More than 300 homologs were found in PanDaTox collection
for query gene Tcur_2293 on replicon NC_013510
Organism: Thermomonospora curvata DSM 43183



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013510  Tcur_2293  HAD-superfamily hydrolase, subfamily IA, variant 3  100 
 
 
218 aa  427  1e-119  Thermomonospora curvata DSM 43183  Bacteria  hitchhiker  0.0000494788  n/a   
 
 
-
 
NC_013595  Sros_5916  HAD family hydrolase  56.4 
 
 
218 aa  228  5e-59  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0345843  normal  0.0351614 
 
 
-
 
NC_014165  Tbis_1853  HAD-superfamily hydrolase  53.3 
 
 
213 aa  218  7.999999999999999e-56  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_2412  HAD-superfamily hydrolase, subfamily IA, variant 3  50.95 
 
 
222 aa  206  2e-52  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_1550  HAD-superfamily hydrolase, subfamily IA, variant 3  48.37 
 
 
249 aa  186  3e-46  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal  0.204001 
 
 
-
 
NC_007777  Francci3_2637  HAD family hydrolase  52.6 
 
 
286 aa  171  1e-41  Frankia sp. CcI3  Bacteria  normal  0.403398  normal  0.292856 
 
 
-
 
NC_008578  Acel_1175  HAD family hydrolase  46.92 
 
 
263 aa  169  4e-41  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_4498  HAD-superfamily hydrolase subfamily IA, variant 3  45.62 
 
 
223 aa  166  2e-40  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.511661  normal  0.0143777 
 
 
-
 
NC_013159  Svir_22200  haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED  44.86 
 
 
217 aa  158  6e-38  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.172111  normal 
 
 
-
 
NC_007333  Tfu_1824  HAD family hydrolase  50.47 
 
 
222 aa  158  7e-38  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_2632  HAD family hydrolase  42.86 
 
 
218 aa  158  7e-38  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_7385  HAD-superfamily hydrolase, subfamily IA  44.92 
 
 
248 aa  157  9e-38  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_4889  HAD family hydrolase  51.39 
 
 
233 aa  157  1e-37  Frankia sp. EAN1pec  Bacteria  normal  0.351284  normal  0.0730929 
 
 
-
 
NC_013235  Namu_2787  HAD-superfamily hydrolase, subfamily IA, variant 3  43.46 
 
 
230 aa  155  4e-37  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.00137861  hitchhiker  0.0000132599 
 
 
-
 
NC_013169  Ksed_13910  haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED  41.35 
 
 
232 aa  152  5e-36  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.491881  normal 
 
 
-
 
NC_009664  Krad_1843  HAD-superfamily hydrolase, subfamily IA, variant 3  46.19 
 
 
241 aa  151  8e-36  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.101722  normal 
 
 
-
 
NC_013093  Amir_2212  HAD-superfamily hydrolase, subfamily IA, variant 3  44.39 
 
 
220 aa  150  1e-35  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013530  Xcel_1481  HAD-superfamily hydrolase, subfamily IA, variant 3  43.06 
 
 
233 aa  144  1e-33  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_2245  HAD-superfamily hydrolase, subfamily IA, variant 3  43.6 
 
 
247 aa  140  1.9999999999999998e-32  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.56873  normal 
 
 
-
 
NC_011886  Achl_1913  HAD-superfamily hydrolase, subfamily IA, variant 3  37.79 
 
 
245 aa  136  2e-31  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00000000014808 
 
 
-
 
NC_008726  Mvan_3473  HAD family hydrolase  40.47 
 
 
243 aa  135  4e-31  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_013521  Sked_20940  haloacid dehalogenase superfamily enzyme, subfamily IA  41.43 
 
 
273 aa  135  7.000000000000001e-31  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.650807 
 
 
-
 
NC_013757  Gobs_2673  HAD-superfamily hydrolase, subfamily IA, variant 3  43.58 
 
 
248 aa  134  9.999999999999999e-31  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.649761  n/a   
 
 
-
 
NC_014151  Cfla_2008  HAD-superfamily hydrolase, subfamily IA, variant 3  41.58 
 
 
213 aa  127  9.000000000000001e-29  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.296794  normal 
 
 
-
 
NC_011831  Cagg_1516  HAD-superfamily hydrolase, subfamily IA, variant 3  41.46 
 
 
227 aa  126  3e-28  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_013441  Gbro_2452  HAD-superfamily hydrolase, subfamily IA, variant 3  44.06 
 
 
232 aa  124  1e-27  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_3054  HAD family hydrolase  40 
 
