More than 300 homologs were found in PanDaTox collection
for query gene TDE2659 on replicon NC_002967
Organism: Treponema denticola ATCC 35405



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_002967  TDE2659  GAF domain/HD domain-containing protein  100 
 
 
417 aa  857    Treponema denticola ATCC 35405  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_3061  metal dependent phosphohydrolase  49.74 
 
 
419 aa  396  1e-109  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011146  Gbem_1212  metal dependent phosphohydrolase  48.97 
 
 
418 aa  385  1e-106  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00677868  n/a   
 
 
-
 
NC_010814  Glov_2677  metal dependent phosphohydrolase  49.11 
 
 
415 aa  384  1e-105  Geobacter lovleyi SZ  Bacteria  normal  0.508126  n/a   
 
 
-
 
NC_010644  Emin_0051  metal dependent phosphohydrolase  32.93 
 
 
407 aa  182  9.000000000000001e-45  Elusimicrobium minutum Pei191  Bacteria  normal  normal 
 
 
-
 
NC_009718  Fnod_1705  response regulator receiver modulated metal dependent phosphohydrolase  38.06 
 
 
471 aa  173  5.999999999999999e-42  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
NC_007954  Sden_3723  response regulator receiver  40.74 
 
 
338 aa  164  3e-39  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_008577  Shewana3_3334  response regulator receiver modulated metal dependent phosphohydrolase  42.79 
 
 
331 aa  164  3e-39  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_008321  Shewmr4_0792  response regulator receiver modulated metal dependent phosphohydrolase  42.33 
 
 
331 aa  163  5.0000000000000005e-39  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3231  response regulator receiver modulated metal dependent phosphohydrolase  42.33 
 
 
331 aa  163  5.0000000000000005e-39  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008010  Dgeo_2833  metal dependent phosphohydrolase  44.29 
 
 
379 aa  161  2e-38  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.0209293  n/a   
 
 
-
 
NC_008700  Sama_3111  response regulator receiver protein  39.82 
 
 
328 aa  161  2e-38  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.0637882 
 
 
-
 
NC_011138  MADE_01756  Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase)  40.99 
 
 
337 aa  160  6e-38  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.844049  n/a   
 
 
-
 
NC_013216  Dtox_4196  response regulator receiver modulated metal dependent phosphohydrolase  39.53 
 
 
350 aa  159  8e-38  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_008228  Patl_2248  response regulator receiver modulated metal dependent phosphohydrolase  40.72 
 
 
331 aa  157  2e-37  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_1086  response regulator receiver modulated metal dependent phosphohydrolase  38.18 
 
 
331 aa  157  3e-37  Marinomonas sp. MWYL1  Bacteria  normal  0.226857  hitchhiker  0.0000000112469 
 
 
-
 
NC_008321  Shewmr4_0481  response regulator receiver modulated metal dependent phosphohydrolase  38.18 
 
 
348 aa  157  5.0000000000000005e-37  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_013552  DhcVS_1406  response regulator  42.4 
 
 
351 aa  156  6e-37  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_3141  response regulator receiver modulated metal dependent phosphohydrolase  39.07 
 
 
338 aa  156  6e-37  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_008322  Shewmr7_3549  response regulator receiver modulated metal dependent phosphohydrolase  39.09 
 
 
348 aa  156  6e-37  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_009456  VC0395_1019  putative response regulator  36.92 
 
 
522 aa  155  1e-36  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_1183  response regulator receiver modulated metal dependent phosphohydrolase  36.77 
 
 
363 aa  155  1e-36  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2138  metal dependent phosphohydrolase  42.72 
 
 
606 aa  155  1e-36  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.258694  n/a   
 
 
-
 
NC_009616  Tmel_0497  response regulator receiver modulated metal dependent phosphohydrolase  42.93 
 
 
432 aa  155  1e-36  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_2505  response regulator receiver modulated metal dependent phosphohydrolase  40 
 
 
331 aa  155  1e-36  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008740  Maqu_3676  response regulator receiver modulated metal dependent phosphohydrolase  40.28 
 
 
328 aa  155  1e-36  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_6015  response regulator receiver modulated metal dependent phosphohydrolase  38.18 
 
 
333 aa  155  1e-36  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_3313  response regulator receiver modulated metal dependent phosphohydrolase  40.28 
 
 
343 aa  154  2e-36  Shewanella woodyi ATCC 51908  Bacteria  normal  hitchhiker  0.00000482447 
 
