48 homologs were found in PanDaTox collection
for query gene CBUD_0151 on replicon NC_009727
Organism: Coxiella burnetii Dugway 5J108-111



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  92.15 
 
 		 395 aa  726    Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
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NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  100 
 
 		 364 aa  758    Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  32.01 
 
 		 395 aa  204  2e-51  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  31.39 
 
 		 424 aa  191  2e-47  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  31.57 
 
 		 418 aa  187  3e-46  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
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NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  30.46 
 
 		 396 aa  180  2.9999999999999997e-44  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  30.67 
 
 		 395 aa  177  2e-43  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  31.15 
 
 		 420 aa  167  2e-40  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  33.04 
 
 		 420 aa  167  2.9999999999999998e-40  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  30.73 
 
 		 408 aa  165  1.0000000000000001e-39  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  29.77 
 
 		 411 aa  164  2.0000000000000002e-39  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  31.87 
 
 		 419 aa  164  2.0000000000000002e-39  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  31.01 
 
 		 408 aa  164  2.0000000000000002e-39  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  30.73 
 
 		 408 aa  164  3e-39  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  30.11 
 
 		 409 aa  164  3e-39  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  30.79 
 
 		 420 aa  161  1e-38  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  30.05 
 
 		 514 aa  160  2e-38  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  31.41 
 
 		 403 aa  159  5e-38  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  30.87 
 
 		 398 aa  155  1e-36  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  31.03 
 
 		 403 aa  151  1e-35  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  33.33 
 
 		 414 aa  150  4e-35  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  30.68 
 
 		 410 aa  149  8e-35  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  29.6 
 
 		 399 aa  145  1e-33  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  29.61 
 
 		 426 aa  143  6e-33  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  29.72 
 
 		 399 aa  142  7e-33  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  28.7 
 
 		 410 aa  142  9.999999999999999e-33  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  30.67 
 
 		 407 aa  141  9.999999999999999e-33  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  28.53 
 
 		 401 aa  140  4.999999999999999e-32  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  30.57 
 
 		 408 aa  139  1e-31  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  30.77 
 
 		 418 aa  137  2e-31  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  29.95 
 
 		 1283 aa  137  2e-31  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  28.94 
 
 		 410 aa  137  4e-31  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  31.44 
 
 		 404 aa  135  9e-31  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  32.37 
 
 		 407 aa  132  1.0000000000000001e-29  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  29.13 
 
 		 1047 aa  125  1e-27  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  30.39 
 
 		 402 aa  124  2e-27  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  29.63 
 
 		 1125 aa  122  9.999999999999999e-27  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  29.94 
 
 		 416 aa  110  4.0000000000000004e-23  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_009727  CBUD_0622  3-hydroxy-3-methylglutaryl-coenzyme A reductase  28.28 
 
 		 357 aa  107  4e-22  Coxiella burnetii Dugway 5J108-111  Bacteria  hitchhiker  0.000221084  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0723  hydroxymethylglutaryl-CoA reductase (NADPH)  28.28 
 
 		 355 aa  107  5e-22  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.000000000015079  n/a   
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  27.84 
 
 		 367 aa  103  5e-21  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  26.67 
 
 		 352 aa  94  4e-18  Thiomicrospira crunogena XCL-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  21.21 
 
 		 429 aa  52  0.00002  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  23.18 
 
 		 425 aa  50.1  0.00005  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  22.93 
 
 		 425 aa  50.1  0.00006  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  22.93 
 
 		 425 aa  50.1  0.00006  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  26.23 
 
 		 423 aa  44.7  0.002  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  21.84 
 
 		 410 aa  44.3  0.003  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
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