58 homologs were found in PanDaTox collection
for query gene SaurJH9_2568 on replicon NC_009487
Organism: Staphylococcus aureus subsp. aureus JH9



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_002976  SERP2121  hydroxymethylglutaryl-CoA reductase, degradative  81.37 
 
 		 425 aa  709    Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_2568  hydroxymethylglutaryl-CoA reductase, degradative  100 
 
 		 425 aa  864    Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2621  hydroxymethylglutaryl-CoA reductase, degradative  100 
 
 		 425 aa  864    Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008527  LACR_1664  3-hydroxy-3-methylglutaryl-coenzyme A reductase  47.03 
 
 		 410 aa  379  1e-104  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.0024632  n/a   
 
 
-
 
NC_008532  STER_0620  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.75 
 
 		 423 aa  344  1e-93  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_004116  SAG1317  3-hydroxy-3-methylglutaryl-CoA reductase  42.93 
 
 		 427 aa  326  6e-88  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_009513  Lreu_0206  3-hydroxy-3-methylglutaryl-coenzyme A reductase  41.98 
 
 		 420 aa  318  1e-85  Lactobacillus reuteri DSM 20016  Bacteria  normal  1  n/a   
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  41.42 
 
 		 406 aa  313  2.9999999999999996e-84  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  40.52 
 
 		 444 aa  298  1e-79  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  40.28 
 
 		 429 aa  296  5e-79  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  39.57 
 
 		 456 aa  294  2e-78  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  0.316381 
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  41.13 
 
 		 428 aa  290  2e-77  Pseudomonas putida F1  Bacteria  normal  0.272086  normal  1 
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  40.85 
 
 		 428 aa  287  2e-76  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  39.9 
 
 		 428 aa  287  2e-76  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.316182 
 
 
-
 
NC_008553  Mthe_0936  hydroxymethylglutaryl-CoA reductase, degradative  38.97 
 
 		 419 aa  281  1e-74  Methanosaeta thermophila PT  Archaea  normal  1  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  41.71 
 
 		 440 aa  279  6e-74  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00353445 
 
 
-
 
NC_008531  LEUM_0335  hydroxymethylglutaryl-CoA reductase  39.76 
 
 		 401 aa  278  2e-73  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  1  n/a   
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  40 
 
 		 420 aa  275  1.0000000000000001e-72  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_008698  Tpen_0927  hydroxymethylglutaryl-CoA reductase, degradative  39.61 
 
 		 428 aa  274  2.0000000000000002e-72  Thermofilum pendens Hrk 5  Archaea  normal  1  n/a   
 
 
-
 
NC_009972  Haur_3539  hydroxymethylglutaryl-CoA reductase, degradative  39.19 
 
 		 441 aa  273  4.0000000000000004e-72  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0777406  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  39.61 
 
 		 429 aa  266  7e-70  Lactobacillus gasseri ATCC 33323  Bacteria  normal  1  hitchhiker  0.0000000000375721 
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.49 
 
 		 363 aa  260  3e-68  Oenococcus oeni PSU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_006369  lpl2030  hypothetical protein  36.34 
 
 		 432 aa  251  2e-65  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_013440  Hoch_3406  hydroxymethylglutaryl-CoA reductase, degradative  40.05 
 
 		 443 aa  250  3e-65  Haliangium ochraceum DSM 14365  Bacteria  normal  0.121756  normal  0.0808381 
 
 
-
 
NC_006368  lpp2035  hypothetical protein  35.88 
 
 		 432 aa  248  2e-64  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_013721  HMPREF0424_0360  hydroxymethylglutaryl-CoA reductase, degradative  37.1 
 
 		 444 aa  239  5e-62  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_010085  Nmar_1560  hydroxymethylglutaryl-CoA reductase, degradative  38.04 
 
 		 418 aa  239  5e-62  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  1 
 
 
-
 
NC_009441  Fjoh_1418  hydroxymethylglutaryl-CoA reductase, degradative  35.27 
 
 		 437 aa  230  5e-59  Flavobacterium johnsoniae UW101  Bacteria  normal  0.984667  n/a   
 
 
-
 
NC_014230  CA2559_04185  3-hydroxy-3-methylglutaryl-coenzyme A reductase  35.89 
 
 		 436 aa  229  8e-59  Croceibacter atlanticus HTCC2559  Bacteria  normal  1  n/a   
 
 
-
 
NC_013162  Coch_1037  hydroxymethylglutaryl-CoA reductase, degradative  34.08 
 
 		 436 aa  227  4e-58  Capnocytophaga ochracea DSM 7271  Bacteria  normal  1  n/a   
 
 
-
 
NC_011728  BbuZS7_0705  hydroxymethylglutaryl-CoA reductase, degradative  34.83 
 
 		 422 aa  222  9.999999999999999e-57  Borrelia burgdorferi ZS7  Bacteria  normal  1  n/a   
 
 
-
 
NC_013440  Hoch_5714  hydroxymethylglutaryl-CoA reductase, degradative  40.42 
 
 		 402 aa  214  2.9999999999999995e-54  Haliangium ochraceum DSM 14365  Bacteria  normal  0.148177  normal  1 
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  26.34 
 
 		 1047 aa  79.3  0.0000000000001  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  1  normal  1 
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  25.54 
 
 		 1125 aa  67.4  0.0000000004  Aspergillus nidulans FGSC A4  Eukaryota  normal  1  normal  1 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.4 
 
 		 409 aa  67  0.0000000006  Sulfolobus solfataricus 98/2  Archaea  normal  1  n/a   
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.03 
 
 		 410 aa  61.6  0.00000003  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal  1 
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.73 
 
 		 403 aa  58.9  0.0000002  Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  22.6 
 
 		 1283 aa  58.2  0.0000003  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  1  n/a   
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  24.59 
 
 		 410 aa  57.4  0.0000004  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  22.96 
 
 		 395 aa  57  0.0000007  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  25.39 
 
 		 395 aa  57  0.0000007  Thermoproteus neutrophilus V24Sta  Archaea  normal  1  normal  1 
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.86 
 
 		 414 aa  55.1  0.000002  Methanococcoides burtonii DSM 6242  Archaea  normal  1  n/a   
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  24.79 
 
 		 514 aa  54.3  0.000004  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  23.08 
 
 		 424 aa  52  0.00002  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.46 
 
 		 418 aa  50.4  0.00005  Methanococcus aeolicus Nankai-3  Archaea  normal  1  n/a   
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  22.93 
 
 		 364 aa  50.1  0.00008  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  1  n/a   
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  26.01 
 
 		 399 aa  49.7  0.00009  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.19 
 
 		 408 aa  49.3  0.0001  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.78 
 
 		 408 aa  49.3  0.0001  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  24.7 
 
 		 399 aa  48.1  0.0003  Pyrobaculum islandicum DSM 4184  Archaea  normal  1  hitchhiker  0.00207544 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  23.64 
 
 		 403 aa  48.1  0.0003  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal  1 
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  21.64 
 
 		 410 aa  47.8  0.0004  Caldivirga maquilingensis IC-167  Archaea  normal  1  normal  1 
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  25.82 
 
 		 398 aa  47.4  0.0005  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  22.98 
 
 		 411 aa  47  0.0006  Methanococcus vannielii SB  Archaea  normal  1  n/a   
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  23.38 
 
 		 418 aa  47  0.0007  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  21.7 
 
 		 408 aa  46.6  0.0009  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  21.6 
 
 		 408 aa  45.1  0.002  Methanococcus maripaludis C7  Archaea  normal  1  normal  1 
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  22.16 
 
 		 395 aa  43.1  0.009  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
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