30.77 
 
 
439 aa  80.9  0.00000000000002  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_2924  two component, sigma54 specific, Fis family transcriptional regulator  40.16 
 
 
470 aa  80.5  0.00000000000002  Geobacter metallireducens GS-15  Bacteria  normal  0.777319  hitchhiker  0.0000000000564278 
 
 
-
 
NC_011992  Dtpsy_2900  response regulator receiver protein  36.52 
 
 
121 aa  80.9  0.00000000000002  Acidovorax ebreus TPSY  Bacteria  normal  0.197839  n/a   
 
 
-
 
NC_008782  Ajs_3577  response regulator receiver protein  36.52 
 
 
121 aa  80.9  0.00000000000002  Acidovorax sp. JS42  Bacteria  normal  0.400966  normal  0.141746 
 
 
-
 
NC_009504  BOV_A0413  putative transcriptional regulatory protein OmpR  36.13 
 
 
238 aa  80.9  0.00000000000002  Brucella ovis ATCC 25840  Bacteria  normal  0.16231  n/a   
 
 
-
 
NC_007794  Saro_2281  two component transcriptional regulator  30 
 
 
229 aa  80.5  0.00000000000002  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.331932  n/a   
 
 
-
 
NC_011884  Cyan7425_1115  two component transcriptional regulator, winged helix family  37.82 
 
 
243 aa  81.3  0.00000000000002  Cyanothece sp. PCC 7425  Bacteria  normal  0.0950226  normal 
 
 
-
 
NC_012918  GM21_0684  two component, sigma54 specific, transcriptional regulator, Fis family  35.71 
 
 
469 aa  80.9  0.00000000000002  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.0000000000150794 
 
 
-
 
NC_008312  Tery_0954  two component transcriptional regulator  36.97 
 
 
243 aa  80.9  0.00000000000002  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.0817018 
 
 
-
 
NC_008312  Tery_3999  adenylate/guanylate cyclase  36.13 
 
 
351 aa  80.9  0.00000000000002  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.558191 
 
 
-
 
NC_008347  Mmar10_0766  two component transcriptional regulator  38.02 
 
 
233 aa  80.9  0.00000000000002  Maricaulis maris MCS10  Bacteria  normal  0.528482  normal  0.302775 
 
 
-
 
NC_012034  Athe_0580  response regulator receiver protein  39.17 
 
 
123 aa  80.5  0.00000000000003  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_3211  histidine kinase  30.32 
 
 
781 aa  80.1  0.00000000000003  Cyanothece sp. PCC 7425  Bacteria  normal  0.306218  normal  0.65795 
 
 
-
 
NC_011726  PCC8801_1234  response regulator receiver protein  35.54 
 
 
122 aa  80.1  0.00000000000003  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008786  Veis_3020  response regulator receiver protein  36.52 
 
 
121 aa  80.5  0.00000000000003  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.447611  normal 
 
 
-
 
NC_007498  Pcar_2316  response regulator  32.82 
 
 
527 aa  80.5  0.00000000000003  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.0000000000000645629  n/a   
 
 
-
 
NC_013161  Cyan8802_1264  response regulator receiver protein  35.54 
 
 
122 aa  80.1  0.00000000000003  Cyanothece sp. PCC 8802  Bacteria  normal  0.0578681  hitchhiker  0.00155192 
 
 
-
 
NC_013739  Cwoe_3139  response regulator receiver modulated diguanylate cyclase  32.5 
 
 
676 aa  80.5  0.00000000000003  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.990746 
 
 
-
 
NC_011901  Tgr7_2904  response regulator receiver protein  37.17 
 
 
137 aa  80.5  0.00000000000003  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_3382  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  30.67 
 
 
594 aa  79.7  0.00000000000004  Marinomonas sp. MWYL1  Bacteria  normal  normal  0.371129 
 
 
-
 
NC_010506  Swoo_1514  response regulator receiver protein  37.1 
 
 
382 aa  80.1  0.00000000000004  Shewanella woodyi ATCC 51908  Bacteria  normal  0.222117  hitchhiker  0.00633337 
 
 
-
 
NC_003910  CPS_4597  osmolarity response regulator  33.33 
 
 
240 aa  79.7  0.00000000000004  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_007412  Ava_C0163  multi-component transcriptional regulator  34.51 
 
