More than 300 homologs were found in PanDaTox collection
for query gene Amir_4014 on replicon NC_013093
Organism: Actinosynnema mirum DSM 43827



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013093  Amir_4014  putative two component transcriptional regulator, winged helix family  100 
 
 
166 aa  317  6e-86  Actinosynnema mirum DSM 43827  Bacteria  normal  0.572334  n/a   
 
 
-
 
NC_013093  Amir_1805  putative two component transcriptional regulator, winged helix family  51.27 
 
 
170 aa  123  1e-27  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009380  Strop_2147  transcriptional regulator domain-containing protein  42.01 
 
 
203 aa  94  9e-19  Salinispora tropica CNB-440  Bacteria  normal  0.162923  normal  0.29273 
 
 
-
 
NC_009953  Sare_2299  winged helix family two component response transcriptional regulator  41.42 
 
 
203 aa  93.6  1e-18  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00499113 
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  47.73 
 
 
223 aa  91.3  6e-18  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_013947  Snas_0207  putative two component transcriptional regulator, winged helix family  49.53 
 
 
180 aa  89.7  1e-17  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.183143  normal  0.472941 
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  45.45 
 
 
223 aa  88.6  4e-17  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  45.45 
 
 
223 aa  86.7  1e-16  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_005957  BT9727_1191  response regulator  44.32 
 
 
223 aa  85.9  2e-16  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  44.32 
 
 
223 aa  85.9  2e-16  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  44.32 
 
 
223 aa  85.9  2e-16  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  44.32 
 
 
223 aa  85.5  3e-16  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  44.32 
 
 
223 aa  85.5  3e-16  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  44.32 
 
 
223 aa  85.1  4e-16  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  44.32 
 
 
223 aa  85.1  4e-16  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  46.34 
 
 
223 aa  84.3  8e-16  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013235  Namu_4983  putative two component transcriptional regulator, winged helix family  58.9 
 
 
232 aa  83.6  0.000000000000001  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_009953  Sare_0337  winged helix family two component response transcriptional regulator  52.87 
 
 
239 aa  83.2  0.000000000000001  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.0279779 
 
 
-
 
NC_008578  Acel_2025  response regulator receiver protein  50.54 
 
 
261 aa  83.6  0.000000000000001  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_009380  Strop_0293  winged helix family two component response transcriptional regulator  52.87 
 
 
239 aa  82  0.000000000000003  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_3419  putative two component transcriptional regulator, winged helix family  51.72 
 
 
240 aa  81.6  0.000000000000004  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_4376  putative two component transcriptional regulator, winged helix family  52.33 
 
 
255 aa  81.3  0.000000000000005  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_2724  putative two component transcriptional regulator, winged helix family  56.16 
 
 
232 aa  81.3  0.000000000000006  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00387379 
 
 
-
 
NC_008541  Arth_3012  response regulator receiver protein  56.16 
 
 
232 aa  81.3  0.000000000000006  Arthrobacter sp. FB24  Bacteria  normal  0.721979  n/a   
 
 
-
 
NC_014165  Tbis_0453  putative winged helix family two component transcriptional regulator  57.53 
 
 
251 aa  80.9  0.000000000000007  Thermobispora bispora DSM 43833  Bacteria  normal  0.190844  normal  0.275136 
 
 
-
 
NC_013595  Sros_0895  response regulator receiver protein  57.53 
 
 
237 aa  80.9  0.000000000000007  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_6372  putative two component transcriptional regulator, winged helix family  57.53 
 
 
236 aa  80.1  0.00000000000001  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_012791  Vapar_2316  two component transcriptional regulator PhoB, winged helix family  46.67 
 
 
230 aa  79.7  0.00000000000002  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_2737  transcriptional regulatory protein  56.16 
 
 
253 aa  79.3  0.00000000000002  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  42.39 
 
 
227 aa  79.7  0.00000000000002  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_011992  Dtpsy_1491  two component transcriptional regulator PhoB, winged helix family  42.71 
 
 
235 aa  79.3  0.00000000000002  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_008752  Aave_2631  two component transcriptional regulator  44.44 
 
 
235 aa  79.7  0.00000000000002  Acidovorax citrulli AAC00-1  Bacteria  normal  0.552533  normal  0.0653315 
 
 
-
 
NC_008782  Ajs_2367  two component transcriptional regulator  42.71 
 
 
235 aa  79.3  0.00000000000002  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_0595  putative two component transcriptional regulator, winged helix family  56.16 
 
 
237 aa  79  0.00000000000003  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_4240  transcriptional regulator domain-containing protein  57.53 
 
 
257 aa  79  0.00000000000003  Nocardioides sp. JS614  Bacteria  normal  0.466466  n/a   
 
 
-
 
NC_008781  Pnap_2201  two component transcriptional regulator  49.37 
 
 
242 aa  78.6  0.00000000000003  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.153982  normal 
 
 
-
 
NC_013757  Gobs_4646  putative two component transcriptional regulator, winged helix family  49.43 
 
