More than 300 homologs were found in PanDaTox collection
for query gene Lcho_1537 on replicon NC_010524
Organism: Leptothrix cholodnii SP-6



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010524  Lcho_1537  methyl-accepting chemotaxis sensory transducer  100 
 
 
377 aa  748    Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0414655 
 
 
-
 
NC_009439  Pmen_1571  methyl-accepting chemotaxis sensory transducer  32.7 
 
 
362 aa  134  3e-30  Pseudomonas mendocina ymp  Bacteria  normal  normal 
 
 
-
 
NC_004578  PSPTO_0916  methyl-accepting chemotaxis protein, putative  32.36 
 
 
404 aa  121  1.9999999999999998e-26  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_007954  Sden_3293  chemotaxis sensory transducer  29.69 
 
 
387 aa  121  1.9999999999999998e-26  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_0789  chemotaxis sensory transducer  29.85 
 
 
405 aa  119  7.999999999999999e-26  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_007908  Rfer_0898  methyl-accepting chemotaxis sensory transducer  30.79 
 
 
379 aa  116  6e-25  Rhodoferax ferrireducens T118  Bacteria  normal  0.827974  n/a   
 
 
-
 
NC_010524  Lcho_3795  methyl-accepting chemotaxis sensory transducer  26.75 
 
 
383 aa  107  3e-22  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_011662  Tmz1t_1314  methyl-accepting chemotaxis sensory transducer  30 
 
 
426 aa  104  2e-21  Thauera sp. MZ1T  Bacteria  normal  0.116934  n/a   
 
 
-
 
NC_009457  VC0395_A1006  methyl-accepting chemotaxis protein  30.8 
 
 
411 aa  79.7  0.00000000000008  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0350  methyl-accepting chemotaxis sensory transducer  32.97 
 
 
430 aa  78.6  0.0000000000002  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_008789  Hhal_2159  methyl-accepting chemotaxis sensory transducer  24.78 
 
 
414 aa  77.8  0.0000000000003  Halorhodospira halophila SL1  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_0470  methyl-accepting chemotaxis protein, putative  37.4 
 
 
430 aa  76.6  0.0000000000006  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS0356  methyl-accepting chemotaxis protein  37.4 
 
 
430 aa  76.6  0.0000000000006  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_0339  methyl-accepting chemotaxis protein  37.4 
 
 
430 aa  76.6  0.0000000000006  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK0342  methyl-accepting chemotaxis protein  37.4 
 
 
430 aa  76.6  0.0000000000006  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_0370  methyl-accepting chemotaxis protein  37.4 
 
 
430 aa  76.6  0.0000000000006  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0189041  n/a   
 
 
-
 
NC_009654  Mmwyl1_3295  methyl-accepting chemotaxis sensory transducer  36.79 
 
 
384 aa  75.5  0.000000000001  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_009674  Bcer98_0346  methyl-accepting chemotaxis sensory transducer  40.17 
 
 
430 aa  75.9  0.000000000001  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013158  Huta_2382  methyl-accepting chemotaxis sensory transducer  41.76 
 
 
871 aa  75.5  0.000000000001  Halorhabdus utahensis DSM 12940  Archaea  normal  0.115192  n/a   
 
 
-
 
NC_009621  Smed_5117  methyl-accepting chemotaxis sensory transducer  46.24 
 
 
545 aa  75.1  0.000000000002  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.0275586 
 
 
-
 
NC_010718  Nther_2653  methyl-accepting chemotaxis sensory transducer  31.13 
 
 
583 aa  75.1  0.000000000002  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_011658  BCAH187_A0469  methyl-accepting chemotaxis protein  36.59 
 
 
430 aa  75.1  0.000000000002  Bacillus cereus AH187  Bacteria  normal  0.51819  n/a   
 
 
-
 
NC_014150  Bmur_2635  methyl-accepting chemotaxis sensory transducer  29.71 
 
 
608 aa  74.7  0.000000000003  Brachyspira murdochii DSM 12563  Bacteria  unclonable  9.45826e-19  n/a   
 
 
-
 
NC_011773  BCAH820_0405  methyl-accepting chemotaxis protein  36.59 
 
 
430 aa  74.3  0.000000000003  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011138  MADE_03238  chemotaxis sensory transducer  29.76 
 
 
429 aa  74.7  0.000000000003  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_013522  Taci_1680  methyl-accepting chemotaxis sensory transducer  47.95 
 
 
279 aa  73.9  0.000000000004  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A0418  methyl-accepting chemotaxis protein  46.24 
 
