More than 300 homologs were found in PanDaTox collection
for query gene Jden_1197 on replicon NC_013174
Organism: Jonesia denitrificans DSM 20603



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013174  Jden_1197  HAD-superfamily hydrolase, subfamily IA, variant 3  100 
 
 
225 aa  457  9.999999999999999e-129  Jonesia denitrificans DSM 20603  Bacteria  normal  0.0955551  normal  0.148864 
 
 
-
 
NC_013521  Sked_20940  haloacid dehalogenase superfamily enzyme, subfamily IA  51.61 
 
 
273 aa  235  5.0000000000000005e-61  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.650807 
 
 
-
 
NC_013530  Xcel_1481  HAD-superfamily hydrolase, subfamily IA, variant 3  49.54 
 
 
233 aa  209  2e-53  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_2245  HAD-superfamily hydrolase, subfamily IA, variant 3  49.33 
 
 
247 aa  206  3e-52  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.56873  normal 
 
 
-
 
NC_008699  Noca_2632  HAD family hydrolase  46.31 
 
 
218 aa  189  4e-47  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_014151  Cfla_2008  HAD-superfamily hydrolase, subfamily IA, variant 3  45.58 
 
 
213 aa  187  1e-46  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.296794  normal 
 
 
-
 
NC_013169  Ksed_13910  haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED  48.04 
 
 
232 aa  181  9.000000000000001e-45  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.491881  normal 
 
 
-
 
NC_009664  Krad_1843  HAD-superfamily hydrolase, subfamily IA, variant 3  43.69 
 
 
241 aa  169  3e-41  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.101722  normal 
 
 
-
 
NC_011886  Achl_1913  HAD-superfamily hydrolase, subfamily IA, variant 3  43.43 
 
 
245 aa  168  7e-41  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00000000014808 
 
 
-
 
NC_012803  Mlut_11830  haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED  43.81 
 
 
246 aa  166  2e-40  Micrococcus luteus NCTC 2665  Bacteria  normal  0.0867005  n/a   
 
 
-
 
NC_008541  Arth_2170  HAD family hydrolase  44.64 
 
 
263 aa  149  4e-35  Arthrobacter sp. FB24  Bacteria  normal  0.156461  n/a   
 
 
-
 
NC_013595  Sros_5916  HAD family hydrolase  38.83 
 
 
218 aa  144  8.000000000000001e-34  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0345843  normal  0.0351614 
 
 
-
 
NC_014165  Tbis_1853  HAD-superfamily hydrolase  36.55 
 
 
213 aa  131  6.999999999999999e-30  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_013721  HMPREF0424_1278  HAD hydrolase, family IA, variant 3  33.03 
 
 
247 aa  131  7.999999999999999e-30  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_014210  Ndas_1550  HAD-superfamily hydrolase, subfamily IA, variant 3  38.46 
 
 
249 aa  126  2.0000000000000002e-28  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal  0.204001 
 
 
-
 
NC_013093  Amir_2212  HAD-superfamily hydrolase, subfamily IA, variant 3  36.22 
 
 
220 aa  123  2e-27  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013159  Svir_22200  haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED  36.6 
 
 
217 aa  123  3e-27  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.172111  normal 
 
 
-
 
NC_008578  Acel_1175  HAD family hydrolase  36.89 
 
 
263 aa  121  9e-27  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_4498  HAD-superfamily hydrolase subfamily IA, variant 3  36.14 
 
 
223 aa  121  9.999999999999999e-27  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.511661  normal  0.0143777 
 
 
-
 
NC_007333  Tfu_1824  HAD family hydrolase  38.92 
 
 
222 aa  118  7e-26  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_2412  HAD-superfamily hydrolase, subfamily IA, variant 3  32.69 
 
 
222 aa  113  2.0000000000000002e-24  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_3473  HAD family hydrolase  34.47 
 
 
243 aa  113  2.0000000000000002e-24  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_009380  Strop_2232  HAD family hydrolase  39.9 
 
 
233 aa  109  4.0000000000000004e-23  Salinispora tropica CNB-440  Bacteria  normal  0.470588  normal 
 
 
-
 
NC_013510  Tcur_2293  HAD-superfamily hydrolase, subfamily IA, variant 3  35.91 
 
 
218 aa  107  2e-22  Thermomonospora curvata DSM 43183  Bacteria  hitchhiker  0.0000494788  n/a   
 
 
-
 
NC_009953  Sare_2349  HAD family hydrolase  38.83 
 
 
215 aa  106  2e-22  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.355354 
 
 
-
 
NC_010816  BLD_1305  beta-phosphoglucomutase  34.62 
 
 
223 aa  105  5e-22  Bifidobacterium longum DJO10A  Bacteria  normal  0.396501  n/a   
 