 
-
 
NC_008576  Mmc1_3165  response regulator receiver modulated metal dependent phosphohydrolase  38.91 
 
 
367 aa  155  2e-36  Magnetococcus sp. MC-1  Bacteria  normal  0.0569095  normal  0.0154692 
 
 
-
 
NC_012560  Avin_25160  response regulator  38.39 
 
 
356 aa  154  2.9999999999999998e-36  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0492  response regulator receiver modulated metal dependent phosphohydrolase  36.02 
 
 
508 aa  153  5e-36  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.0844408  n/a   
 
 
-
 
NC_007520  Tcr_1911  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  40.87 
 
 
268 aa  152  8e-36  Thiomicrospira crunogena XCL-2  Bacteria  normal  0.0445959  n/a   
 
 
-
 
NC_011894  Mnod_5340  response regulator receiver modulated metal dependent phosphohydrolase  38.67 
 
 
348 aa  152  1e-35  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.64097  n/a   
 
 
-
 
NC_008577  Shewana3_3418  response regulator receiver modulated metal dependent phosphohydrolase  37.67 
 
 
338 aa  152  1e-35  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_2978  response regulator receiver modulated metal dependent phosphohydrolase  39.83 
 
 
369 aa  151  2e-35  Shewanella woodyi ATCC 51908  Bacteria  normal  normal  0.806511 
 
 
-
 
NC_007404  Tbd_2670  metal dependent phosphohydrolase, HD region  38.29 
 
 
344 aa  151  2e-35  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_3408  response regulator receiver modulated metal dependent phosphohydrolase  39.35 
 
 
346 aa  151  2e-35  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_011138  MADE_03429  two-component system response regulator (hybrid family) protein  37.91 
 
 
358 aa  151  2e-35  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_009035  Sbal_4485  hypothetical protein  36.48 
 
 
523 aa  151  2e-35  Shewanella baltica OS155  Bacteria  n/a    n/a   
 
 
-
 
NC_009052  Sbal_2199  response regulator receiver modulated metal dependent phosphohydrolase  36.48 
 
 
523 aa  151  2e-35  Shewanella baltica OS155  Bacteria  normal  0.179718  n/a   
 
 
-
 
NC_009253  Dred_3089  metal dependent phosphohydrolase  29.44 
 
 
366 aa  150  3e-35  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_0860  response regulator  38.14 
 
 
339 aa  150  3e-35  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008321  Shewmr4_0716  response regulator receiver modulated metal dependent phosphohydrolase  37.67 
 
 
338 aa  150  4e-35  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3306  response regulator receiver modulated metal dependent phosphohydrolase  37.67 
 
 
338 aa  150  4e-35  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_2951  response regulator receiver protein  38.14 
 
 
340 aa  150  4e-35  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.129077 
 
 
-
 
NC_011663  Sbal223_2212  response regulator receiver modulated metal dependent phosphohydrolase  36.48 
 
 
523 aa  150  5e-35  Shewanella baltica OS223  Bacteria  normal  0.16257  normal  0.683218 
 
 
-
 
NC_009997  Sbal195_0871  response regulator receiver modulated metal dependent phosphohydrolase  38.14 
 
 
338 aa  150  5e-35  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_009052  Sbal_3504  response regulator receiver modulated metal dependent phosphohydrolase  38.14 
 
 
338 aa  150  6e-35  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_0859  response regulator receiver modulated metal dependent phosphohydrolase  38.14 
 
 
338 aa  150  6e-35  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_013173  Dbac_2017  response regulator receiver modulated metal dependent phosphohydrolase  39.27 
 
 
379 aa  150  6e-35  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.98115  n/a   
 
 
-
 
NC_009665  Shew185_2172  response regulator receiver modulated metal dependent phosphohydrolase  36.82 
 
 
523 aa  150  6e-35  Shewanella baltica OS185  Bacteria  normal  0.0465103  n/a   
 
 
-
 
NC_009997  Sbal195_2222  response regulator receiver modulated metal dependent phosphohydrolase  36.82 
 
 
523 aa  150  6e-35  Shewanella baltica OS195  Bacteria  normal  0.151758  normal  0.307874 
 
 
-
 
NC_010725  Mpop_3894  response regulator receiver modulated metal dependent phosphohydrolase  38.07 
 
 
353 aa  150  6e-35  Methylobacterium populi BJ001  Bacteria  normal  0.0109719  normal  0.416002 
 
