144 homologs were found in PanDaTox collection
for query gene Hlac_1013 on replicon NC_012029
Organism: Halorubrum lacusprofundi ATCC 49239



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_012029  Hlac_1013  methylmalonyl-CoA epimerase  100 
 
 
128 aa  247  3e-65  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  0.752457  normal 
 
 
-
 
NC_013202  Hmuk_2887  methylmalonyl-CoA epimerase  75.38 
 
 
129 aa  167  5e-41  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.228803  normal 
 
 
-
 
NC_013743  Htur_1989  methylmalonyl-CoA epimerase  63.28 
 
 
127 aa  159  2e-38  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013922  Nmag_0555  methylmalonyl-CoA epimerase  58.59 
 
 
127 aa  154  3e-37  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_009718  Fnod_1316  glyoxalase/bleomycin resistance protein/dioxygenase  40.31 
 
 
135 aa  96.7  9e-20  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
NC_013946  Mrub_2348  methylmalonyl-CoA epimerase  43.75 
 
 
131 aa  95.5  2e-19  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_5865  methylmalonyl-CoA epimerase  43.75 
 
 
136 aa  94.7  3e-19  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_009616  Tmel_0586  glyoxalase/bleomycin resistance protein/dioxygenase  36.43 
 
 
135 aa  94  6e-19  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_1488  methylmalonyl-CoA epimerase  36.92 
 
 
134 aa  94  7e-19  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.383789  normal  0.131397 
 
 
-
 
NC_009943  Dole_0080  glyoxalase/bleomycin resistance protein/dioxygenase  36.92 
 
 
135 aa  90.5  6e-18  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0425619  n/a   
 
 
-
 
NC_008554  Sfum_0455  glyoxalase/bleomycin resistance protein/dioxygenase  40.46 
 
 
134 aa  90.1  8e-18  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.571993 
 
 
-
 
NC_010003  Pmob_0552  methylmalonyl-CoA epimerase  36.15 
 
 
134 aa  89.4  1e-17  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_5823  methylmalonyl-CoA epimerase  37.01 
 
 
135 aa  89  2e-17  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.609352 
 
 
-
 
NC_007333  Tfu_2395  methylmalonyl-CoA epimerase  37.31 
 
 
147 aa  88.2  3e-17  Thermobifida fusca YX  Bacteria  normal  0.754558  n/a   
 
 
-
 
NC_013525  Tter_1623  methylmalonyl-CoA epimerase  39.53 
 
 
136 aa  88.6  3e-17  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009441  Fjoh_0659  glyoxalase/bleomycin resistance protein/dioxygenase  34.38 
 
 
134 aa  88.6  3e-17  Flavobacterium johnsoniae UW101  Bacteria  hitchhiker  0.00502246  n/a   
 
 
-
 
NC_013124  Afer_0104  methylmalonyl-CoA epimerase  46.09 
 
 
137 aa  88.6  3e-17  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_3306  methylmalonyl-CoA epimerase  40.16 
 
 
135 aa  88.6  3e-17  Opitutus terrae PB90-1  Bacteria  normal  0.369567  normal 
 
 
-
 
NC_010655  Amuc_0200  methylmalonyl-CoA epimerase  36.15 
 
 
140 aa  88.6  3e-17  Akkermansia muciniphila ATCC BAA-835  Bacteria  hitchhiker  0.000715247  normal  0.843381 
 
 
-
 
NC_013595  Sros_1696  methylmalonyl-CoA epimerase  36.57 
 
 
140 aa  85.5  2e-16  Streptosporangium roseum DSM 43021  Bacteria  normal  0.019096  normal  0.134039 
 
 
-
 
NC_012793  GWCH70_2285  methylmalonyl-CoA epimerase  37.21 
 
 
140 aa  85.9  2e-16  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000102737  n/a   
 
 
-
 
NC_013061  Phep_1564  methylmalonyl-CoA epimerase  34.88 
 
 
134 aa  85.9  2e-16  Pedobacter heparinus DSM 2366  Bacteria  normal  normal  0.395959 
 
 
-
 
NC_009953  Sare_3993  glyoxalase/bleomycin resistance protein/dioxygenase  37.88 
 
 
159 aa  85.5  2e-16  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00061687 
 
 
-
 
NC_010320  Teth514_1852  glyoxalase/bleomycin resistance protein/dioxygenase  33.59 
 
 
133 aa  85.9  2e-16  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
CP001800  Ssol_0230  methylmalonyl-CoA epimerase  35.07 
 
 
142 aa  84.7  4e-16  Sulfolobus solfataricus 98/2  Archaea  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0306  methylmalonyl-CoA epimerase  36.43 
 
