More than 300 homologs were found in PanDaTox collection
for query gene HMPREF0424_1290 on replicon NC_013721
Organism: Gardnerella vaginalis 409-05



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013721  HMPREF0424_1290  ABC transporter, permease protein  100 
 
 
311 aa  632  1e-180  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_013521  Sked_15070  permease component of ABC-type sugar transporter  50 
 
 
311 aa  304  2.0000000000000002e-81  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.0771026  normal 
 
 
-
 
NC_013526  Tter_2316  binding-protein-dependent transport systems inner membrane component  40.6 
 
 
313 aa  196  3e-49  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_011881  Achl_4622  binding-protein-dependent transport systems inner membrane component  38.38 
 
 
317 aa  193  3e-48  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_012669  Bcav_0321  binding-protein-dependent transport systems inner membrane component  37.13 
 
 
316 aa  191  1e-47  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_014213  Mesil_3421  binding-protein-dependent transport systems inner membrane component  36.33 
 
 
307 aa  189  7e-47  Meiothermus silvanus DSM 9946  Bacteria  normal  0.556907  normal 
 
 
-
 
NC_014213  Mesil_3227  extracellular solute-binding protein family 1  36.33 
 
 
307 aa  189  7e-47  Meiothermus silvanus DSM 9946  Bacteria  decreased coverage  0.00159401  normal  0.987884 
 
 
-
 
NC_002977  MCA1942  sugar ABC transporter, permease protein  35.09 
 
 
287 aa  187  2e-46  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0955  binding-protein-dependent transport systems inner membrane component  36.18 
 
 
291 aa  187  3e-46  Petrotoga mobilis SJ95  Bacteria  normal  0.0196347  n/a   
 
 
-
 
NC_013525  Tter_0830  binding-protein-dependent transport systems inner membrane component  33.01 
 
 
309 aa  186  4e-46  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_013411  GYMC61_2730  binding-protein-dependent transport systems inner membrane component  36.77 
 
 
300 aa  186  5e-46  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011886  Achl_3567  binding-protein-dependent transport systems inner membrane component  37.33 
 
 
309 aa  186  6e-46  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013526  Tter_2208  binding-protein-dependent transport systems inner membrane component  36.4 
 
 
306 aa  184  2.0000000000000003e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.739705  n/a   
 
 
-
 
NC_013526  Tter_2217  binding-protein-dependent transport systems inner membrane component  37.64 
 
 
305 aa  183  4.0000000000000006e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_20620  binding-protein-dependent transport systems inner membrane component  38.02 
 
 
299 aa  182  6e-45  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_3573  binding-protein-dependent transport systems inner membrane component  40.08 
 
 
353 aa  181  2e-44  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.500594  normal 
 
 
-
 
NC_013205  Aaci_1216  binding-protein-dependent transport systems inner membrane component  36.06 
 
 
315 aa  181  2e-44  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  decreased coverage  0.00000228392  n/a   
 
 
-
 
NC_011899  Hore_15550  binding-protein-dependent transport systems inner membrane component  37.2 
 
 
294 aa  180  2.9999999999999997e-44  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_29330  permease component of ABC-type sugar transporter  35.46 
 
 
321 aa  180  2.9999999999999997e-44  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_010577  XfasM23_1549  binding-protein-dependent transport systems inner membrane component  35.14 
 
 
293 aa  178  1e-43  Xylella fastidiosa M23  Bacteria  normal  0.563461  n/a   
 
 
-
 
NC_008699  Noca_4634  binding-protein-dependent transport systems inner membrane component  34.85 
 
 
292 aa  177  2e-43  Nocardioides sp. JS614  Bacteria  normal  0.219562  n/a   
 
 
-
 
NC_012669  Bcav_0311  binding-protein-dependent transport systems inner membrane component  34.21 
 
 
321 aa  177  3e-43  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_0512  binding-protein-dependent transport systems inner membrane component  35.31 
 
 
318 aa  176  3e-43  Jonesia denitrificans DSM 20603  Bacteria  hitchhiker  0.000000473727  hitchhiker  0.00124128 
 
 
-
 
NC_009616  Tmel_0691  binding-protein-dependent transport systems inner membrane component  35.79 
 
 
295 aa  175  7e-43  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_0428  binding-protein-dependent transport systems inner membrane component  33.97 
 
 
310 aa  175  8e-43  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_013521  Sked_21160  carbohydrate ABC transporter membrane protein  35.74 
 
