96 homologs were found in PanDaTox collection
for query gene Bfae_12410 on replicon NC_013172
Organism: Brachybacterium faecium DSM 4810



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013172  Bfae_12410  methionine synthase II (cobalamin-independent)  100 
 
 
403 aa  822    Brachybacterium faecium DSM 4810  Bacteria  hitchhiker  0.00635164  n/a   
 
 
-
 
NC_013521  Sked_37200  methionine synthase II (cobalamin-independent)  66.58 
 
 
408 aa  544  1e-153  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_009664  Krad_3475  Methionine synthase vitamin-B12 independent  65.59 
 
 
406 aa  540  9.999999999999999e-153  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_0200  Methionine synthase vitamin-B12 independent  56.86 
 
 
402 aa  468  1.0000000000000001e-131  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_013169  Ksed_04810  methionine synthase II (cobalamin-independent)  51.21 
 
 
404 aa  393  1e-108  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0581869  normal 
 
 
-
 
NC_008541  Arth_0521  methionine synthase, vitamin-B12 independent  55.43 
 
 
361 aa  392  1e-108  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_009952  Dshi_2235  putative methionine synthase vitamin-B12 independent  37.05 
 
 
378 aa  239  5e-62  Dinoroseobacter shibae DFL 12  Bacteria  normal  normal 
 
 
-
 
NC_007794  Saro_2409  methionine synthase, vitamin-B12 independent  35.44 
 
 
377 aa  233  6e-60  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_1991  methionine synthase, vitamin-B12 independent  36.01 
 
 
390 aa  229  8e-59  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_007802  Jann_1114  methionine synthase, vitamin-B12 independent  35.7 
 
 
375 aa  213  7e-54  Jannaschia sp. CCS1  Bacteria  normal  0.411336  normal  0.158114 
 
 
-
 
NC_013739  Cwoe_4393  Methionine synthase vitamin-B12 independent  32.53 
 
 
398 aa  184  2.0000000000000003e-45  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_2808  Methionine synthase II (cobalamin-independent)- like protein  31.88 
 
 
395 aa  179  9e-44  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_2812  Methionine synthase II (cobalamin-independent)- like protein  29.93 
 
 
396 aa  170  4e-41  Conexibacter woesei DSM 14684  Bacteria  normal  0.0333252  normal 
 
 
-
 
NC_009767  Rcas_2758  methionine synthase vitamin-B12 independent  31.96 
 
 
340 aa  89  1e-16  Roseiflexus castenholzii DSM 13941  Bacteria  decreased coverage  0.000302857  normal 
 
 
-
 
NC_009523  RoseRS_2516  methionine synthase, vitamin-B12 independent  32.83 
 
 
340 aa  82.8  0.000000000000009  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.57162 
 
 
-
 
NC_009832  Spro_1044  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.72 
 
 
368 aa  64.7  0.000000003  Serratia proteamaculans 568  Bacteria  normal  normal  0.131119 
 
 
-
 
NC_013456  VEA_003054  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.44 
 
 
342 aa  63.9  0.000000004  Vibrio sp. Ex25  Bacteria  normal  0.902811  n/a   
 
 
-
 
NC_008752  Aave_2779  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  27.57 
 
 
341 aa  63.9  0.000000005  Acidovorax citrulli AAC00-1  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_5267  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  27.06 
 
 
340 aa  63.5  0.000000006  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.082194  normal  0.562242 
 
 
-
 
NC_009524  PsycPRwf_2277  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.44 
 
 
342 aa  63.5  0.000000006  Psychrobacter sp. PRwf-1  Bacteria  normal  normal 
 
 
-
 
NC_009783  VIBHAR_02800  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
344 aa  63.5  0.000000006  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_007204  Psyc_0846  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.44 
 
 
345 aa  63.2  0.000000007  Psychrobacter arcticus 273-4  Bacteria  normal  0.154728  normal  0.837371 
 