 
-
 
NC_008321  Shewmr4_2004  response regulator receiver modulated metal dependent phosphohydrolase  36.4 
 
 
525 aa  150  6e-35  Shewanella sp. MR-4  Bacteria  normal  0.0562345  hitchhiker  0.000000282251 
 
 
-
 
NC_008322  Shewmr7_1971  response regulator receiver modulated metal dependent phosphohydrolase  36.4 
 
 
525 aa  150  6e-35  Shewanella sp. MR-7  Bacteria  normal  0.0825869  normal  0.0109864 
 
 
-
 
NC_010725  Mpop_4963  response regulator receiver modulated metal dependent phosphohydrolase  40.28 
 
 
350 aa  149  7e-35  Methylobacterium populi BJ001  Bacteria  normal  0.102256  normal  0.0892849 
 
 
-
 
NC_009665  Shew185_0836  response regulator receiver modulated metal dependent phosphohydrolase  38.14 
 
 
338 aa  149  7e-35  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2902  response regulator receiver  39.46 
 
 
350 aa  149  8e-35  Dechloromonas aromatica RCB  Bacteria  normal  0.1984  normal  0.246098 
 
 
-
 
NC_007954  Sden_1853  metal-dependent phosphohydrolase  36.07 
 
 
527 aa  149  1.0000000000000001e-34  Shewanella denitrificans OS217  Bacteria  normal  0.0219327  n/a   
 
 
-
 
NC_013946  Mrub_1382  diguanylate cyclase and serine/threonine protein kinase with TPR repeats  40.85 
 
 
868 aa  148  2.0000000000000003e-34  Meiothermus ruber DSM 1279  Bacteria  normal  0.0126588  normal  0.259783 
 
 
-
 
NC_009092  Shew_3199  response regulator receiver modulated metal dependent phosphohydrolase  40 
 
 
339 aa  148  2.0000000000000003e-34  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_007519  Dde_3114  metal dependent phosphohydrolase  35.06 
 
 
523 aa  148  2.0000000000000003e-34  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00390297  n/a   
 
 
-
 
NC_010172  Mext_4449  metal-dependent phosphohydrolase  39.81 
 
 
358 aa  147  3e-34  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.508967 
 
 
-
 
NC_009831  Ssed_2209  response regulator receiver modulated metal dependent phosphohydrolase  35.51 
 
 
526 aa  147  3e-34  Shewanella sediminis HAW-EB3  Bacteria  normal  0.195398  normal 
 
 
-
 
NC_011757  Mchl_4913  response regulator receiver modulated metal dependent phosphohydrolase  39.81 
 
 
354 aa  147  3e-34  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.478904  normal  0.760596 
 
 
-
 
NC_004347  SO_2366  response regulator  35.25 
 
 
525 aa  147  4.0000000000000006e-34  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009654  Mmwyl1_2382  response regulator receiver modulated metal dependent phosphohydrolase  39.5 
 
 
359 aa  147  4.0000000000000006e-34  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_009901  Spea_0629  response regulator receiver modulated metal dependent phosphohydrolase  37.67 
 
 
339 aa  147  5e-34  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_2799  metal dependent phosphohydrolase  38.64 
 
 
462 aa  146  6e-34  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_0479  response regulator receiver modulated metal dependent phosphohydrolase  34.81 
 
 
350 aa  146  6e-34  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_2105  response regulator receiver modulated metal dependent phosphohydrolase  35.56 
 
 
525 aa  146  6e-34  Shewanella sp. ANA-3  Bacteria  hitchhiker  0.00173233  normal  0.407049 
 
 
-
 
NC_011138  MADE_01215  Response regulator  35.48 
 
 
509 aa  146  6e-34  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.204793  n/a   
 
 
-
 
NC_009654  Mmwyl1_0356  response regulator receiver modulated metal dependent phosphohydrolase  39.07 
 
 
360 aa  146  7.0000000000000006e-34  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_003910  CPS_4164  response regulator/phosphatase  39.73 
 
 
352 aa  145  1e-33  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_4003  response regulator  35.45 
 
 
357 aa  145  1e-33  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008700  Sama_1789  response regulator receiver protein  35.56 
 
 
524 aa  145  1e-33  Shewanella amazonensis SB2B  Bacteria  normal  0.0101023  normal  0.210198 
 
 
-
 
NC_011883  Ddes_1054  response regulator receiver modulated metal dependent phosphohydrolase  38.75 
 