 
314 aa  175  9e-43  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.103465  normal  0.100515 
 
 
-
 
NC_009523  RoseRS_1357  binding-protein-dependent transport systems inner membrane component  37.26 
 
 
316 aa  175  9e-43  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_2365  sugar ABC transporter, permease protein  34.32 
 
 
288 aa  174  9.999999999999999e-43  Streptosporangium roseum DSM 43021  Bacteria  normal  0.216835  normal 
 
 
-
 
NC_010513  Xfasm12_1606  ABC transporter sugar permease  37.19 
 
 
293 aa  174  9.999999999999999e-43  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_1469  binding-protein-dependent transport systems inner membrane component  34.57 
 
 
283 aa  175  9.999999999999999e-43  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_2193  binding-protein-dependent transport systems inner membrane component  33.23 
 
 
306 aa  174  1.9999999999999998e-42  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.692762  normal 
 
 
-
 
NC_013172  Bfae_29020  carbohydrate ABC transporter membrane protein  38.4 
 
 
275 aa  174  1.9999999999999998e-42  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_0377  binding-protein-dependent transport systems inner membrane component  38.34 
 
 
294 aa  174  1.9999999999999998e-42  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_011368  Rleg2_5350  binding-protein-dependent transport systems inner membrane component  38.81 
 
 
308 aa  173  2.9999999999999996e-42  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.84186  normal  0.48209 
 
 
-
 
NC_012669  Bcav_3990  binding-protein-dependent transport systems inner membrane component  36.88 
 
 
317 aa  173  2.9999999999999996e-42  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_3982  binding-protein-dependent transport systems inner membrane component  36.33 
 
 
316 aa  173  2.9999999999999996e-42  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_010001  Cphy_1390  binding-protein-dependent transport systems inner membrane component  36.03 
 
 
308 aa  173  2.9999999999999996e-42  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_1529  binding-protein-dependent transport systems inner membrane component  32.7 
 
 
318 aa  172  5.999999999999999e-42  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.165529  normal  0.149292 
 
 
-
 
NC_013172  Bfae_28370  carbohydrate ABC transporter membrane protein  34.87 
 
 
287 aa  172  5.999999999999999e-42  Brachybacterium faecium DSM 4810  Bacteria  normal  0.096742  n/a   
 
 
-
 
NC_013235  Namu_1775  binding-protein-dependent transport systems inner membrane component  36.8 
 
 
309 aa  172  9e-42  Nakamurella multipartita DSM 44233  Bacteria  normal  0.114297  normal  0.0929805 
 
 
-
 
NC_010184  BcerKBAB4_2801  binding-protein-dependent transport systems inner membrane component  38.49 
 
 
288 aa  172  9e-42  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.254018  n/a   
 
 
-
 
NC_007413  Ava_0563  binding-protein dependent transport system inner membrane protein  39.54 
 
 
294 aa  170  2e-41  Anabaena variabilis ATCC 29413  Bacteria  normal  0.22835  normal  0.0558608 
 
 
-
 
NC_009939  Dgeo_2918  ABC-type sugar transport system, permease component  35.66 
 
 
305 aa  171  2e-41  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_010001  Cphy_0527  binding-protein-dependent transport systems inner membrane component  38.17 
 
 
296 aa  171  2e-41  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.0000000283647  n/a   
 
 
-
 
NC_013526  Tter_2041  binding-protein-dependent transport systems inner membrane component  36.64 
 
 
305 aa  170  3e-41  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00457854  n/a   
 
 
-
 
NC_013521  Sked_03080  permease component of ABC-type sugar transporter  38.55 
 
 
322 aa  169  5e-41  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.151535  normal 
 
 
-
 
NC_013526  Tter_2523  binding-protein-dependent transport systems inner membrane component  33.96 
 
 
309 aa  169  5e-41  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00000000325465  n/a   
 
 
-
 
NC_013526  Tter_2292  binding-protein-dependent transport systems inner membrane component  35.19 
 
 
306 aa  169  5e-41  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_0321  binding-protein-dependent transport systems inner membrane component  38.1 
 
 
420 aa  169  6e-41  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_2833  binding-protein-dependent transport systems inner membrane component  32.45 
 
 
319 aa  169  6e-41  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0200859  normal 
 
 
-
 
NC_009616  Tmel_1015  binding-protein-dependent transport systems inner membrane component  38.58 
 
