More than 300 homologs were found in PanDaTox collection
for query gene Plut_1592 on replicon NC_007512
Organism: Chlorobium luteolum DSM 273



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_002939  GSU1276  carbamoyl-phosphate synthase, large subunit  53.82 
 
 
1081 aa  641    Geobacter sulfurreducens PCA  Bacteria  normal  0.104945  n/a   
 
 
-
 
NC_011059  Paes_0582  Carbamoyl-phosphate synthetase large chain domain protein  83.47 
 
 
618 aa  1064    Prosthecochloris aestuarii DSM 271  Bacteria  hitchhiker  0.000594141  normal  0.448613 
 
 
-
 
NC_007512  Plut_1592  carbamoyl-phosphate synthase, large subunit  100 
 
 
619 aa  1277    Chlorobium luteolum DSM 273  Bacteria  normal  normal  0.430094 
 
 
-
 
NC_007514  Cag_1787  carbamoyl-phosphate synthase, large subunit  85.64 
 
 
621 aa  1095    Chlorobium chlorochromatii CaD3  Bacteria  normal  n/a   
 
 
-
 
NC_010803  Clim_1967  Carbamoyl-phosphate synthetase large chain domain protein  87.52 
 
 
618 aa  1128    Chlorobium limicola DSM 245  Bacteria  hitchhiker  0.000000143423  n/a   
 
 
-
 
NC_007517  Gmet_1774  carbamoyl-phosphate synthase large subunit  54.16 
 
 
1081 aa  653    Geobacter metallireducens GS-15  Bacteria  decreased coverage  0.00000157385  normal  0.0854041 
 
 
-
 
NC_011146  Gbem_1900  carbamoyl-phosphate synthase, large subunit  54.05 
 
 
1082 aa  641    Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00662116  n/a   
 
 
-
 
NC_008009  Acid345_2197  carbamoyl-phosphate synthase large subunit  53.15 
 
 
1102 aa  643    Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_010831  Cphamn1_0628  Carbamoyl-phosphate synthetase large chain domain protein  81.36 
 
 
618 aa  1045    Chlorobium phaeobacteroides BS1  Bacteria  normal  normal 
 
 
-
 
NC_011060  Ppha_0725  Carbamoyl-phosphate synthetase large chain domain protein  87.36 
 
 
618 aa  1126    Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_2079  carbamoyl-phosphate synthase, large subunit  53.04 
 
 
1082 aa  636    Geobacter lovleyi SZ  Bacteria  normal  0.0359545  n/a   
 
 
-
 
NC_009483  Gura_1864  carbamoyl-phosphate synthase, large subunit  53.82 
 
 
1082 aa  639    Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000611023  n/a   
 
 
-
 
NC_008609  Ppro_2524  carbamoyl-phosphate synthase, large subunit  52.68 
 
 
1078 aa  642    Pelobacter propionicus DSM 2379  Bacteria  normal  0.0237548  n/a   
 
 
-
 
NC_008639  Cpha266_0599  carbamoyl-phosphate synthase large subunit  87.52 
 
 
618 aa  1124    Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_2308  carbamoyl-phosphate synthase, large subunit  53.72 
 
 
1082 aa  638    Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_008554  Sfum_0008  carbamoyl phosphate synthase large subunit  51.84 
 
 
1080 aa  633  1e-180  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.196188  normal 
 
 
-
 
NC_013223  Dret_0320  carbamoyl-phosphate synthase, large subunit  52.08 
 
 
1078 aa  631  1e-179  Desulfohalobium retbaense DSM 5692  Bacteria  unclonable  0.000000336143  normal 
 
 
-
 
NC_007498  Pcar_1612  carbamoyl-phosphate synthase large subunit  51.99 
 
 
1084 aa  619  1e-176  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.00000000225246  n/a   
 
