More than 300 homologs were found in PanDaTox collection
for query gene Pecwa_4555 on replicon NC_013421
Organism: Pectobacterium wasabiae WPP163



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013421  Pecwa_4555  binding-protein-dependent transport systems inner membrane component  100 
 
 
226 aa  446  1.0000000000000001e-124  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_0503  ABC transporter  59.11 
 
 
225 aa  235  4e-61  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_26240  ABC-type proline/glycine betaine transport system, permease component  54.95 
 
 
230 aa  206  2e-52  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.408698  normal  0.833764 
 
 
-
 
NC_013510  Tcur_3634  binding-protein-dependent transport systems inner membrane component  46.49 
 
 
229 aa  193  1e-48  Thermomonospora curvata DSM 43183  Bacteria  normal  0.737383  n/a   
 
 
-
 
NC_013595  Sros_8179  proline/glycine betaine ABC transporter  44.14 
 
 
223 aa  179  2.9999999999999997e-44  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013235  Namu_1404  binding-protein-dependent transport systems inner membrane component  51.57 
 
 
258 aa  169  3e-41  Nakamurella multipartita DSM 44233  Bacteria  normal  normal  0.848892 
 
 
-
 
NC_009664  Krad_1292  binding-protein-dependent transport systems inner membrane component  50 
 
 
251 aa  168  8e-41  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_2555  binding-protein-dependent transport systems inner membrane component  40.81 
 
 
248 aa  161  7e-39  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.0000000304534 
 
 
-
 
NC_013131  Caci_3085  binding-protein-dependent transport systems inner membrane component  41.44 
 
 
225 aa  159  3e-38  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.416296  normal  0.12861 
 
 
-
 
NC_008541  Arth_2840  binding-protein-dependent transport systems inner membrane component  42.44 
 
 
248 aa  157  2e-37  Arthrobacter sp. FB24  Bacteria  decreased coverage  0.00306406  n/a   
 
 
-
 
NC_014210  Ndas_0399  binding-protein-dependent transport systems inner membrane component  43.36 
 
 
225 aa  152  5e-36  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013172  Bfae_30020  ABC-type proline/glycine betaine transport system, permease component  40.83 
 
 
223 aa  142  4e-33  Brachybacterium faecium DSM 4810  Bacteria  normal  0.115362  n/a   
 
 
-
 
NC_013093  Amir_6269  binding-protein-dependent transport systems inner membrane component  43.3 
 
 
243 aa  141  7e-33  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009077  Mjls_5345  binding-protein-dependent transport systems inner membrane component  42.79 
 
 
264 aa  134  9.999999999999999e-31  Mycobacterium sp. JLS  Bacteria  normal  0.214986  normal 
 
 
-
 
NC_008146  Mmcs_4964  binding-protein-dependent transport systems inner membrane component  42.79 
 
 
264 aa  134  9.999999999999999e-31  Mycobacterium sp. MCS  Bacteria  normal  0.517846  n/a   
 
 
-
 
NC_008705  Mkms_5052  binding-protein-dependent transport systems inner membrane component  42.79 
 
 
264 aa  134  9.999999999999999e-31  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_13788  osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport system permease protein proZ  41.89 
 
 
239 aa  132  3e-30  Mycobacterium tuberculosis F11  Bacteria  normal  normal  0.991425 
 
 
-
 
NC_009338  Mflv_1210  binding-protein-dependent transport systems inner membrane component  40.21 
 
 
257 aa  125  5e-28  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_5598  binding-protein-dependent transport systems inner membrane component  41.97 
 
 
264 aa  124  1e-27  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_2260  binding-protein-dependent transport systems inner membrane component  39.22 
 
 
227 aa  120  1.9999999999999998e-26  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.360102 
 
 
-
 
NC_008254  Meso_2980  binding-protein-dependent transport systems inner membrane component  38.17 
 
 
211 aa  117  9.999999999999999e-26  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0746  substrate-binding region of ABC-type glycine betaine transport system  38.79 
 
 
504 aa  115  5e-25  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_0763  substrate-binding region of ABC-type glycine betaine transport system  38.79 
 
 
504 aa  115  5e-25  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.458546  n/a   
 
 
-
 
NC_002976  SERP0386  ABC transporter, permease protein  39.05 
 
 
504 aa  114  8.999999999999998e-25  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_37580  ABC-type proline/glycine betaine transport system, permease component  35.51 
 
 
228 aa  114  1.0000000000000001e-24  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_013517  Sterm_3032  Substrate-binding region of ABC-type glycine betaine transport system  32.29 
 
 
531 aa  113  3e-24  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.367999  n/a   
 
