More than 300 homologs were found in PanDaTox collection
for query gene Cthe_0537 on replicon NC_009012
Organism: Clostridium thermocellum ATCC 27405



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009012  Cthe_0537  two component transcriptional regulator  100 
 
 
223 aa  445  1.0000000000000001e-124  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.340982  n/a   
 
 
-
 
NC_010001  Cphy_2076  two component transcriptional regulator  65.92 
 
 
223 aa  308  5.9999999999999995e-83  Clostridium phytofermentans ISDg  Bacteria  normal  0.0826632  n/a   
 
 
-
 
NC_013204  Elen_1538  two component transcriptional regulator, winged helix family  51.58 
 
 
223 aa  244  6e-64  Eggerthella lenta DSM 2243  Bacteria  normal  0.705917  normal  0.0786085 
 
 
-
 
NC_013947  Snas_0580  two component transcriptional regulator, winged helix family  43.56 
 
 
226 aa  190  2e-47  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  44.44 
 
 
229 aa  189  2e-47  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  44 
 
 
229 aa  187  1e-46  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  42.22 
 
 
226 aa  187  2e-46  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_008699  Noca_4046  response regulator receiver  43.3 
 
 
225 aa  186  2e-46  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  43.56 
 
 
231 aa  184  8e-46  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_0850  two component transcriptional regulator, winged helix family  41.78 
 
 
226 aa  182  2.0000000000000003e-45  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  44 
 
 
226 aa  182  4.0000000000000006e-45  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_013093  Amir_6749  two component transcriptional regulator, winged helix family  42.67 
 
 
226 aa  182  4.0000000000000006e-45  Actinosynnema mirum DSM 43827  Bacteria  normal  0.290774  n/a   
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  43.56 
 
 
230 aa  181  8.000000000000001e-45  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_0724  two component transcriptional regulator  41.78 
 
 
226 aa  180  2e-44  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  41.07 
 
 
228 aa  178  4.999999999999999e-44  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  42.67 
 
 
226 aa  178  4.999999999999999e-44  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013441  Gbro_0997  response regulator receiver  41.23 
 
 
228 aa  178  5.999999999999999e-44  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4602  two component transcriptional regulator, winged helix family  41.15 
 
 
226 aa  177  1e-43  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1153  two component transcriptional regulator, winged helix family  42.73 
 
 
224 aa  176  2e-43  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_6145  two component transcriptional regulator  42.15 
 
 
228 aa  177  2e-43  Frankia sp. EAN1pec  Bacteria  normal  normal  0.788201 
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  40.35 
 
 
229 aa  176  3e-43  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_009338  Mflv_0082  two component transcriptional regulator  40.79 
 
 
228 aa  175  4e-43  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_10499  two component system sensor transduction protein regX3  40.97 
 
 
227 aa  174  8e-43  Mycobacterium tuberculosis F11  Bacteria  decreased coverage  2.46064e-66  normal 
 
 
-
 
NC_008146  Mmcs_0661  two component transcriptional regulator  40.79 
 
 
228 aa  174  8e-43  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_0674  two component transcriptional regulator  40.79 
 
 
228 aa  174  8e-43  Mycobacterium sp. KMS  Bacteria  normal  normal  0.850641 
 
 
-
 
NC_009077  Mjls_0654  two component transcriptional regulator  40.79 
 
 
228 aa  174  8e-43  Mycobacterium sp. JLS  Bacteria  normal  normal  0.682961 
 
 
-
 
NC_014248  Aazo_0581  winged helix family two component transcriptional regulator  41.78 
 
 
242 aa  174  9.999999999999999e-43  'Nostoc azollae' 0708  Bacteria  normal  0.296955  n/a   
 
 
-
 
NC_008726  Mvan_0831  two component transcriptional regulator  40.35 
 
 
228 aa  173  1.9999999999999998e-42  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.310785  normal 
 
 
-
 
NC_013174  Jden_2083  two component transcriptional regulator, winged helix family  40.93 
 
 
237 aa  172  2.9999999999999996e-42  Jonesia denitrificans DSM 20603  Bacteria  normal  0.873655  normal 
 
 
-
 
NC_007413  Ava_1878  two component transcriptional regulator  41.33 
 
 
242 aa  172  2.9999999999999996e-42  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.559477 
 
 
-
 
NC_013172  Bfae_09290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  41.59 
 
 
229 aa  172  3.9999999999999995e-42  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_014158  Tpau_0654  two component transcriptional regulator, winged helix family  41.48 
 
 
229 aa  172  3.9999999999999995e-42  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.200991  n/a   
 
 
-
 
NC_009953  Sare_0404  two component transcriptional regulator  40.71 
 
 
227 aa  171  5.999999999999999e-42  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00316128 
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  42.08 
 
