More than 300 homologs were found in PanDaTox collection
for query gene Avi_5253 on replicon NC_011988
Organism: Agrobacterium vitis S4



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011988  Avi_5253  ABC transporter membrane spanning protein (sugars)  100 
 
 
354 aa  701    Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_012880  Dd703_1347  binding-protein-dependent transport systems inner membrane component  58.5 
 
 
347 aa  400  9.999999999999999e-111  Dickeya dadantii Ech703  Bacteria  normal  0.113073  n/a   
 
 
-
 
NC_012912  Dd1591_4124  binding-protein-dependent transport systems inner membrane component  58.57 
 
 
348 aa  397  1e-109  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_0501  binding-protein-dependent transport systems inner membrane component  36.21 
 
 
282 aa  194  2e-48  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.00270449  n/a   
 
 
-
 
NC_012852  Rleg_6132  binding-protein-dependent transport systems inner membrane component  40.34 
 
 
280 aa  191  2e-47  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.146184  normal  0.293497 
 
 
-
 
NC_011371  Rleg2_6544  binding-protein-dependent transport systems inner membrane component  39.5 
 
 
280 aa  187  2e-46  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.427721 
 
 
-
 
NC_008698  Tpen_1176  binding-protein-dependent transport systems inner membrane component  37.97 
 
 
278 aa  182  8.000000000000001e-45  Thermofilum pendens Hrk 5  Archaea  normal  0.698198  n/a   
 
 
-
 
NC_008148  Rxyl_2069  binding-protein-dependent transport systems inner membrane component  36.76 
 
 
310 aa  160  3e-38  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_007802  Jann_3555  binding-protein-dependent transport systems inner membrane component  36.97 
 
 
279 aa  139  4.999999999999999e-32  Jannaschia sp. CCS1  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_1682  binding-protein-dependent transport systems inner membrane component  34.95 
 
 
275 aa  139  1e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.299262  normal 
 
 
-
 
NC_009636  Smed_2422  binding-protein-dependent transport systems inner membrane component  38.16 
 
 
277 aa  135  9e-31  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.161716 
 
 
-
 
NC_009667  Oant_0352  binding-protein-dependent transport systems inner membrane component  37.2 
 
 
277 aa  133  3.9999999999999996e-30  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_011366  Rleg2_5850  binding-protein-dependent transport systems inner membrane component  36.71 
 
 
276 aa  129  5.0000000000000004e-29  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.590535  normal 
 
 
-
 
NC_012858  Rleg_6763  binding-protein-dependent transport systems inner membrane component  36.71 
 
 
276 aa  128  1.0000000000000001e-28  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.18605  normal 
 
 
-
 
NC_013922  Nmag_1153  binding-protein-dependent transport systems inner membrane component  37.45 
 
 
326 aa  128  2.0000000000000002e-28  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_013595  Sros_2192  putative sugar ABC transporter, permease protein  35.51 
 
 
283 aa  127  4.0000000000000003e-28  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013172  Bfae_15400  carbohydrate ABC transporter membrane protein  31.49 
 
 
288 aa  126  5e-28  Brachybacterium faecium DSM 4810  Bacteria  normal  0.287612  n/a   
 
 
-
 
NC_012853  Rleg_5696  binding-protein-dependent transport systems inner membrane component  32.08 
 
 
283 aa  125  1e-27  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.697019  normal  0.0828938 
 
 
-
 
NC_008346  Swol_0403  putative integral membrane transport protein  32.27 
 
 
279 aa  124  2e-27  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_012848  Rleg_4865  binding-protein-dependent transport systems inner membrane component  37.1 
 
 
296 aa  124  3e-27  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.174421 
 
 
-
 
NC_008786  Veis_2280  binding-protein-dependent transport systems inner membrane component  33.82 
 
 
280 aa  124  3e-27  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.326107  normal 
 
 
-
 
NC_009664  Krad_3732  binding-protein-dependent transport systems inner membrane component  36.45 
 
 
307 aa  124  3e-27  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.151676  hitchhiker  0.00569855 
 
 
-
 
NC_008043  TM1040_3397  binding-protein-dependent transport systems inner membrane component  30.58 
 
 
287 aa  123  6e-27  Ruegeria sp. TM1040  Bacteria  normal  0.141396  normal  0.659935 
 
 
-
 
NC_011369  Rleg2_3667  binding-protein-dependent transport systems inner membrane component  37.1 
 
 
296 aa  123  6e-27  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_013169  Ksed_20470  carbohydrate ABC transporter membrane protein  33.64 
 
 
289 aa  122  9e-27  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0780045  normal  0.389193 
 
 
-
 
NC_011830  Dhaf_2632  binding-protein-dependent transport systems inner membrane component  34.22 
 
