164 homologs were found in PanDaTox collection
for query gene M446_5444 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_5444  XRE family plasmid maintenance system antidote protein  100 
 
 
109 aa  219  9.999999999999999e-57  Methylobacterium sp. 4-46  Bacteria  normal  0.401369  normal  0.26731 
 
 
-
 
NC_008686  Pden_1963  XRE family plasmid maintenance system antidote protein  63.22 
 
 
99 aa  109  2.0000000000000002e-23  Paracoccus denitrificans PD1222  Bacteria  normal  normal  0.0393563 
 
 
-
 
NC_011004  Rpal_1484  XRE family plasmid maintenance system antidote protein  60.92 
 
 
107 aa  108  3e-23  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007964  Nham_0578  XRE family plasmid maintenance system antidote protein  57.95 
 
 
108 aa  102  2e-21  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_007643  Rru_A2779  plasmid maintenance system antidote protein  56.82 
 
 
110 aa  101  3e-21  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.48213  n/a   
 
 
-
 
NC_007484  Noc_0571  XRE family transcriptional regulator  43.88 
 
 
107 aa  85.9  2e-16  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_007484  Noc_1291  XRE family transcriptional regulator  45.98 
 
 
98 aa  75.5  0.0000000000002  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_009800  EcHS_A2644  putative addiction module  39.33 
 
 
1365 aa  75.9  0.0000000000002  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_009511  Swit_2425  XRE family plasmid maintenance system antidote protein  40.23 
 
 
99 aa  73.2  0.000000000001  Sphingomonas wittichii RW1  Bacteria  normal  0.674074  normal  0.184436 
 
 
-
 
NC_008608  Ppro_3836  XRE family plasmid maintenance system antidote protein  41.86 
 
 
96 aa  72  0.000000000002  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_3818  XRE family plasmid maintenance system antidote protein  42.53 
 
 
94 aa  72  0.000000000003  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00442118  n/a   
 
 
-
 
NC_009943  Dole_2889  XRE family plasmid maintenance system antidote protein  40.79 
 
 
104 aa  71.2  0.000000000004  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.955801  n/a   
 
 
-
 
NC_007484  Noc_0697  XRE family transcriptional regulator  44.44 
 
 
101 aa  70.9  0.000000000006  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_009999  Sbal195_4593  XRE family plasmid maintenance system antidote protein  47.73 
 
 
1370 aa  69.3  0.00000000001  Shewanella baltica OS195  Bacteria  normal  0.387666  normal  0.556972 
 
 
-
 
NC_013889  TK90_1633  plasmid maintenance system antidote protein, XRE family  41.11 
 
 
105 aa  69.3  0.00000000001  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.0899701  normal  0.785699 
 
 
-
 
NC_011365  Gdia_2425  plasmid maintenance system antidote protein, XRE family  41.86 
 
 
99 aa  68.9  0.00000000002  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_4500  XRE family plasmid maintenance system antidote protein  42.47 
 
 
99 aa  68.9  0.00000000002  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.550402 
 
 
-
 
NC_013422  Hneap_0372  XRE family plasmid maintenance system antidote protein  42.68 
 
 
96 aa  67.8  0.00000000005  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_009511  Swit_2184  XRE family plasmid maintenance system antidote protein  37.63 
 
 
102 aa  67  0.00000000009  Sphingomonas wittichii RW1  Bacteria  normal  hitchhiker  0.00000446782 
 
 
-
 
NC_009654  Mmwyl1_2491  XRE family plasmid maintenance system antidote protein  41.3 
 
 
96 aa  67  0.00000000009  Marinomonas sp. MWYL1  Bacteria  normal  0.289319  normal 
 
 
-
 
NC_013422  Hneap_1633  plasmid maintenance system antidote protein, XRE family  43.53 
 
 
96 aa  67  0.00000000009  Halothiobacillus neapolitanus c2  Bacteria  normal  0.110422  n/a   
 
 
-
 
CP001637  EcDH1_3127  plasmid maintenance system antidote protein, XRE family  40.28 
 
 
131 aa  66.2  0.0000000001  Escherichia coli DH1  Bacteria  normal  0.273977  n/a   
 
 
-
 
NC_011353  ECH74115_0576  addiction module antidote protein, HigA family  40.28 
 
 
131 aa  66.2  0.0000000001  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal 
 
 
-
 
NC_009467  Acry_3241  XRE family plasmid maintenance system antidote protein  43.59 
 
 
95 aa  66.2  0.0000000001  Acidiphilium cryptum JF-5  Bacteria  normal  0.0714927  n/a   
 
 
-
 
NC_009800  EcHS_A0560  addiction module antidote protein  40.28 
 
 
131 aa  66.2  0.0000000001  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_0522  addiction module antidote protein  40.28 
 
