More than 300 homologs were found in PanDaTox collection
for query gene Mext_3346 on replicon NC_010172
Organism: Methylobacterium extorquens PA1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010172  Mext_3346  binding-protein-dependent transport systems inner membrane component  100 
 
 
291 aa  557  1e-158  Methylobacterium extorquens PA1  Bacteria  normal  0.252204  normal 
 
 
-
 
NC_011757  Mchl_3671  binding-protein-dependent transport systems inner membrane component  97.91 
 
 
287 aa  476  1e-133  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.0347715  normal 
 
 
-
 
NC_010725  Mpop_4185  binding-protein-dependent transport systems inner membrane component  90.81 
 
 
283 aa  437  1e-121  Methylobacterium populi BJ001  Bacteria  normal  0.321257  normal 
 
 
-
 
NC_002947  PP_0208  nitrate ABC transporter, permease protein, putative  72.8 
 
 
260 aa  352  5e-96  Pseudomonas putida KT2440  Bacteria  normal  normal  0.473726 
 
 
-
 
NC_007492  Pfl01_3160  binding-protein dependent transport system inner membrane protein  73.28 
 
 
274 aa  350  1e-95  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.913146  normal 
 
 
-
 
NC_010501  PputW619_5010  binding-protein-dependent transport systems inner membrane component  72.4 
 
 
260 aa  335  3.9999999999999995e-91  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_008062  Bcen_6102  binding-protein-dependent transport systems inner membrane component  68.65 
 
 
291 aa  325  5e-88  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008542  Bcen2424_1975  binding-protein-dependent transport systems inner membrane component  68.65 
 
 
291 aa  325  5e-88  Burkholderia cenocepacia HI2424  Bacteria  normal  0.690359  n/a   
 
 
-
 
NC_010508  Bcenmc03_1999  binding-protein-dependent transport systems inner membrane component  68.65 
 
 
291 aa  313  1.9999999999999998e-84  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_1295  binding-protein-dependent transport systems inner membrane component  72.38 
 
 
290 aa  305  4.0000000000000004e-82  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.0425684  normal  0.379949 
 
 
-
 
NC_009485  BBta_4879  putative ABC transporter, permease protein  66.4 
 
 
263 aa  298  9e-80  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.132635 
 
 
-
 
NC_007778  RPB_1473  binding-protein dependent transport system inner membrane protein  49.8 
 
 
306 aa  242  5e-63  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0411979  normal 
 
 
-
 
NC_011757  Mchl_4201  binding-protein-dependent transport systems inner membrane component  47.12 
 
 
305 aa  242  7e-63  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010510  Mrad2831_6154  binding-protein-dependent transport systems inner membrane component  47.18 
 
 
295 aa  238  1e-61  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_007406  Nwi_0673  binding-protein dependent transport system inner membrane protein  50.38 
 
 
275 aa  234  1.0000000000000001e-60  Nitrobacter winogradskyi Nb-255  Bacteria  normal  0.0666321  normal  0.331074 
 
 
-
 
NC_009720  Xaut_2085  binding-protein-dependent transport systems inner membrane component  46.61 
 
 
319 aa  233  2.0000000000000002e-60  Xanthobacter autotrophicus Py2  Bacteria  normal  normal  0.0787698 
 
 
-
 
NC_013131  Caci_3787  binding-protein-dependent transport systems inner membrane component  44.29 
 
 
314 aa  214  9.999999999999999e-55  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_2216  binding-protein-dependent transport systems inner membrane component  41.04 
 
 
314 aa  198  9e-50  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.82677  normal  0.484673 
 
 
-
 
NC_008554  Sfum_2218  binding-protein-dependent transport systems inner membrane component  37.29 
 
 
290 aa  181  1e-44  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.484673 
 
 
-
 
NC_008825  Mpe_A0924  ABC transporter permease protein  45 
 
 
258 aa  176  5e-43  Methylibium petroleiphilum PM1  Bacteria  normal  0.175022  normal 
 
