More than 300 homologs were found in PanDaTox collection
for query gene Tmz1t_2388 on replicon NC_011667
Organism: Thauera sp. MZ1T



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011667  Tmz1t_2388  heavy metal response regulator  100 
 
 
228 aa  449  1e-125  Thauera sp. MZ1T  Bacteria  decreased coverage  0.000142984  normal  0.119734 
 
 
-
 
NC_011662  Tmz1t_2101  two component heavy metal response transcriptional regulator, winged helix family  100 
 
 
228 aa  449  1e-125  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  74.34 
 
 
225 aa  334  5.999999999999999e-91  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  70.18 
 
 
228 aa  327  9e-89  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  69.87 
 
 
232 aa  321  6e-87  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  63.72 
 
 
231 aa  296  1e-79  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  65.07 
 
 
226 aa  293  1e-78  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  64.63 
 
 
226 aa  291  8e-78  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  63.27 
 
 
224 aa  288  5.0000000000000004e-77  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  62.11 
 
 
224 aa  288  5.0000000000000004e-77  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  60.53 
 
 
229 aa  286  2e-76  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_011992  Dtpsy_2215  two component heavy metal response transcriptional regulator, winged helix family  63.27 
 
 
228 aa  286  2e-76  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_009656  PSPA7_3892  putative two-component response regulator  58.41 
 
 
229 aa  284  7e-76  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  61.16 
 
 
224 aa  284  7e-76  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_004578  PSPTO_1307  DNA-binding heavy metal response regulator  60.62 
 
 
225 aa  283  2.0000000000000002e-75  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.150056  n/a   
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  61.5 
 
 
226 aa  283  2.0000000000000002e-75  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  60.62 
 
 
225 aa  283  2.0000000000000002e-75  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  62.28 
 
 
228 aa  283  2.0000000000000002e-75  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007005  Psyr_1127  heavy metal response regulator  60.18 
 
 
225 aa  281  4.0000000000000003e-75  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.294376  normal  0.216529 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  62.72 
 
 
228 aa  282  4.0000000000000003e-75  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  61.61 
 
 
225 aa  281  5.000000000000001e-75  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  60.18 
 
 
224 aa  281  6.000000000000001e-75  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  63.16 
 
 
225 aa  281  7.000000000000001e-75  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  62.28 
 
 
228 aa  281  7.000000000000001e-75  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  61.61 
 
 
225 aa  280  1e-74  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  61.67 
 
 
226 aa  280  1e-74  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  62.72 
 
 
228 aa  280  1e-74  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  60.18 
 
 
224 aa  280  1e-74  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  62.72 
 
 
228 aa  280  1e-74  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  60.96 
 
 
226 aa  279  2e-74  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  61.23 
 
 
226 aa  278  4e-74  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  59.29 
 
 
223 aa  278  4e-74  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_45880  putative two-component response regulator  57.52 
 
 
229 aa  278  4e-74  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal  0.954426 
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  59.29 
 
 
223 aa  278  6e-74  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  61.23 
 
 
226 aa  278  6e-74  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  61.78 
 
 
225 aa  277  8e-74  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  61.78 
 
 
225 aa  277  8e-74  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  61.78 
 
 
225 aa  277  8e-74  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  63.16 
 
 
228 aa  277  1e-73  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  58.85 
 
 
223 aa  277  1e-73  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  61.4 
 
 
228 aa  276  2e-73  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  61.23 
 
 
223 aa  276  2e-73  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  58.41 
 
 
223 aa  275  3e-73  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  58.41 
 
 
223 aa  275  3e-73  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  60.79 
 
 
226 aa  275  6e-73  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_010676  Bphyt_5873  two component heavy metal response transcriptional regulator, winged helix family  61.23 
 
 
228 aa  274  9e-73  Burkholderia phytofirmans PsJN  Bacteria  normal  0.247228  normal 
 
 
-
 
NC_007952  Bxe_B2069  two component heavy metal response transcriptional regulator  61.23 
 
 
228 aa  274  9e-73  Burkholderia xenovorans LB400  Bacteria  normal  0.0102482  normal 
 
 
-
 
NC_010465  YPK_2192  two component heavy metal response transcriptional regulator  59.73 
 
 
230 aa  273  1.0000000000000001e-72  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_009708  YpsIP31758_2084  DNA-binding heavy metal response regulator  59.73 
 
 
230 aa  273  1.0000000000000001e-72  Yersinia pseudotuberculosis IP 31758  Bacteria  hitchhiker  0.000771382  n/a   
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  60.89 
 
 
225 aa  273  2.0000000000000002e-72  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_010070  Bmul_6295  two component heavy metal response transcriptional regulator  58.85 
 
 
223 aa  273  2.0000000000000002e-72  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.803537  normal  0.219108 
 
 
-
 
NC_007650  BTH_II1376  DNA-binding response regulator IrlR  61.06 
 
 
229 aa  272  3e-72  Burkholderia thailandensis E264  Bacteria  normal  0.498923  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  59.91 
 
 
225 aa  272  4.0000000000000004e-72  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_1174  two component heavy metal response transcriptional regulator  58.77 
 
 
224 aa  271  4.0000000000000004e-72  Pseudomonas mendocina ymp  Bacteria  normal  0.216853  normal 
 
 
-
 
NC_010159  YpAngola_A2480  DNA-binding heavy metal response regulator  59.73 
 
 
230 aa  271  4.0000000000000004e-72  Yersinia pestis Angola  Bacteria  hitchhiker  0.00000187636  normal  0.518539 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  60.89 
 
 
230 aa  271  5.000000000000001e-72  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_3842  two component heavy metal response transcriptional regulator  61.06 
 
 
227 aa  271  6e-72  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.67414 
 
 
-
 
NC_007511  Bcep18194_B2430  two component heavy metal response transcriptional regulator  61.06 
 
