266 homologs were found in PanDaTox collection
for query gene Tcur_2166 on replicon NC_013510
Organism: Thermomonospora curvata DSM 43183



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013510  Tcur_2166  HAD-superfamily hydrolase, subfamily IIA  100 
 
 
334 aa  654    Thermomonospora curvata DSM 43183  Bacteria  hitchhiker  0.000345894  n/a   
 
 
-
 
NC_014165  Tbis_2016  HAD-superfamily hydrolase  66.27 
 
 
333 aa  376  1e-103  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.0636976 
 
 
-
 
NC_013595  Sros_6062  sugar phosphatase of the HAD superfamily-like protein  66.22 
 
 
336 aa  364  1e-100  Streptosporangium roseum DSM 43021  Bacteria  normal  0.733702  normal 
 
 
-
 
NC_007333  Tfu_2038  HAD family hydrolase  60.9 
 
 
334 aa  332  4e-90  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_3034  HAD-superfamily hydrolase, subfamily IIA  56.5 
 
 
335 aa  322  5e-87  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.224813  normal  0.86283 
 
 
-
 
NC_009921  Franean1_1749  HAD family hydrolase  58.62 
 
 
366 aa  300  2e-80  Frankia sp. EAN1pec  Bacteria  normal  0.0343675  hitchhiker  0.000628636 
 
 
-
 
NC_007777  Francci3_3163  HAD family hydrolase  49.58 
 
 
449 aa  290  2e-77  Frankia sp. CcI3  Bacteria  normal  0.0117236  normal  0.303399 
 
 
-
 
NC_013757  Gobs_3015  HAD-superfamily hydrolase, subfamily IIA  58.6 
 
 
359 aa  287  2e-76  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.25557  n/a   
 
 
-
 
NC_013131  Caci_5439  HAD-superfamily hydrolase, subfamily IIA  53.37 
 
 
344 aa  278  8e-74  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_2479  HAD family hydrolase  52.9 
 
 
332 aa  272  5.000000000000001e-72  Nocardioides sp. JS614  Bacteria  normal  0.19473  n/a   
 
 
-
 
NC_008578  Acel_1250  HAD family hydrolase  51.44 
 
 
338 aa  261  1e-68  Acidothermus cellulolyticus 11B  Bacteria  normal  normal  0.395408 
 
 
-
 
NC_009953  Sare_1898  HAD family hydrolase  48.24 
 
 
340 aa  253  3e-66  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.0000214064 
 
 
-
 
NC_013521  Sked_22170  predicted sugar phosphatase of HAD superfamily  49.84 
 
 
345 aa  246  4e-64  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.368706  normal 
 
 
-
 
NC_013174  Jden_1122  HAD-superfamily hydrolase, subfamily IIA  46.11 
 
 
342 aa  240  2e-62  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.706316 
 
 
-
 
NC_008541  Arth_1514  HAD family hydrolase  45.54 
 
 
330 aa  239  4e-62  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_13640  predicted sugar phosphatase of HAD superfamily  47.1 
 
 
343 aa  238  2e-61  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_014151  Cfla_1655  HAD-superfamily hydrolase, subfamily IIA  51.85 
 
 
337 aa  236  3e-61  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0557426  normal 
 
 
-
 
NC_013530  Xcel_1338  HAD-superfamily hydrolase, subfamily IIA  48.33 
 
 
338 aa  236  5.0000000000000005e-61  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_2830  HAD-superfamily hydrolase, subfamily IIA  47.12 
 
 
675 aa  230  2e-59  Gordonia bronchialis DSM 43247  Bacteria  normal  0.31853  n/a   
 
 
-
 
NC_011886  Achl_1513  HAD-superfamily hydrolase, subfamily IIA  45.23 
 
 
329 aa  228  1e-58  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00000783822 
 
 
-
 
NC_009380  Strop_1907  HAD family hydrolase  46.93 
 
 
340 aa  225  8e-58  Salinispora tropica CNB-440  Bacteria  normal  normal  0.275606 
 
 
-
 
NC_013235  Namu_4076  Haloacid dehalogenase domain protein hydrolase  45.76 
 
 
366 aa  213  2.9999999999999995e-54  Nakamurella multipartita DSM 44233  Bacteria  normal  0.125935  normal  0.0189831 
 
 
-
 
NC_012669  Bcav_2359  HAD-superfamily hydrolase, subfamily IIA  49.48 
 
 
349 aa  212  9e-54  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0246768  hitchhiker  0.00643781 
 
