More than 300 homologs were found in PanDaTox collection
for query gene Sros_8180 on replicon NC_013595
Organism: Streptosporangium roseum DSM 43021



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013595  Sros_8180  ABC transporter membrane spanning protein (proline/glycine/betaine)  100 
 
 
220 aa  417  1e-116  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_3635  binding-protein-dependent transport systems inner membrane component  62.84 
 
 
242 aa  217  1e-55  Thermomonospora curvata DSM 43183  Bacteria  normal  0.719177  n/a   
 
 
-
 
NC_014210  Ndas_0398  binding-protein-dependent transport systems inner membrane component  56.44 
 
 
300 aa  201  8e-51  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_3086  binding-protein-dependent transport systems inner membrane component  48.48 
 
 
216 aa  186  3e-46  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.450801  normal  0.132405 
 
 
-
 
NC_009664  Krad_1291  binding-protein-dependent transport systems inner membrane component  52.58 
 
 
218 aa  172  3.9999999999999995e-42  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.487608  normal  0.775388 
 
 
-
 
NC_011886  Achl_2556  binding-protein-dependent transport systems inner membrane component  50 
 
 
242 aa  168  7e-41  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.0000000940529 
 
 
-
 
NC_013235  Namu_1405  binding-protein-dependent transport systems inner membrane component  48.85 
 
 
216 aa  157  1e-37  Nakamurella multipartita DSM 44233  Bacteria  normal  normal  0.81768 
 
 
-
 
NC_008541  Arth_2841  binding-protein-dependent transport systems inner membrane component  47.89 
 
 
236 aa  155  3e-37  Arthrobacter sp. FB24  Bacteria  decreased coverage  0.00717598  n/a   
 
 
-
 
NC_008699  Noca_0453  binding-protein-dependent transport systems inner membrane component  46.15 
 
 
235 aa  151  7e-36  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_009077  Mjls_5346  binding-protein-dependent transport systems inner membrane component  44.85 
 
 
222 aa  149  3e-35  Mycobacterium sp. JLS  Bacteria  normal  0.766272  normal 
 
 
-
 
NC_008146  Mmcs_4965  binding-protein-dependent transport systems inner membrane component  44.85 
 
 
222 aa  149  3e-35  Mycobacterium sp. MCS  Bacteria  normal  0.563213  n/a   
 
 
-
 
NC_008705  Mkms_5053  binding-protein-dependent transport systems inner membrane component  44.85 
 
 
222 aa  149  3e-35  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_3264  binding-protein-dependent transport systems inner membrane component  40.47 
 
 
243 aa  149  4e-35  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.0145709 
 
 
-
 
NC_013093  Amir_6270  binding-protein-dependent transport systems inner membrane component  47.45 
 
 
218 aa  149  4e-35  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_1209  binding-protein-dependent transport systems inner membrane component  45.13 
 
 
224 aa  147  2.0000000000000003e-34  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_013169  Ksed_26250  ABC-type proline/glycine betaine transport system, permease component  45.81 
 
 
214 aa  146  2.0000000000000003e-34  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.396538  normal  0.24063 
 
 
-
 
NC_009565  TBFG_13789  osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport system permease protein proW  41.36 
 
 
229 aa  139  3.9999999999999997e-32  Mycobacterium tuberculosis F11  Bacteria  normal  normal  0.783369 
 
 
-
 
NC_013421  Pecwa_4554  binding-protein-dependent transport systems inner membrane component  43.93 
 
 
214 aa  139  3.9999999999999997e-32  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_0623  binding-protein-dependent transport systems inner membrane component  44.71 
 
 
240 aa  132  3.9999999999999996e-30  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_008726  Mvan_5599  binding-protein-dependent transport systems inner membrane component  43.89 
 
 
226 aa  131  6e-30  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_2669  binding-protein-dependent transport systems inner membrane component  41.4 
 
 
234 aa  123  2e-27  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.225849  normal  0.0541787 
 
 
-
 
NC_009953  Sare_4725  binding-protein-dependent transport systems inner membrane component  41.28 
 
 
229 aa  123  3e-27  Salinispora arenicola CNS-205  Bacteria  normal  0.949447  hitchhiker  0.000140912 
 
 
-
 
NC_009380  Strop_4290  binding-protein-dependent transport systems inner membrane component  41.28 
 
 
229 aa  121  7e-27  Salinispora tropica CNB-440  Bacteria  normal  0.918168  normal  0.593562 
 
 
-
 
NC_008148  Rxyl_0984  binding-protein-dependent transport systems inner membrane component  38.18 
 
 
236 aa  120  9.999999999999999e-27  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.660466  n/a   
 