 
-
 
NC_013947  Snas_1035  binding-protein-dependent transport systems inner membrane component  36.28 
 
 
236 aa  113  3e-24  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.163683 
 
 
-
 
NC_009972  Haur_0349  binding-protein-dependent transport systems inner membrane component  36.61 
 
 
217 aa  111  8.000000000000001e-24  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.0000441273  n/a   
 
 
-
 
NC_013037  Dfer_1250  binding-protein-dependent transport systems inner membrane component  38.6 
 
 
525 aa  111  1.0000000000000001e-23  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.615651  normal  0.522042 
 
 
-
 
NC_013730  Slin_0317  binding-protein-dependent transport systems inner membrane component  35.92 
 
 
519 aa  110  2.0000000000000002e-23  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.417886 
 
 
-
 
NC_010320  Teth514_1202  binding-protein-dependent transport systems inner membrane component  33.79 
 
 
212 aa  109  3e-23  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_014151  Cfla_1339  binding-protein-dependent transport systems inner membrane component  35.19 
 
 
255 aa  109  4.0000000000000004e-23  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.889629  hitchhiker  0.000819014 
 
 
-
 
NC_012669  Bcav_2670  binding-protein-dependent transport systems inner membrane component  34.11 
 
 
230 aa  108  7.000000000000001e-23  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.538253  normal  0.0824918 
 
 
-
 
NC_009523  RoseRS_1817  binding-protein-dependent transport systems inner membrane component  39.53 
 
 
217 aa  107  1e-22  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.0299279 
 
 
-
 
NC_009380  Strop_4289  binding-protein-dependent transport systems inner membrane component  35.51 
 
 
244 aa  107  1e-22  Salinispora tropica CNB-440  Bacteria  normal  0.729168  normal  0.839045 
 
 
-
 
NC_013204  Elen_0084  Substrate-binding region of ABC-type glycine betaine transport system  33.81 
 
 
528 aa  108  1e-22  Eggerthella lenta DSM 2243  Bacteria  normal  0.689632  normal 
 
 
-
 
NC_013411  GYMC61_1174  binding-protein-dependent transport systems inner membrane component  34.52 
 
 
209 aa  107  2e-22  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_010003  Pmob_1127  binding-protein-dependent transport systems inner membrane component  31.86 
 
 
216 aa  106  2e-22  Petrotoga mobilis SJ95  Bacteria  normal  0.721959  n/a   
 
 
-
 
NC_008148  Rxyl_0983  binding-protein-dependent transport systems inner membrane component  34.93 
 
 
217 aa  106  3e-22  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.762927  n/a   
 
 
-
 
NC_013517  Sterm_1515  Substrate-binding region of ABC-type glycine betaine transport system  33.33 
 
 
526 aa  106  3e-22  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.0692577  n/a   
 
 
-
 
NC_008261  CPF_0538  glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein  33.81 
 
 
517 aa  105  5e-22  Clostridium perfringens ATCC 13124  Bacteria  normal  0.863672  n/a   
 
 
-
 
NC_008262  CPR_0522  glycine betaine/carnitine/choline ABC transporter, permease/substrate-binding protein  34.6 
 
 
517 aa  105  5e-22  Clostridium perfringens SM101  Bacteria  normal  0.271995  n/a   
 
 
-
 
NC_011898  Ccel_3333  Substrate-binding region of ABC-type glycine betaine transport system  31.6 
 
 
524 aa  105  5e-22  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000937167  n/a   
 
 
-
 
NC_009621  Smed_5106  binding-protein-dependent transport systems inner membrane component  31.37 
 
 
220 aa  105  6e-22  Sinorhizobium medicae WSM419  Bacteria  normal  0.485727  normal  0.10095 
 
 
-
 
NC_004116  SAG0243  amino acid ABC transporter, permease protein  30.5 
 
 
211 aa  103  1e-21  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_2528  binding-protein-dependent transport systems inner membrane component  39.18 
 
 
217 aa  104  1e-21  Roseiflexus castenholzii DSM 13941  Bacteria  normal  hitchhiker  0.00802547 
 
 
-
 
NC_010001  Cphy_0119  substrate-binding region of ABC-type glycine betaine transport system  32.04 
 
 
523 aa  103  3e-21  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.000124345  n/a   
 
 
-
 
NC_002976  SERP2357  amino acid ABC transporter, permease protein  32.99 
 
 
211 aa  102  3e-21  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_0296  binding-protein-dependent transport systems inner membrane component  34.17 
 
 
211 aa  102  3e-21  Geobacillus sp. WCH70  Bacteria  normal  0.4946  n/a   
 
 
-
 
NC_013132  Cpin_4963  binding-protein-dependent transport systems inner membrane component  39.89 
 