 
-
 
NC_011769  DvMF_2306  carbamoyl-phosphate synthase, large subunit  51.18 
 
 
1078 aa  620  1e-176  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_009675  Anae109_2072  carbamoyl phosphate synthase large subunit  50.83 
 
 
1083 aa  617  1e-175  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal  0.471557 
 
 
-
 
NC_010117  COXBURSA331_A1430  carbamoyl-phosphate synthase, large subunit  50.77 
 
 
1073 aa  615  1e-175  Coxiella burnetii RSA 331  Bacteria  normal  n/a   
 
 
-
 
NC_009943  Dole_0121  carbamoyl-phosphate synthase, large subunit  53.94 
 
 
1075 aa  618  1e-175  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_007519  Dde_0333  carbamoyl-phosphate synthase large subunit  50.25 
 
 
1087 aa  612  9.999999999999999e-175  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.639877  n/a   
 
 
-
 
NC_013173  Dbac_3211  carbamoyl-phosphate synthase, large subunit  51.78 
 
 
1082 aa  613  9.999999999999999e-175  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_009727  CBUD_1370  carbamoyl-phosphate synthase large chain  50.6 
 
 
1073 aa  613  9.999999999999999e-175  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  0.636117  n/a   
 
 
-
 
NC_011831  Cagg_2456  carbamoyl-phosphate synthase, large subunit  51.94 
 
 
1096 aa  612  9.999999999999999e-175  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_009719  Plav_2313  carbamoyl-phosphate synthase, large subunit  50.89 
 
 
1079 aa  605  9.999999999999999e-173  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.417995  normal  0.014378 
 
 
-
 
NC_008576  Mmc1_3018  carbamoyl-phosphate synthase large subunit  50.59 
 
 
1074 aa  605  9.999999999999999e-173  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_5230  carbamoyl phosphate synthase large subunit  50.5 
 
 
1082 aa  604  1.0000000000000001e-171  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_007760  Adeh_1729  carbamoyl phosphate synthase large subunit  49.83 
 
 
1077 aa  605  1.0000000000000001e-171  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_2208  carbamoyl phosphate synthase large subunit  49.51 
 
 
1077 aa  602  1.0000000000000001e-171  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2806  carbamoyl-phosphate synthase, large subunit  50.34 
 
 
1077 aa  602  1.0000000000000001e-171  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_011145  AnaeK_2118  carbamoyl phosphate synthase large subunit  49.51 
 
 
1077 aa  601  1e-170  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_009511  Swit_0438  carbamoyl phosphate synthase large subunit  48.85 
 
 
1110 aa  599  1e-170  Sphingomonas wittichii RW1  Bacteria  normal  0.561352  normal 
 
 
-
 
NC_013510  Tcur_3012  carbamoyl-phosphate synthase, large subunit  50.4 
 
 
1107 aa  599  1e-170  Thermomonospora curvata DSM 43183  Bacteria  normal  0.541011  n/a   
 
 
-
 
NC_010655  Amuc_1251  carbamoyl-phosphate synthase, large subunit  51.78 
 
 
1067 aa  598  1e-169  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  normal 
 
 
-
 
NC_014248  Aazo_0571  carbamoyl-phosphate synthase large subunit  48.95 
 
 
1094 aa  597  1e-169  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_1893  carbamoyl phosphate synthase large subunit  49.52 
 
 
1097 aa  597  1e-169  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.457655 
 
 
-
 
NC_007794  Saro_2230  carbamoyl phosphate synthase large subunit  50.92 
 
 
1107 aa  597  1e-169  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.497608  n/a   
 
 
-
 
NC_013169  Ksed_12690  carbamoyl-phosphate synthase large subunit  48.97 
 
 
1118 aa  596  1e-169  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0359466  normal  0.0639836 
 
 
-
 
NC_011726  PCC8801_0628  carbamoyl phosphate synthase large subunit  51.08 
 
 
1081 aa  598  1e-169  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_0645  carbamoyl phosphate synthase large subunit  50.91 
 