 
131 aa  66.6  0.0000000001  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
NC_010658  SbBS512_E0418  addiction module antidote protein, HigA family  40.28 
 
 
131 aa  66.6  0.0000000001  Shigella boydii CDC 3083-94  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_3133  XRE family plasmid maintenance system antidote protein  40.28 
 
 
131 aa  66.2  0.0000000001  Escherichia coli ATCC 8739  Bacteria  normal  0.0484556  unclonable  0.0000000122724 
 
 
-
 
CP001509  ECD_00434  predicted DNA-binding transcriptional regulator  40.28 
 
 
113 aa  65.9  0.0000000002  Escherichia coli BL21(DE3)  Bacteria  normal  0.449816  n/a   
 
 
-
 
NC_012892  B21_00439  hypothetical protein  40.28 
 
 
113 aa  65.9  0.0000000002  Escherichia coli BL21  Bacteria  normal  0.540311  n/a   
 
 
-
 
NC_013889  TK90_1105  plasmid maintenance system antidote protein, XRE family  48.61 
 
 
90 aa  64.7  0.0000000004  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.0903859  normal 
 
 
-
 
NC_011662  Tmz1t_3858  XRE family plasmid maintenance system antidote protein  43.16 
 
 
105 aa  64.3  0.0000000006  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_009943  Dole_2564  XRE family plasmid maintenance system antidote protein  30 
 
 
116 aa  63.9  0.0000000007  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.63579  n/a   
 
 
-
 
NC_008320  Shewmr7_4040  XRE family plasmid maintenance system antidote protein  43.06 
 
 
98 aa  63.5  0.0000000008  Shewanella sp. MR-7  Bacteria  normal  n/a   
 
 
-
 
NC_007484  Noc_0437  plasmid maintenance system antidote protein  43.06 
 
 
95 aa  63.5  0.000000001  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.494996  n/a   
 
 
-
 
NC_009719  Plav_0019  XRE family plasmid maintenance system antidote protein  40 
 
 
98 aa  62.8  0.000000001  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.191318  normal  0.0141037 
 
 
-
 
NC_011901  Tgr7_1105  XRE family plasmid maintenance system antidote protein  39.73 
 
 
105 aa  62.4  0.000000002  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  0.912318  n/a   
 
 
-
 
NC_007963  Csal_2342  XRE family plasmid maintenance system antidote protein  48.61 
 
 
93 aa  62.4  0.000000002  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_004349  SO_A0023  plasmid maintenance system antidote protein HigA  41.67 
 
 
99 aa  62  0.000000003  Shewanella oneidensis MR-1  Bacteria  normal  0.0227137  n/a   
 
 
-
 
NC_011060  Ppha_2031  XRE family plasmid maintenance system antidote protein  30.59 
 
 
106 aa  61.6  0.000000003  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  0.65469  n/a   
 
 
-
 
NC_013173  Dbac_2571  XRE family plasmid maintenance system antidote protein  39.36 
 
 
109 aa  61.2  0.000000005  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011761  AFE_0089  DNA-binding protein, putative  42.25 
 
 
105 aa  60.8  0.000000006  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  0.993479  n/a   
 
 
-
 
NC_011206  Lferr_0091  XRE family plasmid maintenance system antidote protein  42.25 
 
 
105 aa  60.8  0.000000006  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  normal 
 
 
-
 
NC_008060  Bcen_2469  XRE family plasmid maintenance system antidote protein  41.67 
 
 
100 aa  60.5  0.000000007  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008542  Bcen2424_3083  XRE family plasmid maintenance system antidote protein  41.67 
 
 
100 aa  60.5  0.000000007  Burkholderia cenocepacia HI2424  Bacteria  normal  n/a   
 
 
-
 
NC_010508  Bcenmc03_3101  XRE family plasmid maintenance system antidote protein  41.67 
 
 
100 aa  60.8  0.000000007  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.768418 
 
 
-
 
NC_007604  Synpcc7942_2319  XRE family plasmid maintenance system antidote protein  49.12 
 
 
72 aa  60.1  0.000000009  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_007510  Bcep18194_A6433  XRE family plasmid maintenance system antidote protein  40.48 
 
 
100 aa  59.7  0.00000001  Burkholderia sp. 383  Bacteria  normal  normal  0.294261 
 
 
-
 
NC_010513  Xfasm12_1144  XRE family plasmid maintenance system antidote protein  47.95 
 
 
91 aa  58.9  0.00000002  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_010513  Xfasm12_0405  XRE family plasmid maintenance system antidote protein  47.95 
 
 
91 aa  58.9  0.00000002  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_3070  XRE family plasmid maintenance system antidote protein  40.58 
 