 
-
 
NC_010816  BLD_0800  putative HAD superfamily sugar phosphatase  41.82 
 
 
346 aa  211  1e-53  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_3511  HAD family hydrolase  43.89 
 
 
337 aa  208  1e-52  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.540896  normal  0.0582396 
 
 
-
 
NC_013947  Snas_4443  HAD-superfamily hydrolase subfamily IIA  42.36 
 
 
360 aa  204  1e-51  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.198933  normal  0.115883 
 
 
-
 
NC_013159  Svir_25490  predicted sugar phosphatase of HAD superfamily  45.05 
 
 
336 aa  205  1e-51  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_3292  HAD family hydrolase  42.99 
 
 
337 aa  204  2e-51  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_013721  HMPREF0424_0678  HAD hydrolase, family IIA  37.94 
 
 
366 aa  204  2e-51  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_009565  TBFG_11708  phosphatase  41.82 
 
 
353 aa  199  5e-50  Mycobacterium tuberculosis F11  Bacteria  normal  0.900168  normal  0.127356 
 
 
-
 
NC_008146  Mmcs_2953  HAD family hydrolase  43.91 
 
 
334 aa  194  1e-48  Mycobacterium sp. MCS  Bacteria  normal  0.361868  n/a   
 
 
-
 
NC_008705  Mkms_2997  HAD family hydrolase  43.91 
 
 
334 aa  194  1e-48  Mycobacterium sp. KMS  Bacteria  normal  0.411928  normal  0.553212 
 
 
-
 
NC_009664  Krad_3150  HAD-superfamily hydrolase, subfamily IIA  51.12 
 
 
365 aa  194  1e-48  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.714605  normal 
 
 
-
 
NC_009077  Mjls_2968  HAD family hydrolase  43.59 
 
 
334 aa  194  2e-48  Mycobacterium sp. JLS  Bacteria  normal  0.0800557  normal  0.179686 
 
 
-
 
NC_013093  Amir_5443  HAD-superfamily hydrolase, subfamily IIA  50.39 
 
 
264 aa  191  1e-47  Actinosynnema mirum DSM 43827  Bacteria  normal  0.931975  n/a   
 
 
-
 
NC_014158  Tpau_2385  HAD-superfamily hydrolase, subfamily IIA  45.17 
 
 
316 aa  190  2.9999999999999997e-47  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_012803  Mlut_14240  haloacid dehalogenase subfamily IIA protein  46.54 
 
 
276 aa  177  2e-43  Micrococcus luteus NCTC 2665  Bacteria  hitchhiker  0.00966269  n/a   
 
 
-
 
NC_012793  GWCH70_2900  HAD-superfamily subfamily IIA hydrolase like protein  39.3 
 
 
257 aa  161  1e-38  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_1044  HAD-superfamily hydrolase, subfamily IIA  40.55 
 
 
266 aa  159  7e-38  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009523  RoseRS_1310  HAD family hydrolase  39.92 
 
 
265 aa  151  1e-35  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.300835 
 
 
-
 
NC_009674  Bcer98_3557  HAD family hydrolase  37.8 
 
 
254 aa  151  1e-35  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_07430  predicted sugar phosphatase of HAD superfamily  42.17 
 
 
274 aa  150  2e-35  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.699759  normal  0.0830184 
 
 
-
 
NC_011772  BCG9842_B0137  phosphatase,haloacid dehalogenase family  40 
 
 
254 aa  149  5e-35  Bacillus cereus G9842  Bacteria  normal  0.651243  normal 
 
 
-
 
NC_013411  GYMC61_3045  HAD-superfamily subfamily IIA hydrolase like protein  38.74 
 
 
256 aa  149  6e-35  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_005945  BAS4827  phosphatase  39.15 
 
 
254 aa  149  8e-35  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00162438  n/a   
 
 
-
 
NC_007530  GBAA_5192  phosphatase  39.15 
 
 
254 aa  149  8e-35  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.183726  n/a   
 
 
-
 
NC_003909  BCE_5096  phosphatase  39.15 
 
 
254 aa  148  1.0000000000000001e-34  Bacillus cereus ATCC 10987  Bacteria  normal  0.344211  n/a   
 
 
-
 
NC_005957  BT9727_4668  4-nitrophenylphosphatase (p-nitrophenylphosphate phosphohydrolase)  39.15 
 
 
254 aa  148  1.0000000000000001e-34  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.265618  n/a   
 
 
-
 
NC_011658  BCAH187_A5101  phosphatase,haloacid dehalogenase family  39.15 
 
 
254 aa  148  1.0000000000000001e-34  Bacillus cereus AH187  Bacteria  normal  0.348234  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4780  HAD family hydrolase  38.46 
 