 
-
 
NC_003910  CPS_1151  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
347 aa  61.6  0.00000002  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_013421  Pecwa_1367  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.44 
 
 
343 aa  61.6  0.00000002  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_1464  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
343 aa  61.2  0.00000003  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_2550  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  27.41 
 
 
341 aa  60.8  0.00000004  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.812544 
 
 
-
 
NC_007509  Bcep18194_C7369  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.88 
 
 
339 aa  60.5  0.00000005  Burkholderia sp. 383  Bacteria  normal  normal  0.276101 
 
 
-
 
NC_013171  Apre_1254  MetE protein  23.24 
 
 
385 aa  60.1  0.00000008  Anaerococcus prevotii DSM 20548  Bacteria  normal  n/a   
 
 
-
 
NC_009436  Ent638_2113  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.33 
 
 
343 aa  59.7  0.00000009  Enterobacter sp. 638  Bacteria  normal  0.46001  normal 
 
 
-
 
NC_008228  Patl_0921  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
342 aa  58.9  0.0000002  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_1232  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.47 
 
 
359 aa  58.5  0.0000002  Shewanella baltica OS223  Bacteria  normal  hitchhiker  0.00000000177412 
 
 
-
 
NC_007969  Pcryo_0902  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
355 aa  58.5  0.0000002  Psychrobacter cryohalolentis K5  Bacteria  normal  0.876069  normal 
 
 
-
 
NC_009052  Sbal_3132  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.47 
 
 
354 aa  58.5  0.0000002  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_01036  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.65 
 
 
346 aa  58.5  0.0000002  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.370026  n/a   
 
 
-
 
NC_002947  PP_2698  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
344 aa  58.5  0.0000002  Pseudomonas putida KT2440  Bacteria  normal  normal  0.260342 
 
 
-
 
NC_009954  Cmaq_0981  methionine synthase vitamin-B12 independent  26.11 
 
 
393 aa  58.5  0.0000002  Caldivirga maquilingensis IC-167  Archaea  normal  normal 
 
 
-
 
NC_009665  Shew185_3141  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.1 
 
 
359 aa  57.8  0.0000003  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_012912  Dd1591_1862  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
343 aa  58.2  0.0000003  Dickeya zeae Ech1591  Bacteria  normal  0.0209984  n/a   
 
 
-
 
NC_009997  Sbal195_3284  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.1 
 
 
354 aa  57.8  0.0000003  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_009438  Sputcn32_2762  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.1 
 
 
354 aa  57.8  0.0000003  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_3578  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.47 
 
 
355 aa  57.8  0.0000003  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008309  HS_1226  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  26.52 
 
 
343 aa  58.2  0.0000003  Haemophilus somnus 129PT  Bacteria  normal  0.406716  n/a   
 
 
-
 
NC_009832  Spro_3176  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  24.89 
 
 
343 aa  57.4  0.0000004  Serratia proteamaculans 568  Bacteria  normal  0.364781  normal 
 
 
-
 
NC_013757  Gobs_3379  Methionine synthase vitamin-B12 independent  23.86 
 
 
376 aa  56.6  0.0000007  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.101236  n/a   
 
 
-
 
NC_009441  Fjoh_3839  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.58 
 
 
343 aa  56.2  0.0000009  Flavobacterium johnsoniae UW101  Bacteria  normal  0.412292  n/a   
 
 
-
 
NC_012880  Dd703_1778  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  24.12 
 
 
343 aa  56.2  0.000001  Dickeya dadantii Ech703  Bacteria  normal  0.219442  n/a   
 
 
-
 
NC_013159  Svir_36700  methionine synthase II (cobalamin-independent)  23.36 
 
 
373 aa  55.8  0.000001  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.829252  normal  0.784973 
 
 
-
 
NC_010506  Swoo_4458  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.47 
 
 
342 aa  56.2  0.000001  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_012791  Vapar_1745  Methionine synthase vitamin-B12 independent  27.07 
 
 
373 aa  55.5  0.000002  Variovorax paradoxus S110  Bacteria  normal  0.963683  n/a   
 