 
224 aa  122  3e-27  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.751068  normal  0.223571 
 
 
-
 
NC_013174  Jden_1197  HAD-superfamily hydrolase, subfamily IA, variant 3  34.12 
 
 
225 aa  122  4e-27  Jonesia denitrificans DSM 20603  Bacteria  normal  0.0955551  normal  0.148864 
 
 
-
 
NC_013159  Svir_32070  haloacid dehalogenase superfamily enzyme, subfamily IA  40.51 
 
 
227 aa  121  7e-27  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.466176  normal  0.444114 
 
 
-
 
NC_008146  Mmcs_3148  HAD family hydrolase  41.4 
 
 
228 aa  120  1.9999999999999998e-26  Mycobacterium sp. MCS  Bacteria  normal  0.0274068  n/a   
 
 
-
 
NC_008705  Mkms_3210  HAD family hydrolase  41.4 
 
 
228 aa  120  1.9999999999999998e-26  Mycobacterium sp. KMS  Bacteria  normal  0.742759  normal  0.278604 
 
 
-
 
NC_009077  Mjls_3160  HAD family hydrolase  41.4 
 
 
228 aa  120  1.9999999999999998e-26  Mycobacterium sp. JLS  Bacteria  normal  0.0720917  normal  0.533727 
 
 
-
 
NC_008541  Arth_2170  HAD family hydrolase  39.35 
 
 
263 aa  117  9.999999999999999e-26  Arthrobacter sp. FB24  Bacteria  normal  0.156461  n/a   
 
 
-
 
NC_009012  Cthe_3073  HAD family hydrolase  37.1 
 
 
223 aa  117  1.9999999999999998e-25  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.00582956  n/a   
 
 
-
 
NC_009953  Sare_2349  HAD family hydrolase  43.98 
 
 
215 aa  116  3e-25  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.355354 
 
 
-
 
NC_009380  Strop_2232  HAD family hydrolase  45.13 
 
 
233 aa  115  6e-25  Salinispora tropica CNB-440  Bacteria  normal  0.470588  normal 
 
 
-
 
NC_014158  Tpau_2146  HAD-superfamily hydrolase, subfamily IA, variant 3  35.55 
 
 
213 aa  113  2.0000000000000002e-24  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_1912  2-deoxyglucose-6-phosphatase  36.51 
 
 
223 aa  111  7.000000000000001e-24  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.0120822  n/a   
 
 
-
 
NC_009438  Sputcn32_3410  2-deoxyglucose-6-phosphatase  34.9 
 
 
217 aa  108  5e-23  Shewanella putrefaciens CN-32  Bacteria  normal  0.0110715  n/a   
 
 
-
 
NC_004347  SO_0431  2-deoxyglucose-6-phosphatase  35.6 
 
 
217 aa  108  9.000000000000001e-23  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_010816  BLD_1305  beta-phosphoglucomutase  34.18 
 
 
223 aa  107  1e-22  Bifidobacterium longum DJO10A  Bacteria  normal  0.396501  n/a   
 
 
-
 
NC_013721  HMPREF0424_1278  HAD hydrolase, family IA, variant 3  33.93 
 
 
247 aa  107  1e-22  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_013205  Aaci_2469  HAD-superfamily hydrolase, subfamily IA, variant 3  34.43 
 
 
224 aa  107  2e-22  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.618161  n/a   
 
 
-
 
NC_013037  Dfer_4825  HAD-superfamily hydrolase, subfamily IA, variant 3  34.41 
 
 
224 aa  107  2e-22  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_0432  2-deoxyglucose-6-phosphatase  35.6 
 
 
218 aa  106  2e-22  Shewanella sp. ANA-3  Bacteria  unclonable  0.00000000498152  normal 
 
 
-
 
NC_011899  Hore_10160  HAD-superfamily hydrolase, subfamily IA, variant 3  32.57 
 
 
217 aa  106  3e-22  Halothermothrix orenii H 168  Bacteria  normal  0.64096  n/a   
 
 
-
 
NC_011004  Rpal_4817  HAD-superfamily hydrolase, subfamily IA, variant 3  36.17 
 
 
235 aa  106  3e-22  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.821962  n/a   
 
 
-
 
NC_009953  Sare_4356  HAD family hydrolase  37.09 
 
 
233 aa  106  3e-22  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.582602 
 
 
-
 
NC_009380  Strop_3972  HAD family hydrolase  39.49 
 
 
241 aa  105  4e-22  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_013526  Tter_2485  HAD-superfamily hydrolase, subfamily IA, variant 3  36.13 
 