 
1081 aa  596  1e-169  Cyanothece sp. PCC 8802  Bacteria  normal  normal  0.796539 
 
 
-
 
NC_002977  MCA1852  carbamoyl-phosphate synthase, large subunit  49.92 
 
 
1072 aa  594  1e-168  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_3102  carbamoyl-phosphate synthase, large subunit  49.76 
 
 
1100 aa  592  1e-168  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_1710  carbamoyl phosphate synthase large subunit  49.76 
 
 
1136 aa  593  1e-168  Frankia sp. EAN1pec  Bacteria  normal  hitchhiker  0.00485747 
 
 
-
 
NC_007777  Francci3_3198  carbamoyl phosphate synthase large subunit  49.36 
 
 
1130 aa  594  1e-168  Frankia sp. CcI3  Bacteria  decreased coverage  0.00397433  normal 
 
 
-
 
NC_010571  Oter_0679  carbamoyl-phosphate synthase, large subunit  50 
 
 
1095 aa  593  1e-168  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_009635  Maeo_0045  carbamoyl-phosphate synthase L chain ATP-binding  47.74 
 
 
604 aa  592  1e-168  Methanococcus aeolicus Nankai-3  Archaea  normal  0.308823  n/a   
 
 
-
 
NC_011312  VSAL_I0586  carbamoyl phosphate synthase large subunit  49.51 
 
 
1076 aa  589  1e-167  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.221423  n/a   
 
 
-
 
NC_013440  Hoch_4206  carbamoyl-phosphate synthase, large subunit  52.27 
 
 
1077 aa  590  1e-167  Haliangium ochraceum DSM 14365  Bacteria  normal  0.412079  normal 
 
 
-
 
NC_009523  RoseRS_4057  carbamoyl-phosphate synthase, large subunit  49.84 
 
 
1113 aa  589  1e-167  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_008340  Mlg_1981  carbamoyl-phosphate synthase large subunit  50.43 
 
 
1078 aa  588  1e-167  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  decreased coverage  0.00635498 
 
 
-
 
NC_009664  Krad_3001  carbamoyl-phosphate synthase, large subunit  49.92 
 
 
1104 aa  587  1e-166  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.105986  normal  0.458872 
 
 
-
 
NC_011886  Achl_1999  carbamoyl phosphate synthase large subunit  49.43 
 
 
1109 aa  587  1e-166  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.0000000570089 
 
 
-
 
NC_009975  MmarC6_1646  carbamoyl-phosphate synthase, large subunit  49.25 
 
 
1081 aa  585  1e-166  Methanococcus maripaludis C6  Archaea  normal  n/a   
 
 
-
 
NC_007333  Tfu_1057  carbamoyl-phosphate synthase large subunit  49.6 
 
 
1103 aa  585  1e-166  Thermobifida fusca YX  Bacteria  normal  0.614826  n/a   
 
 
-
 
NC_009767  Rcas_3357  carbamoyl-phosphate synthase, large subunit  49.27 
 
 
1112 aa  588  1e-166  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_007484  Noc_2572  carbamoyl-phosphate synthase, large subunit, glutamine-dependent  50.78 
 
 
1073 aa  588  1e-166  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.0164695  n/a   
 
 
-
 
NC_009972  Haur_0060  carbamoyl-phosphate synthase, large subunit  48.74 
 
 
1065 aa  585  1e-166  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_0711  carbamoyl phosphate synthase large subunit  49.84 
 
 
1097 aa  585  1e-166  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_009634  Mevan_0341  carbamoyl-phosphate synthase, large subunit  48.37 
 
 
1081 aa  587  1e-166  Methanococcus vannielii SB  Archaea  normal  0.756805  n/a   
 
 
-
 
NC_008044  TM1040_0632  carbamoyl phosphate synthase large subunit  49.35 
 
 
1120 aa  586  1e-166  Ruegeria sp. TM1040  Bacteria  normal  0.298922  normal  0.175677 
 