 
-
 
NC_013521  Sked_37590  ABC-type proline/glycine betaine transport system, permease component  38.5 
 
 
238 aa  120  1.9999999999999998e-26  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_0352  binding-protein-dependent transport systems inner membrane component  39.79 
 
 
212 aa  120  1.9999999999999998e-26  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.00133912  n/a   
 
 
-
 
NC_008148  Rxyl_0578  binding-protein-dependent transport systems inner membrane component  38.01 
 
 
235 aa  119  3.9999999999999996e-26  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.0139749  n/a   
 
 
-
 
NC_013172  Bfae_30030  ABC-type proline/glycine betaine transport system, permease component  39.13 
 
 
216 aa  119  4.9999999999999996e-26  Brachybacterium faecium DSM 4810  Bacteria  normal  0.734551  n/a   
 
 
-
 
NC_009767  Rcas_2531  binding-protein-dependent transport systems inner membrane component  40.49 
 
 
213 aa  117  1.9999999999999998e-25  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.41546  hitchhiker  0.00151664 
 
 
-
 
NC_013947  Snas_1034  binding-protein-dependent transport systems inner membrane component  37.5 
 
 
227 aa  114  1.0000000000000001e-24  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.165554 
 
 
-
 
NC_013204  Elen_0084  Substrate-binding region of ABC-type glycine betaine transport system  34.87 
 
 
528 aa  113  2.0000000000000002e-24  Eggerthella lenta DSM 2243  Bacteria  normal  0.689632  normal 
 
 
-
 
NC_009523  RoseRS_1814  binding-protein-dependent transport systems inner membrane component  40.61 
 
 
213 aa  113  2.0000000000000002e-24  Roseiflexus sp. RS-1  Bacteria  normal  0.518824  normal  0.0107204 
 
 
-
 
NC_007948  Bpro_1156  binding-protein-dependent transport systems inner membrane component  35.71 
 
 
207 aa  112  4.0000000000000004e-24  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_011989  Avi_0502  ABC transporter membrane spanning protein (proline/glycine/betaine)  47.44 
 
 
216 aa  112  4.0000000000000004e-24  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_1515  Substrate-binding region of ABC-type glycine betaine transport system  27.01 
 
 
526 aa  108  9.000000000000001e-23  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.0692577  n/a   
 
 
-
 
NC_007347  Reut_A2494  binding-protein dependent transport system inner membrane protein  29.61 
 
 
216 aa  107  1e-22  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_008062  Bcen_5737  binding-protein-dependent transport systems inner membrane component  33.65 
 
 
217 aa  107  1e-22  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008544  Bcen2424_6101  binding-protein-dependent transport systems inner membrane component  33.65 
 
 
217 aa  107  1e-22  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_010512  Bcenmc03_6583  binding-protein-dependent transport systems inner membrane component  33.17 
 
 
217 aa  107  2e-22  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.0902932  normal  0.0101515 
 
 
-
 
NC_007509  Bcep18194_C7552  ABC glycinebetaine/carnitine/choline transporter, inner membrane subunit  32.69 
 
 
217 aa  105  7e-22  Burkholderia sp. 383  Bacteria  normal  normal  0.542589 
 
 
-
 
NC_008254  Meso_2979  binding-protein-dependent transport systems inner membrane component  31.25 
 
 
210 aa  103  3e-21  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_009513  Lreu_0187  binding-protein-dependent transport systems inner membrane component  31.4 
 
 
212 aa  103  3e-21  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_2259  binding-protein-dependent transport systems inner membrane component  37.56 
 
 
220 aa  101  7e-21  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.345274 
 
 
-
 
NC_012856  Rpic12D_2379  Substrate-binding region of ABC-type glycine betaine transport system  32.51 
 
 
518 aa  100  1e-20  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_003295  RSc2516  putative lipoprotein transmembrane  37.06 
 
 
520 aa  100  1e-20  Ralstonia solanacearum GMI1000  Bacteria  normal  0.2714  hitchhiker  0.00948908 
 
 
-
 
NC_004578  PSPTO_4576  glycine betaine/choline OpuC ABC transporter, permease protein  36.14 
 
 
217 aa  101  1e-20  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.28564  n/a   
 
 
-
 
NC_007005  Psyr_4250  binding-protein dependent transport system inner membrane protein  36.14 
 
 
217 aa  101  1e-20  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_011898  Ccel_3333  Substrate-binding region of ABC-type glycine betaine transport system  27.4 
 
 
524 aa  101  1e-20  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000937167  n/a   
 