 
141 aa  84  6e-16  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_010085  Nmar_0953  glyoxalase/bleomycin resistance protein/dioxygenase  33.59 
 
 
131 aa  84  7e-16  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  0.0254493 
 
 
-
 
NC_014212  Mesil_0680  methylmalonyl-CoA epimerase  41.67 
 
 
131 aa  83.6  8e-16  Meiothermus silvanus DSM 9946  Bacteria  normal  0.227621  normal  0.151437 
 
 
-
 
NC_009523  RoseRS_0480  glyoxalase/bleomycin resistance protein/dioxygenase  38.3 
 
 
134 aa  83.6  8e-16  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_0152  glyoxalase/bleomycin resistance protein/dioxygenase  38.3 
 
 
134 aa  83.6  9e-16  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_1258  methylmalonyl-CoA epimerase  37.31 
 
 
147 aa  83.6  9e-16  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_0655  glyoxalase/bleomycin resistance protein/dioxygenase  35.66 
 
 
134 aa  82.8  0.000000000000001  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000000195436  n/a   
 
 
-
 
NC_014230  CA2559_03285  Lactoylglutathione lyase and related lyase  34.88 
 
 
135 aa  82.8  0.000000000000002  Croceibacter atlanticus HTCC2559  Bacteria  normal  0.275732  n/a   
 
 
-
 
NC_014210  Ndas_0356  methylmalonyl-CoA epimerase  38.36 
 
 
192 aa  82.8  0.000000000000002  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0916  methylmalonyl-CoA epimerase  35.07 
 
 
140 aa  82  0.000000000000003  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.311023 
 
 
-
 
NC_013037  Dfer_3197  methylmalonyl-CoA epimerase  36.22 
 
 
134 aa  81.6  0.000000000000003  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_0571  methylmalonyl-CoA epimerase  38.76 
 
 
137 aa  81.3  0.000000000000004  Geobacter sp. M21  Bacteria  n/a    hitchhiker  3.82853e-18 
 
 
-
 
NC_010814  Glov_3258  methylmalonyl-CoA epimerase  37.21 
 
 
134 aa  81.3  0.000000000000004  Geobacter lovleyi SZ  Bacteria  hitchhiker  0.0000316472  n/a   
 
 
-
 
NC_009440  Msed_0639  methylmalonyl-CoA epimerase  34.85 
 
 
140 aa  80.9  0.000000000000005  Metallosphaera sedula DSM 5348  Archaea  normal  0.237468  normal  0.259775 
 
 
-
 
NC_008009  Acid345_2364  methylmalonyl-CoA epimerase  38.28 
 
 
135 aa  80.9  0.000000000000006  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_0522  glyoxalase/bleomycin resistance protein/dioxygenase  34.38 
 
 
134 aa  80.9  0.000000000000006  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.0000000014865  n/a   
 
 
-
 
NC_009380  Strop_3611  glyoxalase/bleomycin resistance protein/dioxygenase  37.12 
 
 
157 aa  80.5  0.000000000000008  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_008025  Dgeo_1790  glyoxalase/bleomycin resistance protein/dioxygenase  41.09 
 
 
158 aa  80.1  0.00000000000001  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0558  methylmalonyl-CoA epimerase  36.43 
 
 
137 aa  80.1  0.00000000000001  Geobacter bemidjiensis Bem  Bacteria  unclonable  0.000000000977172  n/a   
 
 
-
 
NC_002939  GSU3303  methylmalonyl-CoA epimerase  39.23 
 
 
134 aa  79.3  0.00000000000002  Geobacter sulfurreducens PCA  Bacteria  hitchhiker  0.000981467  n/a   
 
 
-
 
NC_002950  PG1613  glyoxalase family protein  35.16 
 
 
134 aa  79.3  0.00000000000002  Porphyromonas gingivalis W83  Bacteria  n/a    normal 
 
 
-
 
NC_007517  Gmet_3253  methylmalonyl-CoA epimerase  34.88 
 
 
134 aa  79.3  0.00000000000002  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000018375  hitchhiker  3.27573e-17 
 
 
-
 
NC_013132  Cpin_0228  methylmalonyl-CoA epimerase  34.11 
 
 
132 aa  78.2  0.00000000000004  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_1796  methylmalonyl-CoA epimerase  36.43 
 
 
170 aa  77.8  0.00000000000005  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_2781  methylmalonyl-CoA epimerase  35.34 
 
 
141 aa  77.4  0.00000000000007  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_1282  glyoxalase/bleomycin resistance protein/dioxygenase  33.59 
 
 
134 aa  76.3  0.0000000000001  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_2507  glyoxalase/bleomycin resistance protein/dioxygenase  39.85 
 
 
141 aa  76.3  0.0000000000001  Frankia sp. EAN1pec  Bacteria  normal  0.0106102  normal 
 