 
-
 
NC_008254  Meso_2095  carbamoyl phosphate synthase large subunit  47.45 
 
 
1162 aa  587  1e-166  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_009135  MmarC5_0581  carbamoyl-phosphate synthase large subunit  49.41 
 
 
1081 aa  587  1e-166  Methanococcus maripaludis C5  Archaea  normal  0.600476  n/a   
 
 
-
 
NC_013131  Caci_2405  carbamoyl-phosphate synthase, large subunit  49.19 
 
 
1099 aa  588  1e-166  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_1321  carbamoyl-phosphate synthase, large subunit  50.64 
 
 
1109 aa  587  1e-166  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.149141 
 
 
-
 
NC_013521  Sked_18000  carbamoyl-phosphate synthase large subunit  49.68 
 
 
1107 aa  586  1e-166  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.77035  normal 
 
 
-
 
NC_011365  Gdia_3031  carbamoyl phosphate synthase large subunit  49.52 
 
 
1084 aa  582  1.0000000000000001e-165  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  0.144026  decreased coverage  0.0049366 
 
 
-
 
NC_007520  Tcr_0879  carbamoyl-phosphate synthase, large subunit  49.23 
 
 
1070 aa  582  1.0000000000000001e-165  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_1088  carbamoyl-phosphate synthase, large subunit  49.68 
 
 
1157 aa  582  1.0000000000000001e-165  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.464939 
 
 
-
 
NC_009637  MmarC7_0255  carbamoyl-phosphate synthase, large subunit  48.69 
 
 
1081 aa  583  1.0000000000000001e-165  Methanococcus maripaludis C7  Archaea  normal  0.527098  normal  0.0694111 
 
 
-
 
NC_008048  Sala_0985  carbamoyl phosphate synthase large subunit  48.15 
 
 
1106 aa  582  1.0000000000000001e-165  Sphingopyxis alaskensis RB2256  Bacteria  normal  0.557617  normal 
 
 
-
 
NC_011757  Mchl_1217  carbamoyl-phosphate synthase, large subunit  49.68 
 
 
1157 aa  582  1.0000000000000001e-165  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_008789  Hhal_1775  carbamoyl-phosphate synthase, large subunit  49.14 
 
 
1073 aa  582  1.0000000000000001e-165  Halorhodospira halophila SL1  Bacteria  normal  0.0103005  n/a   
 
 
-
 
NC_008686  Pden_1879  carbamoyl phosphate synthase large subunit  49.21 
 
 
1110 aa  582  1.0000000000000001e-165  Paracoccus denitrificans PD1222  Bacteria  normal  normal  0.99136 
 
 
-
 
NC_009720  Xaut_2750  carbamoyl-phosphate synthase, large subunit  48.11 
 
 
1120 aa  580  1e-164  Xanthobacter autotrophicus Py2  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_11413  carbamoyl phosphate synthase large subunit  49.36 
 
 
1115 aa  581  1e-164  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.00750159  normal  0.0530566 
 
 
-
 
NC_013889  TK90_0699  carbamoyl-phosphate synthase, large subunit  49.83 
 
 
1077 aa  582  1e-164  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.133334  normal  0.0796001 
 
 
-
 
NC_009338  Mflv_3743  carbamoyl phosphate synthase large subunit  49.28 
 
 
1112 aa  580  1e-164  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal  0.0558638 
 
 
-
 
NC_010725  Mpop_1022  carbamoyl-phosphate synthase, large subunit  49.68 
 
 
1157 aa  579  1e-164  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_013203  Apar_0613  carbamoyl-phosphate synthase, large subunit  48.07 
 
 
1073 aa  579  1e-164  Atopobium parvulum DSM 20469  Bacteria  normal  0.438109  normal  0.344128 
 
