More than 300 homologs were found in PanDaTox collection
for query gene Slin_3454 on replicon NC_013730
Organism: Spirosoma linguale DSM 74



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013730  Slin_3454  two component transcriptional regulator, winged helix family  100 
 
 
223 aa  447  1e-125  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  49.78 
 
 
227 aa  197  2.0000000000000003e-49  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  46.4 
 
 
228 aa  196  3e-49  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  49.77 
 
 
227 aa  195  4.0000000000000005e-49  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  44.8 
 
 
223 aa  195  5.000000000000001e-49  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  49.77 
 
 
227 aa  195  5.000000000000001e-49  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  48.87 
 
 
225 aa  195  5.000000000000001e-49  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  47.32 
 
 
225 aa  194  6e-49  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  47.49 
 
 
225 aa  194  7e-49  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  45.95 
 
 
226 aa  194  7e-49  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  45.95 
 
 
223 aa  194  8.000000000000001e-49  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  46.58 
 
 
225 aa  194  8.000000000000001e-49  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  46.58 
 
 
225 aa  194  8.000000000000001e-49  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  46.58 
 
 
225 aa  194  8.000000000000001e-49  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  47.53 
 
 
227 aa  193  1e-48  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  47.03 
 
 
225 aa  192  3e-48  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  45.29 
 
 
230 aa  191  7e-48  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  46.79 
 
 
223 aa  191  9e-48  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  44.34 
 
 
224 aa  191  1e-47  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_009511  Swit_4798  two component transcriptional regulator  47.98 
 
 
230 aa  191  1e-47  Sphingomonas wittichii RW1  Bacteria  normal  normal  0.358461 
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  46.4 
 
 
224 aa  190  1e-47  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  44.64 
 
 
222 aa  189  2.9999999999999997e-47  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  43.89 
 
 
223 aa  189  2.9999999999999997e-47  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  45.05 
 
 
223 aa  188  4e-47  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009667  Oant_2666  two component transcriptional regulator  45.74 
 
 
255 aa  189  4e-47  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.128945  n/a   
 
 
-
 
NC_004310  BR0612  DNA-binding response regulator  45.74 
 
 
235 aa  188  5.999999999999999e-47  Brucella suis 1330  Bacteria  normal  0.688885  n/a   
 
 
-
 
NC_009505  BOV_0611  DNA-binding response regulator  45.74 
 
 
235 aa  188  5.999999999999999e-47  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  46.85 
 
 
226 aa  188  5.999999999999999e-47  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  46.4 
 
 
226 aa  187  9e-47  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  44.39 
 
 
224 aa  186  2e-46  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  42.73 
 
 
224 aa  186  2e-46  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  44.59 
 
 
226 aa  186  3e-46  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  44.8 
 
 
240 aa  186  3e-46  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  46.4 
 
 
226 aa  186  3e-46  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  45.54 
 
 
242 aa  185  4e-46  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  42.99 
 
 
225 aa  185  4e-46  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  43.44 
 
 
224 aa  185  5e-46  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_008740  Maqu_3740  two component transcriptional regulator  46.22 
 
 
226 aa  185  5e-46  Marinobacter aquaeolei VT8  Bacteria  normal  0.487084  n/a   
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  45.95 
 
 
228 aa  185  6e-46  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  47.06 
 
 
227 aa  184  6e-46  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  44.34 
 
 
224 aa  184  7e-46  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_007643  Rru_A2913  two component transcriptional regulator  46.46 
 
 
227 aa  184  1.0000000000000001e-45  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.0379396  n/a   
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  46.15 
 
 
225 aa  184  1.0000000000000001e-45  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  41.7 
 
 
224 aa  184  1.0000000000000001e-45  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  42.73 
 
 
230 aa  184  1.0000000000000001e-45  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_014148  Plim_2757  response regulator receiver  42.67 
 
 
225 aa  183  1.0000000000000001e-45  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  45.58 
 
 
228 aa  183  2.0000000000000003e-45  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  45.54 
 
 
228 aa  183  2.0000000000000003e-45  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  44.59 
 
 
226 aa  182  2.0000000000000003e-45  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  45.7 
 
 
225 aa  183  2.0000000000000003e-45  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  43.18 
 
 
225 aa  183  2.0000000000000003e-45  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_008254  Meso_0902  two component transcriptional regulator  44.39 
 
 
224 aa  182  2.0000000000000003e-45  Chelativorans sp. BNC1  Bacteria  normal  0.375579  n/a   
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  45.54 
 
 
228 aa  183  2.0000000000000003e-45  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010803  Clim_1291  two component transcriptional regulator, winged helix family  43.05 
 
 
222 aa  182  3e-45  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  45.25 
 
 
227 aa  182  3e-45  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  45.05 
 
 
228 aa  182  3e-45  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  42.34 
 
 
283 aa  182  3e-45  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  43.89 
 
 
224 aa  182  3e-45  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  44.59 
 
 
226 aa  182  4.0000000000000006e-45  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  44.8 
 
 
231 aa  182  4.0000000000000006e-45  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_010468  EcolC_3412  two component heavy metal response transcriptional regulator  43.18 
 
