More than 300 homologs were found in PanDaTox collection
for query gene Tmel_1516 on replicon NC_009616
Organism: Thermosipho melanesiensis BI429



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009616  Tmel_1516  two component transcriptional regulator  100 
 
 
218 aa  430  1e-120  Thermosipho melanesiensis BI429  Bacteria  normal  0.346089  n/a   
 
 
-
 
NC_009718  Fnod_0785  two component transcriptional regulator  61.64 
 
 
229 aa  254  7e-67  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.0635827  n/a   
 
 
-
 
NC_011661  Dtur_0154  two component transcriptional regulator, winged helix family  55.09 
 
 
220 aa  214  9.999999999999999e-55  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.443854  n/a   
 
 
-
 
NC_010003  Pmob_0095  two component transcriptional regulator  49.54 
 
 
224 aa  193  2e-48  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_009380  Strop_2130  response regulator receiver  41.26 
 
 
252 aa  188  5e-47  Salinispora tropica CNB-440  Bacteria  normal  0.539517  hitchhiker  0.00279069 
 
 
-
 
NC_008699  Noca_3695  response regulator receiver  40.09 
 
 
236 aa  188  5.999999999999999e-47  Nocardioides sp. JS614  Bacteria  normal  0.795948  n/a   
 
 
-
 
NC_009953  Sare_2277  two component transcriptional regulator  41.26 
 
 
248 aa  188  5.999999999999999e-47  Salinispora arenicola CNS-205  Bacteria  normal  0.113906  normal  0.0109188 
 
 
-
 
NC_009565  TBFG_11051  two component system transcriptional regulator trcR  42.15 
 
 
257 aa  187  1e-46  Mycobacterium tuberculosis F11  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_0321  two component transcriptional regulator  39.73 
 
 
406 aa  185  6e-46  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_3017  two component transcriptional regulator  44.09 
 
 
225 aa  184  8e-46  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_3036  two component transcriptional regulator, winged helix family  42.34 
 
 
273 aa  184  9e-46  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.106658  normal 
 
 
-
 
NC_009953  Sare_0219  two component transcriptional regulator  41.52 
 
 
237 aa  180  2e-44  Salinispora arenicola CNS-205  Bacteria  normal  0.127265  hitchhiker  0.00333518 
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  42.92 
 
 
224 aa  179  2.9999999999999997e-44  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_013525  Tter_1435  two component transcriptional regulator, winged helix family  42.73 
 
 
233 aa  177  1e-43  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_008541  Arth_0655  two component transcriptional regulator  40.72 
 
 
246 aa  177  2e-43  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1505  response regulator receiver  45.87 
 
 
219 aa  174  9.999999999999999e-43  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.404603  n/a   
 
 
-
 
NC_009487  SaurJH9_1476  two component transcriptional regulator  45.87 
 
 
219 aa  174  9.999999999999999e-43  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_011886  Achl_0804  two component transcriptional regulator, winged helix family  39.37 
 
 
246 aa  173  1.9999999999999998e-42  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_005945  BAS2056  DNA-binding response regulator  42.79 
 
 
227 aa  172  1.9999999999999998e-42  Bacillus anthracis str. Sterne  Bacteria  normal  0.413172  n/a   
 
 
-
 
NC_007530  GBAA_2212  DNA-binding response regulator  42.79 
 
 
227 aa  172  1.9999999999999998e-42  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_2240  DNA-binding response regulator  42.79 
 
 
227 aa  172  1.9999999999999998e-42  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  2.85177e-28 
 
 
-
 
NC_005945  BAS2999  DNA-binding response regulator  40.91 
 
 
224 aa  172  2.9999999999999996e-42  Bacillus anthracis str. Sterne  Bacteria  normal  0.227145  n/a   
 
 
-
 
NC_007530  GBAA_3229  DNA-binding response regulator  40.91 
 
 
224 aa  172  2.9999999999999996e-42  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_32700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  39.64 
 
 
271 aa  172  2.9999999999999996e-42  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.442824  normal  0.485424 
 