 
-
 
NC_011901  Tgr7_0977  carbamoyl-phosphate synthase, large subunit  50.7 
 
 
1072 aa  580  1e-164  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  0.270817  n/a   
 
 
-
 
NC_012803  Mlut_12580  carbamoyl phosphate synthase large subunit  49.5 
 
 
1101 aa  579  1e-164  Micrococcus luteus NCTC 2665  Bacteria  normal  0.0991038  n/a   
 
 
-
 
NC_009428  Rsph17025_0361  carbamoyl phosphate synthase large subunit  49.36 
 
 
1109 aa  578  1.0000000000000001e-163  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  0.175688  normal  0.763709 
 
 
-
 
NC_009654  Mmwyl1_4034  carbamoyl-phosphate synthase, large subunit  48.68 
 
 
1071 aa  577  1.0000000000000001e-163  Marinomonas sp. MWYL1  Bacteria  hitchhiker  0.00188727  normal 
 
 
-
 
NC_009457  VC0395_A1967  carbamoyl phosphate synthase large subunit  48.85 
 
 
1076 aa  578  1.0000000000000001e-163  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_013235  Namu_4275  carbamoyl-phosphate synthase, large subunit  48.95 
 
 
1124 aa  577  1.0000000000000001e-163  Nakamurella multipartita DSM 44233  Bacteria  normal  0.40687  normal 
 
 
-
 
NC_009485  BBta_6799  carbamoyl phosphate synthase large subunit  48.87 
 
 
1154 aa  575  1.0000000000000001e-163  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.896081 
 
 
-
 
NC_013595  Sros_2808  carbamoyl-phosphate synthase, large subunit  49.52 
 
 
1097 aa  576  1.0000000000000001e-163  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_014148  Plim_0334  carbamoyl-phosphate synthase, large subunit  49.25 
 
 
1090 aa  576  1.0000000000000001e-163  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_013204  Elen_1670  carbamoyl-phosphate synthase, large subunit  48.92 
 
 
1078 aa  577  1.0000000000000001e-163  Eggerthella lenta DSM 2243  Bacteria  normal  hitchhiker  0.00809225 
 
 
-
 
NC_010717  PXO_00086  carbamoyl phosphate synthase large subunit  49.4 
 
 
1080 aa  575  1.0000000000000001e-163  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_2340  carbamoyl-phosphate synthase, large subunit  49.68 
 
 
1110 aa  578  1.0000000000000001e-163  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_4605  carbamoyl phosphate synthase large subunit  48.48 
 
 
1109 aa  576  1.0000000000000001e-163  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.709642  n/a   
 
 
-
 
NC_008345  Sfri_0976  carbamoyl phosphate synthase large subunit  48.51 
 
 
1073 aa  576  1.0000000000000001e-163  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_2262  carbamoyl phosphate synthase large subunit  49.43 
 
 
1099 aa  578  1.0000000000000001e-163  Arthrobacter sp. FB24  Bacteria  normal  0.133094  n/a   
 
 
-
 
NC_011071  Smal_1812  carbamoyl phosphate synthase large subunit  48.92 
 
 
1080 aa  577  1.0000000000000001e-163  Stenotrophomonas maltophilia R551-3  Bacteria  decreased coverage  0.00557421  normal  0.0258544 
 
 
-
 
NC_008554  Sfum_3911  carbamoyl phosphate synthase large subunit  48.67 
 
 
1066 aa  575  1.0000000000000001e-163  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.123492 
 
 
-
 
NC_011138  MADE_02243  carbamoyl phosphate synthase large subunit  49.07 
 
 
1073 aa  577  1.0000000000000001e-163  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_008578  Acel_1298  carbamoyl-phosphate synthase large subunit  49.27 
 
 
1093 aa  575  1.0000000000000001e-163  Acidothermus cellulolyticus 11B  Bacteria  normal  normal  0.0243124 
 
 
-
 
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