 
292 aa  169  7e-41  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A0698  putative glycerol-3-phosphate ABC transporter, permease protein  35.93 
 
 
310 aa  169  8e-41  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_3983  binding-protein-dependent transport systems inner membrane component  37.7 
 
 
302 aa  168  9e-41  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.159905  normal 
 
 
-
 
NC_012848  Rleg_4750  binding-protein-dependent transport systems inner membrane component  34.66 
 
 
299 aa  167  1e-40  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.62916  normal  0.701692 
 
 
-
 
NC_013525  Tter_1094  binding-protein-dependent transport systems inner membrane component  34.34 
 
 
307 aa  168  1e-40  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_012669  Bcav_0146  binding-protein-dependent transport systems inner membrane component  35.52 
 
 
292 aa  168  1e-40  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0896196  normal 
 
 
-
 
NC_003909  BCE_0630  glycerol-3-phosphate ABC transporter, permease protein, putative  36.24 
 
 
310 aa  167  2e-40  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_013946  Mrub_2809  binding-protein-dependent transport systems inner membrane component  38.55 
 
 
279 aa  167  2e-40  Meiothermus ruber DSM 1279  Bacteria  normal  normal  0.232459 
 
 
-
 
NC_011368  Rleg2_5336  binding-protein-dependent transport systems inner membrane component  36.67 
 
 
318 aa  167  2e-40  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.949955  normal 
 
 
-
 
NC_012669  Bcav_1506  binding-protein-dependent transport systems inner membrane component  42.21 
 
 
319 aa  167  2e-40  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.172357  normal 
 
 
-
 
NC_010184  BcerKBAB4_0481  binding-protein-dependent transport systems inner membrane component  37.08 
 
 
310 aa  167  2e-40  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_11610  permease component of ABC-type sugar transporter  32.96 
 
 
311 aa  166  2.9999999999999998e-40  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.117578  normal  0.102082 
 
 
-
 
NC_013131  Caci_4319  binding-protein-dependent transport systems inner membrane component  33.09 
 
 
312 aa  167  2.9999999999999998e-40  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.778687  hitchhiker  0.00185272 
 
 
-
 
NC_012848  Rleg_4872  binding-protein-dependent transport systems inner membrane component  32.11 
 
 
310 aa  166  4e-40  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.181942  normal  0.51159 
 
 
-
 
NC_011884  Cyan7425_0944  binding-protein-dependent transport systems inner membrane component  40.16 
 
 
290 aa  166  5e-40  Cyanothece sp. PCC 7425  Bacteria  normal  0.120711  normal  0.307929 
 
 
-
 
NC_013093  Amir_2919  binding-protein-dependent transport systems inner membrane component  36.67 
 
 
310 aa  166  5e-40  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_012848  Rleg_5053  binding-protein-dependent transport systems inner membrane component  37.73 
 
 
318 aa  166  5e-40  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0625824  normal 
 
 
-
 
NC_010483  TRQ2_0339  binding-protein-dependent transport systems inner membrane component  37.23 
 
 
420 aa  166  5.9999999999999996e-40  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_1297  binding-protein-dependent transport systems inner membrane component  36.94 
 
 
279 aa  165  6.9999999999999995e-40  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.983189  normal 
 
 
-
 
NC_011071  Smal_2682  binding-protein-dependent transport systems inner membrane component  35.4 
 
 
293 aa  165  8e-40  Stenotrophomonas maltophilia R551-3  Bacteria  normal  0.990678  normal 
 
 
-
 
NC_013947  Snas_0204  binding-protein-dependent transport systems inner membrane component  32.76 
 
 
299 aa  165  8e-40  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.497209  normal  0.169553 
 
 
-
 
NC_012669  Bcav_4197  binding-protein-dependent transport systems inner membrane component  33.08 
 
 
326 aa  165  9e-40  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.979447  normal 
 
 
-
 
NC_009523  RoseRS_2819  binding-protein-dependent transport systems inner membrane component  32.36 
 
 
315 aa  165  1.0000000000000001e-39  Roseiflexus sp. RS-1  Bacteria  normal  0.0308401  normal 
 
 
-
 
NC_011725  BCB4264_A0604  putative glycerol-3-phosphate ABC transporter, permease protein  36.33 
 
 
310 aa  165  1.0000000000000001e-39  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B4735  putative glycerol-3-phosphate ABC transporter, permease protein  36.33 
 
