83 homologs were found in PanDaTox collection
for query gene ANIA_05019 on replicon BN001303
Organism: Aspergillus nidulans FGSC A4



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
BN001303  ANIA_05019  Methionine synthase, vitamin-B12 independent, putative (AFU_orthologue; AFUA_3G12060)  100 
 
 
438 aa  911    Aspergillus nidulans FGSC A4  Eukaryota  normal  normal  0.807041 
 
 
-
 
NC_012791  Vapar_1745  Methionine synthase vitamin-B12 independent  35.89 
 
 
373 aa  240  2.9999999999999997e-62  Variovorax paradoxus S110  Bacteria  normal  0.963683  n/a   
 
 
-
 
NC_013730  Slin_1559  Methionine synthase vitamin-B12 independent  36.2 
 
 
369 aa  236  4e-61  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_007948  Bpro_3388  methionine synthase, vitamin-B12 independent  35.84 
 
 
377 aa  236  7e-61  Polaromonas sp. JS666  Bacteria  normal  0.101975  normal  0.0229793 
 
 
-
 
NC_013159  Svir_36700  methionine synthase II (cobalamin-independent)  37.28 
 
 
373 aa  235  1.0000000000000001e-60  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.829252  normal  0.784973 
 
 
-
 
NC_012912  Dd1591_3103  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  36.55 
 
 
368 aa  234  3e-60  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_1586  methionine synthase, vitamin-B12 independent  36.13 
 
 
371 aa  233  4.0000000000000004e-60  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_3379  Methionine synthase vitamin-B12 independent  34.76 
 
 
376 aa  226  9e-58  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.101236  n/a   
 
 
-
 
NC_009513  Lreu_1870  methionine synthase, vitamin-B12 independent  36.11 
 
 
378 aa  224  3e-57  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_009485  BBta_5702  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  35.2 
 
 
372 aa  223  7e-57  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.442954 
 
 
-
 
NC_007963  Csal_1563  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  35.2 
 
 
392 aa  220  3.9999999999999997e-56  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.246626  n/a   
 
 
-
 
NC_011004  Rpal_4554  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  34.92 
 
 
373 aa  219  6e-56  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_013421  Pecwa_3299  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  34.01 
 
 
368 aa  218  1e-55  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_2698  methionine synthase, vitamin-B12 independent  34.67 
 
 
373 aa  217  2.9999999999999998e-55  Chelativorans sp. BNC1  Bacteria  normal  0.0426462  n/a   
 
 
-
 
NC_012917  PC1_1011  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  33.76 
 
 
368 aa  216  5e-55  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_007958  RPD_1591  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  35.04 
 
 
372 aa  215  9.999999999999999e-55  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.442624  normal 
 
 
-
 
NC_012880  Dd703_2912  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  34.35 
 
 
368 aa  215  9.999999999999999e-55  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_009513  Lreu_1081  methionine synthase, vitamin-B12 independent  33.08 
 
 
379 aa  213  7.999999999999999e-54  Lactobacillus reuteri DSM 20016  Bacteria  normal  0.351458  n/a   
 
 
-
 
NC_007778  RPB_1584  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  34.26 
 
 
372 aa  212  1e-53  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.278871  normal 
 
 
-
 
NC_013205  Aaci_0246  Methionine synthase vitamin-B12 independent  35.75 
 
 
371 aa  211  2e-53  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.489924  n/a   
 
 
-
 
NC_008531  LEUM_1801  methionine synthase II (cobalamin-independent)  33 
 
 
375 aa  207  4e-52  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  n/a   
 
 
-
 
NC_009832  Spro_1044  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  33.33 
 
 
368 aa  206  6e-52  Serratia proteamaculans 568  Bacteria  normal  normal  0.131119 
 
 
-
 
NC_009436  Ent638_1987  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  31.54 
 
 
367 aa  202  9e-51  Enterobacter sp. 638  Bacteria  normal  normal  0.130415 
 
 
-
 
NC_008528  OEOE_1190  methionine synthase II (cobalamin-independent)  31.3 
 
 
385 aa  189  5.999999999999999e-47  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_008528  OEOE_1718  hypothetical protein  30.77 
 
 
378 aa  187  3e-46  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_007925  RPC_4159  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase  32.14 
 
 
359 aa  187  3e-46  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_012880  Dd703_3283  Methionine synthase vitamin-B12 independent  32.37 
 
 
394 aa  184  2.0000000000000003e-45  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_013203  Apar_0268  Methionine synthase vitamin-B12 independent  30.3 
 