 
-
 
NC_011884  Cyan7425_3411  two component transcriptional regulator, winged helix family  41.82 
 
 
224 aa  172  3.9999999999999995e-42  Cyanothece sp. PCC 7425  Bacteria  normal  0.591115  normal 
 
 
-
 
NC_011831  Cagg_3265  two component transcriptional regulator, winged helix family  41.36 
 
 
245 aa  172  3.9999999999999995e-42  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.45002  normal 
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  41.36 
 
 
224 aa  172  3.9999999999999995e-42  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_007413  Ava_0615  two component transcriptional regulator  42.01 
 
 
228 aa  172  3.9999999999999995e-42  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0841359  normal  0.719107 
 
 
-
 
NC_013093  Amir_1724  two component transcriptional regulator, winged helix family  41.44 
 
 
243 aa  172  3.9999999999999995e-42  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_008578  Acel_1449  two component transcriptional regulator  39.45 
 
 
246 aa  172  5e-42  Acidothermus cellulolyticus 11B  Bacteria  normal  0.566781  normal 
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  43.5 
 
 
230 aa  171  5.999999999999999e-42  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  41.82 
 
 
224 aa  171  5.999999999999999e-42  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  40.91 
 
 
224 aa  171  6.999999999999999e-42  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  41.36 
 
 
224 aa  171  6.999999999999999e-42  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_009921  Franean1_6496  two component transcriptional regulator  41.18 
 
 
231 aa  171  6.999999999999999e-42  Frankia sp. EAN1pec  Bacteria  hitchhiker  0.00132974  normal  0.338684 
 
 
-
 
NC_013169  Ksed_21620  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  40.09 
 
 
238 aa  170  1e-41  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.019443  normal  0.0473518 
 
 
-
 
NC_009953  Sare_4064  two component transcriptional regulator  39.55 
 
 
233 aa  170  1e-41  Salinispora arenicola CNS-205  Bacteria  normal  0.98903  normal  0.0666639 
 
 
-
 
NC_009253  Dred_0323  two component transcriptional regulator  41.82 
 
 
227 aa  170  1e-41  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4657  two component transcriptional regulator, winged helix family  36.49 
 
 
240 aa  170  2e-41  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_0904  two component transcriptional regulator, winged helix family  36.91 
 
 
254 aa  169  3e-41  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.936287  normal  0.32173 
 
 
-
 
NC_009664  Krad_3620  two component transcriptional regulator, winged helix family  40.62 
 
 
239 aa  169  3e-41  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0253056  normal  0.477246 
 
 
-
 
NC_009380  Strop_3686  response regulator receiver  40.91 
 
 
233 aa  169  3e-41  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_011830  Dhaf_1005  two component transcriptional regulator, winged helix family  41.82 
 
 
227 aa  169  3e-41  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000255449  n/a   
 
 
-
 
NC_008531  LEUM_1732  DNA-binding response regulator  43.81 
 
 
229 aa  169  3e-41  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.019008  n/a   
 
 
-
 
NC_009523  RoseRS_2290  two component transcriptional regulator  41.82 
 
 
224 aa  169  3e-41  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_2487  two component transcriptional regulator  41.82 
 
 
224 aa  169  3e-41  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.431556  normal 
 
 
-
 
NC_013946  Mrub_0302  two component transcriptional regulator, winged helix family  41.47 
 
 
221 aa  169  4e-41  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A2194  DNA-binding response regulator  41.44 
 
 
227 aa  169  4e-41  Bacillus cereus B4264  Bacteria  hitchhiker  0.00702475  n/a   
 
 
-
 
NC_009338  Mflv_1887  two component transcriptional regulator  38.39 
 
 
231 aa  168  5e-41  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.882564  normal  0.344123 
 
 
-
 
NC_011830  Dhaf_2231  two component transcriptional regulator, winged helix family  42.92 
 
 
226 aa  168  5e-41  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_012803  Mlut_04130  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  39.19 
 