 
254 aa  148  1.0000000000000001e-34  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_5063  phosphatase,haloacid dehalogenase family  39.15 
 
 
254 aa  148  1.0000000000000001e-34  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_006274  BCZK4685  4-nitrophenylphosphatase (p-nitrophenylphosphate phosphohydrolase)  39.15 
 
 
254 aa  147  2.0000000000000003e-34  Bacillus cereus E33L  Bacteria  decreased coverage  0.00000109873  n/a   
 
 
-
 
NC_011725  BCB4264_A5102  phosphatase,haloacid dehalogenase family  38.72 
 
 
254 aa  144  2e-33  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_1643  HAD family hydrolase  40.59 
 
 
265 aa  141  9.999999999999999e-33  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.664632  hitchhiker  0.00147879 
 
 
-
 
NC_009513  Lreu_0563  HAD family hydrolase  33.46 
 
 
256 aa  140  1.9999999999999998e-32  Lactobacillus reuteri DSM 20016  Bacteria  normal  0.0984026  n/a   
 
 
-
 
NC_009972  Haur_3370  HAD family hydrolase  36.22 
 
 
257 aa  132  6e-30  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.109866  n/a   
 
 
-
 
NC_013172  Bfae_15000  predicted sugar phosphatase of HAD superfamily  36.43 
 
 
276 aa  132  6.999999999999999e-30  Brachybacterium faecium DSM 4810  Bacteria  normal  0.039649  n/a   
 
 
-
 
NC_013235  Namu_1914  HAD-superfamily hydrolase, subfamily IIA  35.25 
 
 
261 aa  130  4.0000000000000003e-29  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.00534341  hitchhiker  0.000838349 
 
 
-
 
NC_002976  SERP0515  HAD superfamily hydrolase  35.16 
 
 
259 aa  129  8.000000000000001e-29  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_2607  HAD-superfamily hydrolase, subfamily IIA  41.09 
 
 
269 aa  129  8.000000000000001e-29  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal  0.988604 
 
 
-
 
NC_010627  Bphy_7446  HAD family hydrolase  37.33 
 
 
273 aa  129  8.000000000000001e-29  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_008531  LEUM_0039  HAD family sugar phosphatase  34.54 
 
 
258 aa  129  8.000000000000001e-29  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_1760  HAD family hydrolase  36.22 
 
 
269 aa  128  1.0000000000000001e-28  Thermobifida fusca YX  Bacteria  normal  0.0798453  n/a   
 
 
-
 
NC_009362  OSTLU_33094  predicted protein  28.72 
 
 
308 aa  126  6e-28  Ostreococcus lucimarinus CCE9901  Eukaryota  normal  normal 
 
 
-
 
NC_013205  Aaci_1888  HAD-superfamily hydrolase, subfamily IIA  35.16 
 
 
286 aa  125  1e-27  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.772314  n/a   
 
 
-
 
NC_009953  Sare_3248  HAD family hydrolase  34.72 
 
 
259 aa  123  4e-27  Salinispora arenicola CNS-205  Bacteria  normal  normal 
 
 
-
 
NC_009718  Fnod_0233  HAD family hydrolase  33.98 
 
 
279 aa  123  5e-27  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
NC_008530  LGAS_0444  HAD family sugar phosphatase  33.72 
 
 
260 aa  122  8e-27  Lactobacillus gasseri ATCC 33323  Bacteria  decreased coverage  0.00000000163433  normal  0.182428 
 
 
-
 
NC_013441  Gbro_0615  HAD-superfamily hydrolase, subfamily IIA  35.18 
 
 
262 aa  122  9e-27  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_009380  Strop_3022  HAD family hydrolase  34.65 
 
 
259 aa  122  9e-27  Salinispora tropica CNB-440  Bacteria  normal  0.446988  normal  0.662219 
 
 
-
 
NC_004116  SAG0892  HAD superfamily hydrolase  33.46 
 
 
256 aa  122  9.999999999999999e-27  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.65538  n/a   
 
 
-
 
NC_013530  Xcel_3145  HAD-superfamily hydrolase, subfamily IIA  33.33 
 
 
257 aa  121  9.999999999999999e-27  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.386829  n/a   
 
 
-
 
NC_008527  LACR_1254  HAD family sugar phosphatase  32.94 
 
 
257 aa  122  9.999999999999999e-27  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  0.0106686  n/a   
 
 
-
 
NC_013757  Gobs_4181  HAD-superfamily hydrolase, subfamily IIA  36.25 
 
 
260 aa  121  9.999999999999999e-27  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.646523  n/a   
 