 
-
 
NC_009656  PSPA7_1216  ABC transporter permease  35.48 
 
 
220 aa  100  2e-20  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_2784  Substrate-binding region of ABC-type glycine betaine transport system  33.82 
 
 
504 aa  100  2e-20  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B2993  ABC glycine betaine/L-proline transporter, inner membrane subunit  35.89 
 
 
217 aa  99.4  4e-20  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_1202  binding-protein-dependent transport systems inner membrane component  27.09 
 
 
212 aa  98.6  6e-20  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_13590  ABC transporter permease  36.31 
 
 
220 aa  98.6  7e-20  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_009727  CBUD_1923  glycine betaine transport system permease protein  31.19 
 
 
526 aa  98.2  9e-20  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_0119  substrate-binding region of ABC-type glycine betaine transport system  29.11 
 
 
523 aa  97.8  1e-19  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.000124345  n/a   
 
 
-
 
NC_007492  Pfl01_0804  binding-protein dependent transport system inner membrane protein  34.65 
 
 
217 aa  97.8  1e-19  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.141523  normal  0.643445 
 
 
-
 
NC_007973  Rmet_0801  binding-protein-dependent transport systems inner membrane component  29.13 
 
 
216 aa  97.8  1e-19  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.435209 
 
 
-
 
NC_013411  GYMC61_1174  binding-protein-dependent transport systems inner membrane component  30.77 
 
 
209 aa  97.1  2e-19  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011884  Cyan7425_4031  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
205 aa  96.7  3e-19  Cyanothece sp. PCC 7425  Bacteria  normal  hitchhiker  0.00343198 
 
 
-
 
NC_010465  YPK_2864  binding-protein-dependent transport systems inner membrane component  33.99 
 
 
384 aa  95.5  6e-19  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_010159  YpAngola_A1330  quaternary amine ABC transporter permease  33.99 
 
 
384 aa  95.5  6e-19  Yersinia pestis Angola  Bacteria  normal  normal 
 
 
-
 
NC_009708  YpsIP31758_2785  quaternary amine ABC transporter permease  33.99 
 
 
384 aa  95.5  6e-19  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_3373  Substrate-binding region of ABC-type glycine betaine transport system  34.92 
 
 
489 aa  95.1  7e-19  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_0296  binding-protein-dependent transport systems inner membrane component  30.05 
 
 
211 aa  95.1  7e-19  Geobacillus sp. WCH70  Bacteria  normal  0.4946  n/a   
 
 
-
 
NC_002976  SERP2357  amino acid ABC transporter, permease protein  29.26 
 
 
211 aa  95.1  8e-19  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_009832  Spro_1446  binding-protein-dependent transport systems inner membrane component  34.18 
 
 
386 aa  94.7  1e-18  Serratia proteamaculans 568  Bacteria  normal  0.706116  normal 
 
 
-
 
NC_004116  SAG0243  amino acid ABC transporter, permease protein  28.57 
 
 
211 aa  93.6  2e-18  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0267  quaternary amine ABC transporter periplasmic substrate-binding protein  30.69 
 
 
526 aa  94  2e-18  Coxiella burnetii RSA 331  Bacteria  normal  n/a   
 
 
-
 
NC_008261  CPF_0538  glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein  29.84 
 
 
517 aa  93.6  2e-18  Clostridium perfringens ATCC 13124  Bacteria  normal  0.863672  n/a   
 
 
-
 
NC_008262  CPR_0522  glycine betaine/carnitine/choline ABC transporter, permease/substrate-binding protein  29.84 
 
 
517 aa  93.6  2e-18  Clostridium perfringens SM101  Bacteria  normal  0.271995  n/a   
 
 
-
 
NC_013530  Xcel_1080  binding-protein-dependent transport systems inner membrane component  41.92 
 
 
207 aa  93.6  2e-18  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.311538  n/a   
 
 
-
 
NC_007644  Moth_1686  binding-protein dependent transport system inner membrane protein  32.82 
 
 
207 aa  92  7e-18  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.038351  normal  0.407571 
 
 
-
 
NC_008688  Pden_4885  binding-protein-dependent transport systems inner membrane component  30.52 
 
 
216 aa  91.7  8e-18  Paracoccus denitrificans PD1222  Bacteria  normal  normal  0.694048 
 
 
-
 
NC_011145  AnaeK_3299  Substrate-binding region of ABC-type glycine betaine transport system  34.39 
 
 
490 aa  90.9  1e-17  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_013745  Htur_4757  binding-protein-dependent transport systems inner membrane component  34.83 
 
 
228 aa  90.1  2e-17  Haloterrigena turkmenica DSM 5511  Archaea  normal  n/a   
 
 
-
 
NC_007963  Csal_2353  binding-protein-dependent transport systems inner membrane component  30.3 
 