 
375 aa  180  4e-44  Atopobium parvulum DSM 20469  Bacteria  normal  normal 
 
 
-
 
NC_008531  LEUM_1803  hypothetical protein  32.23 
 
 
375 aa  179  9e-44  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_0752  hypothetical protein  30.36 
 
 
369 aa  175  1.9999999999999998e-42  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  0.751192  n/a   
 
 
-
 
NC_008530  LGAS_1661  hypothetical protein  29.64 
 
 
366 aa  160  6e-38  Lactobacillus gasseri ATCC 33323  Bacteria  normal  normal 
 
 
-
 
NC_012880  Dd703_2926  Methionine synthase vitamin-B12 independent  26.67 
 
 
367 aa  154  4e-36  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0933  methionine synthase (B12-independent)  27.3 
 
 
369 aa  153  5.9999999999999996e-36  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.254746  n/a   
 
 
-
 
NC_012912  Dd1591_3115  Methionine synthase vitamin-B12 independent  26.14 
 
 
366 aa  136  7.000000000000001e-31  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_013171  Apre_1254  MetE protein  27.74 
 
 
385 aa  127  4.0000000000000003e-28  Anaerococcus prevotii DSM 20548  Bacteria  normal  n/a   
 
 
-
 
NC_009714  CHAB381_1170  5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransferase  26.8 
 
 
388 aa  104  3e-21  Campylobacter hominis ATCC BAA-381  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_4334  Methionine synthase vitamin-B12 independent  24.08 
 
 
354 aa  77.8  0.0000000000004  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0520376  normal  0.182105 
 
 
-
 
NC_009954  Cmaq_0585  methionine synthase vitamin-B12 independent  22.77 
 
 
388 aa  76.6  0.0000000000009  Caldivirga maquilingensis IC-167  Archaea  normal  0.246635  hitchhiker  0.00634375 
 
 
-
 
NC_013595  Sros_8776  MetE  24.04 
 
 
367 aa  69.7  0.00000000009  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_2758  methionine synthase vitamin-B12 independent  22.53 
 
 
340 aa  63.9  0.000000006  Roseiflexus castenholzii DSM 13941  Bacteria  decreased coverage  0.000302857  normal 
 
 
-
 
NC_008701  Pisl_0030  methionine synthase, vitamin-B12 independent  23.1 
 
 
384 aa  63.5  0.000000007  Pyrobaculum islandicum DSM 4184  Archaea  normal  normal 
 
 
-
 
NC_009954  Cmaq_0981  methionine synthase vitamin-B12 independent  22.63 
 
 
393 aa  60.5  0.00000006  Caldivirga maquilingensis IC-167  Archaea  normal  normal 
 
 
-
 
NC_013174  Jden_0200  Methionine synthase vitamin-B12 independent  23.91 
 
 
402 aa  59.7  0.0000001  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_009073  Pcal_0648  methionine synthase (B12-independent)  22.36 
 
 
384 aa  59.7  0.0000001  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal 
 
 
-
 
NC_009376  Pars_1072  methionine synthase, vitamin-B12 independent  22.69 
 
 
384 aa  59.3  0.0000001  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  normal  0.564481 
 
 
-
 
NC_010525  Tneu_0945  methionine synthase vitamin-B12 independent  22.33 
 
 
384 aa  58.9  0.0000002  Thermoproteus neutrophilus V24Sta  Archaea  normal  0.8649  hitchhiker  0.000170069 
 
 
-
 
NC_010815  Glov_3721  Methionine synthase vitamin-B12 independent  21.76 
 
 
365 aa  58.9  0.0000002  Geobacter lovleyi SZ  Bacteria  normal  0.0129115  normal  0.3687 
 
 
-
 
NC_009523  RoseRS_2516  methionine synthase, vitamin-B12 independent  22.74 
 
 
340 aa  58.5  0.0000002  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.57162 
 
 
-
 
NC_013521  Sked_37200  methionine synthase II (cobalamin-independent)  22.75 
 
 
408 aa  57.4  0.0000005  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_009664  Krad_3475  Methionine synthase vitamin-B12 independent  24.2 
 
 
406 aa  56.2  0.000001  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal 
 
 
-
 
NC_012560  Avin_13980  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  20.31 
 
 
763 aa  56.2  0.000001  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_1757  methionine synthase  23.66 
 
 
342 aa  55.1  0.000002  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_007794  Saro_2409  methionine synthase, vitamin-B12 independent  22.65 
 
 
377 aa  55.5  0.000002  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_2366  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  22.37 
 
 
786 aa  55.5  0.000002  Arthrobacter sp. FB24  Bacteria  normal  0.0274524  n/a   
 
 
-
 
NC_013037  Dfer_2113  Methionine synthase vitamin-B12 independent  21.67 
 
 
353 aa  55.1  0.000002  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.044306  normal  0.413093 
 