 
236 aa  168  6e-41  Micrococcus luteus NCTC 2665  Bacteria  normal  0.118973  n/a   
 
 
-
 
NC_008726  Mvan_4844  two component transcriptional regulator  38.67 
 
 
231 aa  168  7e-41  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal  0.312171 
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  43.05 
 
 
256 aa  167  8e-41  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0759  two component transcriptional regulator  38.71 
 
 
223 aa  167  9e-41  Desulfotomaculum reducens MI-1  Bacteria  hitchhiker  0.00128917  n/a   
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  43.05 
 
 
230 aa  167  1e-40  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_009441  Fjoh_3400  two component transcriptional regulator  42.79 
 
 
224 aa  167  1e-40  Flavobacterium johnsoniae UW101  Bacteria  normal  0.105495  n/a   
 
 
-
 
NC_013525  Tter_1098  two component transcriptional regulator, winged helix family  39.91 
 
 
228 aa  167  1e-40  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009523  RoseRS_0805  two component transcriptional regulator  40.18 
 
 
229 aa  166  2e-40  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_1176  two component transcriptional regulator  39.73 
 
 
229 aa  165  4e-40  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.149936 
 
 
-
 
NC_007777  Francci3_0234  two component transcriptional regulator  36.04 
 
 
242 aa  165  4e-40  Frankia sp. CcI3  Bacteria  normal  normal  0.925989 
 
 
-
 
NC_008347  Mmar10_0483  two component transcriptional regulator  40.36 
 
 
229 aa  165  4e-40  Maricaulis maris MCS10  Bacteria  normal  0.342081  normal 
 
 
-
 
NC_010816  BLD_0005  response regulator  39.83 
 
 
243 aa  165  4e-40  Bifidobacterium longum DJO10A  Bacteria  normal  0.201532  n/a   
 
 
-
 
NC_014158  Tpau_3286  two component transcriptional regulator, winged helix family  39.46 
 
 
228 aa  165  5e-40  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.167791  n/a   
 
 
-
 
NC_013517  Sterm_2324  two component transcriptional regulator, winged helix family  47.25 
 
 
223 aa  165  5.9999999999999996e-40  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.237639  n/a   
 
 
-
 
NC_009921  Franean1_6588  two component transcriptional regulator  36.94 
 
 
229 aa  165  5.9999999999999996e-40  Frankia sp. EAN1pec  Bacteria  normal  0.13217  normal 
 
 
-
 
NC_013595  Sros_4916  response regulator receiver protein  39.29 
 
 
233 aa  165  5.9999999999999996e-40  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_3673  response regulator receiver  41.1 
 
 
227 aa  165  5.9999999999999996e-40  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_008578  Acel_1595  two component transcriptional regulator  35.87 
 
 
227 aa  164  6.9999999999999995e-40  Acidothermus cellulolyticus 11B  Bacteria  normal  0.526383  normal  0.570373 
 
 
-
 
NC_008148  Rxyl_0187  two component transcriptional regulator  40.72 
 
 
227 aa  164  8e-40  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008726  Mvan_4429  two component transcriptional regulator  40.99 
 
 
250 aa  164  8e-40  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.133228  normal 
 
 
-
 
NC_008146  Mmcs_4301  two component transcriptional regulator  39.01 
 
 
230 aa  164  9e-40  Mycobacterium sp. MCS  Bacteria  normal  0.681825  n/a   
 
 
-
 
NC_008705  Mkms_4387  two component transcriptional regulator  39.01 
 
 
230 aa  164  9e-40  Mycobacterium sp. KMS  Bacteria  normal  0.0316317  normal 
 
 
-
 
NC_009077  Mjls_4681  two component transcriptional regulator  39.01 
 
 
230 aa  164  9e-40  Mycobacterium sp. JLS  Bacteria  normal  normal  0.354926 
 
 
-
 
NC_013235  Namu_4688  two component transcriptional regulator, winged helix family  41.89 
 
 
252 aa  164  1.0000000000000001e-39  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_008146  Mmcs_3926  two component transcriptional regulator  40.72 
 