 
281 aa  121  1.9999999999999998e-26  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2701  binding-protein-dependent transport systems inner membrane component  33.2 
 
 
275 aa  120  4.9999999999999996e-26  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.0563997  n/a   
 
 
-
 
NC_009708  YpsIP31758_0916  ABC maltose/maltodextrin transporter, permease subunit  30.8 
 
 
283 aa  119  7e-26  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  0.402937  n/a   
 
 
-
 
NC_010465  YPK_0971  binding-protein-dependent transport systems inner membrane component  30.8 
 
 
283 aa  119  7e-26  Yersinia pseudotuberculosis YPIII  Bacteria  normal  0.0960519  n/a   
 
 
-
 
NC_010159  YpAngola_A3885  maltose/maltodextrin ABC transporter permease  30.8 
 
 
283 aa  119  7e-26  Yersinia pestis Angola  Bacteria  normal  normal  0.321948 
 
 
-
 
NC_013743  Htur_2651  binding-protein-dependent transport systems inner membrane component  37.5 
 
 
297 aa  119  9e-26  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009667  Oant_0311  binding-protein-dependent transport systems inner membrane component  30.66 
 
 
292 aa  118  9.999999999999999e-26  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.466995  n/a   
 
 
-
 
NC_009952  Dshi_3142  sugar ABC transporter  30.96 
 
 
275 aa  117  1.9999999999999998e-25  Dinoroseobacter shibae DFL 12  Bacteria  normal  0.367291  normal 
 
 
-
 
NC_013421  Pecwa_1319  binding-protein-dependent transport systems inner membrane component  31.22 
 
 
282 aa  117  3e-25  Pectobacterium wasabiae WPP163  Bacteria  normal  0.0499558  n/a   
 
 
-
 
NC_012917  PC1_2960  binding-protein-dependent transport systems inner membrane component  30.8 
 
 
282 aa  117  3e-25  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.0179548  n/a   
 
 
-
 
NC_009636  Smed_2697  binding-protein-dependent transport systems inner membrane component  32.13 
 
 
293 aa  117  3e-25  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_2609  binding-protein-dependent transport systems inner membrane component  33.67 
 
 
272 aa  116  5e-25  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.139734  normal 
 
 
-
 
NC_013093  Amir_0401  binding-protein-dependent transport systems inner membrane component  31.97 
 
 
273 aa  116  6e-25  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_004310  BR0237  sugar ABC transporter, permease protein  29.25 
 
 
291 aa  115  7.999999999999999e-25  Brucella suis 1330  Bacteria  normal  0.963709  n/a   
 
 
-
 
NC_009505  BOV_0230  sugar ABC transporter, permease protein  29.25 
 
 
291 aa  115  7.999999999999999e-25  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_007484  Noc_0280  ABC transporter, inner membrane subunit  32.24 
 
 
280 aa  115  1.0000000000000001e-24  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.787211  n/a   
 
 
-
 
NC_011899  Hore_20450  binding-protein-dependent transport systems inner membrane component  30.33 
 
 
277 aa  115  1.0000000000000001e-24  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.00000244229  n/a   
 
 
-
 
NC_013947  Snas_1043  binding-protein-dependent transport systems inner membrane component  28.98 
 
 
273 aa  115  1.0000000000000001e-24  Stackebrandtia nassauensis DSM 44728  Bacteria  decreased coverage  0.00118636  normal  0.712976 
 
 
-
 
NC_007802  Jann_4088  binding-protein-dependent transport systems inner membrane component  28.62 
 
 
275 aa  114  2.0000000000000002e-24  Jannaschia sp. CCS1  Bacteria  normal  normal  0.350213 
 
 
-
 
NC_010676  Bphyt_5636  binding-protein-dependent transport systems inner membrane component  31.4 
 
 
317 aa  114  2.0000000000000002e-24  Burkholderia phytofirmans PsJN  Bacteria  normal  0.330167  normal 
 
 
-
 
NC_013172  Bfae_25430  carbohydrate ABC transporter membrane protein  34.62 
 
 
275 aa  114  3e-24  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0542318  n/a   
 
 
-
 
NC_009565  TBFG_11262  sugar-transport integral membrane protein ABC transporter sugB  32.24 
 
 
274 aa  113  4.0000000000000004e-24  Mycobacterium tuberculosis F11  Bacteria  normal  hitchhiker  0.00203297 
 
 
-
 
NC_013174  Jden_0236  binding-protein-dependent transport systems inner membrane component  32.72 
 
 
271 aa  113  4.0000000000000004e-24  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_1183  binding-protein-dependent transport systems inner membrane component  30 
 
