More than 300 homologs were found in PanDaTox collection
for query gene Amir_2919 on replicon NC_013093
Organism: Actinosynnema mirum DSM 43827



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013093  Amir_2919  binding-protein-dependent transport systems inner membrane component  100 
 
 
310 aa  617  1e-176  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_011886  Achl_3567  binding-protein-dependent transport systems inner membrane component  64.94 
 
 
309 aa  407  1.0000000000000001e-112  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013131  Caci_3807  binding-protein-dependent transport systems inner membrane component  66.56 
 
 
316 aa  366  1e-100  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.922708  normal  0.915782 
 
 
-
 
NC_013172  Bfae_29020  carbohydrate ABC transporter membrane protein  58.46 
 
 
275 aa  323  2e-87  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_011981  Avi_7347  ABC transporter membrane spanning protein (sugar)  54.06 
 
 
320 aa  303  2.0000000000000002e-81  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_012848  Rleg_5053  binding-protein-dependent transport systems inner membrane component  55.02 
 
 
318 aa  303  3.0000000000000004e-81  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0625824  normal 
 
 
-
 
NC_011368  Rleg2_5336  binding-protein-dependent transport systems inner membrane component  55.34 
 
 
318 aa  302  4.0000000000000003e-81  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.949955  normal 
 
 
-
 
NC_010001  Cphy_0290  binding-protein-dependent transport systems inner membrane component  45.73 
 
 
297 aa  275  5e-73  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_4634  binding-protein-dependent transport systems inner membrane component  46.46 
 
 
292 aa  253  4.0000000000000004e-66  Nocardioides sp. JS614  Bacteria  normal  0.219562  n/a   
 
 
-
 
NC_011899  Hore_20620  binding-protein-dependent transport systems inner membrane component  39.3 
 
 
299 aa  236  3e-61  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2316  binding-protein-dependent transport systems inner membrane component  40.07 
 
 
313 aa  229  6e-59  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_0321  binding-protein-dependent transport systems inner membrane component  39.42 
 
 
316 aa  228  1e-58  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_3990  binding-protein-dependent transport systems inner membrane component  40.73 
 
 
317 aa  226  4e-58  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_014213  Mesil_3227  extracellular solute-binding protein family 1  43.07 
 
 
307 aa  222  4.9999999999999996e-57  Meiothermus silvanus DSM 9946  Bacteria  decreased coverage  0.00159401  normal  0.987884 
 
 
-
 
NC_013526  Tter_2292  binding-protein-dependent transport systems inner membrane component  44.03 
 
 
306 aa  223  4.9999999999999996e-57  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_014213  Mesil_3421  binding-protein-dependent transport systems inner membrane component  43.07 
 
 
307 aa  222  4.9999999999999996e-57  Meiothermus silvanus DSM 9946  Bacteria  normal  0.556907  normal 
 
 
-
 
NC_010001  Cphy_1390  binding-protein-dependent transport systems inner membrane component  35.02 
 
 
308 aa  218  1e-55  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_2365  sugar ABC transporter, permease protein  40.56 
 
 
288 aa  215  9e-55  Streptosporangium roseum DSM 43021  Bacteria  normal  0.216835  normal 
 
 
-
 
NC_011881  Achl_4622  binding-protein-dependent transport systems inner membrane component  38.93 
 
 
317 aa  213  3.9999999999999995e-54  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013526  Tter_2523  binding-protein-dependent transport systems inner membrane component  41.03 
 
 
309 aa  212  4.9999999999999996e-54  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00000000325465  n/a   
 
 
-
 
NC_012669  Bcav_2833  binding-protein-dependent transport systems inner membrane component  38 
 
 
319 aa  212  7.999999999999999e-54  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0200859  normal 
 
 
-
 
NC_013525  Tter_0830  binding-protein-dependent transport systems inner membrane component  39.02 
 
 
309 aa  210  2e-53  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_013526  Tter_2217  binding-protein-dependent transport systems inner membrane component  38.56 
 
 
305 aa  209  3e-53  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_013530  Xcel_0898  binding-protein-dependent transport systems inner membrane component  40 
 
 
319 aa  209  4e-53  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.14469  n/a   
 
 
-
 
NC_010320  Teth514_2200  binding-protein-dependent transport systems inner membrane component  39.38 
 
 
299 aa  209  4e-53  Thermoanaerobacter sp. X514  Bacteria  normal  0.426381  n/a   
 
 
-
 
NC_013526  Tter_2208  binding-protein-dependent transport systems inner membrane component  38.71 
 