 
-
 
NC_008825  Mpe_A0926  nitrate ABC transporter, permease protein, putative  40.3 
 
 
274 aa  172  5e-42  Methylibium petroleiphilum PM1  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_6545  ABC transporter permease  46.56 
 
 
269 aa  162  4.0000000000000004e-39  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.276106 
 
 
-
 
NC_010511  M446_0464  binding-protein-dependent transport systems inner membrane component  45.95 
 
 
288 aa  161  1e-38  Methylobacterium sp. 4-46  Bacteria  normal  0.349721  hitchhiker  0.00645779 
 
 
-
 
NC_007953  Bxe_C0735  nitrate/sulfonate/bicarbonate ABC transporter inner membrane protein  37.21 
 
 
273 aa  157  2e-37  Burkholderia xenovorans LB400  Bacteria  normal  0.714635  normal 
 
 
-
 
NC_009635  Maeo_0992  binding-protein-dependent transport systems inner membrane component  44.44 
 
 
254 aa  157  2e-37  Methanococcus aeolicus Nankai-3  Archaea  normal  n/a   
 
 
-
 
NC_011004  Rpal_4641  binding-protein-dependent transport systems inner membrane component  36.94 
 
 
277 aa  154  1e-36  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.750363  n/a   
 
 
-
 
NC_010511  M446_0397  binding-protein-dependent transport systems inner membrane component  44.1 
 
 
285 aa  152  7e-36  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.987071 
 
 
-
 
NC_009634  Mevan_0512  binding-protein-dependent transport systems inner membrane component  42.33 
 
 
253 aa  151  1e-35  Methanococcus vannielii SB  Archaea  normal  n/a   
 
 
-
 
NC_011887  Mnod_7932  binding-protein-dependent transport systems inner membrane component  42.62 
 
 
283 aa  151  1e-35  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_007651  BTH_I2500  aliphatic sulfonate ABC transporter, permease protein  43.51 
 
 
268 aa  145  7.0000000000000006e-34  Burkholderia thailandensis E264  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_1108  binding-protein-dependent transport systems inner membrane component  36.65 
 
 
255 aa  145  7.0000000000000006e-34  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal  0.135552 
 
 
-
 
NC_009074  BURPS668_1822  aliphatic sulfonates ABC transporter, permease protein  41.63 
 
 
269 aa  145  8.000000000000001e-34  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_4568  binding-protein-dependent transport systems inner membrane component  39.92 
 
 
286 aa  145  1e-33  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_009076  BURPS1106A_1837  aliphatic sulfonates ABC transporter, permease protein  42.06 
 
 
269 aa  144  2e-33  Burkholderia pseudomallei 1106a  Bacteria  normal  0.669476  n/a   
 
 
-
 
NC_006348  BMA1238  aliphatic sulfonate ABC transporter, permease protein  42.06 
 
 
273 aa  144  2e-33  Burkholderia mallei ATCC 23344  Bacteria  normal  0.466833  n/a   
 
 
-
 
NC_007434  BURPS1710b_1990  aliphatic sulfonates ABC transporter, permease protein  42.06 
 
 
273 aa  144  2e-33  Burkholderia pseudomallei 1710b  Bacteria  normal  0.088895  n/a   
 
 
-
 
NC_009080  BMA10247_0780  aliphatic sulfonate ABC transporter, permease protein  42.06 
 
 
273 aa  144  2e-33  Burkholderia mallei NCTC 10247  Bacteria  normal  0.175921  n/a   
 
 
-
 
NC_008785  BMASAVP1_A1724  aliphatic sulfonate ABC transporter, permease protein  42.06 
 
 
273 aa  144  2e-33  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_008836  BMA10229_A0381  aliphatic sulfonate ABC transporter, permease protein  42.06 
 
 
273 aa  144  2e-33  Burkholderia mallei NCTC 10229  Bacteria  normal  0.410212  n/a   
 
 
-
 
NC_009720  Xaut_4051  binding-protein-dependent transport systems inner membrane component  38.74 
 
 
273 aa  143  3e-33  Xanthobacter autotrophicus Py2  Bacteria  normal  normal  0.395379 
 