 
430 aa  73.9  0.000000000004  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B4900  methyl-accepting chemotaxis protein  46.24 
 
 
430 aa  74.3  0.000000000004  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_0410  methyl-accepting chemotaxis sensory transducer  27.53 
 
 
548 aa  73.6  0.000000000005  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_2453  methyl-accepting chemotaxis sensory transducer  34.51 
 
 
572 aa  73.6  0.000000000005  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_0643  putative methyl-accepting chemotaxis sensory transducer  32.77 
 
 
478 aa  73.6  0.000000000005  Shewanella amazonensis SB2B  Bacteria  hitchhiker  0.000131612  normal 
 
 
-
 
NC_013522  Taci_0309  methyl-accepting chemotaxis sensory transducer with Cache sensor  31.5 
 
 
677 aa  73.6  0.000000000006  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  unclonable  0.000000502143  n/a   
 
 
-
 
NC_009654  Mmwyl1_1836  methyl-accepting chemotaxis sensory transducer  34.62 
 
 
359 aa  73.2  0.000000000007  Marinomonas sp. MWYL1  Bacteria  normal  0.126283  normal  0.522282 
 
 
-
 
NC_011138  MADE_00410  methyl-accepting chemotaxis protein  26.27 
 
 
394 aa  73.2  0.000000000007  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007796  Mhun_0331  methyl-accepting chemotaxis sensory transducer  33.56 
 
 
701 aa  73.2  0.000000000007  Methanospirillum hungatei JF-1  Archaea  normal  0.0634228  normal 
 
 
-
 
NC_005945  BAS5276  methyl-accepting chemotaxis protein  26.67 
 
 
433 aa  72.8  0.000000000009  Bacillus anthracis str. Sterne  Bacteria  normal  0.085995  n/a   
 
 
-
 
NC_011138  MADE_03248  chemotaxis sensory transducer  36.73 
 
 
635 aa  72.8  0.000000000009  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_1140  chemotaxis sensory transducer  31.65 
 
 
418 aa  72.8  0.000000000009  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007530  GBAA_5673  methyl-accepting chemotaxis protein  26.67 
 
 
433 aa  72.8  0.000000000009  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_2860  methyl-accepting chemotaxis sensory transducer  26.75 
 
 
555 aa  72.8  0.000000000009  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  hitchhiker  0.000127985 
 
 
-
 
NC_003909  BCE_5552  methyl-accepting chemotaxis protein  26.67 
 
 
433 aa  72.4  0.00000000001  Bacillus cereus ATCC 10987  Bacteria  decreased coverage  0.000000569717  n/a   
 
 
-
 
NC_007005  Psyr_2241  histidine kinase, HAMP region: chemotaxis sensory transducer  35.81 
 
 
598 aa  72.4  0.00000000001  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.130389  normal  0.394001 
 
 
-
 
NC_013202  Hmuk_2424  methyl-accepting chemotaxis sensory transducer  39.82 
 
 
809 aa  72.4  0.00000000001  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal  0.052407 
 
 
-
 
NC_009674  Bcer98_0489  methyl-accepting chemotaxis sensory transducer  30.57 
 
 
660 aa  72.4  0.00000000001  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_5519  methyl-accepting chemotaxis protein  26.67 
 
 
433 aa  72.8  0.00000000001  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011898  Ccel_0219  methyl-accepting chemotaxis sensory transducer  30.57 
 
 
484 aa  72.4  0.00000000001  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_03417  methyl-accepting chemotaxis protein  41.26 
 
 
674 aa  71.6  0.00000000002  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.617562  n/a   
 
 
-
 
NC_007796  Mhun_2032  methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor  27.37 
 
 
1285 aa  72  0.00000000002  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.295891 
 
 
-
 
NC_009674  Bcer98_3605  methyl-accepting chemotaxis sensory transducer  37.82 
 
 
666 aa  71.6  0.00000000002  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_003910  CPS_1621  methyl-accepting chemotaxis protein  29.57 
 
 
513 aa  70.9  0.00000000003  Colwellia psychrerythraea 34H  Bacteria  normal  0.113175  n/a   
 
 
-
 
NC_004578  PSPTO_2475  methyl-accepting chemotaxis protein  37.67 
 
 
598 aa  70.9  0.00000000003  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.0390427  n/a   
 
 
-
 
NC_011830  Dhaf_2082  methyl-accepting chemotaxis sensory transducer  40 
 
 
568 aa  70.9  0.00000000003  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00000211004  n/a   
 