 
306 aa  208  9e-53  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.739705  n/a   
 
 
-
 
NC_009523  RoseRS_2819  binding-protein-dependent transport systems inner membrane component  36.05 
 
 
315 aa  207  2e-52  Roseiflexus sp. RS-1  Bacteria  normal  0.0308401  normal 
 
 
-
 
NC_009939  Dgeo_2918  ABC-type sugar transport system, permease component  39.53 
 
 
305 aa  207  3e-52  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_012669  Bcav_4197  binding-protein-dependent transport systems inner membrane component  38.03 
 
 
326 aa  206  5e-52  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.979447  normal 
 
 
-
 
NC_012669  Bcav_3573  binding-protein-dependent transport systems inner membrane component  41.84 
 
 
353 aa  205  6e-52  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.500594  normal 
 
 
-
 
NC_009767  Rcas_2545  binding-protein-dependent transport systems inner membrane component  36 
 
 
316 aa  204  1e-51  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.637107  normal  0.115222 
 
 
-
 
NC_009523  RoseRS_1357  binding-protein-dependent transport systems inner membrane component  38.67 
 
 
316 aa  203  3e-51  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_010001  Cphy_0527  binding-protein-dependent transport systems inner membrane component  37.2 
 
 
296 aa  202  4e-51  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.0000000283647  n/a   
 
 
-
 
NC_013526  Tter_2041  binding-protein-dependent transport systems inner membrane component  40.43 
 
 
305 aa  202  8e-51  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00457854  n/a   
 
 
-
 
NC_013174  Jden_0512  binding-protein-dependent transport systems inner membrane component  37.01 
 
 
318 aa  201  9.999999999999999e-51  Jonesia denitrificans DSM 20603  Bacteria  hitchhiker  0.000000473727  hitchhiker  0.00124128 
 
 
-
 
NC_013235  Namu_3848  binding-protein-dependent transport systems inner membrane component  39.23 
 
 
320 aa  200  1.9999999999999998e-50  Nakamurella multipartita DSM 44233  Bacteria  normal  0.0230008  normal  0.429544 
 
 
-
 
NC_012669  Bcav_1699  binding-protein-dependent transport systems inner membrane component  37.62 
 
 
315 aa  201  1.9999999999999998e-50  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.258357  normal 
 
 
-
 
NC_013526  Tter_2511  binding-protein-dependent transport systems inner membrane component  42.4 
 
 
317 aa  199  3.9999999999999996e-50  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.10809  n/a   
 
 
-
 
NC_008541  Arth_3142  binding-protein-dependent transport systems inner membrane component  38.82 
 
 
325 aa  199  5e-50  Arthrobacter sp. FB24  Bacteria  normal  0.406302  n/a   
 
 
-
 
NC_011886  Achl_3270  binding-protein-dependent transport systems inner membrane component  38.8 
 
 
321 aa  197  1.0000000000000001e-49  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013172  Bfae_29330  permease component of ABC-type sugar transporter  38.76 
 
 
321 aa  197  3e-49  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_1506  binding-protein-dependent transport systems inner membrane component  41.45 
 
 
319 aa  196  5.000000000000001e-49  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.172357  normal 
 
 
-
 
NC_012669  Bcav_0311  binding-protein-dependent transport systems inner membrane component  34.5 
 
 
321 aa  195  8.000000000000001e-49  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_008025  Dgeo_1168  binding-protein-dependent transport systems inner membrane component  42.75 
 
 
310 aa  194  1e-48  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.155614  normal 
 
 
-
 
NC_010577  XfasM23_1549  binding-protein-dependent transport systems inner membrane component  40.07 
 
 
293 aa  195  1e-48  Xylella fastidiosa M23  Bacteria  normal  0.563461  n/a   
 
 
-
 
NC_013526  Tter_2453  binding-protein-dependent transport systems inner membrane component  34.22 
 
 
314 aa  194  2e-48  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.000000200699  n/a   
 
 
-
 
NC_011831  Cagg_0728  binding-protein-dependent transport systems inner membrane component  37.3 
 
 
313 aa  194  2e-48  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.000239391  normal 
 
 
-
 
NC_010513  Xfasm12_1606  ABC transporter sugar permease  40.07 
 
 
293 aa  194  2e-48  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_012848  Rleg_4872  binding-protein-dependent transport systems inner membrane component  37.92 
 
