61 homologs were found in PanDaTox collection
for query gene MmarC6_0860 on replicon NC_009975
Organism: Methanococcus maripaludis C6



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  100 
 
 		 408 aa  826    Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  98.53 
 
 		 408 aa  816    Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  97.79 
 
 		 408 aa  813    Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  86.14 
 
 		 411 aa  723    Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  73.09 
 
 		 418 aa  606  9.999999999999999e-173  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  51.84 
 
 		 401 aa  396  1e-109  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  50.38 
 
 		 395 aa  390  1e-107  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  49.39 
 
 		 403 aa  389  1e-107  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  51.6 
 
 		 404 aa  387  1e-106  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  52.53 
 
 		 414 aa  387  1e-106  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.14 
 
 		 398 aa  382  1e-105  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  49.51 
 
 		 409 aa  383  1e-105  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  50.37 
 
 		 407 aa  381  1e-104  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  48.53 
 
 		 403 aa  374  1e-102  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  50.63 
 
 		 399 aa  367  1e-100  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  49.38 
 
 		 426 aa  365  1e-100  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  51.64 
 
 		 399 aa  367  1e-100  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  50.86 
 
 		 418 aa  367  1e-100  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  49.02 
 
 		 410 aa  361  1e-98  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  48.18 
 
 		 408 aa  358  8e-98  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  49.14 
 
 		 402 aa  355  5.999999999999999e-97  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  46.25 
 
 		 410 aa  349  5e-95  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  46.94 
 
 		 410 aa  347  3e-94  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  49.14 
 
 		 407 aa  335  7e-91  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  43.23 
 
 		 1283 aa  294  2e-78  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  42.37 
 
 		 395 aa  288  9e-77  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  42.51 
 
 		 419 aa  280  3e-74  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  44.06 
 
 		 420 aa  278  1e-73  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  40.48 
 
 		 396 aa  275  7e-73  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  40.98 
 
 		 420 aa  275  8e-73  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  40.91 
 
 		 1047 aa  275  1.0000000000000001e-72  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  40.69 
 
 		 420 aa  267  2.9999999999999995e-70  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  42.82 
 
 		 514 aa  265  1e-69  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  42.27 
 
 		 1125 aa  262  6.999999999999999e-69  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  45.88 
 
 		 367 aa  256  5e-67  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  41.2 
 
 		 416 aa  255  1.0000000000000001e-66  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  38.77 
 
 		 424 aa  231  1e-59  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_009727  CBUD_0622  3-hydroxy-3-methylglutaryl-coenzyme A reductase  41.16 
 
 		 357 aa  220  3e-56  Coxiella burnetii Dugway 5J108-111  Bacteria  hitchhiker  0.000221084  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0723  hydroxymethylglutaryl-CoA reductase (NADPH)  41.16 
 
 		 355 aa  220  3e-56  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.000000000015079  n/a   
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  38.3 
 
 		 352 aa  212  1e-53  Thiomicrospira crunogena XCL-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  34.17 
 
 		 395 aa  194  3e-48  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  29.05 
 
 		 364 aa  161  2e-38  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  29 
 
 		 406 aa  61.6  0.00000002  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  24.44 
 
 		 410 aa  57  0.0000005  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  25.72 
 
 		 419 aa  55.5  0.000002  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  23.06 
 
 		 425 aa  54.3  0.000004  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  24.8 
 
 		 429 aa  52.4  0.00001  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  26.75 
 
 		 428 aa  50.1  0.00007  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  24.07 
 
 		 437 aa  49.7  0.00009  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  22.19 
 
 		 425 aa  49.3  0.0001  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  27.54 
 
 		 422 aa  49.7  0.0001  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  22.19 
 
 		 425 aa  49.3  0.0001  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  23.51 
 
 		 441 aa  48.5  0.0002  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  24.59 
 
 		 401 aa  47.8  0.0003  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  23.3 
 
 		 429 aa  48.1  0.0003  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  24.73 
 
 		 427 aa  48.1  0.0003  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  21.88 
 
 		 420 aa  45.8  0.001  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  24.26 
 
 		 428 aa  45.1  0.002  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  24.21 
 
 		 363 aa  45.1  0.002  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.66 
 
 		 436 aa  45.4  0.002  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  23.67 
 
 		 444 aa  43.5  0.006  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
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