62 homologs were found in PanDaTox collection
for query gene LACR_1664 on replicon NC_008527
Organism: Lactococcus lactis subsp. cremoris SK11



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  100 
 
 		 410 aa  827    Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  47.03 
 
 		 425 aa  379  1e-104  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  47.03 
 
 		 425 aa  379  1e-104  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  46.79 
 
 		 425 aa  378  1e-103  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  47.32 
 
 		 401 aa  352  5.9999999999999994e-96  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.27 
 
 		 420 aa  343  2e-93  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.54 
 
 		 423 aa  338  9.999999999999999e-92  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  45.08 
 
 		 427 aa  330  3e-89  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  42.48 
 
 		 444 aa  324  2e-87  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  42 
 
 		 456 aa  323  5e-87  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  44.14 
 
 		 406 aa  322  6e-87  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  42.45 
 
 		 419 aa  315  8e-85  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  41.37 
 
 		 440 aa  299  5e-80  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  39.95 
 
 		 429 aa  298  1e-79  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  39.76 
 
 		 441 aa  294  2e-78  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  41.83 
 
 		 420 aa  293  5e-78  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  39.47 
 
 		 428 aa  285  9e-76  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_013440  Hoch_3406  hydroxymethylglutaryl-CoA reductase, degradative  39.47 
 
 		 443 aa  281  1e-74  Haliangium ochraceum DSM 14365  Bacteria  normal  0.121756  normal  0.0808381 
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  42.34 
 
 		 428 aa  280  4e-74  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_006369  lpl2030  hypothetical protein  37.29 
 
 		 432 aa  268  2e-70  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  37.05 
 
 		 432 aa  268  2e-70  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  40.21 
 
 		 363 aa  266  4e-70  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  39.79 
 
 		 436 aa  266  5.999999999999999e-70  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  37.5 
 
 		 428 aa  265  1e-69  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  37.26 
 
 		 428 aa  263  4e-69  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  38.65 
 
 		 429 aa  259  6e-68  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_013721  HMPREF0424_0360  hydroxymethylglutaryl-CoA reductase, degradative  39.36 
 
 		 444 aa  255  1.0000000000000001e-66  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  41.39 
 
 		 418 aa  248  1e-64  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  37.82 
 
 		 436 aa  241  2e-62  Capnocytophaga ochracea DSM 7271  Bacteria  normal  1  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  35.63 
 
 		 437 aa  240  4e-62  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_013440  Hoch_5714  hydroxymethylglutaryl-CoA reductase, degradative  40.32 
 
 		 402 aa  224  3e-57  Haliangium ochraceum DSM 14365  Bacteria  normal  0.148177  normal  1 
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  37.26 
 
 		 422 aa  207  2e-52  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.8 
 
 		 409 aa  70.9  0.00000000004  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.32 
 
 		 403 aa  67  0.0000000005  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  23.42 
 
 		 1283 aa  65.9  0.000000001  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  25 
 
 		 1125 aa  64.3  0.000000004  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  25.41 
 
 		 403 aa  61.6  0.00000002  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  23.98 
 
 		 424 aa  61.2  0.00000003  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  23.33 
 
 		 395 aa  58.9  0.0000002  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.1 
 
 		 418 aa  57.8  0.0000004  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.44 
 
 		 408 aa  57  0.0000005  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.46 
 
 		 395 aa  56.6  0.0000008  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.2 
 
 		 408 aa  53.5  0.000006  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.97 
 
 		 411 aa  53.1  0.000008  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  21.62 
 
 		 1047 aa  52.8  0.00001  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  27.54 
 
 		 402 aa  52.4  0.00001  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  22.7 
 
 		 396 aa  52.8  0.00001  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.81 
 
 		 408 aa  52.8  0.00001  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  24.63 
 
 		 514 aa  51.6  0.00002  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  25.88 
 
 		 399 aa  51.6  0.00003  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.8 
 
 		 410 aa  51.2  0.00003  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.15 
 
 		 399 aa  50.8  0.00004  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  23.95 
 
 		 418 aa  50.4  0.00005  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.68 
 
 		 408 aa  50.4  0.00005  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  28.48 
 
 		 414 aa  49.7  0.00009  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.31 
 
 		 407 aa  48.5  0.0002  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  23.16 
 
 		 395 aa  48.5  0.0002  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.59 
 
 		 398 aa  48.9  0.0002  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.18 
 
 		 407 aa  44.7  0.003  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.08 
 
 		 401 aa  44.3  0.004  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  21.84 
 
 		 364 aa  43.9  0.005  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  25.17 
 
 		 426 aa  43.9  0.006  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
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