 
-
 
NC_007510  Bcep18194_A4705  nitrate/sulfonate/bicarbonate ABC transporter periplasmic ligand-binding protein  41.13 
 
 
270 aa  142  5e-33  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_010681  Bphyt_1745  binding-protein-dependent transport systems inner membrane component  39.57 
 
 
280 aa  142  8e-33  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_1261  binding-protein-dependent transport systems inner membrane component  40.86 
 
 
293 aa  142  9e-33  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.113651  normal 
 
 
-
 
NC_011004  Rpal_2404  nitrate ABC transporter, inner membrane subunit  38.65 
 
 
279 aa  140  1.9999999999999998e-32  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.105129  n/a   
 
 
-
 
NC_010508  Bcenmc03_1539  binding-protein-dependent transport systems inner membrane component  40.32 
 
 
270 aa  140  1.9999999999999998e-32  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.0890555  normal 
 
 
-
 
NC_007778  RPB_2055  nitrate transport permease  41.53 
 
 
279 aa  140  1.9999999999999998e-32  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.562067  normal 
 
 
-
 
NC_007948  Bpro_2935  binding-protein-dependent transport systems inner membrane component  39.9 
 
 
252 aa  140  1.9999999999999998e-32  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_008060  Bcen_1083  binding-protein-dependent transport systems inner membrane component  40.32 
 
 
270 aa  140  1.9999999999999998e-32  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008542  Bcen2424_1563  binding-protein-dependent transport systems inner membrane component  40.32 
 
 
270 aa  140  1.9999999999999998e-32  Burkholderia cenocepacia HI2424  Bacteria  normal  n/a   
 
 
-
 
NC_010622  Bphy_1648  binding-protein-dependent transport systems inner membrane component  39.57 
 
 
283 aa  141  1.9999999999999998e-32  Burkholderia phymatum STM815  Bacteria  normal  0.189471  normal  0.0804385 
 
 
-
 
NC_010084  Bmul_1669  binding-protein-dependent transport systems inner membrane component  40.32 
 
 
273 aa  140  3e-32  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.5369  normal  0.169212 
 
 
-
 
NC_012912  Dd1591_1673  binding-protein-dependent transport systems inner membrane component  39.07 
 
 
263 aa  139  3.9999999999999997e-32  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_007955  Mbur_2132  ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit  34.71 
 
 
262 aa  139  3.9999999999999997e-32  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_008463  PA14_19570  ABC transporter permease  37.21 
 
 
262 aa  139  4.999999999999999e-32  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_007951  Bxe_A2492  ABC aliphatic sulfonates transporter, innermembrane subunit  38.72 
 
 
280 aa  139  6e-32  Burkholderia xenovorans LB400  Bacteria  normal  normal  0.773133 
 
 
-
 
NC_008390  Bamb_1464  binding-protein-dependent transport systems inner membrane component  38.72 
 
 
270 aa  139  6e-32  Burkholderia ambifaria AMMD  Bacteria  normal  0.0183453  n/a   
 
 
-
 
NC_009708  YpsIP31758_1848  ABC transporter permease  42.33 
 
 
273 aa  138  8.999999999999999e-32  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_009485  BBta_3299  putative sulfonate ABC transporter, permease protein  34.92 
 
 
286 aa  138  8.999999999999999e-32  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.201269  normal  0.262094 
 
 
-
 
NC_010465  YPK_1957  binding-protein-dependent transport systems inner membrane component  42.33 
 
 
273 aa  138  8.999999999999999e-32  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_0231  binding-protein-dependent transport systems inner membrane component  35.14 
 
 
279 aa  138  1e-31  Pseudomonas putida KT2440  Bacteria  normal  0.33405  hitchhiker  0.000710194 
 
 
-
 
NC_010511  M446_5130  binding-protein-dependent transport systems inner membrane component  36.71 
 
 
272 aa  137  1e-31  Methylobacterium sp. 4-46  Bacteria  normal  0.612608  normal  0.0470724 
 