 
-
 
NC_007948  Bpro_3388  methionine synthase, vitamin-B12 independent  26.2 
 
 
377 aa  55.5  0.000002  Polaromonas sp. JS666  Bacteria  normal  0.101975  normal  0.0229793 
 
 
-
 
NC_011886  Achl_1726  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25 
 
 
348 aa  54.3  0.000003  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal  0.0182289 
 
 
-
 
BN001303  ANIA_05019  Methionine synthase, vitamin-B12 independent, putative (AFU_orthologue; AFUA_3G12060)  21.72 
 
 
438 aa  54.7  0.000003  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal  0.807041 
 
 
-
 
NC_007974  Rmet_5073  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  24.32 
 
 
342 aa  54.3  0.000004  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.942078 
 
 
-
 
NC_013730  Slin_1559  Methionine synthase vitamin-B12 independent  22.7 
 
 
369 aa  53.9  0.000004  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_008686  Pden_1355  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  24.11 
 
 
345 aa  54.3  0.000004  Paracoccus denitrificans PD1222  Bacteria  normal  normal 
 
 
-
 
NC_007925  RPC_3153  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  27.52 
 
 
342 aa  53.9  0.000005  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.720863  normal 
 
 
-
 
NC_009654  Mmwyl1_0388  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.68 
 
 
355 aa  53.5  0.000006  Marinomonas sp. MWYL1  Bacteria  normal  normal  0.469919 
 
 
-
 
NC_008148  Rxyl_0841  methionine synthase (B12-independent)  25.84 
 
 
385 aa  53.1  0.000008  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
CP001800  Ssol_1385  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  25.65 
 
 
332 aa  52.8  0.00001  Sulfolobus solfataricus 98/2  Archaea  normal  0.25974  n/a   
 
 
-
 
NC_013131  Caci_4334  Methionine synthase vitamin-B12 independent  24.03 
 
 
354 aa  52  0.00002  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0520376  normal  0.182105 
 
 
-
 
NC_009714  CHAB381_1170  5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransferase  17.65 
 
 
388 aa  52  0.00002  Campylobacter hominis ATCC BAA-381  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_2475  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  25.25 
 
 
340 aa  51.6  0.00002  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_008530  LGAS_1661  hypothetical protein  23.36 
 
 
366 aa  52  0.00002  Lactobacillus gasseri ATCC 33323  Bacteria  normal  normal 
 
 
-
 
NC_009376  Pars_1072  methionine synthase, vitamin-B12 independent  23.93 
 
 
384 aa  51.6  0.00002  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  normal  0.564481 
 
 
-
 
NC_009485  BBta_2188  methionine synthase (B12-independent)  26.76 
 
 
344 aa  52  0.00002  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_009954  Cmaq_0585  methionine synthase vitamin-B12 independent  26.49 
 
 
388 aa  51.6  0.00003  Caldivirga maquilingensis IC-167  Archaea  normal  0.246635  hitchhiker  0.00634375 
 
 
-
 
NC_013922  Nmag_1089  Methionine synthase vitamin-B12 independent  22.89 
 
 
366 aa  51.2  0.00003  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_013730  Slin_5820  Methionine synthase vitamin-B12 independent  25.89 
 
 
342 aa  51.2  0.00003  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.392769 
 
 
-
 
NC_013202  Hmuk_2667  methionine synthase  24.24 
 
 
355 aa  51.2  0.00003  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal 
 
 
-
 
NC_009440  Msed_2248  methionine synthase  22.58 
 
 
331 aa  51.2  0.00003  Metallosphaera sedula DSM 5348  Archaea  normal  0.88722  normal  0.0178602 
 
 
-
 
NC_012803  Mlut_20790  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  26.96 
 
 
343 aa  50.4  0.00005  Micrococcus luteus NCTC 2665  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_1586  methionine synthase, vitamin-B12 independent  21.5 
 