 
725 aa  80.1  0.00000000000004  Anabaena variabilis ATCC 29413  Bacteria  normal  0.892768  normal 
 
 
-
 
NC_009483  Gura_4171  CheA signal transduction histidine kinase  40.68 
 
 
686 aa  79.7  0.00000000000004  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_0856  response regulator receiver domain-containing protein  38.26 
 
 
120 aa  79.7  0.00000000000004  Synechococcus elongatus PCC 7942  Bacteria  normal  0.0758877  normal  0.0586548 
 
 
-
 
NC_011145  AnaeK_2309  response regulator receiver modulated diguanylate cyclase  36.44 
 
 
434 aa  79.7  0.00000000000004  Anaeromyxobacter sp. K  Bacteria  normal  0.484645  n/a   
 
 
-
 
NC_009712  Mboo_1464  multi-sensor signal transduction histidine kinase  35.25 
 
 
579 aa  79.7  0.00000000000004  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.164507  normal 
 
 
-
 
NC_010571  Oter_0776  multi-sensor hybrid histidine kinase  36.13 
 
 
1559 aa  80.1  0.00000000000004  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_011891  A2cp1_2397  response regulator receiver modulated diguanylate cyclase  36.44 
 
 
434 aa  79.7  0.00000000000004  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.593336  n/a   
 
 
-
 
NC_013216  Dtox_1955  two component transcriptional regulator, winged helix family  35.54 
 
 
236 aa  79.7  0.00000000000005  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.295041  normal 
 
 
-
 
NC_007404  Tbd_0085  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  38.52 
 
 
738 aa  79.3  0.00000000000005  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal  0.127866 
 
 
-
 
NC_013730  Slin_1271  transcriptional regulator, Crp/Fnr family  29.69 
 
 
350 aa  79.3  0.00000000000005  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_1086  response regulator receiver modulated metal dependent phosphohydrolase  32.77 
 
 
331 aa  79.7  0.00000000000005  Marinomonas sp. MWYL1  Bacteria  normal  0.226857  hitchhiker  0.0000000112469 
 
 
-
 
NC_010524  Lcho_3464  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  34.06 
 
 
704 aa  79.7  0.00000000000005  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.140727 
 
 
-
 
NC_009972  Haur_0605  adenylate/guanylate cyclase  35 
 
 
355 aa  79.3  0.00000000000005  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.657653  n/a   
 
 
-
 
NC_008752  Aave_0902  response regulator receiver protein  35.65 
 
 
121 aa  79.3  0.00000000000006  Acidovorax citrulli AAC00-1  Bacteria  normal  normal  0.844306 
 
 
-
 
NC_013161  Cyan8802_4345  response regulator receiver protein  36.21 
 
 
122 aa  79.3  0.00000000000006  Cyanothece sp. PCC 8802  Bacteria  normal  0.114649  normal 
 
 
-
 
NC_011726  PCC8801_4285  response regulator receiver protein  36.21 
 
 
122 aa  79.3  0.00000000000006  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_007413  Ava_2562  response regulator receiver Signal transduction histidine kinase  32.85 
 
 
437 aa  79  0.00000000000008  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_010524  Lcho_3970  response regulator receiver protein  35.65 
 
 
121 aa  79  0.00000000000008  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0244969 
 
 
-
 
NC_008609  Ppro_0710  two component, sigma54 specific, Fis family transcriptional regulator  37.29 
 
 
456 aa  78.6  0.00000000000009  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009092  Shew_2749  two component transcriptional regulator  28.79 
 
 
241 aa  78.6  0.00000000000009  Shewanella loihica PV-4  Bacteria  decreased coverage  0.00000593879  unclonable  0.00000330773 
 
 
-
 
NC_002939  GSU0598  sigma-54 dependent DNA-binding response regulator  39.34 
 
 
470 aa  78.2  0.0000000000001  Geobacter sulfurreducens PCA  Bacteria  normal  0.885444  n/a   
 
 
-
 
NC_011729  PCC7424_1976  multi-sensor signal transduction histidine kinase  35.04 
 
 
1383 aa  78.2  0.0000000000001  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.624185 
 
 
-
 
NC_011146  Gbem_0671  two component, sigma54 specific, transcriptional regulator, Fis family  36.97 
 
 
469 aa  78.6  0.0000000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_5320  winged helix family two component transcriptional regulator  27.19 
 