 
-
 
NC_013161  Cyan8802_0788  methyl-accepting chemotaxis sensory transducer  34.56 
 
 
484 aa  70.9  0.00000000003  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_013457  VEA_000202  methyl-accepting chemotaxis protein  34.29 
 
 
476 aa  71.2  0.00000000003  Vibrio sp. Ex25  Bacteria  normal  0.856149  n/a   
 
 
-
 
NC_007644  Moth_0502  methyl-accepting chemotaxis sensory transducer  31.79 
 
 
508 aa  71.2  0.00000000003  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.0174896  normal 
 
 
-
 
NC_009486  Tpet_0550  methyl-accepting chemotaxis sensory transducer  36.79 
 
 
660 aa  70.9  0.00000000003  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.00000171017  n/a   
 
 
-
 
NC_007954  Sden_2435  chemotaxis sensory transducer  37.16 
 
 
391 aa  71.2  0.00000000003  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_0457  methyl-accepting chemotaxis sensory transducer  34.53 
 
 
356 aa  71.2  0.00000000003  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_010483  TRQ2_0564  methyl-accepting chemotaxis sensory transducer with Cache sensor  36.79 
 
 
660 aa  70.9  0.00000000003  Thermotoga sp. RQ2  Bacteria  decreased coverage  0.0020921  n/a   
 
 
-
 
NC_011830  Dhaf_0529  methyl-accepting chemotaxis sensory transducer  40.29 
 
 
573 aa  70.9  0.00000000004  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0116952  n/a   
 
 
-
 
NC_013440  Hoch_3254  methyl-accepting chemotaxis sensory transducer  42.7 
 
 
612 aa  70.9  0.00000000004  Haliangium ochraceum DSM 14365  Bacteria  normal  0.0159313  normal  0.0166963 
 
 
-
 
NC_011726  PCC8801_0762  methyl-accepting chemotaxis sensory transducer  34.56 
 
 
484 aa  70.9  0.00000000004  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_014150  Bmur_1805  methyl-accepting chemotaxis sensory transducer with Cache sensor  35.04 
 
 
655 aa  70.5  0.00000000004  Brachyspira murdochii DSM 12563  Bacteria  hitchhiker  0.00000396464  n/a   
 
 
-
 
NC_009438  Sputcn32_1827  methyl-accepting chemotaxis sensory transducer  35.86 
 
 
502 aa  70.5  0.00000000004  Shewanella putrefaciens CN-32  Bacteria  hitchhiker  0.00626539  n/a   
 
 
-
 
NC_007796  Mhun_0951  methyl-accepting chemotaxis sensory transducer  31.68 
 
 
1332 aa  70.9  0.00000000004  Methanospirillum hungatei JF-1  Archaea  normal  0.514754  normal  0.661078 
 
 
-
 
NC_011772  BCG9842_B0088  methyl-accepting chemotaxis protein  37.4 
 
 
666 aa  70.5  0.00000000004  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_008043  TM1040_3242  methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor  32.93 
 
 
880 aa  70.5  0.00000000004  Ruegeria sp. TM1040  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A5156  methyl-accepting chemotaxis protein  37.4 
 
 
666 aa  70.5  0.00000000005  Bacillus cereus B4264  Bacteria  normal  0.99909  n/a   
 
 
-
 
NC_014150  Bmur_1256  methyl-accepting chemotaxis sensory transducer with Cache sensor  49.3 
 
 
612 aa  70.5  0.00000000005  Brachyspira murdochii DSM 12563  Bacteria  normal  n/a   
 
 
-
 
NC_014150  Bmur_1633  methyl-accepting chemotaxis sensory transducer  41.46 
 
 
612 aa  70.1  0.00000000006  Brachyspira murdochii DSM 12563  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_1066  methyl-accepting chemotaxis sensory transducer  39.45 
 
 
705 aa  70.1  0.00000000006  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_010003  Pmob_0696  methyl-accepting chemotaxis sensory transducer with Cache sensor  25.2 
 
 
659 aa  70.1  0.00000000006  Petrotoga mobilis SJ95  Bacteria  normal  0.738999  n/a   
 
 
-
 
NC_013512  Sdel_1316  chemotaxis sensory transducer  41.77 
 
 
704 aa  70.1  0.00000000006  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  0.0285504  n/a   
 
 
-
 
NC_011312  VSAL_I2130  methyl-accepting chemotaxis protein  37.12 
 
 
546 aa  70.1  0.00000000006  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.665531  n/a   
 
 
-
 
NC_009012  Cthe_1266  methyl-accepting chemotaxis sensory transducer  29.01 
 
 
822 aa  70.1  0.00000000006  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_2874  methyl-accepting chemotaxis sensory transducer  33.09 
 