 
-
 
NC_010172  Mext_1261  binding-protein-dependent transport systems inner membrane component  39.13 
 
 
273 aa  137  1e-31  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.306936 
 
 
-
 
NC_011757  Mchl_1422  binding-protein-dependent transport systems inner membrane component  39.13 
 
 
273 aa  137  1e-31  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_1211  binding-protein-dependent transport systems inner membrane component  38.49 
 
 
273 aa  138  1e-31  Methylobacterium populi BJ001  Bacteria  normal  0.132759  normal  0.452833 
 
 
-
 
NC_012917  PC1_0024  binding-protein-dependent transport systems inner membrane component  36.86 
 
 
264 aa  138  1e-31  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_009637  MmarC7_0444  binding-protein-dependent transport systems inner membrane component  37.67 
 
 
253 aa  138  1e-31  Methanococcus maripaludis C7  Archaea  normal  normal 
 
 
-
 
NC_009656  PSPA7_1684  ABC transporter permease  36.78 
 
 
262 aa  137  2e-31  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_009135  MmarC5_0393  binding-protein-dependent transport systems inner membrane component  44.58 
 
 
253 aa  137  2e-31  Methanococcus maripaludis C5  Archaea  normal  0.0876322  n/a   
 
 
-
 
NC_009485  BBta_5414  putative nitrate ABC transporter (permease protein) (ntrB-like protein)  34.63 
 
 
279 aa  137  2e-31  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.481789  normal 
 
 
-
 
NC_013421  Pecwa_0030  binding-protein-dependent transport systems inner membrane component  35.78 
 
 
264 aa  137  2e-31  Pectobacterium wasabiae WPP163  Bacteria  normal  0.050552  n/a   
 
 
-
 
NC_010322  PputGB1_0263  binding-protein-dependent transport systems inner membrane component  38.16 
 
 
265 aa  137  3.0000000000000003e-31  Pseudomonas putida GB-1  Bacteria  normal  0.791848  normal 
 
 
-
 
NC_010501  PputW619_4973  binding-protein-dependent transport systems inner membrane component  38.16 
 
 
265 aa  137  3.0000000000000003e-31  Pseudomonas putida W619  Bacteria  normal  0.0722896  normal  0.022026 
 
 
-
 
NC_007355  Mbar_A1031  sulfonate ABC transporter, permease protein  33.47 
 
 
261 aa  136  4e-31  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_013422  Hneap_2205  nitrate ABC transporter, inner membrane subunit  38.1 
 
 
280 aa  136  4e-31  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_012880  Dd703_1642  binding-protein-dependent transport systems inner membrane component  38.14 
 
 
263 aa  136  4e-31  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_0254  binding-protein dependent transport system inner membrane protein  35.79 
 
 
279 aa  135  5e-31  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.57663 
 
 
-
 
NC_011832  Mpal_1076  binding-protein-dependent transport systems inner membrane component  40.74 
 
 
269 aa  136  5e-31  Methanosphaerula palustris E1-9c  Archaea  normal  0.406887  normal  0.454808 
 
 
-
 
NC_012850  Rleg_2304  binding-protein-dependent transport systems inner membrane component  34.91 
 
 
278 aa  135  8e-31  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.37818 
 
 
-
 
NC_009512  Pput_0254  binding-protein-dependent transport systems inner membrane component  37.72 
 
 
265 aa  135  9e-31  Pseudomonas putida F1  Bacteria  normal  0.293544  normal  0.0445843 
 
 
-
 
NC_002947  PP_0239  binding-protein-dependent transport systems inner membrane component  37.72 
 
 
265 aa  135  9.999999999999999e-31  Pseudomonas putida KT2440  Bacteria  normal  hitchhiker  0.00756787 
 
 
-
 
NC_009439  Pmen_4321  binding-protein-dependent transport systems inner membrane component  37.74 
 
 
264 aa  134  9.999999999999999e-31  Pseudomonas mendocina ymp  Bacteria  normal  normal  0.154719 
 
 
-
 
NC_012791  Vapar_2975  binding-protein-dependent transport systems inner membrane component  38.94 
 