 
-
 
NC_013172  Bfae_12410  methionine synthase II (cobalamin-independent)  21.72 
 
 
403 aa  54.7  0.000004  Brachybacterium faecium DSM 4810  Bacteria  hitchhiker  0.00635164  n/a   
 
 
-
 
NC_007777  Francci3_1991  methionine synthase, vitamin-B12 independent  25.06 
 
 
390 aa  54.3  0.000004  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_010483  TRQ2_1533  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  23.66 
 
 
734 aa  54.7  0.000004  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_4393  Methionine synthase vitamin-B12 independent  22.78 
 
 
398 aa  54.3  0.000004  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1489  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  22.73 
 
 
735 aa  54.3  0.000005  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.00335848  n/a   
 
 
-
 
NC_007614  Nmul_A1493  hypothetical protein  23.35 
 
 
333 aa  53.9  0.000005  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.574311  n/a   
 
 
-
 
NC_013525  Tter_1188  5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase  21.49 
 
 
767 aa  50.4  0.00006  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_011126  HY04AAS1_1502  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  21.96 
 
 
755 aa  50.4  0.00006  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_1996  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  21.73 
 
 
754 aa  50.4  0.00007  Candidatus Desulforudis audaxviator MP104C  Bacteria  hitchhiker  0.0051517  n/a   
 
 
-
 
NC_009440  Msed_2248  methionine synthase  20.88 
 
 
331 aa  49.7  0.00009  Metallosphaera sedula DSM 5348  Archaea  normal  0.88722  normal  0.0178602 
 
 
-
 
NC_013202  Hmuk_2667  methionine synthase  23.17 
 
 
355 aa  48.9  0.0002  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal 
 
 
-
 
NC_013922  Nmag_1089  Methionine synthase vitamin-B12 independent  20.23 
 
 
366 aa  48.5  0.0003  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
CP001800  Ssol_1385  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  21.07 
 
 
332 aa  48.1  0.0003  Sulfolobus solfataricus 98/2  Archaea  normal  0.25974  n/a   
 
 
-
 
NC_014151  Cfla_0105  5-methyltetrahydropteroyltriglutamate/ homocystei neS-methyltransferase  20.27 
 
 
783 aa  48.1  0.0003  Cellulomonas flavigena DSM 20109  Bacteria  normal  normal 
 
 
-
 
NC_013132  Cpin_6481  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  24.4 
 
 
769 aa  48.1  0.0003  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.668969 
 
 
-
 
NC_008541  Arth_0521  methionine synthase, vitamin-B12 independent  25.72 
 
 
361 aa  48.1  0.0003  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_008312  Tery_0847  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  20.74 
 
 
744 aa  47.8  0.0004  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.601961 
 
 
-
 
NC_012034  Athe_2549  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  21.45 
 
 
757 aa  47.4  0.0005  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_007802  Jann_1114  methionine synthase, vitamin-B12 independent  23.85 
 
 
375 aa  47  0.0006  Jannaschia sp. CCS1  Bacteria  normal  0.411336  normal  0.158114 
 
 
-
 
NC_012029  Hlac_2108  methionine synthase  19.67 
 
 
356 aa  47.4  0.0006  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  0.112744  normal  0.0912449 
 
 
-
 
NC_009952  Dshi_2235  putative methionine synthase vitamin-B12 independent  23.23 
 
 
378 aa  47.4  0.0006  Dinoroseobacter shibae DFL 12  Bacteria  normal  normal 
 
 
-
 
NC_013422  Hneap_0642  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  19.89 
 
 
761 aa  45.4  0.002  Halothiobacillus neapolitanus c2  Bacteria  normal  0.534267  n/a   
 
 
-
 
NC_004116  SAG2049  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase  17.74 
 
 
745 aa  45.1  0.002  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
BN001303  ANIA_04443  Cobalamin-independent methionine synthase (EC 2.1.1.14) [Source:UniProtKB/TrEMBL;Acc:Q9P444]  25.89 
 
 
774 aa  45.4  0.002  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal 
 
 
-
 
NC_008346  Swol_1326  Fe-S oxidoreductase  24.41 
 
 
451 aa  44.7  0.003  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_013743  Htur_2396  Methionine synthase vitamin-B12 independent  22.3 
 
 
358 aa  44.3  0.004  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_011661  Dtur_1756  Cobalamin-independent synthase MetE domain protein  22.97 
 
 
325 aa  43.9  0.006  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_013946  Mrub_0967  5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase  18.36 
 
 
759 aa  43.5  0.008  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
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