 
310 aa  165  1.0000000000000001e-39  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_2266  binding-protein-dependent transport systems inner membrane component  38.4 
 
 
296 aa  165  1.0000000000000001e-39  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.0000392628 
 
 
-
 
NC_006274  BCZK0480  glycerol-3-phosphate ABC transporter, permease  35.96 
 
 
310 aa  164  2.0000000000000002e-39  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2527  binding-protein-dependent transport systems inner membrane component  36.64 
 
 
309 aa  164  2.0000000000000002e-39  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.849073  n/a   
 
 
-
 
NC_013526  Tter_2302  binding-protein-dependent transport systems inner membrane component  36.6 
 
 
320 aa  164  2.0000000000000002e-39  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.253823  n/a   
 
 
-
 
NC_010571  Oter_1749  binding-protein-dependent transport systems inner membrane component  35.23 
 
 
307 aa  164  2.0000000000000002e-39  Opitutus terrae PB90-1  Bacteria  normal  0.45981  normal 
 
 
-
 
NC_011773  BCAH820_0623  putative glycerol-3-phosphate ABC transporter, permease protein  35.96 
 
 
310 aa  164  2.0000000000000002e-39  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011368  Rleg2_4663  binding-protein-dependent transport systems inner membrane component  33.57 
 
 
299 aa  163  3e-39  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.456499 
 
 
-
 
NC_008541  Arth_3147  binding-protein-dependent transport systems inner membrane component  34.75 
 
 
319 aa  163  3e-39  Arthrobacter sp. FB24  Bacteria  hitchhiker  0.00382098  n/a   
 
 
-
 
NC_005957  BT9727_0478  glycerol-3-phosphate ABC transporter, permease  35.96 
 
 
310 aa  162  5.0000000000000005e-39  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_010717  PXO_00881  ABC transporter sugar permease  36.48 
 
 
294 aa  162  5.0000000000000005e-39  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.0244413  n/a   
 
 
-
 
NC_013521  Sked_27700  permease component of ABC-type sugar transporter  34.25 
 
 
321 aa  162  6e-39  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.479477 
 
 
-
 
NC_013131  Caci_8465  binding-protein-dependent transport systems inner membrane component  31.14 
 
 
315 aa  162  6e-39  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.511569  normal  0.0740219 
 
 
-
 
NC_011981  Avi_7347  ABC transporter membrane spanning protein (sugar)  35.9 
 
 
320 aa  162  7e-39  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS0536  glycerol-3-phosphate ABC transporter permease  35.58 
 
 
310 aa  162  8.000000000000001e-39  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_0567  glycerol-3-phosphate ABC transporter permease protein  35.58 
 
 
310 aa  162  8.000000000000001e-39  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2573  binding-protein-dependent transport systems inner membrane component  33.82 
 
 
309 aa  161  1e-38  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_0382  binding-protein-dependent transport systems inner membrane component  31.31 
 
 
296 aa  161  1e-38  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_2545  binding-protein-dependent transport systems inner membrane component  31.72 
 
 
316 aa  161  1e-38  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.637107  normal  0.115222 
 
 
-
 
NC_010003  Pmob_0524  binding-protein-dependent transport systems inner membrane component  36.14 
 
 
303 aa  161  1e-38  Petrotoga mobilis SJ95  Bacteria  normal  0.693678  n/a   
 
 
-
 
NC_013745  Htur_4489  binding-protein-dependent transport systems inner membrane component  34.08 
 
 
308 aa  161  2e-38  Haloterrigena turkmenica DSM 5511  Archaea  normal  0.283214  n/a   
 
 
-
 
NC_013501  Rmar_0359  binding-protein-dependent transport systems inner membrane component  32.96 
 
 
300 aa  160  2e-38  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_2030  binding-protein-dependent transport systems inner membrane component  35 
 
 
297 aa  160  2e-38  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.185813 
 
 
-
 
NC_009664  Krad_3565  binding-protein-dependent transport systems inner membrane component  35.19 
 
 
316 aa  160  2e-38  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.702273  normal  0.0136241 
 
 
-
 
NC_013411  GYMC61_0532  binding-protein-dependent transport systems inner membrane component  37.27 
 
 
311 aa  160  2e-38  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013946  Mrub_0044  binding-protein-dependent transport systems inner membrane component  33.94 
 
 
304 aa  160  3e-38  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
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