 
151 aa  59.3  0.00000002  Burkholderia phytofirmans PsJN  Bacteria  normal  0.314371  normal 
 
 
-
 
NC_013037  Dfer_2505  XRE family plasmid maintenance system antidote protein  26.92 
 
 
103 aa  58.9  0.00000002  Dyadobacter fermentans DSM 18053  Bacteria  hitchhiker  0.0000574166  normal 
 
 
-
 
NC_013733  Slin_6998  plasmid maintenance system antidote protein, XRE family  37.5 
 
 
95 aa  58.5  0.00000003  Spirosoma linguale DSM 74  Bacteria  normal  0.337811  normal  0.775047 
 
 
-
 
NC_007951  Bxe_A0921  hypothetical protein  39.13 
 
 
151 aa  57.8  0.00000005  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_1123  XRE family plasmid maintenance system antidote protein  40.23 
 
 
109 aa  57.8  0.00000005  Dyadobacter fermentans DSM 18053  Bacteria  decreased coverage  0.0000000000109926  normal  0.590059 
 
 
-
 
NC_007963  Csal_1677  XRE family plasmid maintenance system antidote protein  38.27 
 
 
93 aa  57.4  0.00000006  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_3183  XRE family plasmid maintenance system antidote protein  35 
 
 
113 aa  57.4  0.00000006  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.171228  n/a   
 
 
-
 
NC_011004  Rpal_2524  XRE family plasmid maintenance system antidote protein  39.74 
 
 
103 aa  57.4  0.00000007  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.0379048  n/a   
 
 
-
 
NC_012560  Avin_42030  antitoxin protein  38.75 
 
 
95 aa  57  0.00000009  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_008228  Patl_3765  XRE family plasmid maintenance system antidote protein  35.8 
 
 
97 aa  57  0.00000009  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_0672  plasmid maintenance system antidote protein  36.49 
 
 
171 aa  56.6  0.0000001  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.15068  normal  0.669698 
 
 
-
 
NC_008825  Mpe_A2823  putative plasmid maintenance system antidote protein  33.73 
 
 
167 aa  56.2  0.0000001  Methylibium petroleiphilum PM1  Bacteria  normal  normal 
 
 
-
 
NC_010577  XfasM23_0361  XRE family plasmid maintenance system antidote protein  44.44 
 
 
91 aa  55.8  0.0000002  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_1455  XRE family plasmid maintenance system antidote protein  35.21 
 
 
100 aa  55.8  0.0000002  Desulfovibrio vulgaris DP4  Bacteria  normal  0.077029  normal 
 
 
-
 
NC_013204  Elen_1062  XRE family plasmid maintenance system antidote protein  32.93 
 
 
102 aa  55.5  0.0000002  Eggerthella lenta DSM 2243  Bacteria  normal  hitchhiker  0.0000765045 
 
 
-
 
NC_009671  Oant_4678  XRE family plasmid maintenance system antidote protein  34.25 
 
 
98 aa  55.8  0.0000002  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.171358  n/a   
 
 
-
 
NC_010322  PputGB1_3643  XRE family plasmid maintenance system antidote protein  37.08 
 
 
95 aa  55.8  0.0000002  Pseudomonas putida GB-1  Bacteria  normal  0.0160538  normal 
 
 
-
 
NC_010338  Caul_3225  XRE family plasmid maintenance system antidote protein  35.62 
 
 
106 aa  55.5  0.0000002  Caulobacter sp. K31  Bacteria  normal  normal  0.114466 
 
 
-
 
NC_007643  Rru_A2019  plasmid maintenance system antidote protein  36.99 
 
 
99 aa  55.1  0.0000003  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_007643  Rru_A3068  plasmid maintenance system antidote protein  37.33 
 
 
95 aa  55.1  0.0000003  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.959159  n/a   
 
 
-
 
NC_013889  TK90_0224  plasmid maintenance system antidote protein, XRE family  35.14 
 
 
99 aa  55.1  0.0000003  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.657872  normal  0.19652 
 
 
-
 
NC_007964  Nham_2852  XRE family plasmid maintenance system antidote protein  32.05 
 
 
100 aa  55.1  0.0000003  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_008740  Maqu_3198  XRE family plasmid maintenance system antidote protein  29.21 
 
 
104 aa  55.1  0.0000003  Marinobacter aquaeolei VT8  Bacteria  normal  0.562378  n/a   
 
 
-
 
NC_011901  Tgr7_0043  XRE family plasmid maintenance system antidote protein  35.29 
 
 
99 aa  54.3  0.0000005  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_007925  RPC_1256  XRE family plasmid maintenance system antidote protein  37.35 
 
