58 homologs were found in PanDaTox collection
for query gene Mevan_1099 on replicon NC_009634
Organism: Methanococcus vannielii SB



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  85.15 
 
 		 408 aa  719    Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
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NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  86.14 
 
 		 408 aa  723    Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  100 
 
 		 411 aa  829    Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
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NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  86.14 
 
 		 408 aa  723    Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
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NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  72.84 
 
 		 418 aa  604  9.999999999999999e-173  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
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NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  53.56 
 
 		 404 aa  397  1e-109  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.33 
 
 		 401 aa  397  1e-109  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  50.63 
 
 		 395 aa  392  1e-108  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  50.86 
 
 		 407 aa  388  1e-107  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  54.28 
 
 		 414 aa  390  1e-107  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  49.63 
 
 		 403 aa  390  1e-107  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  52.39 
 
 		 398 aa  382  1e-105  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  48.28 
 
 		 403 aa  373  1e-102  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  47.56 
 
 		 409 aa  373  1e-102  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  51.35 
 
 		 418 aa  369  1e-101  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  49.38 
 
 		 426 aa  371  1e-101  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  53.15 
 
 		 399 aa  368  1e-100  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  51.13 
 
 		 399 aa  366  1e-100  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  49.63 
 
 		 402 aa  362  5.0000000000000005e-99  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  47.46 
 
 		 408 aa  356  3.9999999999999996e-97  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  47.3 
 
 		 410 aa  348  1e-94  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  45.48 
 
 		 410 aa  347  3e-94  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  47.2 
 
 		 410 aa  342  7e-93  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  47.9 
 
 		 407 aa  333  3e-90  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  41.84 
 
 		 395 aa  290  3e-77  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  42.36 
 
 		 396 aa  289  6e-77  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  43.88 
 
 		 419 aa  283  4.0000000000000003e-75  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  40.62 
 
 		 1283 aa  281  2e-74  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  40.77 
 
 		 1047 aa  278  9e-74  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  41.97 
 
 		 420 aa  275  1.0000000000000001e-72  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  40.92 
 
 		 420 aa  273  3e-72  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  40.05 
 
 		 1125 aa  264  2e-69  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  45.58 
 
 		 367 aa  262  8.999999999999999e-69  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  43.19 
 
 		 514 aa  260  3e-68  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  40.24 
 
 		 416 aa  260  4e-68  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  41.82 
 
 		 420 aa  257  2e-67  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  36.65 
 
 		 424 aa  225  9e-58  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0723  hydroxymethylglutaryl-CoA reductase (NADPH)  40.99 
 
 		 355 aa  216  9e-55  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.000000000015079  n/a   
 
 
-
 
NC_009727  CBUD_0622  3-hydroxy-3-methylglutaryl-coenzyme A reductase  40.99 
 
 		 357 aa  215  9.999999999999999e-55  Coxiella burnetii Dugway 5J108-111  Bacteria  hitchhiker  0.000221084  n/a   
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  36.68 
 
 		 352 aa  202  9.999999999999999e-51  Thiomicrospira crunogena XCL-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  32.4 
 
 		 395 aa  192  1e-47  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  29.59 
 
 		 364 aa  162  1e-38  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  28.11 
 
 		 406 aa  62.8  0.00000001  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  24.42 
 
 		 437 aa  56.6  0.0000007  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  23.56 
 
 		 419 aa  54.3  0.000004  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.97 
 
 		 410 aa  53.1  0.000008  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  23.17 
 
 		 425 aa  50.8  0.00004  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  23.41 
 
 		 429 aa  47.8  0.0003  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  22.98 
 
 		 425 aa  47  0.0006  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  22.98 
 
 		 425 aa  47  0.0006  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  24.24 
 
 		 427 aa  46.6  0.0007  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  23.75 
 
 		 428 aa  45.4  0.002  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  23.2 
 
 		 401 aa  45.4  0.002  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  23.06 
 
 		 444 aa  45.4  0.002  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  26.83 
 
 		 422 aa  44.3  0.004  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  24.79 
 
 		 423 aa  43.9  0.005  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  23.42 
 
 		 441 aa  43.9  0.005  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  22.87 
 
 		 456 aa  43.5  0.006  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
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