 
220 aa  89.7  3e-17  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_011080  SNSL254_A2353  inner membrane ABC transporter permease protein YehY  33.82 
 
 
377 aa  89.4  4e-17  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  normal 
 
 
-
 
CP001509  ECD_02060  predicted transporter subunit: membrane component of ABC superfamily  32.84 
 
 
385 aa  89  5e-17  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_012892  B21_02018  hypothetical protein  32.84 
 
 
385 aa  89  5e-17  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_009800  EcHS_A2265  quaternary amine ABC transporter permease  32.84 
 
 
385 aa  89  5e-17  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_37580  ABC-type proline/glycine betaine transport system, permease component  35.98 
 
 
228 aa  88.6  6e-17  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_011353  ECH74115_3255  ABC transporter, quaternary amine uptake (QAT) family, permease protein  32.84 
 
 
385 aa  88.6  6e-17  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  hitchhiker  0.000687244 
 
 
-
 
NC_009621  Smed_5106  binding-protein-dependent transport systems inner membrane component  30.37 
 
 
220 aa  88.6  7e-17  Sinorhizobium medicae WSM419  Bacteria  normal  0.485727  normal  0.10095 
 
 
-
 
NC_009632  SaurJH1_2522  binding-protein-dependent transport systems inner membrane component  28.95 
 
 
211 aa  88.6  7e-17  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.241712  n/a   
 
 
-
 
NC_009487  SaurJH9_2474  binding-protein-dependent transport systems inner membrane component  28.95 
 
 
211 aa  88.6  7e-17  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.13842  n/a   
 
 
-
 
NC_011830  Dhaf_2803  binding-protein-dependent transport systems inner membrane component  28.9 
 
 
218 aa  88.2  8e-17  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000135531  n/a   
 
 
-
 
NC_013440  Hoch_5205  Substrate-binding region of ABC-type glycine betaine transport system  29.23 
 
 
537 aa  87.8  1e-16  Haliangium ochraceum DSM 14365  Bacteria  normal  0.057164  normal 
 
 
-
 
CP001637  EcDH1_1527  binding-protein-dependent transport systems inner membrane component  32.35 
 
 
385 aa  87.4  2e-16  Escherichia coli DH1  Bacteria  normal  0.782089  n/a   
 
 
-
 
NC_002976  SERP2030  amino acid ABC transporter, permease protein  28.95 
 
 
211 aa  87  2e-16  Staphylococcus epidermidis RP62A  Bacteria  normal  0.207242  n/a   
 
 
-
 
NC_011149  SeAg_B2309  inner membrane ABC transporter permease protein YehY  33.33 
 
 
389 aa  87  2e-16  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_010498  EcSMS35_0914  quaternary amine ABC transporter permease  32.35 
 
 
385 aa  87  2e-16  Escherichia coli SMS-3-5  Bacteria  normal  normal  0.664933 
 
 
-
 
NC_007908  Rfer_1855  binding-protein-dependent transport systems inner membrane component  35.12 
 
 
392 aa  87  2e-16  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_011083  SeHA_C2398  inner membrane ABC transporter permease YehY  33.33 
 
 
389 aa  87.4  2e-16  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  0.0918369  normal 
 
 
-
 
NC_011205  SeD_A2510  inner membrane ABC transporter permease YehY  33.33 
 
 
389 aa  87.4  2e-16  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  0.579969  normal 
 
 
-
 
NC_013510  Tcur_3634  binding-protein-dependent transport systems inner membrane component  31.63 
 
 
229 aa  87  2e-16  Thermomonospora curvata DSM 43183  Bacteria  normal  0.737383  n/a   
 
 
-
 
NC_010468  EcolC_1517  binding-protein-dependent transport systems inner membrane component  32.35 
 
 
385 aa  87  2e-16  Escherichia coli ATCC 8739  Bacteria  normal  0.89368  normal 
 
 
-
 
NC_011094  SeSA_A2402  inner membrane ABC transporter permease YehY  33.33 
 
 
389 aa  87  2e-16  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.120526  normal 
 
 
-
 
NC_013457  VEA_001529  probable inner-membrane permease  29.69 
 
 
199 aa  87  2e-16  Vibrio sp. Ex25  Bacteria  normal  0.90895  n/a   
 
 
-
 
NC_013223  Dret_0770  binding-protein-dependent transport systems inner membrane component  30.21 
 
 
222 aa  87  2e-16  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_009801  EcE24377A_2419  quaternary amine ABC transporter permease  32.35 
 
 
385 aa  86.7  3e-16  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
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