 
297 aa  113  6e-24  Thermoanaerobacter sp. X514  Bacteria  normal  0.275002  n/a   
 
 
-
 
NC_010320  Teth514_0395  binding-protein-dependent transport systems inner membrane component  31.73 
 
 
277 aa  112  8.000000000000001e-24  Thermoanaerobacter sp. X514  Bacteria  normal  0.230637  n/a   
 
 
-
 
NC_012793  GWCH70_0703  binding-protein-dependent transport systems inner membrane component  32.52 
 
 
289 aa  112  8.000000000000001e-24  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_012912  Dd1591_1278  binding-protein-dependent transport systems inner membrane component  29.6 
 
 
299 aa  112  9e-24  Dickeya zeae Ech1591  Bacteria  decreased coverage  0.000378819  n/a   
 
 
-
 
NC_013093  Amir_0809  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
281 aa  112  1.0000000000000001e-23  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_4134  ABC sugar transporter, inner membrane subunit  29.81 
 
 
295 aa  111  2.0000000000000002e-23  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_010625  Bphy_6369  binding-protein-dependent transport systems inner membrane component  31.22 
 
 
317 aa  111  2.0000000000000002e-23  Burkholderia phymatum STM815  Bacteria  normal  0.568723  normal 
 
 
-
 
NC_013131  Caci_6902  binding-protein-dependent transport systems inner membrane component  30.58 
 
 
271 aa  111  2.0000000000000002e-23  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0156181  normal  0.0353896 
 
 
-
 
NC_013093  Amir_2834  binding-protein-dependent transport systems inner membrane component  33.68 
 
 
275 aa  111  2.0000000000000002e-23  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_012850  Rleg_2428  binding-protein-dependent transport systems inner membrane component  31.22 
 
 
317 aa  111  2.0000000000000002e-23  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.443713  normal  0.627473 
 
 
-
 
NC_013530  Xcel_1047  binding-protein-dependent transport systems inner membrane component  32.07 
 
 
303 aa  111  2.0000000000000002e-23  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.0846293  n/a   
 
 
-
 
NC_013202  Hmuk_0942  binding-protein-dependent transport systems inner membrane component  30.92 
 
 
280 aa  111  2.0000000000000002e-23  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal  0.41482 
 
 
-
 
NC_009921  Franean1_4615  binding-protein-dependent transport systems inner membrane component  28.16 
 
 
295 aa  111  2.0000000000000002e-23  Frankia sp. EAN1pec  Bacteria  normal  0.60944  normal 
 
 
-
 
NC_012848  Rleg_4709  binding-protein-dependent transport systems inner membrane component  30.86 
 
 
278 aa  110  3e-23  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_011145  AnaeK_4265  binding-protein-dependent transport systems inner membrane component  29.81 
 
 
293 aa  110  4.0000000000000004e-23  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_0701  binding-protein-dependent transport systems inner membrane component  31.22 
 
 
315 aa  110  4.0000000000000004e-23  Polaromonas sp. JS666  Bacteria  normal  0.338666  normal 
 
 
-
 
NC_008541  Arth_3685  binding-protein-dependent transport systems inner membrane component  32.56 
 
 
299 aa  110  4.0000000000000004e-23  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_1513  binding-protein-dependent transport systems inner membrane component  32.04 
 
 
280 aa  110  4.0000000000000004e-23  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009487  SaurJH9_0201  binding-protein-dependent transport systems inner membrane component  30.67 
 
 
279 aa  110  4.0000000000000004e-23  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.990919  n/a   
 
 
-
 
NC_009620  Smed_4977  binding-protein-dependent transport systems inner membrane component  26.41 
 
 
288 aa  110  4.0000000000000004e-23  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.0547171 
 
 
-
 
NC_009632  SaurJH1_0207  binding-protein-dependent transport systems inner membrane component  30.67 
 
 
279 aa  110  4.0000000000000004e-23  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_4287  binding-protein-dependent transport systems inner membrane component  29.81 
 
 
293 aa  110  5e-23  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_014165  Tbis_1089  binding-protein-dependent transporter inner membrane component  32.38 
 
 
298 aa  110  5e-23  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.0183052 
 
 
-
 
NC_012848  Rleg_4987  binding-protein-dependent transport systems inner membrane component  29.91 
 
 
319 aa  110  5e-23  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_013172  Bfae_05730  carbohydrate ABC transporter membrane protein  34.27 
 
 
308 aa  110  5e-23  Brachybacterium faecium DSM 4810  Bacteria  normal  0.177084  n/a   
 
 
-
 
NC_012803  Mlut_04600  ABC-type sugar transport system, permease component  29.86 
 
 
295 aa  109  7.000000000000001e-23  Micrococcus luteus NCTC 2665  Bacteria  normal  0.539803  n/a   
 
