More than 300 homologs were found in PanDaTox collection
for query gene GM21_3720 on replicon NC_012918
Organism: Geobacter sp. M21



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  100 
 
 
224 aa  451  1.0000000000000001e-126  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  97.32 
 
 
224 aa  436  1e-121  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  71.04 
 
 
223 aa  324  6e-88  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0528  two component heavy metal response transcriptional regulator  71.95 
 
 
223 aa  319  1.9999999999999998e-86  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  65.77 
 
 
223 aa  297  1e-79  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  62.5 
 
 
225 aa  286  1e-76  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  63.35 
 
 
225 aa  287  1e-76  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  63.35 
 
 
225 aa  287  1e-76  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  63.35 
 
 
225 aa  287  1e-76  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  63.8 
 
 
225 aa  286  2e-76  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  63.8 
 
 
225 aa  286  2e-76  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  63.35 
 
 
225 aa  285  4e-76  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  62.9 
 
 
226 aa  285  5e-76  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  61.99 
 
 
226 aa  283  1.0000000000000001e-75  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  61.78 
 
 
226 aa  282  2.0000000000000002e-75  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  63.96 
 
 
229 aa  282  3.0000000000000004e-75  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  62.44 
 
 
225 aa  282  3.0000000000000004e-75  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  62.9 
 
 
225 aa  282  3.0000000000000004e-75  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  60 
 
 
226 aa  281  5.000000000000001e-75  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  62.05 
 
 
224 aa  281  6.000000000000001e-75  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  62.9 
 
 
225 aa  281  6.000000000000001e-75  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  61.88 
 
 
226 aa  281  6.000000000000001e-75  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  61.09 
 
 
223 aa  280  1e-74  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  61.88 
 
 
226 aa  280  2e-74  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  61.54 
 
 
225 aa  278  3e-74  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  63.11 
 
 
227 aa  278  5e-74  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  60.63 
 
 
224 aa  276  1e-73  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  60.54 
 
 
228 aa  276  2e-73  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  60.71 
 
 
225 aa  275  3e-73  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  60.18 
 
 
224 aa  275  3e-73  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  60.09 
 
 
226 aa  275  4e-73  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  61.99 
 
 
226 aa  274  6e-73  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  60.81 
 
 
228 aa  273  1.0000000000000001e-72  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  60.81 
 
 
228 aa  273  1.0000000000000001e-72  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  60.81 
 
 
228 aa  273  2.0000000000000002e-72  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  59.91 
 
 
230 aa  271  4.0000000000000004e-72  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  58.11 
 
 
225 aa  271  6e-72  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  58.11 
 
 
225 aa  271  6e-72  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  58.11 
 
 
225 aa  271  6e-72  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  58.56 
 
 
225 aa  271  7e-72  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  61.26 
 
 
228 aa  270  1e-71  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  58.11 
 
 
225 aa  270  2e-71  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  60.09 
 
 
228 aa  270  2e-71  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_011138  MADE_00315  probable two component response regulator transcription regulator protein  59.17 
 
 
227 aa  268  2.9999999999999997e-71  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  60.27 
 
 
219 aa  269  2.9999999999999997e-71  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  60.36 
 
 
228 aa  268  4e-71  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_007347  Reut_A2490  heavy metal response regulator  63.51 
 
 
228 aa  268  4e-71  Ralstonia eutropha JMP134  Bacteria  normal  0.289616  n/a   
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  60.36 
 
 
225 aa  268  4e-71  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_007912  Sde_1948  response regulator receiver domain-containing protein  59.46 
 
 
226 aa  268  5e-71  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.679676 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  58.37 
 
 
226 aa  267  8e-71  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  59.01 
 
 
227 aa  267  1e-70  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  60.36 
 
 
227 aa  265  2.9999999999999995e-70  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_004578  PSPTO_3603  DNA-binding heavy metal response regulator  60.63 
 
 
229 aa  265  4e-70  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.203952  n/a   
 
 
-
 
NC_007005  Psyr_3374  heavy metal response regulator  60.63 
 
 
229 aa  265  5e-70  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  60.36 
 
 
227 aa  265  5e-70  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_006349  BMAA1028  DNA-binding response regulator IrlR  61.09 
 
 
229 aa  263  1e-69  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0282692  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  57.33 
 
 
228 aa  263  1e-69  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_009079  BMA10247_A1180  transcriptional activator IrlR  61.09 
 
 
229 aa  263  1e-69  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0831411  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0030  DNA-binding response regulator IrlR  61.09 
 
 
229 aa  263  1e-69  Burkholderia pseudomallei 1710b  Bacteria  normal  0.122488  n/a   
 
 
-
 
NC_008784  BMASAVP1_0010  transcriptional activator IrlR  61.09 
 
 
229 aa  263  1e-69  Burkholderia mallei SAVP1  Bacteria  normal  0.121051  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1439  transcriptional activator IrlR  61.09 
 
 
229 aa  263  1e-69  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_009075  BURPS668_A1524  transcriptional activator protein IrlR  61.09 
 
 
229 aa  263  1e-69  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_0402  transcriptional activator IrlR  61.09 
 
 
229 aa  263  1e-69  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0800763  n/a   
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  56 
 