 
230 aa  171  6.999999999999999e-42  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  40.35 
 
 
229 aa  171  6.999999999999999e-42  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_010816  BLD_1073  putative response regulator  40.26 
 
 
234 aa  171  1e-41  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_08590  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  38.74 
 
 
239 aa  169  2e-41  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.857083 
 
 
-
 
NC_009380  Strop_0337  two component transcriptional regulator  40.27 
 
 
227 aa  170  2e-41  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  37.87 
 
 
234 aa  170  2e-41  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_013235  Namu_4929  two component transcriptional regulator, winged helix family  40.27 
 
 
226 aa  169  3e-41  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_011898  Ccel_0559  two component transcriptional regulator, winged helix family  38.84 
 
 
228 aa  169  3e-41  Clostridium cellulolyticum H10  Bacteria  normal  0.276329  n/a   
 
 
-
 
NC_011661  Dtur_1237  two component transcriptional regulator, winged helix family  43.11 
 
 
232 aa  168  6e-41  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_4207  two component transcriptional regulator, winged helix family  40.44 
 
 
247 aa  167  1e-40  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_011726  PCC8801_2302  two component transcriptional regulator, winged helix family  40.89 
 
 
243 aa  167  1e-40  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_009664  Krad_0896  two component transcriptional regulator, winged helix family  43.11 
 
 
226 aa  167  1e-40  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.232326  hitchhiker  0.00518822 
 
 
-
 
NC_013161  Cyan8802_2353  two component transcriptional regulator, winged helix family  40.89 
 
 
243 aa  167  1e-40  Cyanothece sp. PCC 8802  Bacteria  normal  0.0794558  normal 
 
 
-
 
NC_006274  BCZK1018  response regulator  37.44 
 
 
234 aa  166  2e-40  Bacillus cereus E33L  Bacteria  normal  0.54503  n/a   
 
 
-
 
NC_007335  PMN2A_0436  two component transcriptional regulator  42.31 
 
 
245 aa  166  2e-40  Prochlorococcus marinus str. NATL2A  Bacteria  normal  0.18923  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  39.38 
 
 
236 aa  166  2e-40  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_005945  BAS1040  DNA-binding response regulator  37.44 
 
 
234 aa  166  2.9999999999999998e-40  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_1119  DNA-binding response regulator  37.44 
 
 
234 aa  166  2.9999999999999998e-40  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_1017  response regulator  37.44 
 
 
234 aa  165  4e-40  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.0627963  n/a   
 
 
-
 
NC_011658  BCAH187_A1275  DNA-binding response regulator  37.44 
 
 
234 aa  165  4e-40  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1198  DNA-binding response regulator  37.44 
 
 
234 aa  165  4e-40  Bacillus cereus AH820  Bacteria  n/a    normal  0.885409 
 
 
-
 
NC_008578  Acel_1832  two component transcriptional regulator  38.5 
 
 
245 aa  166  4e-40  Acidothermus cellulolyticus 11B  Bacteria  normal  0.366424  normal  0.561636 
 
 
-
 
NC_007777  Francci3_0471  two component transcriptional regulator  42.22 
 
 
226 aa  164  6.9999999999999995e-40  Frankia sp. CcI3  Bacteria  normal  normal  0.734397 
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  38.46 
 
 
228 aa  164  6.9999999999999995e-40  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008312  Tery_0954  two component transcriptional regulator  40 
 
 
243 aa  164  6.9999999999999995e-40  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.0817018 
 
 
-
 
NC_003909  BCE_1218  DNA-binding response regulator  37.44 
 
 
234 aa  164  1.0000000000000001e-39  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0249  two component transcriptional regulator  36.44 
 
 
233 aa  164  1.0000000000000001e-39  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0382139  n/a   
 
 
-
 
NC_013093  Amir_6310  two component transcriptional regulator, winged helix family  37.84 
 
 
261 aa  164  1.0000000000000001e-39  Actinosynnema mirum DSM 43827  Bacteria  normal  0.534044  n/a   
 
 
-
 
NC_011772  BCG9842_B4168  DNA-binding response regulator  37.33 
 
 
234 aa  164  1.0000000000000001e-39  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A1173  DNA-binding response regulator  37.44 
 
 
234 aa  164  1.0000000000000001e-39  Bacillus cereus B4264  Bacteria  normal  0.423617  n/a   
 
 
-
 
NC_008819  NATL1_11471  two-component response regulator, phosphate  42.31 
 
 
245 aa  164  1.0000000000000001e-39  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal  0.0202491 
 