 
254 aa  164  1.0000000000000001e-39  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_4000  two component transcriptional regulator  40.72 
 
 
254 aa  164  1.0000000000000001e-39  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_009077  Mjls_3941  two component transcriptional regulator  40.72 
 
 
254 aa  164  1.0000000000000001e-39  Mycobacterium sp. JLS  Bacteria  normal  normal  0.0990172 
 
 
-
 
NC_013757  Gobs_2351  two component transcriptional regulator, winged helix family  40.18 
 
 
231 aa  163  2.0000000000000002e-39  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.274912  n/a   
 
 
-
 
NC_013124  Afer_0558  two component transcriptional regulator, winged helix family  38.46 
 
 
237 aa  163  2.0000000000000002e-39  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_07910  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  40.99 
 
 
239 aa  163  2.0000000000000002e-39  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_011126  HY04AAS1_1151  two component transcriptional regulator, winged helix family  44.55 
 
 
225 aa  163  2.0000000000000002e-39  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_8879  response regulator receiver protein  37.39 
 
 
235 aa  163  2.0000000000000002e-39  Streptosporangium roseum DSM 43021  Bacteria  normal  0.103439  normal 
 
 
-
 
NC_014212  Mesil_2637  two component transcriptional regulator, winged helix family  44.04 
 
 
227 aa  163  2.0000000000000002e-39  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_009675  Anae109_4159  two component transcriptional regulator  37.61 
 
 
230 aa  163  2.0000000000000002e-39  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.667277  normal  0.0359145 
 
 
-
 
NC_008726  Mvan_2296  two component transcriptional regulator  36.77 
 
 
255 aa  163  2.0000000000000002e-39  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.398969  normal  0.240289 
 
 
-
 
NC_011898  Ccel_2106  two component transcriptional regulator, winged helix family  45.29 
 
 
238 aa  162  3e-39  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_08590  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  38.53 
 
 
239 aa  162  3e-39  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.857083 
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  42.73 
 
 
223 aa  162  3e-39  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  40 
 
 
235 aa  162  3e-39  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013530  Xcel_2937  two component transcriptional regulator, winged helix family  38.77 
 
 
243 aa  162  3e-39  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_0784  two component transcriptional regulator  40.54 
 
 
239 aa  162  3e-39  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_8872  response regulator receiver protein  38.91 
 
 
234 aa  162  3e-39  Streptosporangium roseum DSM 43021  Bacteria  normal  0.347509  normal 
 
 
-
 
NC_009767  Rcas_4445  two component transcriptional regulator  40.72 
 
 
229 aa  162  3e-39  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.14031 
 
 
-
 
NC_013216  Dtox_3055  two component transcriptional regulator, winged helix family  41.63 
 
 
227 aa  162  4.0000000000000004e-39  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.703147  hitchhiker  0.000223036 
 
 
-
 
NC_013947  Snas_5144  two component transcriptional regulator, winged helix family  39.73 
 
 
236 aa  162  4.0000000000000004e-39  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.204078  normal  0.858106 
 
 
-
 
NC_013172  Bfae_20650  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  39.45 
 
 
231 aa  162  5.0000000000000005e-39  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0260682  n/a   
 
 
-
 
NC_009523  RoseRS_0761  two component transcriptional regulator  40.72 
 
 
229 aa  162  5.0000000000000005e-39  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.179681 
 
 
-
 
NC_010338  Caul_4546  two component transcriptional regulator  40.54 
 
 
230 aa  162  5.0000000000000005e-39  Caulobacter sp. K31  Bacteria  normal  normal  0.281853 
 
 
-
 
NC_007760  Adeh_0411  two component transcriptional regulator  38.05 
 
 
230 aa  161  6e-39  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_013501  Rmar_0987  two component transcriptional regulator, winged helix family  40.09 
 
 
233 aa  161  6e-39  Rhodothermus marinus DSM 4252  Bacteria  normal  0.195539  n/a   
 
 
-
 
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