 
310 aa  193  3e-48  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.181942  normal  0.51159 
 
 
-
 
NC_009654  Mmwyl1_0774  binding-protein-dependent transport systems inner membrane component  36.84 
 
 
293 aa  193  3e-48  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_011368  Rleg2_5350  binding-protein-dependent transport systems inner membrane component  34.47 
 
 
308 aa  193  4e-48  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.84186  normal  0.48209 
 
 
-
 
NC_013411  GYMC61_2730  binding-protein-dependent transport systems inner membrane component  35.93 
 
 
300 aa  192  6e-48  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013205  Aaci_2047  binding-protein-dependent transport systems inner membrane component  38.89 
 
 
294 aa  191  1e-47  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.550241  n/a   
 
 
-
 
NC_012850  Rleg_3429  binding-protein-dependent transport systems inner membrane component  40.14 
 
 
307 aa  191  2e-47  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_013501  Rmar_0359  binding-protein-dependent transport systems inner membrane component  38.54 
 
 
300 aa  191  2e-47  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_05430  carbohydrate ABC transporter membrane protein  37.7 
 
 
321 aa  191  2e-47  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.0550121  normal 
 
 
-
 
NC_013526  Tter_2000  binding-protein-dependent transport systems inner membrane component  37.11 
 
 
319 aa  190  2e-47  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_1151  binding-protein-dependent transport systems inner membrane component  39.92 
 
 
314 aa  190  2.9999999999999997e-47  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.59424  n/a   
 
 
-
 
NC_013521  Sked_03080  permease component of ABC-type sugar transporter  39.57 
 
 
322 aa  189  4e-47  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.151535  normal 
 
 
-
 
NC_008541  Arth_3328  binding-protein-dependent transport systems inner membrane component  37.85 
 
 
314 aa  189  5e-47  Arthrobacter sp. FB24  Bacteria  normal  0.0166533  n/a   
 
 
-
 
NC_009667  Oant_1668  binding-protein-dependent transport systems inner membrane component  36.39 
 
 
310 aa  189  5e-47  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0955  binding-protein-dependent transport systems inner membrane component  37.59 
 
 
291 aa  189  5.999999999999999e-47  Petrotoga mobilis SJ95  Bacteria  normal  0.0196347  n/a   
 
 
-
 
NC_010816  BLD_1549  MalF-type ABC sugar transport systems permease component  32.8 
 
 
317 aa  189  7e-47  Bifidobacterium longum DJO10A  Bacteria  normal  0.649517  n/a   
 
 
-
 
NC_012669  Bcav_1533  binding-protein-dependent transport systems inner membrane component  41.67 
 
 
318 aa  189  8e-47  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.384041  normal  0.0165665 
 
 
-
 
NC_013521  Sked_27700  permease component of ABC-type sugar transporter  36.69 
 
 
321 aa  189  8e-47  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.479477 
 
 
-
 
NC_009486  Tpet_0321  binding-protein-dependent transport systems inner membrane component  38.68 
 
 
420 aa  188  9e-47  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_0944  binding-protein-dependent transport systems inner membrane component  38.49 
 
 
290 aa  188  1e-46  Cyanothece sp. PCC 7425  Bacteria  normal  0.120711  normal  0.307929 
 
 
-
 
NC_013530  Xcel_2535  binding-protein-dependent transport systems inner membrane component  39.3 
 
 
314 aa  187  1e-46  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_011886  Achl_0498  binding-protein-dependent transport systems inner membrane component  38.95 
 
 
317 aa  187  1e-46  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000449996 
 
 
-
 
NC_012669  Bcav_0828  binding-protein-dependent transport systems inner membrane component  38.13 
 
 
316 aa  188  1e-46  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal  0.194369 
 
 
-
 
NC_013525  Tter_0507  binding-protein-dependent transport systems inner membrane component  41.69 
 
 
309 aa  188  1e-46  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_011661  Dtur_0382  binding-protein-dependent transport systems inner membrane component  34.51 
 
 
296 aa  187  2e-46  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_0559  binding-protein-dependent transport systems inner membrane component  40.61 
 
 
305 aa  187  2e-46  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_3074  binding-protein-dependent transport systems inner membrane component  32.9 
 
 
314 aa  187  2e-46  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_009767  Rcas_3564  binding-protein-dependent transport systems inner membrane component  39.13 
 
 
316 aa  187  2e-46  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.264329 
 
 
-
 
NC_013521  Sked_21160  carbohydrate ABC transporter membrane protein  39.22 
 
 
314 aa  186  3e-46  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.103465  normal  0.100515 
 