 
103 aa  53.9  0.0000007  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal  0.0149882 
 
 
-
 
NC_010002  Daci_1211  XRE family plasmid maintenance system antidote protein  29.87 
 
 
103 aa  53.9  0.0000007  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_004578  PSPTO_0422  virulence-associated protein, putative  37.5 
 
 
97 aa  53.5  0.0000009  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_007925  RPC_4745  XRE family plasmid maintenance system antidote protein  38.46 
 
 
104 aa  53.1  0.000001  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.693896  normal 
 
 
-
 
NC_007950  Bpro_5380  XRE family plasmid maintenance system antidote protein  39.19 
 
 
94 aa  53.1  0.000001  Polaromonas sp. JS666  Bacteria  normal  0.031339  hitchhiker  0.000847786 
 
 
-
 
NC_010725  Mpop_1590  XRE family plasmid maintenance system antidote protein  38.37 
 
 
107 aa  52.8  0.000001  Methylobacterium populi BJ001  Bacteria  normal  0.0352422  normal 
 
 
-
 
NC_007413  Ava_3243  plasmid maintenance system antidote protein  29.11 
 
 
102 aa  52.8  0.000002  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0211861  normal 
 
 
-
 
NC_007484  Noc_0415  putative plasmid maintenance system antidote protein VapI  40.85 
 
 
78 aa  52  0.000002  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_1125  XRE family plasmid maintenance system antidote protein  32.98 
 
 
119 aa  52.4  0.000002  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.19415 
 
 
-
 
NC_007517  Gmet_2972  XRE family plasmid maintenance system antidote protein  32.88 
 
 
101 aa  52  0.000003  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_3008  XRE family plasmid maintenance system antidote protein  36.62 
 
 
104 aa  52  0.000003  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_009656  PSPA7_5378  addiction module antidote protein  32.88 
 
 
101 aa  51.6  0.000004  Pseudomonas aeruginosa PA7  Bacteria  normal  0.369538  n/a   
 
 
-
 
NC_008009  Acid345_3424  XRE family plasmid maintenance system antidote protein  32.94 
 
 
98 aa  50.8  0.000006  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_61840  putative virulence-associated protein  32.88 
 
 
101 aa  50.8  0.000006  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  hitchhiker  0.000756673  hitchhiker  0.00808433 
 
 
-
 
NC_007925  RPC_4141  XRE family plasmid maintenance system antidote protein  28.21 
 
 
101 aa  50.4  0.000007  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.267642  normal 
 
 
-
 
NC_002947  PP_1585  antidote protein, putative  30.93 
 
 
99 aa  50.4  0.000008  Pseudomonas putida KT2440  Bacteria  normal  normal  0.315858 
 
 
-
 
NC_007778  RPB_4148  XRE family plasmid maintenance system antidote protein  28.21 
 
 
101 aa  50.4  0.000008  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.287171  normal 
 
 
-
 
NC_011004  Rpal_4828  XRE family plasmid maintenance system antidote protein  28.21 
 
 
101 aa  50.1  0.00001  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007973  Rmet_1294  XRE family plasmid maintenance system antidote protein  30.61 
 
 
127 aa  49.7  0.00001  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.000401984  normal  0.503235 
 
 
-
 
NC_007517  Gmet_3001  XRE family plasmid maintenance system antidote protein  29.27 
 
 
100 aa  48.9  0.00002  Geobacter metallireducens GS-15  Bacteria  normal  normal  0.770477 
 
 
-
 
NC_013730  Slin_2499  XRE family plasmid maintenance system antidote protein  27.03 
 
 
101 aa  49.3  0.00002  Spirosoma linguale DSM 74  Bacteria  normal  0.0881387  normal  0.214118 
 
 
-
 
NC_009512  Pput_4192  XRE family plasmid maintenance system antidote protein  29.9 
 
 
99 aa  48.9  0.00002  Pseudomonas putida F1  Bacteria  normal  0.322269  normal 
 
 
-
 
NC_010725  Mpop_3935  XRE family plasmid maintenance system antidote protein  30.67 
 
 
123 aa  48.5  0.00003  Methylobacterium populi BJ001  Bacteria  normal  normal  0.155055 
 
 
-
 
NC_007643  Rru_A2430  plasmid maintenance system antidote protein  28.21 
 
 
108 aa  48.5  0.00003  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.216096  n/a   
 
 
-
 
NC_011004  Rpal_3616  XRE family plasmid maintenance system antidote protein  31.51 
 
 
100 aa  48.5  0.00003  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.322775  n/a   
 
 
-
 
NC_011761  AFE_1754  virulence-associated protein, putative  26.97 
 
 
104 aa  48.5  0.00003  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  0.0614542  n/a   
 
 
-
 
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