 
-
 
NC_011894  Mnod_4142  methylmalonyl-CoA epimerase  41.98 
 
 
134 aa  75.5  0.0000000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.65243  n/a   
 
 
-
 
NC_011060  Ppha_1170  methylmalonyl-CoA epimerase  32.82 
 
 
135 aa  75.9  0.0000000000002  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  0.107967  n/a   
 
 
-
 
NC_013522  Taci_0290  methylmalonyl-CoA epimerase  33.59 
 
 
133 aa  75.9  0.0000000000002  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_6000  methylmalonyl-CoA epimerase  37.98 
 
 
143 aa  75.5  0.0000000000003  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.0251153 
 
 
-
 
NC_010511  M446_4406  methylmalonyl-CoA epimerase  41.98 
 
 
134 aa  75.1  0.0000000000003  Methylobacterium sp. 4-46  Bacteria  normal  0.865386  normal  0.62826 
 
 
-
 
NC_013510  Tcur_3891  methylmalonyl-CoA epimerase  33.33 
 
 
145 aa  74.7  0.0000000000004  Thermomonospora curvata DSM 43183  Bacteria  normal  0.394666  n/a   
 
 
-
 
NC_009972  Haur_2006  glyoxalase/bleomycin resistance protein/dioxygenase  39.23 
 
 
140 aa  73.6  0.000000000001  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_0981  methylmalonyl-CoA epimerase  48.15 
 
 
139 aa  72  0.000000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.0245792  normal  0.390705 
 
 
-
 
NC_013926  Aboo_1361  methylmalonyl-CoA epimerase  33.59 
 
 
129 aa  72.4  0.000000000002  Aciduliprofundum boonei T469  Archaea  unclonable  2.7651e-17  n/a   
 
 
-
 
NC_013169  Ksed_09410  methylmalonyl-CoA epimerase  37.5 
 
 
145 aa  71.6  0.000000000003  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.990135  normal  0.273906 
 
 
-
 
NC_010581  Bind_2198  methylmalonyl-CoA epimerase  40.6 
 
 
136 aa  71.2  0.000000000005  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_013235  Namu_3104  methylmalonyl-CoA epimerase  38.28 
 
 
163 aa  70.9  0.000000000006  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.000698993  hitchhiker  0.0000492352 
 
 
-
 
NC_009565  TBFG_11354  hypothetical protein  34.11 
 
 
151 aa  70.5  0.000000000007  Mycobacterium tuberculosis F11  Bacteria  normal  0.498935  normal 
 
 
-
 
NC_009667  Oant_2407  methylmalonyl-CoA epimerase  37.4 
 
 
134 aa  70.5  0.000000000007  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.914364  n/a   
 
 
-
 
NC_007493  RSP_0812  methylmalonyl-CoA epimerase  37.21 
 
 
134 aa  69.3  0.00000000002  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  n/a   
 
 
-
 
NC_008146  Mmcs_3865  methylmalonyl-CoA epimerase  31.82 
 
 
156 aa  68.9  0.00000000002  Mycobacterium sp. MCS  Bacteria  normal  0.241683  n/a   
 
 
-
 
NC_013093  Amir_6105  methylmalonyl-CoA epimerase  35.88 
 
 
146 aa  68.9  0.00000000002  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_3939  methylmalonyl-CoA epimerase  31.82 
 
 
156 aa  68.9  0.00000000002  Mycobacterium sp. KMS  Bacteria  normal  0.368557  normal  0.0232297 
 
 
-
 
NC_009049  Rsph17029_2469  glyoxalase/bleomycin resistance protein/dioxygenase  37.21 
 
 
134 aa  68.9  0.00000000002  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.186921 
 
 
-
 
NC_009505  BOV_0813  methylmalonyl-CoA epimerase  36.64 
 
 
134 aa  68.9  0.00000000002  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_007512  Plut_1289  lactoylglutathione lyase  32.31 
 
 
137 aa  68.6  0.00000000003  Chlorobium luteolum DSM 273  Bacteria  normal  normal 
 
 
-
 
NC_011891  A2cp1_4223  methylmalonyl-CoA epimerase  35.43 
 
 
133 aa  68.6  0.00000000003  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_1038  methylmalonyl-CoA epimerase  38.52 
 
 
134 aa  68.6  0.00000000003  Chelativorans sp. BNC1  Bacteria  hitchhiker  0.00716429  n/a   
 
 
-
 
NC_009675  Anae109_0349  glyoxalase/bleomycin resistance protein/dioxygenase  43.21 
 
 
134 aa  68.6  0.00000000003  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.0717499  normal  0.143694 
 
