59 homologs were found in PanDaTox collection
for query gene STER_0620 on replicon NC_008532
Organism: Streptococcus thermophilus LMD-9



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  100 
 
 		 423 aa  873    Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  66.43 
 
 		 427 aa  558  1e-158  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  46.51 
 
 		 420 aa  368  1e-101  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  42.55 
 
 		 406 aa  350  2e-95  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  45.32 
 
 		 425 aa  347  3e-94  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  43.75 
 
 		 425 aa  344  1e-93  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  43.75 
 
 		 425 aa  344  1e-93  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.54 
 
 		 410 aa  338  9.999999999999999e-92  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  39.76 
 
 		 441 aa  309  5.9999999999999995e-83  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  40.62 
 
 		 444 aa  306  4.0000000000000004e-82  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  41.33 
 
 		 456 aa  306  5.0000000000000004e-82  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_013440  Hoch_3406  hydroxymethylglutaryl-CoA reductase, degradative  41.47 
 
 		 443 aa  296  5e-79  Haliangium ochraceum DSM 14365  Bacteria  normal  0.121756  normal  0.0808381 
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  40.43 
 
 		 428 aa  292  9e-78  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  44.09 
 
 		 401 aa  291  1e-77  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  40.48 
 
 		 440 aa  286  5.999999999999999e-76  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  39.71 
 
 		 429 aa  285  1.0000000000000001e-75  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_006369  lpl2030  hypothetical protein  40 
 
 		 432 aa  285  1.0000000000000001e-75  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  39.75 
 
 		 432 aa  284  2.0000000000000002e-75  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  40.57 
 
 		 420 aa  284  2.0000000000000002e-75  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  39.86 
 
 		 428 aa  283  4.0000000000000003e-75  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  39.86 
 
 		 428 aa  283  4.0000000000000003e-75  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  40.62 
 
 		 419 aa  274  2.0000000000000002e-72  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  40.14 
 
 		 428 aa  273  4.0000000000000004e-72  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  38.73 
 
 		 429 aa  261  2e-68  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  38.21 
 
 		 418 aa  248  1e-64  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_013440  Hoch_5714  hydroxymethylglutaryl-CoA reductase, degradative  38.85 
 
 		 402 aa  229  6e-59  Haliangium ochraceum DSM 14365  Bacteria  normal  0.148177  normal  1 
 
 
-
 
NC_013721  HMPREF0424_0360  hydroxymethylglutaryl-CoA reductase, degradative  36.88 
 
 		 444 aa  226  4e-58  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  35.37 
 
 		 436 aa  226  9e-58  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  38.16 
 
 		 363 aa  224  2e-57  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  36.86 
 
 		 436 aa  219  1e-55  Capnocytophaga ochracea DSM 7271  Bacteria  normal  1  n/a   
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  34.32 
 
 		 437 aa  208  1e-52  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  32.35 
 
 		 422 aa  188  2e-46  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  25.6 
 
 		 399 aa  62.8  0.00000001  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  31.91 
 
 		 1125 aa  60.5  0.00000005  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.56 
 
 		 395 aa  60.5  0.00000006  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  25.27 
 
 		 409 aa  58.2  0.0000003  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  29.79 
 
 		 1047 aa  57.4  0.0000004  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  25.12 
 
 		 1283 aa  57.4  0.0000005  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  25.35 
 
 		 403 aa  57  0.0000007  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  27.78 
 
 		 403 aa  56.6  0.0000008  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  27.49 
 
 		 402 aa  53.9  0.000006  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  27.17 
 
 		 410 aa  52.8  0.00001  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  27.74 
 
 		 398 aa  53.1  0.00001  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  28.09 
 
 		 367 aa  50.8  0.00005  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  26.4 
 
 		 514 aa  50.1  0.00008  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.88 
 
 		 410 aa  50.1  0.00008  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.21 
 
 		 399 aa  49.3  0.0001  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  26.32 
 
 		 407 aa  48.9  0.0002  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  0.439309 
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  22.66 
 
 		 352 aa  46.6  0.0009  Thiomicrospira crunogena XCL-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  21.84 
 
 		 426 aa  45.1  0.002  Candidatus Methanoregula boonei 6A8  Archaea  normal  1  normal  1 
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  25.54 
 
 		 410 aa  45.4  0.002  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  26.23 
 
 		 364 aa  45.1  0.003  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  22.77 
 
 		 395 aa  44.3  0.004  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.02 
 
 		 418 aa  44.7  0.004  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  23.29 
 
 		 418 aa  43.9  0.005  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  25.54 
 
 		 408 aa  43.9  0.005  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.79 
 
 		 411 aa  43.9  0.005  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.73 
 
 		 414 aa  43.1  0.009  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  25 
 
 		 404 aa  43.1  0.01  Methanocorpusculum labreanum Z  Archaea  normal  1  hitchhiker  0.0000342006 
 
 
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