 
-
 
NC_005957  BT9727_0923  two-component response regulator; MrsR2 protein  38.22 
 
 
240 aa  163  2.0000000000000002e-39  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.227452  n/a   
 
 
-
 
NC_006274  BCZK0906  response regulator  38.22 
 
 
240 aa  163  2.0000000000000002e-39  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_1453  two component transcriptional regulator  39.56 
 
 
244 aa  163  2.0000000000000002e-39  Synechococcus elongatus PCC 7942  Bacteria  normal  0.952418  normal  0.0249242 
 
 
-
 
NC_010184  BcerKBAB4_2313  two component transcriptional regulator  38.05 
 
 
228 aa  163  2.0000000000000002e-39  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0313786  n/a   
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  39.74 
 
 
235 aa  163  2.0000000000000002e-39  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  39.74 
 
 
235 aa  162  3e-39  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_005957  BT9727_0242  response regulator  37.44 
 
 
233 aa  162  3e-39  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  39.74 
 
 
235 aa  162  3e-39  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_011773  BCAH820_0296  DNA-binding response regulator  37.44 
 
 
233 aa  162  3e-39  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_010184  BcerKBAB4_1023  two component transcriptional regulator  37.61 
 
 
233 aa  162  3e-39  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A0322  DNA-binding response regulator  37.44 
 
 
233 aa  162  4.0000000000000004e-39  Bacillus cereus AH187  Bacteria  hitchhiker  0.000000418869  n/a   
 
 
-
 
NC_011772  BCG9842_B2021  regulatory protein VanR  37.17 
 
 
228 aa  162  4.0000000000000004e-39  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_0978  two component transcriptional regulator  38.57 
 
 
321 aa  162  4.0000000000000004e-39  Frankia sp. CcI3  Bacteria  normal  0.323902  normal 
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  39.74 
 
 
235 aa  162  5.0000000000000005e-39  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  39.74 
 
 
235 aa  162  5.0000000000000005e-39  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS0256  DNA-binding response regulator  37.44 
 
 
233 aa  162  5.0000000000000005e-39  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  39.74 
 
 
235 aa  162  5.0000000000000005e-39  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_005957  BT9727_5147  response regulator  39.74 
 
 
235 aa  162  5.0000000000000005e-39  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_006274  BCZK0245  response regulator  37.44 
 
 
233 aa  162  5.0000000000000005e-39  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  39.74 
 
 
235 aa  162  5.0000000000000005e-39  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_007530  GBAA_0271  DNA-binding response regulator  37.44 
 
 
233 aa  162  5.0000000000000005e-39  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.439326  n/a   
 
 
-
 
NC_011725  BCB4264_A0303  DNA-binding response regulator  37.44 
 
 
233 aa  162  5.0000000000000005e-39  Bacillus cereus B4264  Bacteria  normal  0.0610099  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  39.74 
 
 
235 aa  162  5.0000000000000005e-39  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  39.74 
 
 
235 aa  162  5.0000000000000005e-39  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_011772  BCG9842_B5021  DNA-binding response regulator  37 
 
 
233 aa  161  6e-39  Bacillus cereus G9842  Bacteria  normal  0.0330449  normal 
 
 
-
 
NC_011884  Cyan7425_1115  two component transcriptional regulator, winged helix family  38.67 
 
 
243 aa  162  6e-39  Cyanothece sp. PCC 7425  Bacteria  normal  0.0950226  normal 
 
 
-
 
NC_013216  Dtox_1554  two component transcriptional regulator, winged helix family  37.33 
 
 
229 aa  161  6e-39  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  hitchhiker  0.00709514 
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  38.43 
 
 
236 aa  161  6e-39  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  39.48 
 
 
239 aa  161  7e-39  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_013124  Afer_0200  two component transcriptional regulator, winged helix family  40.18 
 
 
242 aa  161  8.000000000000001e-39  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.0955644  n/a   
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  39.3 
 
 
235 aa  161  8.000000000000001e-39  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_011899  Hore_04710  two component transcriptional regulator, winged helix family  37 
 
 
237 aa  161  8.000000000000001e-39  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_2351  two component transcriptional regulator, winged helix family  37.84 
 
 
231 aa  161  8.000000000000001e-39  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.274912  n/a   
 
 
-
 
NC_013131  Caci_0793  two component transcriptional regulator, winged helix family  39.01 
 
 
225 aa  161  9e-39  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_011892  Mnod_8578  two component transcriptional regulator, winged helix family  37.1 
 
 
231 aa  160  1e-38  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.0565107  n/a   
 
 
-
 
NC_014151  Cfla_0657  two component transcriptional regulator, winged helix family  40.77 
 
 
235 aa  160  1e-38  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.118815  hitchhiker  0.000311431 
 
 
-
 
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