 
226 aa  182  4.0000000000000006e-45  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_010831  Cphamn1_0990  two component transcriptional regulator, winged helix family  43.44 
 
 
222 aa  182  5.0000000000000004e-45  Chlorobium phaeobacteroides BS1  Bacteria  hitchhiker  0.000957791  decreased coverage  0.0000715536 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  44.59 
 
 
226 aa  182  5.0000000000000004e-45  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  42.66 
 
 
225 aa  182  5.0000000000000004e-45  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  45.25 
 
 
225 aa  181  8.000000000000001e-45  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  45.5 
 
 
226 aa  180  1e-44  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  46.15 
 
 
230 aa  180  1e-44  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  42.53 
 
 
223 aa  181  1e-44  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  46.58 
 
 
219 aa  180  2e-44  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_2762  two component transcriptional regulator, winged helix family  43.5 
 
 
225 aa  180  2e-44  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_006368  lpp0781  hypothetical protein  40.27 
 
 
223 aa  179  2e-44  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_006369  lpl0752  hypothetical protein  41.18 
 
 
223 aa  179  2e-44  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_013525  Tter_1435  two component transcriptional regulator, winged helix family  44.59 
 
 
233 aa  180  2e-44  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_007511  Bcep18194_B2430  two component heavy metal response transcriptional regulator  45.25 
 
 
227 aa  179  2e-44  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_0528  two component heavy metal response transcriptional regulator  45.87 
 
 
223 aa  180  2e-44  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  42.53 
 
 
224 aa  180  2e-44  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_007650  BTH_II0376  DNA-binding response regulator IrlR  44.34 
 
 
230 aa  180  2e-44  Burkholderia thailandensis E264  Bacteria  normal  0.083776  n/a   
 
 
-
 
NC_009720  Xaut_3517  two component transcriptional regulator  43.05 
 
 
238 aa  180  2e-44  Xanthobacter autotrophicus Py2  Bacteria  normal  0.0423488  normal  0.321822 
 
 
-
 
NC_013730  Slin_4793  two component transcriptional regulator, winged helix family  44.39 
 
 
225 aa  179  2.9999999999999997e-44  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  43.89 
 
 
224 aa  179  2.9999999999999997e-44  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_010515  Bcenmc03_3842  two component heavy metal response transcriptional regulator  45.25 
 
 
227 aa  179  2.9999999999999997e-44  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.67414 
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  42.53 
 
 
224 aa  179  2.9999999999999997e-44  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_013730  Slin_1849  two component transcriptional regulator, winged helix family  42.86 
 
 
228 aa  179  2.9999999999999997e-44  Spirosoma linguale DSM 74  Bacteria  normal  0.418833  normal 
 
 
-
 
NC_008061  Bcen_4683  two component heavy metal response transcriptional regulator  44.8 
 
 
228 aa  179  2.9999999999999997e-44  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.222547  n/a   
 
 
-
 
NC_008543  Bcen2424_3680  two component heavy metal response transcriptional regulator  44.8 
 
 
228 aa  179  2.9999999999999997e-44  Burkholderia cenocepacia HI2424  Bacteria  normal  0.224842  normal 
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  43.44 
 
 
224 aa  179  4e-44  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  43.69 
 
 
226 aa  179  4e-44  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  42.53 
 
 
224 aa  179  4e-44  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_011060  Ppha_0994  two component transcriptional regulator, winged helix family  43.12 
 
 
227 aa  178  4.999999999999999e-44  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  0.337893  n/a   
 
 
-
 
NC_013730  Slin_2552  two component transcriptional regulator, winged helix family  43.81 
 
 
230 aa  178  4.999999999999999e-44  Spirosoma linguale DSM 74  Bacteria  hitchhiker  0.0000276879  normal  0.180215 
 
 
-
 
NC_008554  Sfum_2007  two component transcriptional regulator  45.95 
 
 
223 aa  178  4.999999999999999e-44  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  46.61 
 
 
225 aa  178  7e-44  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_009079  BMA10247_A1180  transcriptional activator IrlR  43.89 
 
 
229 aa  178  7e-44  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0831411  n/a   
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  42.08 
 
 
224 aa  178  7e-44  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_0402  transcriptional activator IrlR  43.89 
 
 
229 aa  178  7e-44  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0800763  n/a   
 
 
-
 
NC_006349  BMAA1028  DNA-binding response regulator IrlR  43.89 
 
 
229 aa  178  7e-44  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0282692  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0030  DNA-binding response regulator IrlR  43.89 
 
 
229 aa  178  7e-44  Burkholderia pseudomallei 1710b  Bacteria  normal  0.122488  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1439  transcriptional activator IrlR  43.89 
 
 
229 aa  178  7e-44  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_009075  BURPS668_A1524  transcriptional activator protein IrlR  43.89 
 
 
229 aa  178  7e-44  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_008784  BMASAVP1_0010  transcriptional activator IrlR  43.89 
 
 
229 aa  178  7e-44  Burkholderia mallei SAVP1  Bacteria  normal  0.121051  n/a   
 
 
-
 
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