 
227 aa  271  6e-72  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  61.78 
 
 
227 aa  271  6e-72  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  61.71 
 
 
219 aa  271  6e-72  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_008061  Bcen_4683  two component heavy metal response transcriptional regulator  61.06 
 
 
228 aa  271  7e-72  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.222547  n/a   
 
 
-
 
NC_008543  Bcen2424_3680  two component heavy metal response transcriptional regulator  61.06 
 
 
228 aa  271  7e-72  Burkholderia cenocepacia HI2424  Bacteria  normal  0.224842  normal 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  57.96 
 
 
230 aa  270  1e-71  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_010070  Bmul_6173  two component heavy metal response transcriptional regulator  61.06 
 
 
228 aa  270  1e-71  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.400074 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  59.03 
 
 
223 aa  270  1e-71  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  59.65 
 
 
225 aa  270  2e-71  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_010552  BamMC406_4186  two component heavy metal response transcriptional regulator  61.23 
 
 
231 aa  270  2e-71  Burkholderia ambifaria MC40-6  Bacteria  normal  0.24384  normal  0.790942 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  59.29 
 
 
224 aa  270  2e-71  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_008391  Bamb_3708  two component heavy metal response transcriptional regulator  61.23 
 
 
231 aa  270  2e-71  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  64.04 
 
 
227 aa  270  2e-71  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_3227  two component heavy metal response transcriptional regulator  60.79 
 
 
231 aa  269  2.9999999999999997e-71  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.303749  normal  0.0627816 
 
 
-
 
NC_008061  Bcen_4076  two component heavy metal response transcriptional regulator  60.79 
 
 
231 aa  269  2.9999999999999997e-71  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0105833  n/a   
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  60.18 
 
 
225 aa  269  2.9999999999999997e-71  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_008543  Bcen2424_4290  two component heavy metal response transcriptional regulator  60.79 
 
 
231 aa  269  2.9999999999999997e-71  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  60 
 
 
223 aa  268  4e-71  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_1510  two component heavy metal response transcriptional regulator, winged helix family  57.89 
 
 
227 aa  268  5e-71  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  65.33 
 
 
242 aa  267  8e-71  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  60.44 
 
 
228 aa  267  8.999999999999999e-71  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_4389  two component heavy metal response transcriptional regulator, winged helix family  60.62 
 
 
226 aa  267  8.999999999999999e-71  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_009079  BMA10247_A1180  transcriptional activator IrlR  60.62 
 
 
229 aa  266  1e-70  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0831411  n/a   
 
 
-
 
NC_006349  BMAA1028  DNA-binding response regulator IrlR  60.62 
 
 
229 aa  266  1e-70  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0282692  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0030  DNA-binding response regulator IrlR  60.62 
 
 
229 aa  266  1e-70  Burkholderia pseudomallei 1710b  Bacteria  normal  0.122488  n/a   
 
 
-
 
NC_007511  Bcep18194_B1729  two component heavy metal response transcriptional regulator  60.35 
 
 
231 aa  267  1e-70  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_009078  BURPS1106A_A1439  transcriptional activator IrlR  60.62 
 
 
229 aa  266  1e-70  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_0402  transcriptional activator IrlR  60.62 
 
 
229 aa  266  1e-70  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0800763  n/a   
 
 
-
 
NC_009075  BURPS668_A1524  transcriptional activator protein IrlR  60.62 
 
 
229 aa  266  1e-70  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_008784  BMASAVP1_0010  transcriptional activator IrlR  60.62 
 
 
229 aa  266  1e-70  Burkholderia mallei SAVP1  Bacteria  normal  0.121051  n/a   
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  59.73 
 
 
227 aa  266  2e-70  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_007511  Bcep18194_B2768  two component heavy metal response transcriptional regulator  58.41 
 
 
223 aa  266  2e-70  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_010086  Bmul_4315  two component heavy metal response transcriptional regulator  59.47 
 
 
232 aa  265  2.9999999999999995e-70  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.767231  normal  0.644171 
 
 
-
 
NC_010625  Bphy_6519  two component heavy metal response transcriptional regulator  59.47 
 
 
228 aa  266  2.9999999999999995e-70  Burkholderia phymatum STM815  Bacteria  normal  normal  0.0435386 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  63.16 
 
 
226 aa  265  4e-70  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_0047  DNA-binding heavy metal response regulator, putative  57.46 
 
 
224 aa  265  4e-70  Pseudomonas putida KT2440  Bacteria  normal  0.116112  hitchhiker  0.00000494979 
 
 
-
 
NC_010676  Bphyt_4933  two component heavy metal response transcriptional regulator, winged helix family  56 
 
 
223 aa  265  4e-70  Burkholderia phytofirmans PsJN  Bacteria  normal  0.461594  normal  0.344735 
 
 
-
 
NC_010322  PputGB1_0061  two component heavy metal response transcriptional regulator  57.46 
 
 
224 aa  265  4e-70  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0868462 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  58.48 
 
 
226 aa  265  4e-70  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_0061  two component heavy metal response transcriptional regulator  57.46 
 
 
224 aa  265  4e-70  Pseudomonas putida F1  Bacteria  normal  0.382659  hitchhiker  0.0034413 
 
 
-
 
NC_007963  Csal_0102  two component heavy metal response transcriptional regulator  60.62 
 
 
223 aa  265  4e-70  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.753235  n/a   
 
 
-
 
NC_010501  PputW619_0064  two component heavy metal response transcriptional regulator  57.46 
 
 
224 aa  265  4e-70  Pseudomonas putida W619  Bacteria  normal  hitchhiker  0.000118539 
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  59.47 
 
 
225 aa  264  7e-70  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
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