 
-
 
NC_010483  TRQ2_0339  binding-protein-dependent transport systems inner membrane component  38.11 
 
 
420 aa  186  4e-46  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2302  binding-protein-dependent transport systems inner membrane component  34.72 
 
 
320 aa  186  6e-46  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.253823  n/a   
 
 
-
 
NC_012880  Dd703_2034  binding-protein-dependent transport systems inner membrane component  37.28 
 
 
296 aa  185  7e-46  Dickeya dadantii Ech703  Bacteria  normal  0.963086  n/a   
 
 
-
 
NC_012912  Dd1591_1969  binding-protein-dependent transport systems inner membrane component  37.28 
 
 
296 aa  185  7e-46  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_3122  binding-protein-dependent transport systems inner membrane component  39.02 
 
 
305 aa  185  8e-46  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.99861  hitchhiker  0.000381845 
 
 
-
 
NC_008262  CPR_0477  ABC tranporter, permease protein  32.54 
 
 
315 aa  184  1.0000000000000001e-45  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_1015  binding-protein-dependent transport systems inner membrane component  33.22 
 
 
292 aa  185  1.0000000000000001e-45  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_0796  binding-protein-dependent transport systems inner membrane component  39.39 
 
 
312 aa  185  1.0000000000000001e-45  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.633875  n/a   
 
 
-
 
NC_011661  Dtur_0377  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
294 aa  184  1.0000000000000001e-45  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_3983  binding-protein-dependent transport systems inner membrane component  39.48 
 
 
302 aa  184  2.0000000000000003e-45  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.159905  normal 
 
 
-
 
NC_014165  Tbis_2715  binding-protein-dependent transporter inner membrane component  34.6 
 
 
350 aa  184  2.0000000000000003e-45  Thermobispora bispora DSM 43833  Bacteria  normal  0.392142  normal 
 
 
-
 
NC_013526  Tter_2573  binding-protein-dependent transport systems inner membrane component  38.54 
 
 
309 aa  184  2.0000000000000003e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_0593  binding-protein-dependent transport systems inner membrane component  32.21 
 
 
308 aa  184  2.0000000000000003e-45  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.000379306  n/a   
 
 
-
 
NC_014213  Mesil_3393  binding-protein-dependent transport systems inner membrane component  37.41 
 
 
291 aa  184  2.0000000000000003e-45  Meiothermus silvanus DSM 9946  Bacteria  normal  0.199241  normal  0.935882 
 
 
-
 
NC_011071  Smal_2682  binding-protein-dependent transport systems inner membrane component  39.04 
 
 
293 aa  184  2.0000000000000003e-45  Stenotrophomonas maltophilia R551-3  Bacteria  normal  0.990678  normal 
 
 
-
 
NC_008541  Arth_3147  binding-protein-dependent transport systems inner membrane component  41.67 
 
 
319 aa  183  3e-45  Arthrobacter sp. FB24  Bacteria  hitchhiker  0.00382098  n/a   
 
 
-
 
NC_009616  Tmel_1616  binding-protein-dependent transport systems inner membrane component  39.83 
 
 
429 aa  183  3e-45  Thermosipho melanesiensis BI429  Bacteria  normal  0.225919  n/a   
 
 
-
 
NC_009565  TBFG_12077  sugar ABC transporter membrane protein  35.61 
 
 
300 aa  182  4.0000000000000006e-45  Mycobacterium tuberculosis F11  Bacteria  normal  normal 
 
 
-
 
NC_002977  MCA1942  sugar ABC transporter, permease protein  41.95 
 
 
287 aa  182  5.0000000000000004e-45  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_1907  binding-protein-dependent transport systems inner membrane component  37.28 
 
 
296 aa  182  5.0000000000000004e-45  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.0961638  n/a   
 
 
-
 
NC_009616  Tmel_0691  binding-protein-dependent transport systems inner membrane component  32.88 
 
 
295 aa  182  6e-45  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_3032  binding-protein-dependent transport systems inner membrane component  32.67 
 
 
307 aa  182  6e-45  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_0146  binding-protein-dependent transport systems inner membrane component  37.46 
 
 
292 aa  182  6e-45  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0896196  normal 
 
 
-
 
NC_012669  Bcav_1523  binding-protein-dependent transport systems inner membrane component  39.73 
 
 
321 aa  182  6e-45  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
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