 
359 aa  145  2e-33  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_0187  response regulator receiver modulated metal dependent phosphohydrolase  37.27 
 
 
354 aa  145  2e-33  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.0125166 
 
 
-
 
NC_008345  Sfri_2755  response regulator receiver modulated metal dependent phosphohydrolase  35.22 
 
 
520 aa  144  2e-33  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_3816  response regulator receiver modulated metal dependent phosphohydrolase  39.53 
 
 
351 aa  144  2e-33  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.0960158  normal 
 
 
-
 
NC_011901  Tgr7_0081  two component transcriptional regulator, AraC family  36.04 
 
 
399 aa  144  3e-33  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0632  metal dependent phosphohydrolase  39.82 
 
 
654 aa  144  3e-33  Desulfomicrobium baculatum DSM 4028  Bacteria  hitchhiker  0.0000219793  n/a   
 
 
-
 
NC_009972  Haur_3570  metal dependent phosphohydrolase  27.34 
 
 
571 aa  144  3e-33  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_0538  response regulator receiver modulated metal dependent phosphohydrolase  38.14 
 
 
363 aa  143  4e-33  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.973232  normal 
 
 
-
 
NC_007498  Pcar_2753  hypothetical protein  38.65 
 
 
308 aa  144  4e-33  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_1780  response regulator receiver modulated metal dependent phosphohydrolase  39.81 
 
 
525 aa  144  4e-33  Shewanella sediminis HAW-EB3  Bacteria  normal  0.33037  normal 
 
 
-
 
NC_010511  M446_5034  response regulator receiver modulated metal dependent phosphohydrolase  38.43 
 
 
348 aa  143  5e-33  Methylobacterium sp. 4-46  Bacteria  normal  0.749308  hitchhiker  0.00297277 
 
 
-
 
NC_012560  Avin_50640  response regulator with metal dependent phosphohydrolase activity (two-component)  37.73 
 
 
347 aa  143  5e-33  Azotobacter vinelandii DJ  Bacteria  normal  0.121542  n/a   
 
 
-
 
NC_011831  Cagg_2748  metal dependent phosphohydrolase  27.68 
 
 
574 aa  143  5e-33  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.941576  normal 
 
 
-
 
NC_009092  Shew_1882  metal dependent phosphohydrolase  36.49 
 
 
428 aa  143  6e-33  Shewanella loihica PV-4  Bacteria  normal  normal  0.898808 
 
 
-
 
NC_007954  Sden_2546  metal-dependent phosphohydrolase  34.82 
 
 
515 aa  143  7e-33  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_0838  response regulator receiver modulated metal dependent phosphohydrolase  37.5 
 
 
378 aa  142  8e-33  Methylobacterium sp. 4-46  Bacteria  normal  0.8404  normal 
 
 
-
 
NC_009092  Shew_1983  response regulator receiver modulated metal dependent phosphohydrolase  33.2 
 
 
523 aa  142  8e-33  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00722808  normal 
 
 
-
 
NC_011992  Dtpsy_0962  response regulator receiver modulated metal dependent phosphohydrolase  37.87 
 
 
377 aa  142  9e-33  Acidovorax ebreus TPSY  Bacteria  normal  0.115091  n/a   
 
 
-
 
NC_009052  Sbal_2868  response regulator receiver modulated metal dependent phosphohydrolase  33.2 
 
 
513 aa  142  9.999999999999999e-33  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_3509  metal-dependent phosphohydrolase  39.53 
 
 
351 aa  142  9.999999999999999e-33  Methylobacterium extorquens PA1  Bacteria  normal  0.305053  normal 
 
 
-
 
NC_010505  Mrad2831_2085  response regulator receiver modulated metal dependent phosphohydrolase  39.13 
 
 
345 aa  142  9.999999999999999e-33  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.931733  normal  0.012958 
 
 
-
 
NC_007954  Sden_0663  response regulator receiver  37.27 
 
 
340 aa  142  9.999999999999999e-33  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_3014  response regulator receiver modulated metal dependent phosphohydrolase  33.2 
 
 
513 aa  142  9.999999999999999e-33  Shewanella baltica OS195  Bacteria  normal  normal  0.152382 
 
 
-
 
NC_009665  Shew185_2885  response regulator receiver modulated metal dependent phosphohydrolase  33.2 
 
 
513 aa  142  9.999999999999999e-33  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
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