 
522 aa  103  3e-21  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.0875398  normal  0.252786 
 
 
-
 
NC_007973  Rmet_1598  substrate-binding region of ABC-type glycine betaine transport system  34.03 
 
 
516 aa  102  4e-21  Cupriavidus metallidurans CH34  Bacteria  normal  0.144217  normal 
 
 
-
 
NC_008148  Rxyl_0579  binding-protein-dependent transport systems inner membrane component  34.95 
 
 
217 aa  102  6e-21  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.584474  n/a   
 
 
-
 
NC_002976  SERP2030  amino acid ABC transporter, permease protein  30.81 
 
 
211 aa  101  8e-21  Staphylococcus epidermidis RP62A  Bacteria  normal  0.207242  n/a   
 
 
-
 
NC_013457  VEA_001529  probable inner-membrane permease  31.16 
 
 
199 aa  101  9e-21  Vibrio sp. Ex25  Bacteria  normal  0.90895  n/a   
 
 
-
 
NC_007963  Csal_2944  binding-protein-dependent transport systems inner membrane component  33.84 
 
 
400 aa  101  9e-21  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.543286  n/a   
 
 
-
 
NC_009767  Rcas_2531  binding-protein-dependent transport systems inner membrane component  37.99 
 
 
213 aa  100  1e-20  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.41546  hitchhiker  0.00151664 
 
 
-
 
NC_008699  Noca_0454  binding-protein-dependent transport systems inner membrane component  42.16 
 
 
257 aa  101  1e-20  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_009953  Sare_4724  binding-protein-dependent transport systems inner membrane component  33.97 
 
 
244 aa  100  2e-20  Salinispora arenicola CNS-205  Bacteria  normal  decreased coverage  0.0000283909 
 
 
-
 
NC_009513  Lreu_0185  binding-protein-dependent transport systems inner membrane component  35.64 
 
 
221 aa  99  5e-20  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0984  binding-protein-dependent transport systems inner membrane component  36.11 
 
 
236 aa  99  5e-20  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.660466  n/a   
 
 
-
 
NC_010184  BcerKBAB4_2100  substrate-binding region of ABC-type glycine betaine transport system  39.11 
 
 
503 aa  99  5e-20  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0700074  n/a   
 
 
-
 
NC_007948  Bpro_1156  binding-protein-dependent transport systems inner membrane component  33.66 
 
 
207 aa  98.6  6e-20  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_0578  binding-protein-dependent transport systems inner membrane component  37.16 
 
 
235 aa  99  6e-20  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.0139749  n/a   
 
 
-
 
NC_013739  Cwoe_3263  binding-protein-dependent transport systems inner membrane component  35.03 
 
 
229 aa  99  6e-20  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.0142604 
 
 
-
 
NC_009972  Haur_0352  binding-protein-dependent transport systems inner membrane component  34.43 
 
 
212 aa  98.6  8e-20  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.00133912  n/a   
 
 
-
 
NC_011725  BCB4264_A2263  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  40.54 
 
 
503 aa  97.8  1e-19  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_010159  YpAngola_A1330  quaternary amine ABC transporter permease  32.7 
 
 
384 aa  97.8  1e-19  Yersinia pestis Angola  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B3062  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  40.54 
 
 
503 aa  97.4  1e-19  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_005945  BAS2126  glycine betaine/L-proline ABC transporter permease  38.61 
 
 
503 aa  97.4  1e-19  Bacillus anthracis str. Sterne  Bacteria  normal  0.887969  n/a   
 
 
-
 
NC_005957  BT9727_2064  glycine betaine/choline ABC transporter, ATP-binding protein  38.61 
 
 
503 aa  97.4  1e-19  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.508054  n/a   
 
 
-
 
NC_006274  BCZK2060  glycine betaine/choline ABC transporter, ATP-binding protein  38.61 
 
 
503 aa  97.4  1e-19  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_2280  glycine betaine/L-proline ABC transporter permease protein  38.61 
 
 
503 aa  97.4  1e-19  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.578491  n/a   
 
 
-
 
NC_010465  YPK_2864  binding-protein-dependent transport systems inner membrane component  32.7 
 
 
384 aa  97.8  1e-19  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_2306  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  38.61 
 
 
503 aa  97.4  1e-19  Bacillus cereus AH820  Bacteria  n/a    normal  0.816481 
 
 
-
 
NC_009708  YpsIP31758_2785  quaternary amine ABC transporter permease  32.7 
 
 
384 aa  97.8  1e-19  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A2390  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  38.61 
 
 
503 aa  97.8  1e-19  Bacillus cereus AH187  Bacteria  normal  0.114171  n/a   
 
 
-
 
NC_013757  Gobs_0624  binding-protein-dependent transport systems inner membrane component  34.41 
 