 
238 aa  105  5e-22  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_0437  2-deoxyglucose-6-phosphatase  32.98 
 
 
221 aa  105  5e-22  Shewanella sediminis HAW-EB3  Bacteria  hitchhiker  0.000647119  hitchhiker  0.00000756317 
 
 
-
 
NC_009832  Spro_2125  2-deoxyglucose-6-phosphatase  33.16 
 
 
221 aa  105  7e-22  Serratia proteamaculans 568  Bacteria  normal  0.0177126  hitchhiker  0.00144451 
 
 
-
 
NC_009441  Fjoh_2690  HAD family hydrolase  35.64 
 
 
221 aa  103  1e-21  Flavobacterium johnsoniae UW101  Bacteria  normal  0.365385  n/a   
 
 
-
 
NC_009708  YpsIP31758_1697  2-deoxyglucose-6-phosphatase  34.03 
 
 
221 aa  103  2e-21  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A1419  2-deoxyglucose-6-phosphatase  36.56 
 
 
222 aa  103  2e-21  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.744627  hitchhiker  0.00259415 
 
 
-
 
NC_011205  SeD_A2022  2-deoxyglucose-6-phosphatase  36.56 
 
 
222 aa  103  2e-21  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal 
 
 
-
 
NC_011083  SeHA_C1451  2-deoxyglucose-6-phosphatase  36.56 
 
 
222 aa  103  2e-21  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  0.913842  normal 
 
 
-
 
NC_011080  SNSL254_A1436  2-deoxyglucose-6-phosphatase  36.56 
 
 
222 aa  103  2e-21  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  0.905236  normal 
 
 
-
 
NC_011149  SeAg_B1849  2-deoxyglucose-6-phosphatase  36.56 
 
 
222 aa  103  2e-21  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  hitchhiker  0.0029739  n/a   
 
 
-
 
NC_010465  YPK_1808  2-deoxyglucose-6-phosphatase  34.03 
 
 
221 aa  103  2e-21  Yersinia pseudotuberculosis YPIII  Bacteria  normal  0.417032  n/a   
 
 
-
 
NC_008321  Shewmr4_0436  2-deoxyglucose-6-phosphatase  35.15 
 
 
218 aa  103  3e-21  Shewanella sp. MR-4  Bacteria  unclonable  0.0000000024214  normal 
 
 
-
 
NC_013421  Pecwa_2205  2-deoxyglucose-6-phosphatase  35.98 
 
 
221 aa  102  3e-21  Pectobacterium wasabiae WPP163  Bacteria  normal  0.100097  n/a   
 
 
-
 
NC_007492  Pfl01_1752  HAD family hydrolase  37.63 
 
 
232 aa  102  6e-21  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3593  2-deoxyglucose-6-phosphatase  34.55 
 
 
218 aa  102  6e-21  Shewanella sp. MR-7  Bacteria  unclonable  0.0000011766  normal  0.672534 
 
 
-
 
NC_008148  Rxyl_0905  HAD family hydrolase  34.63 
 
 
204 aa  101  7e-21  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.427836  n/a   
 
 
-
 
NC_009997  Sbal195_4047  2-deoxyglucose-6-phosphatase  34.69 
 
 
219 aa  101  1e-20  Shewanella baltica OS195  Bacteria  hitchhiker  0.0000965281  normal  0.234971 
 
 
-
 
NC_009523  RoseRS_3281  HAD family hydrolase  35.38 
 
 
221 aa  100  2e-20  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_007778  RPB_1286  HAD family hydrolase  36.5 
 
 
229 aa  100  2e-20  Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_1853  HAD family hydrolase  40.93 
 
 
235 aa  100  2e-20  Frankia sp. EAN1pec  Bacteria  normal  0.147437  normal  0.0157174 
 
 
-
 
NC_011725  BCB4264_A4313  hydrolase, haloacid dehalogenase-like family  31.46 
 
 
235 aa  100  2e-20  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_1743  HAD-superfamily hydrolase, subfamily IA, variant 3  31.35 
 
 
227 aa  99.8  3e-20  Geobacillus sp. WCH70  Bacteria  normal  0.293469  n/a   
 
 
-
 
NC_008700  Sama_0381  2-deoxyglucose-6-phosphatase  36.13 
 
 
221 aa  99.8  3e-20  Shewanella amazonensis SB2B  Bacteria  hitchhiker  0.0071153  normal  0.324571 
 