 
238 aa  263  2e-69  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  61.26 
 
 
227 aa  262  3e-69  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_2234  two component heavy metal response transcriptional regulator  59.82 
 
 
225 aa  262  3e-69  Pseudomonas mendocina ymp  Bacteria  normal  0.162422  normal 
 
 
-
 
NC_007971  Rmet_6111  regulator protein CopR  62.61 
 
 
228 aa  262  3e-69  Cupriavidus metallidurans CH34  Bacteria  normal  0.110686  normal  0.158568 
 
 
-
 
NC_007492  Pfl01_3379  two component heavy metal response transcriptional regulator  55.2 
 
 
223 aa  262  4e-69  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B1748a  hypothetical protein  57.14 
 
 
223 aa  262  4e-69  Burkholderia xenovorans LB400  Bacteria  normal  0.0697031  normal  0.305387 
 
 
-
 
NC_010676  Bphyt_4933  two component heavy metal response transcriptional regulator, winged helix family  56.7 
 
 
223 aa  261  6e-69  Burkholderia phytofirmans PsJN  Bacteria  normal  0.461594  normal  0.344735 
 
 
-
 
NC_007974  Rmet_4465  two component heavy metal response transcriptional regulator, winged helix family  63.11 
 
 
206 aa  261  6e-69  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0436659 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  54.82 
 
 
230 aa  261  6.999999999999999e-69  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_011313  VSAL_II0197  transcriptional activator protein, response regulator  54.87 
 
 
227 aa  260  8.999999999999999e-69  Aliivibrio salmonicida LFI1238  Bacteria  hitchhiker  0.0086442  n/a   
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  56.77 
 
 
232 aa  260  1e-68  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1742  two component heavy metal response transcriptional regulator, winged helix family  62.61 
 
 
228 aa  260  1e-68  Ralstonia pickettii 12J  Bacteria  normal  normal  0.595604 
 
 
-
 
NC_012880  Dd703_3722  two component heavy metal response transcriptional regulator, winged helix family  57.59 
 
 
223 aa  260  1e-68  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_007650  BTH_II1376  DNA-binding response regulator IrlR  61.09 
 
 
229 aa  260  1e-68  Burkholderia thailandensis E264  Bacteria  normal  0.498923  n/a   
 
 
-
 
NC_007974  Rmet_5672  DNA-binding response regulator  62.16 
 
 
228 aa  260  1e-68  Cupriavidus metallidurans CH34  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_3842  two component heavy metal response transcriptional regulator  59.28 
 
 
227 aa  259  2e-68  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.67414 
 
 
-
 
NC_007511  Bcep18194_B2430  two component heavy metal response transcriptional regulator  59.28 
 
 
227 aa  259  2e-68  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_008061  Bcen_4683  two component heavy metal response transcriptional regulator  59.28 
 
 
228 aa  259  2e-68  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.222547  n/a   
 
 
-
 
NC_008543  Bcen2424_3680  two component heavy metal response transcriptional regulator  59.28 
 
 
228 aa  259  2e-68  Burkholderia cenocepacia HI2424  Bacteria  normal  0.224842  normal 
 
 
-
 
NC_007963  Csal_0102  two component heavy metal response transcriptional regulator  59.01 
 
 
223 aa  259  3e-68  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.753235  n/a   
 
 
-
 
NC_010070  Bmul_6173  two component heavy metal response transcriptional regulator  59.28 
 
 
228 aa  259  3e-68  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.400074 
 
 
-
 
NC_010681  Bphyt_1510  two component heavy metal response transcriptional regulator, winged helix family  59.91 
 
 
227 aa  258  4e-68  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  55.86 
 
 
223 aa  258  4e-68  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  55.86 
 
 
223 aa  258  5.0000000000000005e-68  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_1675  two component heavy metal response transcriptional regulator  58.93 
 
 
226 aa  258  6e-68  Pseudomonas putida W619  Bacteria  normal  0.294903  normal 
 
 
-
 
NC_007952  Bxe_B0708  two component heavy metal response transcriptional regulator  59.73 
 
 
226 aa  258  6e-68  Burkholderia xenovorans LB400  Bacteria  normal  0.328024  normal  0.9016 
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  57.66 
 
 
232 aa  257  1e-67  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  55.86 
 
 
223 aa  257  1e-67  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_007951  Bxe_A2960  two component heavy metal response transcriptional regulator  59.46 
 
 
227 aa  256  2e-67  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_011667  Tmz1t_2388  heavy metal response regulator  59.29 
 
 
228 aa  255  3e-67  Thauera sp. MZ1T  Bacteria  decreased coverage  0.000142984  normal  0.119734 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  55.41 
 
 
223 aa  255  3e-67  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_011662  Tmz1t_2101  two component heavy metal response transcriptional regulator, winged helix family  59.29 
 
 
228 aa  255  3e-67  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  55.41 
 
 
223 aa  255  3e-67  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  57.08 
 
 
228 aa  255  4e-67  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  60.44 
 
 
242 aa  254  5e-67  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_64570  two-component response regulator  59.91 
 
 
229 aa  254  7e-67  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_009656  PSPA7_5607  two-component response regulator  60.36 
 
 
229 aa  254  8e-67  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
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