 
243 aa  97.4  2e-19  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_2474  binding-protein-dependent transport systems inner membrane component  29.8 
 
 
211 aa  97.4  2e-19  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.13842  n/a   
 
 
-
 
NC_009632  SaurJH1_2522  binding-protein-dependent transport systems inner membrane component  29.8 
 
 
211 aa  97.4  2e-19  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.241712  n/a   
 
 
-
 
NC_009523  RoseRS_1814  binding-protein-dependent transport systems inner membrane component  35.68 
 
 
213 aa  96.7  3e-19  Roseiflexus sp. RS-1  Bacteria  normal  0.518824  normal  0.0107204 
 
 
-
 
NC_003909  BCE_2314  glycine betaine/L-proline ABC transporter, permease protein, putative  38.61 
 
 
503 aa  95.9  5e-19  Bacillus cereus ATCC 10987  Bacteria  normal  0.0653078  n/a   
 
 
-
 
NC_008347  Mmar10_1070  substrate-binding region of ABC-type glycine betaine transport system  31.89 
 
 
525 aa  95.1  7e-19  Maricaulis maris MCS10  Bacteria  normal  0.019749  normal 
 
 
-
 
NC_011884  Cyan7425_4031  binding-protein-dependent transport systems inner membrane component  35.64 
 
 
205 aa  95.1  7e-19  Cyanothece sp. PCC 7425  Bacteria  normal  hitchhiker  0.00343198 
 
 
-
 
NC_007948  Bpro_1155  binding-protein-dependent transport systems inner membrane component  35.58 
 
 
213 aa  94.7  9e-19  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_008752  Aave_1496  binding-protein-dependent transport systems inner membrane component  31.69 
 
 
451 aa  94.7  9e-19  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0787924  normal  0.370511 
 
 
-
 
NC_010003  Pmob_1125  binding-protein-dependent transport systems inner membrane component  28.8 
 
 
218 aa  94  2e-18  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_007347  Reut_A2494  binding-protein dependent transport system inner membrane protein  29.95 
 
 
216 aa  94  2e-18  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_009832  Spro_1448  binding-protein-dependent transport systems inner membrane component  35.1 
 
 
260 aa  94  2e-18  Serratia proteamaculans 568  Bacteria  normal  0.320512  normal 
 
 
-
 
NC_012803  Mlut_15730  ABC-type proline/glycine betaine transport system, permease component  35.68 
 
 
251 aa  94  2e-18  Micrococcus luteus NCTC 2665  Bacteria  normal  n/a   
 
 
-
 
NC_011992  Dtpsy_0980  binding-protein-dependent transport systems inner membrane component  30.96 
 
 
400 aa  94  2e-18  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_1064  binding-protein-dependent transport systems inner membrane component  30.96 
 
 
400 aa  93.6  2e-18  Acidovorax sp. JS42  Bacteria  normal  0.0842907  normal 
 
 
-
 
NC_010682  Rpic_2784  Substrate-binding region of ABC-type glycine betaine transport system  33.67 
 
 
504 aa  93.2  3e-18  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_009436  Ent638_2729  binding-protein-dependent transport systems inner membrane component  33.82 
 
 
385 aa  93.2  3e-18  Enterobacter sp. 638  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_2946  binding-protein-dependent transport systems inner membrane component  34.3 
 
 
255 aa  92.8  3e-18  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.0159646  n/a   
 
 
-
 
NC_008527  LACR_0914  choline ABC transporter permease and substrate binding protein  30.26 
 
 
500 aa  92.8  4e-18  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  0.222381  n/a   
 
 
-
 
NC_009832  Spro_1446  binding-protein-dependent transport systems inner membrane component  31.63 
 
 
386 aa  92  7e-18  Serratia proteamaculans 568  Bacteria  normal  0.706116  normal 
 
 
-
 
NC_007963  Csal_2355  binding-protein-dependent transport systems inner membrane component  30.92 
 
 
243 aa  92  7e-18  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_012856  Rpic12D_2379  Substrate-binding region of ABC-type glycine betaine transport system  33.16 
 
 
518 aa  91.7  8e-18  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_008531  LEUM_1017  ABC-type proline/glycine betaine transport systems, permease and substrate binding protein  36.36 
 
 
508 aa  91.7  8e-18  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  unclonable  0.00355742  n/a   
 
 
-
 
NC_010002  Daci_2667  binding-protein-dependent transport systems inner membrane component  29.44 
 
 
399 aa  91.7  9e-18  Delftia acidovorans SPH-1  Bacteria  decreased coverage  0.00496589  normal 
 
 
-
 
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