64 homologs were found in PanDaTox collection
for query gene SERP2121 on replicon NC_002976
Organism: Staphylococcus epidermidis RP62A



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  81.37 
 
 		 425 aa  709    Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  100 
 
 		 425 aa  868    Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  81.37 
 
 		 425 aa  709    Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  46.79 
 
 		 410 aa  378  1e-103  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
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NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  45.32 
 
 		 423 aa  347  3e-94  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
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NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  46.06 
 
 		 427 aa  342  1e-92  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  41.77 
 
 		 406 aa  321  1.9999999999999998e-86  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  41.98 
 
 		 420 aa  318  2e-85  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  41.53 
 
 		 429 aa  307  3e-82  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  39.86 
 
 		 456 aa  305  1.0000000000000001e-81  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  42.65 
 
 		 428 aa  301  1e-80  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  41.2 
 
 		 428 aa  300  3e-80  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  39.57 
 
 		 444 aa  298  8e-80  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  40.96 
 
 		 428 aa  298  1e-79  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  40.62 
 
 		 419 aa  298  1e-79  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  39.33 
 
 		 441 aa  295  1e-78  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  40.57 
 
 		 440 aa  292  8e-78  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  41.16 
 
 		 428 aa  291  2e-77  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  40.48 
 
 		 420 aa  280  4e-74  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  40.95 
 
 		 401 aa  274  2.0000000000000002e-72  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  38.26 
 
 		 429 aa  261  2e-68  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.02 
 
 		 363 aa  260  3e-68  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013721  HMPREF0424_0360  hydroxymethylglutaryl-CoA reductase, degradative  36.94 
 
 		 444 aa  248  1e-64  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_013440  Hoch_3406  hydroxymethylglutaryl-CoA reductase, degradative  38.44 
 
 		 443 aa  248  1e-64  Haliangium ochraceum DSM 14365  Bacteria  normal  0.121756  normal  0.0808381 
 
 
-
 
NC_006369  lpl2030  hypothetical protein  34.57 
 
 		 432 aa  247  3e-64  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  33.87 
 
 		 432 aa  243  3e-63  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  37.91 
 
 		 418 aa  239  5e-62  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  35.07 
 
 		 436 aa  228  2e-58  Capnocytophaga ochracea DSM 7271  Bacteria  normal  1  n/a   
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  36.06 
 
 		 436 aa  225  1e-57  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  36.12 
 
 		 437 aa  221  1.9999999999999999e-56  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_013440  Hoch_5714  hydroxymethylglutaryl-CoA reductase, degradative  39.11 
 
 		 402 aa  215  9.999999999999999e-55  Haliangium ochraceum DSM 14365  Bacteria  normal  0.148177  normal  1 
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  33.77 
 
 		 422 aa  211  2e-53  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  26.47 
 
 		 1047 aa  78.2  0.0000000000003  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.8 
 
 		 409 aa  74.7  0.000000000003  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  25.14 
 
 		 1125 aa  69.3  0.0000000001  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  25.82 
 
 		 395 aa  66.2  0.000000001  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  23.75 
 
 		 1283 aa  65.5  0.000000002  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.93 
 
 		 403 aa  64.7  0.000000003  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  25.33 
 
 		 410 aa  63.2  0.000000009  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.63 
 
 		 410 aa  62  0.00000002  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  22.97 
 
 		 395 aa  61.2  0.00000004  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.07 
 
 		 418 aa  59.7  0.0000001  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  25.28 
 
 		 414 aa  58.5  0.0000002  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  26.05 
 
 		 403 aa  58.9  0.0000002  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.86 
 
 		 410 aa  57.8  0.0000004  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  23.16 
 
 		 395 aa  57.8  0.0000004  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  30 
 
 		 399 aa  56.6  0.0000008  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.06 
 
 		 408 aa  54.3  0.000004  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  27.86 
 
 		 514 aa  54.3  0.000004  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.53 
 
 		 408 aa  53.1  0.000009  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  27.22 
 
 		 399 aa  52.8  0.00001  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.97 
 
 		 408 aa  52  0.00002  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  26.76 
 
 		 418 aa  51.2  0.00003  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.17 
 
 		 411 aa  50.8  0.00004  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.53 
 
 		 398 aa  51.2  0.00004  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.5 
 
 		 408 aa  50.1  0.00008  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  23.64 
 
 		 420 aa  49.7  0.00009  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.18 
 
 		 364 aa  49.7  0.00009  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  23.45 
 
 		 420 aa  48.5  0.0002  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  22.22 
 
 		 396 aa  48.9  0.0002  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.04 
 
 		 407 aa  45.4  0.002  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  24.43 
 
 		 419 aa  44.7  0.003  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  24.26 
 
 		 416 aa  43.5  0.008  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  25.3 
 
 		 367 aa  43.1  0.01  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
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