77 homologs were found in PanDaTox collection
for query gene Pars_0796 on replicon NC_009376
Organism: Pyrobaculum arsenaticum DSM 13514



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  83.8 
 
 
399 aa  660    Pyrobaculum islandicum DSM 4184  Archaea  normal  hitchhiker  0.00207544 
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  100 
 
 
398 aa  802    Pyrobaculum arsenaticum DSM 13514  Archaea  normal  normal 
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  89.03 
 
 
399 aa  683    Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  85.57 
 
 
395 aa  699    Thermoproteus neutrophilus V24Sta  Archaea  normal  normal 
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  67.93 
 
 
410 aa  536  1e-151  Caldivirga maquilingensis IC-167  Archaea  normal  normal 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  59.85 
 
 
409 aa  472  1e-132  Sulfolobus solfataricus 98/2  Archaea  normal  n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  61.62 
 
 
410 aa  454  1e-127  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal 
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.14 
 
 
408 aa  408  1e-113  Methanococcus maripaludis C7  Archaea  normal  normal 
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  51.89 
 
 
408 aa  405  1.0000000000000001e-112  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.39 
 
 
411 aa  407  1.0000000000000001e-112  Methanococcus vannielii SB  Archaea  normal  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  51.01 
 
 
418 aa  405  1.0000000000000001e-112  Methanococcus aeolicus Nankai-3  Archaea  normal  n/a   
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.14 
 
 
408 aa  407  1.0000000000000001e-112  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  56.12 
 
 
403 aa  405  1.0000000000000001e-112  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal 
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  54.73 
 
 
401 aa  398  1e-109  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  55.16 
 
 
408 aa  388  1e-107  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  53.16 
 
 
404 aa  386  1e-106  Methanocorpusculum labreanum Z  Archaea  normal  hitchhiker  0.0000342006 
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  53.06 
 
 
403 aa  386  1e-106  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  54.22 
 
 
407 aa  384  1e-105  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.79 
 
 
426 aa  383  1e-105  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal 
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  52.14 
 
 
410 aa  369  1e-101  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  55.87 
 
 
402 aa  366  1e-100  Methanoculleus marisnigri JR1  Archaea  normal  n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  54.18 
 
 
414 aa  364  1e-99  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  53 
 
 
418 aa  363  3e-99  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  52.16 
 
 
407 aa  327  3e-88  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  normal  0.439309 
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  51.69 
 
 
367 aa  314  1.9999999999999998e-84  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  n/a   
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  44.03 
 
 
396 aa  298  1e-79  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  43.89 
 
 
1047 aa  296  4e-79  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  normal 
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  43.56 
 
 
395 aa  292  9e-78  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  43.29 
 
 
1283 aa  287  2e-76  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  44.78 
 
 
420 aa  277  2e-73  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  46.63 
 
 
1125 aa  273  4.0000000000000004e-72  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal 
 
 
-
 
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  47.85 
 
 
420 aa  272  7e-72  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  44.33 
 
 
416 aa  272  7e-72  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal 
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  48.55 
 
 
420 aa  270  2.9999999999999997e-71  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  45.83 
 
 
419 aa  263  4e-69  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  44.57 
 
 
424 aa  261  1e-68  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  43.47 
 
 
514 aa  257  2e-67  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0723  hydroxymethylglutaryl-CoA reductase (NADPH)  42.44 
 
 
355 aa  229  5e-59  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.000000000015079  n/a   
 
 
-
 
NC_009727  CBUD_0622  3-hydroxy-3-methylglutaryl-coenzyme A reductase  42.44 
 
 
357 aa  229  6e-59  Coxiella burnetii Dugway 5J108-111  Bacteria  hitchhiker  0.000221084  n/a   
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  39.47 
 
 
352 aa  223  6e-57  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  32.99 
 
 
395 aa  208  2e-52  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  30.67 
 
 
364 aa  172  9e-42  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  23.96 
 
 
429 aa  74.7  0.000000000003  Lactobacillus gasseri ATCC 33323  Bacteria  normal  hitchhiker  0.0000000000375721 
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  26.42 
 
 
425 aa  63.9  0.000000004  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_006369  lpl2030  hypothetical protein  24.4 
 
 
432 aa  63.5  0.000000006  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.9 
 
 
410 aa  62.8  0.00000001  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  24.14 
 
 
432 aa  62.4  0.00000001  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  26.36 
 
 
444 aa  61.2  0.00000003  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  25.38 
 
 
419 aa  60.5  0.00000005  Methanosaeta thermophila PT  Archaea  normal  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  23.08 
 
 
406 aa  58.2  0.0000003  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.65 
 
 
423 aa  57  0.0000006  Streptococcus thermophilus LMD-9  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  25.75 
 
 
456 aa  56.6  0.0000007  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.316381 
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  26.58 
 
 
425 aa  56.2  0.000001  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  26.58 
 
 
425 aa  56.2  0.000001  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  25.54 
 
 
437 aa  54.7  0.000003  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  24.51 
 
 
401 aa  54.3  0.000004  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  24 
 
 
440 aa  54.3  0.000004  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.00353445 
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.36 
 
 
420 aa  54.3  0.000004  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  25.27 
 
 
429 aa  50.8  0.00004  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  24.94 
 
 
436 aa  50.1  0.00007  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  25.56 
 
 
428 aa  50.1  0.00007  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  25.21 
 
 
428 aa  49.7  0.0001  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.316182 
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  25.2 
 
 
420 aa  49.7  0.0001  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  24.03 
 
 
441 aa  48.5  0.0002  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  24.59 
 
 
436 aa  47.4  0.0005  Capnocytophaga ochracea DSM 7271  Bacteria  normal  n/a   
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.97 
 
 
363 aa  46.2  0.0009  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_007435  BURPS1710b_A2482  hypothetical protein  29.59 
 
 
273 aa  45.8  0.001  Burkholderia pseudomallei 1710b  Bacteria  normal  n/a   
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  23.42 
 
 
428 aa  45.8  0.001  Thermofilum pendens Hrk 5  Archaea  normal  n/a   
 
 
-
 
NC_008784  BMASAVP1_0333  hypothetical protein  29.59 
 
 
282 aa  46.2  0.001  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_006349  BMAA1348  hypothetical protein  29.59 
 
 
273 aa  45.8  0.001  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_0611  hypothetical protein  29.59 
 
 
282 aa  46.2  0.001  Burkholderia mallei NCTC 10229  Bacteria  normal  n/a   
 
 
-
 
NC_009075  BURPS668_A1291  hypothetical protein  29.59 
 
 
282 aa  45.8  0.001  Burkholderia pseudomallei 668  Bacteria  normal  0.132365  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1219  hypothetical protein  29.59 
 
 
282 aa  45.8  0.001  Burkholderia pseudomallei 1106a  Bacteria  normal  0.264003  n/a   
 
 
-
 
NC_009079  BMA10247_A0958  hypothetical protein  29.59 
 
 
282 aa  46.2  0.001  Burkholderia mallei NCTC 10247  Bacteria  normal  n/a   
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  26.22 
 
 
422 aa  45.1  0.002  Borrelia burgdorferi ZS7  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  22.86 
 
 
427 aa  44.3  0.004  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_007650  BTH_II1513  hypothetical protein  28.24 
 
 
270 aa  43.9  0.005  Burkholderia thailandensis E264  Bacteria  normal  0.175272  n/a   
 
 
-
 
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