60 homologs were found in PanDaTox collection
for query gene RoseRS_0431 on replicon NC_009523
Organism: Roseiflexus sp. RS-1



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  100 
 
 		 456 aa  918    Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  94.41 
 
 		 444 aa  823    Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  73.77 
 
 		 441 aa  645    Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  80.61 
 
 		 440 aa  694    Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  59.76 
 
 		 429 aa  507  9.999999999999999e-143  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  60.14 
 
 		 428 aa  507  9.999999999999999e-143  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  58.35 
 
 		 420 aa  487  1e-136  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  58.81 
 
 		 428 aa  481  1e-134  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  59.05 
 
 		 428 aa  481  1e-134  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  56.97 
 
 		 419 aa  472  1e-132  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  54.44 
 
 		 428 aa  442  1e-123  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  50 
 
 		 418 aa  390  1e-107  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_013440  Hoch_3406  hydroxymethylglutaryl-CoA reductase, degradative  52.37 
 
 		 443 aa  384  1e-105  Haliangium ochraceum DSM 14365  Bacteria  normal  0.121756  normal  0.0808381 
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  43.07 
 
 		 406 aa  346  5e-94  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_006369  lpl2030  hypothetical protein  42.07 
 
 		 432 aa  330  4e-89  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  41.61 
 
 		 432 aa  327  2.0000000000000001e-88  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  42 
 
 		 410 aa  323  5e-87  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  40.95 
 
 		 427 aa  307  3e-82  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  41.33 
 
 		 423 aa  306  6e-82  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  39.86 
 
 		 425 aa  305  1.0000000000000001e-81  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_013440  Hoch_5714  hydroxymethylglutaryl-CoA reductase, degradative  49.49 
 
 		 402 aa  301  2e-80  Haliangium ochraceum DSM 14365  Bacteria  normal  0.148177  normal  1 
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  41.47 
 
 		 420 aa  296  7e-79  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  39.57 
 
 		 425 aa  294  2e-78  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  39.57 
 
 		 425 aa  294  2e-78  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  37.62 
 
 		 401 aa  253  6e-66  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  38.19 
 
 		 436 aa  252  9.000000000000001e-66  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  37.77 
 
 		 437 aa  247  3e-64  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  36.49 
 
 		 429 aa  239  1e-61  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  38.46 
 
 		 436 aa  233  4.0000000000000004e-60  Capnocytophaga ochracea DSM 7271  Bacteria  normal  1  n/a   
 
 
-
 
NC_013721  HMPREF0424_0360  hydroxymethylglutaryl-CoA reductase, degradative  34.6 
 
 		 444 aa  210  4e-53  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  34.97 
 
 		 363 aa  209  8e-53  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  33.33 
 
 		 422 aa  195  1e-48  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  27.12 
 
 		 1125 aa  71.2  0.00000000004  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.67 
 
 		 409 aa  67.4  0.0000000005  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  26.1 
 
 		 403 aa  65.1  0.000000002  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  26.16 
 
 		 1047 aa  64.3  0.000000004  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  27.13 
 
 		 395 aa  63.9  0.000000005  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  26.2 
 
 		 410 aa  62  0.00000002  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  25 
 
 		 426 aa  60.8  0.00000005  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  25.62 
 
 		 1283 aa  56.6  0.000001  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  21.83 
 
 		 424 aa  56.6  0.000001  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  25.43 
 
 		 367 aa  55.5  0.000002  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.95 
 
 		 410 aa  54.7  0.000003  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  25.07 
 
 		 408 aa  52.8  0.00001  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  25.62 
 
 		 420 aa  52  0.00002  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.43 
 
 		 401 aa  49.3  0.0001  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.24 
 
 		 402 aa  48.9  0.0002  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.39 
 
 		 407 aa  48.5  0.0002  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.7 
 
 		 418 aa  49.3  0.0002  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  22.95 
 
 		 419 aa  48.1  0.0003  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  24.38 
 
 		 420 aa  47.8  0.0004  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.73 
 
 		 404 aa  46.6  0.0008  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.53 
 
 		 414 aa  45.8  0.002  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  25.56 
 
 		 418 aa  45.4  0.002  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  20.98 
 
 		 396 aa  45.4  0.002  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.42 
 
 		 410 aa  45.8  0.002  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  25.47 
 
 		 399 aa  45.1  0.003  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.74 
 
 		 399 aa  43.9  0.006  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  24.93 
 
 		 420 aa  43.9  0.006  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.87 
 
 		 411 aa  43.5  0.007  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
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