 
-
 
NC_009338  Mflv_3054  HAD family hydrolase  32.21 
 
 
224 aa  105  8e-22  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.751068  normal  0.223571 
 
 
-
 
NC_013441  Gbro_2452  HAD-superfamily hydrolase, subfamily IA, variant 3  40.41 
 
 
232 aa  102  4e-21  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_009953  Sare_4356  HAD family hydrolase  32.27 
 
 
233 aa  101  9e-21  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.582602 
 
 
-
 
NC_008146  Mmcs_3148  HAD family hydrolase  36.67 
 
 
228 aa  98.2  9e-20  Mycobacterium sp. MCS  Bacteria  normal  0.0274068  n/a   
 
 
-
 
NC_008705  Mkms_3210  HAD family hydrolase  36.67 
 
 
228 aa  98.2  9e-20  Mycobacterium sp. KMS  Bacteria  normal  0.742759  normal  0.278604 
 
 
-
 
NC_009077  Mjls_3160  HAD family hydrolase  36.67 
 
 
228 aa  98.2  9e-20  Mycobacterium sp. JLS  Bacteria  normal  0.0720917  normal  0.533727 
 
 
-
 
NC_009380  Strop_3972  HAD family hydrolase  30.59 
 
 
241 aa  95.5  5e-19  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_7029  HAD-superfamily hydrolase, subfamily IA, variant 3  32.6 
 
 
213 aa  94.7  1e-18  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_014158  Tpau_2146  HAD-superfamily hydrolase, subfamily IA, variant 3  32.32 
 
 
213 aa  94.4  1e-18  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_2637  HAD family hydrolase  33.33 
 
 
286 aa  94  2e-18  Frankia sp. CcI3  Bacteria  normal  0.403398  normal  0.292856 
 
 
-
 
NC_013595  Sros_7385  HAD-superfamily hydrolase, subfamily IA  30.42 
 
 
248 aa  93.6  2e-18  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_007955  Mbur_1556  HAD family hydrolase  30.15 
 
 
232 aa  93.2  3e-18  Methanococcoides burtonii DSM 6242  Archaea  decreased coverage  0.0000000000353855  n/a   
 
 
-
 
NC_009092  Shew_3425  2-deoxyglucose-6-phosphatase  30.05 
 
 
223 aa  92.4  6e-18  Shewanella loihica PV-4  Bacteria  hitchhiker  0.000919178  normal 
 
 
-
 
NC_008321  Shewmr4_0436  2-deoxyglucose-6-phosphatase  30.81 
 
 
218 aa  91.7  8e-18  Shewanella sp. MR-4  Bacteria  unclonable  0.0000000024214  normal 
 
 
-
 
NC_004347  SO_0431  2-deoxyglucose-6-phosphatase  31.35 
 
 
217 aa  91.3  1e-17  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009972  Haur_4152  HAD family hydrolase  30.69 
 
 
217 aa  91.3  1e-17  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2485  HAD-superfamily hydrolase, subfamily IA, variant 3  31.22 
 
 
238 aa  91.3  1e-17  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_3410  2-deoxyglucose-6-phosphatase  30.65 
 
 
217 aa  90.1  2e-17  Shewanella putrefaciens CN-32  Bacteria  normal  0.0110715  n/a   
 
 
-
 
NC_007335  PMN2A_0056  HAD family hydrolase  30.43 
 
 
226 aa  89.7  3e-17  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_008819  NATL1_06771  phosphatase/phosphohexomutase  32.05 
 
 
226 aa  89.4  4e-17  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3593  2-deoxyglucose-6-phosphatase  30.27 
 
 
218 aa  89  5e-17  Shewanella sp. MR-7  Bacteria  unclonable  0.0000011766  normal  0.672534 
 
 
-
 
NC_008577  Shewana3_0432  2-deoxyglucose-6-phosphatase  30.81 
 
 
218 aa  89  5e-17  Shewanella sp. ANA-3  Bacteria  unclonable  0.00000000498152  normal 
 
 
-
 
NC_013235  Namu_2787  HAD-superfamily hydrolase, subfamily IA, variant 3  29.32 
 
 
230 aa  87.8  1e-16  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.00137861  hitchhiker  0.0000132599 
 
 
-
 
NC_013159  Svir_39300  haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED  30.73 
 
 
218 aa  87  2e-16  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_5789  HAD-superfamily hydrolase subfamily IA, variant 3  31.16 
 
 
248 aa  86.7  3e-16  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.805096 
 
 
-
 
NC_007778  RPB_1286  HAD family hydrolase  30.98 
 
 
229 aa  86.3  4e-16  Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_4889  HAD family hydrolase  32.35 
 
 
233 aa  85.9  4e-16  Frankia sp. EAN1pec  Bacteria  normal  0.351284  normal  0.0730929 
 
