63 homologs were found in PanDaTox collection
for query gene Smon_1290 on replicon NC_013515
Organism: Streptobacillus moniliformis DSM 12112



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  100 
 
 		 406 aa  815    Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  48.54 
 
 		 427 aa  383  1e-105  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  42.55 
 
 		 423 aa  350  2e-95  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  42.61 
 
 		 444 aa  347  3e-94  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  43.07 
 
 		 456 aa  346  4e-94  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  41.65 
 
 		 441 aa  329  5.0000000000000004e-89  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  44.14 
 
 		 410 aa  322  6e-87  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  41.77 
 
 		 425 aa  321  1.9999999999999998e-86  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  40.19 
 
 		 440 aa  319  7e-86  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  39.61 
 
 		 420 aa  316  4e-85  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  45.16 
 
 		 420 aa  315  7e-85  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  43.35 
 
 		 419 aa  314  9.999999999999999e-85  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  45.18 
 
 		 428 aa  313  1.9999999999999998e-84  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  41.42 
 
 		 425 aa  313  2.9999999999999996e-84  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  41.42 
 
 		 425 aa  313  2.9999999999999996e-84  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  39.21 
 
 		 429 aa  306  4.0000000000000004e-82  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_006369  lpl2030  hypothetical protein  38.99 
 
 		 432 aa  298  9e-80  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  38.48 
 
 		 432 aa  298  2e-79  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  36.69 
 
 		 428 aa  288  9e-77  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  43.7 
 
 		 418 aa  288  1e-76  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  41.16 
 
 		 428 aa  286  5e-76  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  40.05 
 
 		 428 aa  286  7e-76  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_013440  Hoch_3406  hydroxymethylglutaryl-CoA reductase, degradative  38.89 
 
 		 443 aa  284  2.0000000000000002e-75  Haliangium ochraceum DSM 14365  Bacteria  normal  0.121756  normal  0.0808381 
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  42.44 
 
 		 436 aa  275  8e-73  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  41.1 
 
 		 436 aa  272  9e-72  Capnocytophaga ochracea DSM 7271  Bacteria  normal  1  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  41.32 
 
 		 437 aa  268  1e-70  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  39.61 
 
 		 401 aa  263  4.999999999999999e-69  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_013440  Hoch_5714  hydroxymethylglutaryl-CoA reductase, degradative  40.16 
 
 		 402 aa  259  5.0000000000000005e-68  Haliangium ochraceum DSM 14365  Bacteria  normal  0.148177  normal  1 
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  38.5 
 
 		 429 aa  252  1e-65  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_013721  HMPREF0424_0360  hydroxymethylglutaryl-CoA reductase, degradative  38.82 
 
 		 444 aa  231  2e-59  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  38.91 
 
 		 363 aa  221  9.999999999999999e-57  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  38.14 
 
 		 422 aa  186  7e-46  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  25.63 
 
 		 403 aa  68.2  0.0000000003  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.27 
 
 		 409 aa  63.2  0.000000008  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  26.39 
 
 		 1047 aa  63.2  0.000000008  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  28.73 
 
 		 408 aa  62.8  0.00000001  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  28.11 
 
 		 411 aa  62.8  0.00000001  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  28.46 
 
 		 408 aa  61.6  0.00000002  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  29 
 
 		 408 aa  61.6  0.00000002  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  26.88 
 
 		 418 aa  60.5  0.00000005  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  24.93 
 
 		 1125 aa  58.5  0.0000002  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  25.07 
 
 		 395 aa  58.5  0.0000002  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  22.16 
 
 		 403 aa  57.8  0.0000003  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  24.23 
 
 		 514 aa  56.2  0.000001  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  21.58 
 
 		 424 aa  53.5  0.000006  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  27.23 
 
 		 399 aa  52.4  0.00001  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.69 
 
 		 410 aa  50.4  0.00005  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  23.93 
 
 		 395 aa  50.8  0.00005  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  24.88 
 
 		 414 aa  49.3  0.0001  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  21.7 
 
 		 419 aa  47.8  0.0003  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.81 
 
 		 410 aa  47.8  0.0003  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  22.5 
 
 		 408 aa  47.8  0.0003  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  21.49 
 
 		 410 aa  47.4  0.0005  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  28.39 
 
 		 418 aa  47.4  0.0005  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  20.87 
 
 		 402 aa  47  0.0006  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  21.13 
 
 		 399 aa  46.6  0.0007  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.5 
 
 		 407 aa  45.8  0.001  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  21.39 
 
 		 420 aa  45.1  0.002  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.5 
 
 		 404 aa  45.1  0.002  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.39 
 
 		 398 aa  45.4  0.002  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  21.65 
 
 		 396 aa  45.4  0.002  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  21.83 
 
 		 426 aa  44.3  0.004  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.65 
 
 		 407 aa  43.1  0.008  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
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