 
-
 
NC_013131  Caci_2194  HAD-superfamily hydrolase, subfamily IIA  35.56 
 
 
259 aa  121  1.9999999999999998e-26  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.48021  normal 
 
 
-
 
NC_008532  STER_1214  HAD family sugar phosphatase  35.08 
 
 
257 aa  121  1.9999999999999998e-26  Streptococcus thermophilus LMD-9  Bacteria  decreased coverage  0.000012407  n/a   
 
 
-
 
NC_009487  SaurJH9_0928  HAD family hydrolase  35.91 
 
 
259 aa  121  1.9999999999999998e-26  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_0947  HAD family hydrolase  35.91 
 
 
259 aa  121  1.9999999999999998e-26  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_013159  Svir_34110  predicted sugar phosphatase of HAD superfamily  35.43 
 
 
264 aa  120  3e-26  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.800157  normal 
 
 
-
 
NC_013739  Cwoe_3268  HAD-superfamily hydrolase, subfamily IIA  39.5 
 
 
277 aa  120  3.9999999999999996e-26  Conexibacter woesei DSM 14684  Bacteria  normal  0.029851  normal  0.0669803 
 
 
-
 
NC_014165  Tbis_1911  HAD-superfamily hydrolase  35.27 
 
 
258 aa  119  6e-26  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.104825 
 
 
-
 
NC_014210  Ndas_2757  HAD-superfamily hydrolase, subfamily IIA  35.43 
 
 
266 aa  118  1.9999999999999998e-25  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.13214  normal 
 
 
-
 
NC_007963  Csal_0794  HAD family hydrolase  36.21 
 
 
257 aa  117  3e-25  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_4163  HAD-superfamily hydrolase, subfamily IIA  35.96 
 
 
259 aa  117  3e-25  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.81021  normal 
 
 
-
 
NC_014158  Tpau_0544  HAD-superfamily hydrolase, subfamily IIA  35.5 
 
 
261 aa  117  3.9999999999999997e-25  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_013235  Namu_3321  HAD-superfamily hydrolase, subfamily IIA  35.77 
 
 
278 aa  116  5e-25  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.00782584  hitchhiker  0.00887894 
 
 
-
 
NC_009523  RoseRS_2752  phosphoglycolate phosphatase  32.17 
 
 
268 aa  116  5e-25  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_0473  HAD-superfamily hydrolase, subfamily IIA  33.99 
 
 
262 aa  115  7.999999999999999e-25  Actinosynnema mirum DSM 43827  Bacteria  normal  0.28866  n/a   
 
 
-
 
NC_014151  Cfla_2972  HAD-superfamily hydrolase, subfamily IIA  35.96 
 
 
257 aa  115  1.0000000000000001e-24  Cellulomonas flavigena DSM 20109  Bacteria  normal  normal 
 
 
-
 
NC_010483  TRQ2_1083  HAD family hydrolase  29.77 
 
 
259 aa  114  2.0000000000000002e-24  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_008146  Mmcs_1975  HAD family hydrolase  35.53 
 
 
257 aa  114  2.0000000000000002e-24  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_2424  HAD-superfamily hydrolase, subfamily IIA  33.91 
 
 
257 aa  114  2.0000000000000002e-24  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.22995 
 
 
-
 
NC_008705  Mkms_2021  HAD family hydrolase  35.53 
 
 
257 aa  114  2.0000000000000002e-24  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_1592  HAD family hydrolase  34.93 
 
 
266 aa  114  3e-24  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_009042  PICST_55335  p-nitrophenyl phosphatase  29.59 
 
 
308 aa  114  3e-24  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  0.424742  normal  0.747519 
 
 
-
 
NC_011886  Achl_0656  HAD-superfamily hydrolase, subfamily IIA  33.77 
 
 
276 aa  113  3e-24  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_009767  Rcas_1837  phosphoglycolate phosphatase  34.75 
 
 
259 aa  113  4.0000000000000004e-24  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_009077  Mjls_1955  HAD family hydrolase  35.53 
 
 
257 aa  113  4.0000000000000004e-24  Mycobacterium sp. JLS  Bacteria  normal  normal  0.363597 
 
 
-
 
NC_013926  Aboo_1184  HAD-superfamily hydrolase, subfamily IIA  30.31 
 
 
255 aa  113  6e-24  Aciduliprofundum boonei T469  Archaea  normal  n/a   
 
 
-
 
NC_009486  Tpet_1037  HAD family hydrolase  29.77 
 
 
259 aa  113  6e-24  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
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