 
371 aa  50.4  0.00005  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009717  Xaut_5047  2-hydroxypropyl-CoM lyase  26.32 
 
 
376 aa  50.1  0.00007  Xanthobacter autotrophicus Py2  Bacteria  normal  normal 
 
 
-
 
NC_009717  Xaut_4865  2-hydroxypropyl-CoM lyase  26.32 
 
 
376 aa  50.1  0.00007  Xanthobacter autotrophicus Py2  Bacteria  normal  normal  0.0677813 
 
 
-
 
NC_009436  Ent638_1987  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  22.41 
 
 
367 aa  49.7  0.00008  Enterobacter sp. 638  Bacteria  normal  normal  0.130415 
 
 
-
 
NC_012917  PC1_1011  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  21.73 
 
 
368 aa  48.1  0.0002  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_009513  Lreu_1081  methionine synthase, vitamin-B12 independent  21.6 
 
 
379 aa  48.9  0.0002  Lactobacillus reuteri DSM 20016  Bacteria  normal  0.351458  n/a   
 
 
-
 
NC_010525  Tneu_0945  methionine synthase vitamin-B12 independent  23.48 
 
 
384 aa  48.5  0.0002  Thermoproteus neutrophilus V24Sta  Archaea  normal  0.8649  hitchhiker  0.000170069 
 
 
-
 
NC_008701  Pisl_0030  methionine synthase, vitamin-B12 independent  23.48 
 
 
384 aa  48.5  0.0002  Pyrobaculum islandicum DSM 4184  Archaea  normal  normal 
 
 
-
 
NC_008148  Rxyl_0933  methionine synthase (B12-independent)  23.79 
 
 
369 aa  47.8  0.0003  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.254746  n/a   
 
 
-
 
NC_007958  RPD_2245  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.74 
 
 
340 aa  48.1  0.0003  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.0169459  normal  0.14656 
 
 
-
 
NC_013743  Htur_2396  Methionine synthase vitamin-B12 independent  24.39 
 
 
358 aa  47  0.0006  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013421  Pecwa_3299  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  20.99 
 
 
368 aa  47  0.0006  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_009485  BBta_5702  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  21.74 
 
 
372 aa  46.6  0.0008  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.442954 
 
 
-
 
NC_011661  Dtur_1757  methionine synthase  21.8 
 
 
342 aa  45.4  0.002  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_02700  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  28.72 
 
 
777 aa  45.1  0.002  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_007614  Nmul_A1493  hypothetical protein  25.16 
 
 
333 aa  45.4  0.002  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.574311  n/a   
 
 
-
 
NC_012912  Dd1591_3103  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  21.6 
 
 
368 aa  44.7  0.003  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_008697  Noca_4810  methionine synthase (B12-independent)  27.65 
 
 
370 aa  44.7  0.003  Nocardioides sp. JS614  Bacteria  normal  normal 
 
 
-
 
NC_009513  Lreu_1870  methionine synthase, vitamin-B12 independent  23.53 
 
 
378 aa  44.7  0.003  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_8776  MetE  23.94 
 
 
367 aa  44.3  0.004  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_008531  LEUM_1801  methionine synthase II (cobalamin-independent)  23.98 
 
 
375 aa  44.3  0.004  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  n/a   
 
 
-
 
NC_009073  Pcal_0648  methionine synthase (B12-independent)  24.57 
 
 
384 aa  43.9  0.005  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal 
 
 
-
 
NC_007778  RPB_3210  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  23.23 
 
 
340 aa  43.1  0.008  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.370481  normal 
 
 
-
 
NC_003296  RSp0676  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  21.46 
 
 
776 aa  43.1  0.009  Ralstonia solanacearum GMI1000  Bacteria  normal  0.0353438  normal  0.269425 
 
 
-
 
NC_013158  Huta_0080  methionine synthase  23.47 
 
 
350 aa  43.1  0.009  Halorhabdus utahensis DSM 12940  Archaea  normal  0.0497366  n/a   
 
 
-
 
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