46 homologs were found in PanDaTox collection
for query gene Lreu_0206 on replicon NC_009513
Organism: Lactobacillus reuteri DSM 20016



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  100 
 
 		 420 aa  862    Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  46.51 
 
 		 423 aa  368  1e-101  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.27 
 
 		 410 aa  343  2.9999999999999997e-93  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  45.32 
 
 		 427 aa  341  1e-92  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  41.98 
 
 		 425 aa  318  1e-85  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
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NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  41.98 
 
 		 425 aa  318  1e-85  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  41.98 
 
 		 425 aa  318  2e-85  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  44.23 
 
 		 401 aa  317  2e-85  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  39.61 
 
 		 406 aa  316  4e-85  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  42.79 
 
 		 441 aa  308  1.0000000000000001e-82  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  41.81 
 
 		 419 aa  297  2e-79  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  41.29 
 
 		 444 aa  296  6e-79  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  41.47 
 
 		 456 aa  296  7e-79  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  41.97 
 
 		 420 aa  293  4e-78  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  41.78 
 
 		 440 aa  292  8e-78  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  43.17 
 
 		 429 aa  292  8e-78  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  42.09 
 
 		 428 aa  291  1e-77  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  40.82 
 
 		 428 aa  284  2.0000000000000002e-75  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  40.82 
 
 		 428 aa  284  2.0000000000000002e-75  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  42.86 
 
 		 428 aa  276  5e-73  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_013440  Hoch_3406  hydroxymethylglutaryl-CoA reductase, degradative  42.46 
 
 		 443 aa  276  7e-73  Haliangium ochraceum DSM 14365  Bacteria  normal  0.121756  normal  0.0808381 
 
 
-
 
NC_006369  lpl2030  hypothetical protein  37.12 
 
 		 432 aa  260  3e-68  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  36.88 
 
 		 432 aa  259  7e-68  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  36.8 
 
 		 429 aa  257  3e-67  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_013721  HMPREF0424_0360  hydroxymethylglutaryl-CoA reductase, degradative  38.2 
 
 		 444 aa  246  4.9999999999999997e-64  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  35.12 
 
 		 436 aa  244  9.999999999999999e-64  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  40.48 
 
 		 363 aa  244  3e-63  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  42.06 
 
 		 418 aa  236  5.0000000000000005e-61  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  34.49 
 
 		 437 aa  236  7e-61  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  35.57 
 
 		 436 aa  224  2e-57  Capnocytophaga ochracea DSM 7271  Bacteria  normal  1  n/a   
 
 
-
 
NC_013440  Hoch_5714  hydroxymethylglutaryl-CoA reductase, degradative  39.68 
 
 		 402 aa  209  6e-53  Haliangium ochraceum DSM 14365  Bacteria  normal  0.148177  normal  1 
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  30.12 
 
 		 422 aa  204  3e-51  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  22.97 
 
 		 403 aa  57  0.0000006  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  23.76 
 
 		 418 aa  54.3  0.000004  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  23.38 
 
 		 399 aa  50.1  0.00007  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  28.39 
 
 		 1125 aa  50.1  0.00008  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  21.57 
 
 		 399 aa  49.7  0.00009  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  21.53 
 
 		 424 aa  49.7  0.00009  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.06 
 
 		 409 aa  49.3  0.0001  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  25.96 
 
 		 402 aa  48.1  0.0003  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.73 
 
 		 408 aa  46.6  0.0009  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  22.47 
 
 		 403 aa  45.8  0.001  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  21.88 
 
 		 408 aa  45.8  0.001  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.32 
 
 		 408 aa  45.4  0.002  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  24 
 
 		 398 aa  44.7  0.003  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  22.22 
 
 		 418 aa  43.1  0.01  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
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