 
242 aa  78.2  0.0000000000001  Pseudomonas putida KT2440  Bacteria  normal  normal  0.023746 
 
 
-
 
NC_004578  PSPTO_5477  phosphate regulon transcriptional regulatory protein PhoB  27.31 
 
 
229 aa  77.8  0.0000000000001  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_013161  Cyan8802_2353  two component transcriptional regulator, winged helix family  36.13 
 
 
243 aa  78.2  0.0000000000001  Cyanothece sp. PCC 8802  Bacteria  normal  0.0794558  normal 
 
 
-
 
NC_011830  Dhaf_1237  two component transcriptional regulator, winged helix family  31.37 
 
 
234 aa  78.2  0.0000000000001  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.178035  n/a   
 
 
-
 
NC_010322  PputGB1_5367  two component transcriptional regulator  27.19 
 
 
229 aa  78.6  0.0000000000001  Pseudomonas putida GB-1  Bacteria  normal  normal  0.400776 
 
 
-
 
NC_010501  PputW619_0154  two component transcriptional regulator  27.19 
 
 
229 aa  78.2  0.0000000000001  Pseudomonas putida W619  Bacteria  normal  normal  0.596099 
 
 
-
 
NC_012560  Avin_25160  response regulator  33.33 
 
 
356 aa  78.6  0.0000000000001  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_0059  response regulator receiver domain-containing protein  34.19 
 
 
125 aa  78.6  0.0000000000001  Anabaena variabilis ATCC 29413  Bacteria  normal  0.157498  normal  0.212271 
 
 
-
 
NC_010002  Daci_1576  CheA signal transduction histidine kinase  34.82 
 
 
2137 aa  78.2  0.0000000000001  Delftia acidovorans SPH-1  Bacteria  normal  0.167147  normal  0.557453 
 
 
-
 
NC_010001  Cphy_0015  two component transcriptional regulator  29.02 
 
 
228 aa  78.6  0.0000000000001  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_1453  two component transcriptional regulator  37.82 
 
 
244 aa  78.2  0.0000000000001  Synechococcus elongatus PCC 7942  Bacteria  normal  0.952418  normal  0.0249242 
 
 
-
 
NC_007614  Nmul_A0335  response regulator receiver/GGDEF/EAL domain-containing protein  33.33 
 
 
980 aa  77.8  0.0000000000001  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.376364  n/a   
 
 
-
 
NC_007760  Adeh_1095  response regulator receiver domain-containing protein  35.71 
 
 
138 aa  78.2  0.0000000000001  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.117755  n/a   
 
 
-
 
NC_009512  Pput_5228  two component transcriptional regulator  27.19 
 
 
229 aa  78.6  0.0000000000001  Pseudomonas putida F1  Bacteria  normal  0.661336  normal  0.450139 
 
 
-
 
NC_007912  Sde_2977  response regulator receiver domain-containing protein  34.48 
 
 
303 aa  77.8  0.0000000000001  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.13601 
 
 
-
 
NC_008709  Ping_3328  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  36.52 
 
 
711 aa  78.2  0.0000000000001  Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_0612  response regulator receiver protein  37.5 
 
 
152 aa  77.8  0.0000000000001  Ralstonia pickettii 12J  Bacteria  normal  0.296044  normal 
 
 
-
 
NC_011726  PCC8801_2302  two component transcriptional regulator, winged helix family  36.13 
 
 
243 aa  78.2  0.0000000000001  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_012856  Rpic12D_0560  response regulator receiver protein  37.5 
 
 
165 aa  78.2  0.0000000000001  Ralstonia pickettii 12D  Bacteria  normal  0.595412  normal 
 
 
-
 
NC_009831  Ssed_3303  two component transcriptional regulator  26.85 
 
 
229 aa  78.2  0.0000000000001  Shewanella sediminis HAW-EB3  Bacteria  unclonable  0.0000000702519  hitchhiker  0.00000106408 
 
 
-
 
NC_010501  PputW619_0472  response regulator receiver protein  33.59 
 
 
133 aa  78.2  0.0000000000001  Pseudomonas putida W619  Bacteria  normal  0.418097  normal 
 
 
-
 
NC_002977  MCA3105  DNA-binding response regulator PhoB  27.93 
 
 
232 aa  77.8  0.0000000000002  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
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