 
284 aa  135  9.999999999999999e-31  Variovorax paradoxus S110  Bacteria  normal  0.27836  n/a   
 
 
-
 
NC_013521  Sked_16930  ABC-type nitrate/sulfonate/bicarbonate transport system, permease component  35.96 
 
 
322 aa  135  9.999999999999999e-31  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.327  normal  0.410158 
 
 
-
 
NC_009708  YpsIP31758_0355  putative ABC aliphatic sulfonates transporter, permease subunit  38.16 
 
 
264 aa  135  9.999999999999999e-31  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_009975  MmarC6_1476  binding-protein-dependent transport systems inner membrane component  44.24 
 
 
253 aa  135  9.999999999999999e-31  Methanococcus maripaludis C6  Archaea  normal  n/a   
 
 
-
 
NC_010465  YPK_0423  binding-protein-dependent transport systems inner membrane component  38.16 
 
 
264 aa  135  9.999999999999999e-31  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_2882  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
268 aa  134  9.999999999999999e-31  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.80309  n/a   
 
 
-
 
NC_011988  Avi_5468  ABC transporter membrane spanning protein (aliphatic sulphonate)  39.24 
 
 
284 aa  135  9.999999999999999e-31  Agrobacterium vitis S4  Bacteria  normal  0.165676  n/a   
 
 
-
 
NC_009436  Ent638_1453  alkanesulfonate transporter permease subunit  35.74 
 
 
263 aa  134  9.999999999999999e-31  Enterobacter sp. 638  Bacteria  normal  normal 
 
 
-
 
NC_009720  Xaut_3464  binding-protein-dependent transport systems inner membrane component  34.77 
 
 
294 aa  134  1.9999999999999998e-30  Xanthobacter autotrophicus Py2  Bacteria  normal  0.136656  normal 
 
 
-
 
NC_007492  Pfl01_5412  binding-protein dependent transport system inner membrane protein  37.28 
 
 
260 aa  134  1.9999999999999998e-30  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.210037  hitchhiker  0.00191971 
 
 
-
 
NC_011883  Ddes_0573  binding-protein-dependent transport systems inner membrane component  37.07 
 
 
277 aa  133  3e-30  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_4981  binding-protein-dependent transport systems inner membrane component  34.06 
 
 
279 aa  133  3e-30  Pseudomonas putida W619  Bacteria  normal  normal  0.588836 
 
 
-
 
NC_009720  Xaut_1210  binding-protein-dependent transport systems inner membrane component  36.93 
 
 
315 aa  133  3.9999999999999996e-30  Xanthobacter autotrophicus Py2  Bacteria  normal  normal 
 
 
-
 
NC_009832  Spro_1736  binding-protein-dependent transport systems inner membrane component  37.68 
 
 
264 aa  133  3.9999999999999996e-30  Serratia proteamaculans 568  Bacteria  normal  0.440066  normal  0.144233 
 
 
-
 
NC_009512  Pput_0246  binding-protein-dependent transport systems inner membrane component  36.82 
 
 
279 aa  133  3.9999999999999996e-30  Pseudomonas putida F1  Bacteria  normal  0.0570948  normal  0.0921514 
 
 
-
 
NC_008340  Mlg_1704  nitrate ABC transporter, inner membrane subunit  34.55 
 
 
311 aa  133  3.9999999999999996e-30  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal 
 
 
-
 
NC_009428  Rsph17025_0765  binding-protein-dependent transport systems inner membrane component  37.25 
 
 
265 aa  133  3.9999999999999996e-30  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_014150  Bmur_0154  binding-protein-dependent transport systems inner membrane component  35.71 
 
 
264 aa  132  5e-30  Brachyspira murdochii DSM 12563  Bacteria  normal  n/a   
 
 
-
 
NC_013161  Cyan8802_4458  nitrate ABC transporter, inner membrane subunit  32.37 
 
 
277 aa  132  6e-30  Cyanothece sp. PCC 8802  Bacteria  normal  0.698055  normal  0.534513 
 
 
-
 
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