 
249 aa  79  0.00000000000003  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_4913  two component transcriptional regulator  46.67 
 
 
231 aa  78.2  0.00000000000005  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.121364 
 
 
-
 
NC_013169  Ksed_03550  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  52.22 
 
 
261 aa  77.4  0.00000000000008  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.329191  normal 
 
 
-
 
NC_013216  Dtox_2022  two component transcriptional regulator, winged helix family  47.56 
 
 
227 aa  77.4  0.00000000000009  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.203611  normal  0.416027 
 
 
-
 
NC_014151  Cfla_3090  putative two component transcriptional regulator, winged helix family  56.16 
 
 
241 aa  77.4  0.00000000000009  Cellulomonas flavigena DSM 20109  Bacteria  normal  hitchhiker  0.0000121276 
 
 
-
 
NC_013440  Hoch_6843  putative two component transcriptional regulator, winged helix family  48.05 
 
 
258 aa  77  0.0000000000001  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_6176  winged helix family two component response transcriptional regulator  56.16 
 
 
247 aa  77  0.0000000000001  Frankia sp. EAN1pec  Bacteria  normal  normal  0.186762 
 
 
-
 
NC_007777  Francci3_0443  response regulator receiver protein  56.16 
 
 
250 aa  76.6  0.0000000000001  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_3069  two component transcriptional regulator  44.57 
 
 
230 aa  77  0.0000000000001  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.0000000467461  n/a   
 
 
-
 
NC_010816  BLD_1194  putative response regulator  53.42 
 
 
266 aa  76.6  0.0000000000001  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_5611  two component transcriptional regulator, winged helix family  40.23 
 
 
235 aa  75.9  0.0000000000002  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.736991 
 
 
-
 
NC_013530  Xcel_3035  putative two component transcriptional regulator, winged helix family  54.79 
 
 
243 aa  76.3  0.0000000000002  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_0879  putative two component transcriptional regulator, winged helix family  51.81 
 
 
259 aa  76.3  0.0000000000002  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.249855  hitchhiker  0.00478466 
 
 
-
 
NC_013174  Jden_0439  putative two component transcriptional regulator, winged helix family  55.71 
 
 
248 aa  76.3  0.0000000000002  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.190602 
 
 
-
 
NC_008786  Veis_1288  two component transcriptional regulator  46.67 
 
 
238 aa  76.3  0.0000000000002  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_013203  Apar_0432  putative two component transcriptional regulator, winged helix family  54.17 
 
 
224 aa  75.5  0.0000000000003  Atopobium parvulum DSM 20469  Bacteria  hitchhiker  0.000490664  normal 
 
 
-
 
NC_008261  CPF_0226  DNA-binding response regulator  39.53 
 
 
223 aa  75.5  0.0000000000003  Clostridium perfringens ATCC 13124  Bacteria  normal  0.232655  n/a   
 
 
-
 
NC_008262  CPR_0226  DNA-binding response regulator  39.53 
 
 
223 aa  75.5  0.0000000000003  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_008726  Mvan_5097  response regulator receiver protein  54.79 
 
 
267 aa  75.5  0.0000000000003  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_012793  GWCH70_1924  two component transcriptional regulator, winged helix family  44.58 
 
 
225 aa  75.1  0.0000000000004  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_04930  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  54.79 
 
 
249 aa  75.5  0.0000000000004  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.793732  normal 
 
 
-
 
NC_013165  Shel_19870  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  56.34 
 
 
224 aa  75.5  0.0000000000004  Slackia heliotrinireducens DSM 20476  Bacteria  normal  0.931606  normal 
 
 
-
 
NC_014158  Tpau_3545  putative two component transcriptional regulator, winged helix family  49.43 
 
 
243 aa  75.1  0.0000000000004  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.61486  n/a   
 
 
-
 
NC_013946  Mrub_0302  two component transcriptional regulator, winged helix family  50.56 
 
 
221 aa  75.1  0.0000000000004  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_8253  putative two component transcriptional regulator, winged helix family  53.42 
 
 
264 aa  75.1  0.0000000000004  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  39.62 
 
 
233 aa  75.1  0.0000000000004  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_3935  transcriptional regulator domain protein  54.79 
 
 
270 aa  75.1  0.0000000000004  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_008146  Mmcs_4525  response regulator receiver protein  54.79 
 
 
257 aa  75.5  0.0000000000004  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_011886  Achl_0805  putative two component transcriptional regulator, winged helix family  41.23 
 
 
288 aa  75.1  0.0000000000004  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_008705  Mkms_4612  response regulator receiver protein  54.79 
 
 
257 aa  75.5  0.0000000000004  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_008709  Ping_2232  two component transcriptional regulator, winged helix family protein  48.15 
 
 
227 aa  75.1  0.0000000000004  Psychromonas ingrahamii 37  Bacteria  normal  0.326614  normal  0.43086 
 
 
-
 
NC_009077  Mjls_4908  response regulator receiver protein  54.79 
 
 
257 aa  75.5  0.0000000000004  Mycobacterium sp. JLS  Bacteria  normal  normal 
 
 
-
 
NC_009338  Mflv_1650  response regulator receiver protein  54.79 
 
 
278 aa  75.1  0.0000000000004  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.0110992  normal 
 