 
-
 
NC_009831  Ssed_0437  2-deoxyglucose-6-phosphatase  29.35 
 
 
221 aa  85.1  7e-16  Shewanella sediminis HAW-EB3  Bacteria  hitchhiker  0.000647119  hitchhiker  0.00000756317 
 
 
-
 
NC_013757  Gobs_2673  HAD-superfamily hydrolase, subfamily IA, variant 3  34.3 
 
 
248 aa  85.1  8e-16  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.649761  n/a   
 
 
-
 
NC_007355  Mbar_A0742  beta-phosphoglucomutase  29.85 
 
 
214 aa  84.3  0.000000000000001  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_011071  Smal_0452  HAD-superfamily hydrolase, subfamily IA, variant 3  34.72 
 
 
227 aa  84.7  0.000000000000001  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal 
 
 
-
 
NC_011094  SeSA_A1419  2-deoxyglucose-6-phosphatase  32 
 
 
222 aa  84.3  0.000000000000001  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.744627  hitchhiker  0.00259415 
 
 
-
 
NC_009654  Mmwyl1_0641  HAD family hydrolase  31.15 
 
 
220 aa  84.3  0.000000000000001  Marinomonas sp. MWYL1  Bacteria  normal  0.950078  normal  0.0427696 
 
 
-
 
NC_010513  Xfasm12_0542  hydrolase  32.97 
 
 
225 aa  83.6  0.000000000000002  Xylella fastidiosa M12  Bacteria  normal  0.491879  n/a   
 
 
-
 
NC_009901  Spea_0424  2-deoxyglucose-6-phosphatase  28.78 
 
 
222 aa  84  0.000000000000002  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_1912  2-deoxyglucose-6-phosphatase  30.45 
 
 
223 aa  83.6  0.000000000000002  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.0120822  n/a   
 
 
-
 
NC_013205  Aaci_2469  HAD-superfamily hydrolase, subfamily IA, variant 3  30.69 
 
 
224 aa  83.6  0.000000000000002  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.618161  n/a   
 
 
-
 
NC_008345  Sfri_3772  2-deoxyglucose-6-phosphatase  29.74 
 
 
218 aa  83.2  0.000000000000003  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008700  Sama_0381  2-deoxyglucose-6-phosphatase  31.16 
 
 
221 aa  83.2  0.000000000000003  Shewanella amazonensis SB2B  Bacteria  hitchhiker  0.0071153  normal  0.324571 
 
 
-
 
NC_011205  SeD_A2022  2-deoxyglucose-6-phosphatase  31.5 
 
 
222 aa  82.8  0.000000000000004  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal 
 
 
-
 
NC_011004  Rpal_4817  HAD-superfamily hydrolase, subfamily IA, variant 3  30.6 
 
 
235 aa  82.4  0.000000000000004  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.821962  n/a   
 
 
-
 
NC_011149  SeAg_B1849  2-deoxyglucose-6-phosphatase  31.5 
 
 
222 aa  82.8  0.000000000000004  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  hitchhiker  0.0029739  n/a   
 
 
-
 
NC_013173  Dbac_1634  HAD-superfamily hydrolase, subfamily IA, variant 3  33.17 
 
 
221 aa  82.8  0.000000000000004  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.0501975  n/a   
 
 
-
 
NC_008709  Ping_3528  HAD family hydrolase  29.11 
 
 
222 aa  82.8  0.000000000000004  Psychromonas ingrahamii 37  Bacteria  normal  0.894258  hitchhiker  0.00350401 
 
 
-
 
NC_011080  SNSL254_A1436  2-deoxyglucose-6-phosphatase  31.5 
 
 
222 aa  82.8  0.000000000000004  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  0.905236  normal 
 
 
-
 
NC_008817  P9515_15581  phosphatase/phosphohexomutase  29.41 
 
 
225 aa  82.8  0.000000000000004  Prochlorococcus marinus str. MIT 9515  Bacteria  normal  n/a   
 
 
-
 
NC_011083  SeHA_C1451  2-deoxyglucose-6-phosphatase  31.5 
 
 
222 aa  82.8  0.000000000000004  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  0.913842  normal 
 
 
-
 
NC_013457  VEA_000391  2-deoxyglucose-6-phosphate hydrolase YniC  29.67 
 
 
218 aa  82  0.000000000000006  Vibrio sp. Ex25  Bacteria  normal  0.0106831  n/a   
 
 
-
 
NC_010577  XfasM23_0479  HAD family hydrolase  32.04 
 
 
225 aa  82  0.000000000000006  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_1853  HAD family hydrolase  30.16 
 
 
235 aa  82  0.000000000000007  Frankia sp. EAN1pec  Bacteria  normal  0.147437  normal  0.0157174 
 