 
-
 
NC_013159  Svir_28560  methylmalonyl-CoA epimerase  35.21 
 
 
153 aa  68.6  0.00000000003  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal  0.215327 
 
 
-
 
NC_008048  Sala_1220  glyoxalase/bleomycin resistance protein/dioxygenase  36.96 
 
 
146 aa  68.2  0.00000000004  Sphingopyxis alaskensis RB2256  Bacteria  normal  0.019887  normal 
 
 
-
 
NC_009077  Mjls_3851  methylmalonyl-CoA epimerase  31.06 
 
 
156 aa  67.8  0.00000000004  Mycobacterium sp. JLS  Bacteria  normal  hitchhiker  0.00602371 
 
 
-
 
NC_011666  Msil_2934  methylmalonyl-CoA epimerase  37.98 
 
 
134 aa  68.2  0.00000000004  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_011725  BCB4264_A1916  glyoxalase family protein  30.3 
 
 
139 aa  67.8  0.00000000004  Bacillus cereus B4264  Bacteria  normal  0.037102  n/a   
 
 
-
 
NC_007760  Adeh_4074  methylmalonyl-CoA epimerase  34.65 
 
 
133 aa  67.8  0.00000000005  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.0584893  n/a   
 
 
-
 
NC_008044  TM1040_0637  methylmalonyl-CoA epimerase  38.35 
 
 
134 aa  67.8  0.00000000005  Ruegeria sp. TM1040  Bacteria  normal  normal  0.355591 
 
 
-
 
NC_008726  Mvan_4306  glyoxalase/bleomycin resistance protein/dioxygenase  33.33 
 
 
161 aa  67.8  0.00000000005  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal  0.725625 
 
 
-
 
NC_010505  Mrad2831_2043  methylmalonyl-CoA epimerase  38.17 
 
 
134 aa  67.8  0.00000000005  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.370344  normal 
 
 
-
 
NC_011145  AnaeK_4198  methylmalonyl-CoA epimerase  35.43 
 
 
134 aa  67.8  0.00000000005  Anaeromyxobacter sp. K  Bacteria  normal  0.152541  n/a   
 
 
-
 
NC_004310  BR0818  glyoxalase family protein  36.64 
 
 
134 aa  67.4  0.00000000006  Brucella suis 1330  Bacteria  normal  0.688033  n/a   
 
 
-
 
NC_009338  Mflv_2339  glyoxalase/bleomycin resistance protein/dioxygenase  33.33 
 
 
168 aa  67.4  0.00000000006  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.630848  normal  0.527959 
 
 
-
 
NC_008148  Rxyl_1869  methylmalonyl-CoA epimerase  36.43 
 
 
134 aa  67  0.00000000008  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.441583  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1774  glyoxalase/bleomycin resistance protein/dioxygenase  28.79 
 
 
139 aa  67  0.00000000009  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.0000533955  n/a   
 
 
-
 
NC_008639  Cpha266_1167  methylmalonyl-CoA epimerase  29.77 
 
 
135 aa  66.2  0.0000000001  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  0.217696  n/a   
 
 
-
 
NC_008686  Pden_2178  glyoxalase/bleomycin resistance protein/dioxygenase  35.66 
 
 
134 aa  65.9  0.0000000002  Paracoccus denitrificans PD1222  Bacteria  normal  0.794327  normal 
 
 
-
 
NC_005957  BT9727_1752  glyoxalase family protein  30.08 
 
 
139 aa  65.5  0.0000000003  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.000000441097  n/a   
 
 
-
 
NC_006274  BCZK1730  glyoxalase family protein  30.08 
 
 
139 aa  65.5  0.0000000003  Bacillus cereus E33L  Bacteria  hitchhiker  0.00522629  n/a   
 
 
-
 
NC_013757  Gobs_4113  methylmalonyl-CoA epimerase  34.11 
 
 
162 aa  65.1  0.0000000003  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.0776501  n/a   
 
 
-
 
NC_010803  Clim_0871  methylmalonyl-CoA epimerase  30.53 
 
 
135 aa  65.1  0.0000000003  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1946  glyoxalase family protein  30.08 
 
 
139 aa  65.5  0.0000000003  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  2.5587800000000002e-23 
 
 
-
 
NC_010172  Mext_1069  methylmalonyl-CoA epimerase  35.88 
 
 
134 aa  65.1  0.0000000004  Methylobacterium extorquens PA1  Bacteria  normal  0.17549  normal  0.247158 
 
 
-
 
NC_014158  Tpau_1264  methylmalonyl-CoA epimerase  30.43 
 
 
167 aa  64.7  0.0000000004  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.0685112  n/a   
 
 
-
 
NC_011757  Mchl_1198  methylmalonyl-CoA epimerase  35.88 
 
 
134 aa  65.1  0.0000000004  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
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