 
-
 
NC_013172  Bfae_04120  ABC-type maltose transport systems, permease component  30.58 
 
 
305 aa  109  8.000000000000001e-23  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_012791  Vapar_3685  binding-protein-dependent transport systems inner membrane component  29.58 
 
 
283 aa  109  9.000000000000001e-23  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_009621  Smed_5860  binding-protein-dependent transport systems inner membrane component  31.55 
 
 
319 aa  109  9.000000000000001e-23  Sinorhizobium medicae WSM419  Bacteria  normal  0.235146  normal 
 
 
-
 
NC_009664  Krad_1115  binding-protein-dependent transport systems inner membrane component  30.48 
 
 
280 aa  109  9.000000000000001e-23  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal  0.565272 
 
 
-
 
NC_011899  Hore_03310  binding-protein-dependent transport systems inner membrane component  29.61 
 
 
288 aa  108  1e-22  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_2016  binding-protein-dependent transport systems inner membrane component  29.49 
 
 
281 aa  108  1e-22  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.461733  normal 
 
 
-
 
NC_013174  Jden_1525  binding-protein-dependent transport systems inner membrane component  32.1 
 
 
300 aa  108  1e-22  Jonesia denitrificans DSM 20603  Bacteria  normal  0.537568  normal  0.817289 
 
 
-
 
NC_012669  Bcav_1097  binding-protein-dependent transport systems inner membrane component  27.86 
 
 
280 aa  108  1e-22  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.248821  normal 
 
 
-
 
NC_011831  Cagg_0404  binding-protein-dependent transport systems inner membrane component  29.44 
 
 
281 aa  107  2e-22  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_5669  binding-protein-dependent transport systems inner membrane component  31.48 
 
 
275 aa  108  2e-22  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_0399  binding-protein-dependent transport systems inner membrane component  33.8 
 
 
286 aa  108  2e-22  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_008786  Veis_1241  binding-protein-dependent transport systems inner membrane component  31.92 
 
 
283 aa  108  2e-22  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_009636  Smed_2144  binding-protein-dependent transport systems inner membrane component  29.95 
 
 
288 aa  107  2e-22  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B0078  ABC sugar transporter, inner membrane subunit  30.89 
 
 
293 aa  107  3e-22  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_1845  binding-protein-dependent transport systems inner membrane component  32.42 
 
 
295 aa  107  3e-22  Actinosynnema mirum DSM 43827  Bacteria  normal  0.352716  n/a   
 
 
-
 
NC_007948  Bpro_3527  binding-protein-dependent transport systems inner membrane component  28.75 
 
 
283 aa  107  4e-22  Polaromonas sp. JS666  Bacteria  normal  0.16619  normal  0.170584 
 
 
-
 
NC_014151  Cfla_0962  binding-protein-dependent transport systems inner membrane component  28.16 
 
 
277 aa  107  4e-22  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0871909  hitchhiker  0.000355781 
 
 
-
 
NC_012791  Vapar_3350  binding-protein-dependent transport systems inner membrane component  31.09 
 
 
274 aa  107  4e-22  Variovorax paradoxus S110  Bacteria  normal  0.610127  n/a   
 
 
-
 
NC_014165  Tbis_1103  binding-protein-dependent transporter inner membrane component  35.05 
 
 
283 aa  107  4e-22  Thermobispora bispora DSM 43833  Bacteria  normal  0.216355  normal  0.105298 
 
 
-
 
NC_011661  Dtur_0710  binding-protein-dependent transport systems inner membrane component  32.23 
 
 
281 aa  107  4e-22  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.667982  n/a   
 
 
-
 
NC_013093  Amir_0448  binding-protein-dependent transport systems inner membrane component  36.41 
 
 
277 aa  107  5e-22  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_1418  binding-protein-dependent transport systems inner membrane component  30.12 
 
 
276 aa  106  6e-22  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_1818  binding-protein-dependent transport systems inner membrane component  27.39 
 
 
279 aa  106  6e-22  Thermosipho melanesiensis BI429  Bacteria  normal  0.675174  n/a   
 
 
-
 
NC_012793  GWCH70_0697  binding-protein-dependent transport systems inner membrane component  30.58 
 
 
280 aa  106  7e-22  Geobacillus sp. WCH70  Bacteria  normal  0.450208  n/a   
 
 
-
 
NC_009338  Mflv_3853  binding-protein-dependent transport systems inner membrane component  29.39 
 
 
275 aa  106  7e-22  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal  0.0623628 
 
 
-
 
NC_009636  Smed_0188  binding-protein-dependent transport systems inner membrane component  29.76 
 
 
277 aa  106  7e-22  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
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