 
-
 
NC_009997  Sbal195_4047  2-deoxyglucose-6-phosphatase  30.81 
 
 
219 aa  81.6  0.000000000000008  Shewanella baltica OS195  Bacteria  hitchhiker  0.0000965281  normal  0.234971 
 
 
-
 
NC_011661  Dtur_0461  HAD-superfamily hydrolase, subfamily IA, variant 3  24.87 
 
 
217 aa  81.6  0.000000000000009  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_009456  VC0395_0037  haloacid dehalogenase/epoxide hydrolase family protein  28.9 
 
 
219 aa  81.6  0.000000000000009  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_009665  Shew185_3926  2-deoxyglucose-6-phosphatase  30.81 
 
 
219 aa  81.3  0.00000000000001  Shewanella baltica OS185  Bacteria  hitchhiker  0.00000000238408  n/a   
 
 
-
 
NC_011059  Paes_0473  HAD-superfamily hydrolase, subfamily IA, variant 3  30.77 
 
 
211 aa  81.3  0.00000000000001  Prosthecochloris aestuarii DSM 271  Bacteria  hitchhiker  0.0000148872  normal 
 
 
-
 
NC_007413  Ava_3074  HAD family hydrolase  30 
 
 
222 aa  80.9  0.00000000000001  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_009784  VIBHAR_05174  phosphoglycolate phosphatase  30.05 
 
 
256 aa  80.9  0.00000000000001  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_002977  MCA2733  HAD-superfamily hydrolase, subfamily IA, variant 3 family protein  32.84 
 
 
237 aa  80.1  0.00000000000002  Methylococcus capsulatus str. Bath  Bacteria  normal  0.53567  n/a   
 
 
-
 
NC_010506  Swoo_0284  2-deoxyglucose-6-phosphatase  28.65 
 
 
221 aa  80.5  0.00000000000002  Shewanella woodyi ATCC 51908  Bacteria  normal  hitchhiker  0.00458991 
 
 
-
 
NC_010465  YPK_1808  2-deoxyglucose-6-phosphatase  30.48 
 
 
221 aa  80.9  0.00000000000002  Yersinia pseudotuberculosis YPIII  Bacteria  normal  0.417032  n/a   
 
 
-
 
NC_008148  Rxyl_0905  HAD family hydrolase  31.43 
 
 
204 aa  80.5  0.00000000000002  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.427836  n/a   
 
 
-
 
NC_009708  YpsIP31758_1697  2-deoxyglucose-6-phosphatase  30.48 
 
 
221 aa  80.9  0.00000000000002  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_010338  Caul_0320  HAD family hydrolase  31.91 
 
 
241 aa  80.1  0.00000000000002  Caulobacter sp. K31  Bacteria  normal  0.288784  normal 
 
 
-
 
NC_010717  PXO_03084  HAD superfamily hydrolase  31.02 
 
 
226 aa  80.9  0.00000000000002  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_010084  Bmul_0864  HAD family hydrolase  31.02 
 
 
226 aa  80.1  0.00000000000003  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_0780  HAD family hydrolase  29.08 
 
 
227 aa  79.3  0.00000000000004  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_009052  Sbal_3906  2-deoxyglucose-6-phosphatase  30.3 
 
 
219 aa  79.3  0.00000000000004  Shewanella baltica OS155  Bacteria  unclonable  0.000000000443869  n/a   
 
 
-
 
CP001509  ECD_01696  predicted hydrolase  29.33 
 
 
222 aa  79  0.00000000000005  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_1905  2-deoxyglucose-6-phosphatase  29.33 
 
 
222 aa  79  0.00000000000005  Escherichia coli ATCC 8739  Bacteria  normal  0.798501  normal  0.727123 
 
 
-
 
CP001637  EcDH1_1915  HAD-superfamily hydrolase, subfamily IA, variant 3  29.33 
 
 
222 aa  79  0.00000000000005  Escherichia coli DH1  Bacteria  normal  0.752357  n/a   
 
 
-
 
NC_009436  Ent638_1717  2-deoxyglucose-6-phosphatase  29.23 
 
 
223 aa  79  0.00000000000005  Enterobacter sp. 638  Bacteria  normal  normal  0.886251 
 
 
-
 
NC_009800  EcHS_A1808  2-deoxyglucose-6-phosphatase  29.33 
 
 
222 aa  79  0.00000000000005  Escherichia coli HS  Bacteria  normal  0.305682  n/a   
 
 
-
 
NC_012892  B21_01684  hypothetical protein  29.33 
 
 
222 aa  79  0.00000000000005  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_1947  2-deoxyglucose-6-phosphatase  29.33 
 
 
222 aa  79  0.00000000000006  Escherichia coli E24377A  Bacteria  normal  0.504113  n/a   
 
 
-
 
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