 
771 aa  69.7  0.00000000007  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_0599  methyl-accepting chemotaxis sensory transducer  45.16 
 
 
539 aa  70.1  0.00000000007  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_008340  Mlg_1152  methyl-accepting chemotaxis sensory transducer  47.13 
 
 
484 aa  69.7  0.00000000007  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.26629  normal 
 
 
-
 
NC_013216  Dtox_3798  methyl-accepting chemotaxis sensory transducer  43.33 
 
 
397 aa  70.1  0.00000000007  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_008346  Swol_2151  putative methyl-accepting chemotaxis sensory transducer  32.3 
 
 
656 aa  69.7  0.00000000007  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_008390  Bamb_0171  methyl-accepting chemotaxis sensory transducer  32.91 
 
 
648 aa  70.1  0.00000000007  Burkholderia ambifaria AMMD  Bacteria  normal  0.451768  n/a   
 
 
-
 
NC_013522  Taci_1453  methyl-accepting chemotaxis sensory transducer  45.1 
 
 
597 aa  69.7  0.00000000008  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_009456  VC0395_0713  methyl-accepting chemotaxis protein  35.42 
 
 
473 aa  69.7  0.00000000008  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_013922  Nmag_2639  methyl-accepting chemotaxis sensory transducer  37.38 
 
 
864 aa  69.7  0.00000000008  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_008609  Ppro_2590  methyl-accepting chemotaxis sensory transducer  37.3 
 
 
675 aa  69.7  0.00000000008  Pelobacter propionicus DSM 2379  Bacteria  normal  0.182127  n/a   
 
 
-
 
NC_011830  Dhaf_1521  methyl-accepting chemotaxis sensory transducer  38.24 
 
 
273 aa  69.7  0.00000000009  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.0000000000656288  n/a   
 
 
-
 
NC_007520  Tcr_0570  methyl-accepting chemotaxis sensory transducer  45 
 
 
674 aa  69.7  0.00000000009  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_007952  Bxe_B2682  methyl-accepting chemotaxis sensory transducer  34.18 
 
 
580 aa  69.7  0.00000000009  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_013385  Adeg_1963  methyl-accepting chemotaxis sensory transducer  43.62 
 
 
539 aa  69.3  0.0000000001  Ammonifex degensii KC4  Bacteria  normal  0.805375  n/a   
 
 
-
 
NC_009253  Dred_0620  methyl-accepting chemotaxis sensory transducer  44.57 
 
 
512 aa  68.9  0.0000000001  Desulfotomaculum reducens MI-1  Bacteria  unclonable  0.00000106495  n/a   
 
 
-
 
NC_009253  Dred_2636  methyl-accepting chemotaxis sensory transducer  30.82 
 
 
367 aa  69.3  0.0000000001  Desulfotomaculum reducens MI-1  Bacteria  normal  0.324426  n/a   
 
 
-
 
NC_006274  BCZK5120  methyl-accepting chemotaxis protein, C-terminal region  26.25 
 
 
433 aa  69.3  0.0000000001  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_32370  methyl-accepting chemotaxis protein  41.35 
 
 
531 aa  68.9  0.0000000001  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_007643  Rru_A0718  chemotaxis sensory transducer  50 
 
 
669 aa  69.3  0.0000000001  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.845917  n/a   
 
 
-
 
NC_013522  Taci_0285  methyl-accepting chemotaxis sensory transducer  37.14 
 
 
411 aa  69.3  0.0000000001  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_007925  RPC_2846  methyl-accepting chemotaxis sensory transducer  49.3 
 
 
565 aa  68.9  0.0000000001  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.430745  normal 
 
 
-
 
NC_013093  Amir_2197  methyl-accepting chemotaxis sensory transducer  36.73 
 
 
522 aa  69.3  0.0000000001  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_1181  methyl-accepting chemotaxis sensory transducer  48.05 
 
 
621 aa  68.9  0.0000000001  Desulfotomaculum reducens MI-1  Bacteria  decreased coverage  0.00022904  n/a   
 
 
-
 
NC_010681  Bphyt_2259  methyl-accepting chemotaxis sensory transducer  34.91 
 
 
588 aa  69.3  0.0000000001  Burkholderia phytofirmans PsJN  Bacteria  normal  0.131825  normal  0.497854 
 
 
-
 
NC_010184  BcerKBAB4_5217  methyl-accepting chemotaxis sensory transducer  26.92 
 
 
432 aa  68.9  0.0000000001  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
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