 
-
 
NC_013037  Dfer_4011  two component transcriptional regulator, winged helix family  38.78 
 
 
236 aa  75.1  0.0000000000004  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.0268606  normal 
 
 
-
 
NC_011725  BCB4264_A5385  DNA-binding response regulator  38.89 
 
 
223 aa  74.7  0.0000000000005  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B5569  DNA-binding response regulator  38.89 
 
 
223 aa  74.7  0.0000000000005  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_0588  two component transcriptional regulator, winged helix family  50 
 
 
226 aa  74.7  0.0000000000005  Geobacter lovleyi SZ  Bacteria  normal  0.944339  n/a   
 
 
-
 
NC_011658  BCAH187_A5433  DNA-binding response regulator  40 
 
 
223 aa  74.7  0.0000000000005  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_6823  putative two component transcriptional regulator, winged helix family  54.79 
 
 
250 aa  74.7  0.0000000000006  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1600  two component transcriptional regulator  42.05 
 
 
224 aa  74.7  0.0000000000006  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000237714  n/a   
 
 
-
 
NC_010682  Rpic_3737  two component transcriptional regulator, winged helix family  55.13 
 
 
278 aa  74.3  0.0000000000007  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_012856  Rpic12D_3415  two component transcriptional regulator, winged helix family  55.13 
 
 
280 aa  74.3  0.0000000000007  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_013204  Elen_2015  putative two component transcriptional regulator, winged helix family  53.25 
 
 
224 aa  73.9  0.0000000000008  Eggerthella lenta DSM 2243  Bacteria  normal  0.0839248  hitchhiker  0.0000000000000188648 
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  45.26 
 
 
232 aa  73.9  0.0000000000008  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_2918  two component transcriptional regulator, winged helix family  44.32 
 
 
232 aa  73.9  0.0000000000008  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_007908  Rfer_0578  two component transcriptional regulator  48.81 
 
 
240 aa  74.3  0.0000000000008  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_5379  DNA-binding response regulator  38.89 
 
 
223 aa  73.9  0.0000000000009  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_5353  DNA-binding response regulator  38.89 
 
 
223 aa  73.9  0.0000000000009  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011145  AnaeK_0439  two component transcriptional regulator, winged helix family  50.6 
 
 
230 aa  73.9  0.0000000000009  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_0440  two component transcriptional regulator, winged helix family  50.6 
 
 
230 aa  73.9  0.0000000000009  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4959  DNA-binding response regulator  38.89 
 
 
223 aa  73.9  0.0000000000009  Bacillus cereus E33L  Bacteria  hitchhiker  0.000160223  n/a   
 
 
-
 
NC_007644  Moth_0827  two component transcriptional regulator  50 
 
 
256 aa  73.9  0.0000000000009  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00211389  normal  0.244563 
 
 
-
 
NC_013124  Afer_0241  putative two component transcriptional regulator, winged helix family  54.79 
 
 
217 aa  73.9  0.0000000000009  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4944  DNA-binding response regulator  38.89 
 
 
223 aa  73.6  0.000000000001  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.0109954  n/a   
 
 
-
 
NC_011830  Dhaf_1237  two component transcriptional regulator, winged helix family  39.39 
 
 
234 aa  73.6  0.000000000001  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.178035  n/a   
 
 
-
 
NC_009565  TBFG_10833  transcriptional regulatory protein  54.79 
 
 
255 aa  73.6  0.000000000001  Mycobacterium tuberculosis F11  Bacteria  normal  hitchhiker  0.00597919 
 
 
-
 
NC_013159  Svir_37670  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  54.17 
 
 
256 aa  73.2  0.000000000001  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal  0.0528352 
 
 
-
 
NC_007760  Adeh_0411  two component transcriptional regulator  50.6 
 
 
230 aa  73.6  0.000000000001  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_1389  putative two component transcriptional regulator, winged helix family  47.73 
 
 
171 aa  73.6  0.000000000001  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.287988  hitchhiker  0.00961108 
 
 
-
 
NC_007948  Bpro_2257  two component transcriptional regulator  46.84 
 
 
243 aa  73.2  0.000000000001  Polaromonas sp. JS666  Bacteria  normal  0.512842  normal  0.410356 
 
 
-
 
NC_007963  Csal_3253  two component transcriptional regulator  45.65 
 
 
229 aa  73.6  0.000000000001  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_1397  two component transcriptional regulator  46.81 
 
 
261 aa  73.6  0.000000000001  Roseiflexus sp. RS-1  Bacteria  normal  0.0231814  hitchhiker  0.000111966 
 
 
-
 
NC_010184  BcerKBAB4_5055  two component transcriptional regulator  39.33 
 
 
223 aa  73.9  0.000000000001  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_013721  HMPREF0424_0189  transcriptional regulatory protein, C-terminal domain protein  48.1 
 
 
296 aa  73.2  0.000000000002  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
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