57 homologs were found in PanDaTox collection
for query gene MADE_03398 on replicon NC_011138
Organism: Alteromonas macleodii 'Deep ecotype'



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  100 
 
 		 396 aa  831    Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  60.31 
 
 		 395 aa  521  1e-146  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  55.06 
 
 		 514 aa  412  1e-114  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  43.92 
 
 		 395 aa  308  8e-83  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  42.4 
 
 		 409 aa  292  8e-78  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  42.36 
 
 		 411 aa  289  6e-77  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  40.68 
 
 		 418 aa  286  2.9999999999999996e-76  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  42.71 
 
 		 410 aa  276  3e-73  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  40.48 
 
 		 408 aa  276  4e-73  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  40.75 
 
 		 408 aa  276  5e-73  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  44.03 
 
 		 398 aa  276  5e-73  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  40.48 
 
 		 408 aa  275  7e-73  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  45.12 
 
 		 399 aa  272  7e-72  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  44 
 
 		 410 aa  271  1e-71  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  42.59 
 
 		 399 aa  265  1e-69  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  39.25 
 
 		 403 aa  264  2e-69  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  42.4 
 
 		 420 aa  262  6.999999999999999e-69  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  41.28 
 
 		 420 aa  262  8e-69  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  41.15 
 
 		 408 aa  261  1e-68  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  40.75 
 
 		 424 aa  260  2e-68  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  41.35 
 
 		 420 aa  260  3e-68  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  42.18 
 
 		 419 aa  258  1e-67  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  39.21 
 
 		 410 aa  252  8.000000000000001e-66  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  38.77 
 
 		 414 aa  243  3e-63  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  39.31 
 
 		 404 aa  241  2e-62  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  38.61 
 
 		 403 aa  240  2.9999999999999997e-62  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  39.47 
 
 		 426 aa  239  8e-62  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  40.11 
 
 		 401 aa  238  1e-61  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  42.02 
 
 		 407 aa  235  8e-61  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  39.74 
 
 		 418 aa  234  3e-60  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  40.43 
 
 		 402 aa  220  3e-56  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  39.35 
 
 		 407 aa  217  2.9999999999999998e-55  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  32.74 
 
 		 395 aa  206  5e-52  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  39.25 
 
 		 367 aa  205  1e-51  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  35.36 
 
 		 352 aa  202  9e-51  Thiomicrospira crunogena XCL-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  34.72 
 
 		 1283 aa  201  1.9999999999999998e-50  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_009727  CBUD_0622  3-hydroxy-3-methylglutaryl-coenzyme A reductase  35.29 
 
 		 357 aa  192  8e-48  Coxiella burnetii Dugway 5J108-111  Bacteria  hitchhiker  0.000221084  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0723  hydroxymethylglutaryl-CoA reductase (NADPH)  35.29 
 
 		 355 aa  192  9e-48  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.000000000015079  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  36.21 
 
 		 1047 aa  191  2e-47  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  36.26 
 
 		 1125 aa  186  5e-46  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  30.43 
 
 		 364 aa  176  5e-43  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  35.82 
 
 		 416 aa  172  6.999999999999999e-42  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  25.15 
 
 		 419 aa  65.1  0.000000002  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.7 
 
 		 410 aa  52.8  0.00001  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  23.12 
 
 		 432 aa  52.8  0.00001  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  23.19 
 
 		 440 aa  52  0.00002  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  21.43 
 
 		 429 aa  52  0.00002  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_006369  lpl2030  hypothetical protein  23.12 
 
 		 432 aa  51.6  0.00002  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  22.22 
 
 		 425 aa  48.9  0.0002  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  35.48 
 
 		 429 aa  45.8  0.001  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  20.98 
 
 		 456 aa  45.4  0.002  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  21.65 
 
 		 406 aa  45.4  0.002  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  22.87 
 
 		 420 aa  45.1  0.002  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  21.37 
 
 		 444 aa  45.1  0.003  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  24.27 
 
 		 437 aa  44.7  0.003  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  34.29 
 
 		 428 aa  43.1  0.008  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  34.29 
 
 		 428 aa  43.1  0.008  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
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