 
-
 
NC_013730  Slin_2846  HAD-superfamily hydrolase, subfamily IA, variant 3  34.55 
 
 
226 aa  99.4  4e-20  Spirosoma linguale DSM 74  Bacteria  normal  0.281035  normal  0.462582 
 
 
-
 
NC_013093  Amir_7029  HAD-superfamily hydrolase, subfamily IA, variant 3  37.06 
 
 
213 aa  99  4e-20  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_1034  hydrolase  34.95 
 
 
217 aa  98.6  6e-20  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_013132  Cpin_5088  beta-phosphoglucomutase  32.87 
 
 
219 aa  98.6  6e-20  Chitinophaga pinensis DSM 2588  Bacteria  decreased coverage  0.00016924  normal  0.408522 
 
 
-
 
NC_003909  BCE_4276  HAD superfamily hydrolase  30.62 
 
 
220 aa  98.6  7e-20  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_010483  TRQ2_1566  HAD family hydrolase  31.49 
 
 
216 aa  98.2  8e-20  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_2790  HAD family hydrolase  30.43 
 
 
223 aa  98.2  8e-20  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
CP001509  ECD_01696  predicted hydrolase  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
CP001637  EcDH1_1915  HAD-superfamily hydrolase, subfamily IA, variant 3  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli DH1  Bacteria  normal  0.752357  n/a   
 
 
-
 
NC_010468  EcolC_1905  2-deoxyglucose-6-phosphatase  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli ATCC 8739  Bacteria  normal  0.798501  normal  0.727123 
 
 
-
 
NC_012892  B21_01684  hypothetical protein  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_1947  2-deoxyglucose-6-phosphatase  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli E24377A  Bacteria  normal  0.504113  n/a   
 
 
-
 
NC_010498  EcSMS35_1464  2-deoxyglucose-6-phosphatase  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli SMS-3-5  Bacteria  normal  normal 
 
 
-
 
NC_009800  EcHS_A1808  2-deoxyglucose-6-phosphatase  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli HS  Bacteria  normal  0.305682  n/a   
 
 
-
 
NC_011353  ECH74115_2445  2-deoxyglucose-6-phosphatase  34.04 
 
 
222 aa  98.2  9e-20  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1517  HAD family hydrolase  31.46 
 
 
216 aa  98.2  9e-20  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010658  SbBS512_E1972  2-deoxyglucose-6-phosphatase  34.04 
 
 
222 aa  98.2  9e-20  Shigella boydii CDC 3083-94  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0452  HAD family hydrolase  31.08 
 
 
221 aa  97.8  1e-19  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_013159  Svir_39300  haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED  35.05 
 
 
218 aa  97.8  1e-19  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_009665  Shew185_3926  2-deoxyglucose-6-phosphatase  33.16 
 
 
219 aa  97.4  1e-19  Shewanella baltica OS185  Bacteria  hitchhiker  0.00000000238408  n/a   
 
 
-
 
NC_010581  Bind_0935  HAD family hydrolase  33.85 
 
 
235 aa  97.4  1e-19  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.941543  normal 
 
 
-
 
NC_009436  Ent638_1717  2-deoxyglucose-6-phosphatase  34.92 
 
 
223 aa  97.1  2e-19  Enterobacter sp. 638  Bacteria  normal  normal  0.886251 
 
 
-
 
NC_013457  VEA_000391  2-deoxyglucose-6-phosphate hydrolase YniC  32.09 
 
 
218 aa  97.1  2e-19  Vibrio sp. Ex25  Bacteria  normal  0.0106831  n/a   
 
 
-
 
NC_011772  BCG9842_B0922  hydrolase, haloacid dehalogenase-like family  31.63 
 
 
235 aa  96.7  2e-19  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_010803  Clim_0139  HAD-superfamily hydrolase, subfamily IA, variant 3  35.08 
 
 
220 aa  96.7  2e-19  Chlorobium limicola DSM 245  Bacteria  hitchhiker  0.000437323  n/a   
 
 
-
 
NC_007958  RPD_3933  HAD family hydrolase  32.98 
 
 
271 aa  97.1  2e-19  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal 
 
 
-
 
NC_010338  Caul_0320  HAD family hydrolase  36.84 
 
 
241 aa  96.7  2e-19  Caulobacter sp. K31  Bacteria  normal  0.288784  normal 
 
 
-
 
NC_009052  Sbal_3906  2-deoxyglucose-6-phosphatase  33.16 
 
 
219 aa  97.1  2e-19  Shewanella baltica OS155  Bacteria  unclonable  0.000000000443869  n/a   
 
 
-
 
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