More than 300 homologs were found in PanDaTox collection
for query gene Bcav_0571 on replicon NC_012669
Organism: Beutenbergia cavernae DSM 12333



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_012669  Bcav_0571  binding-protein-dependent transport systems inner membrane component  100 
 
 
296 aa  575  1.0000000000000001e-163  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_2623  binding-protein-dependent transport systems inner membrane component  35.86 
 
 
330 aa  157  2e-37  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0584633  normal 
 
 
-
 
NC_009338  Mflv_3776  binding-protein-dependent transport systems inner membrane component  34.15 
 
 
286 aa  156  4e-37  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.771132  normal  0.363599 
 
 
-
 
NC_010159  YpAngola_A2083  carbohydrate ABC transporter permease  35.94 
 
 
286 aa  154  2e-36  Yersinia pestis Angola  Bacteria  normal  normal  0.0183943 
 
 
-
 
NC_008699  Noca_0870  binding-protein-dependent transport systems inner membrane component  35.58 
 
 
309 aa  153  2.9999999999999998e-36  Nocardioides sp. JS614  Bacteria  normal  0.800905  n/a   
 
 
-
 
NC_010465  YPK_2279  binding-protein-dependent transport systems inner membrane component  35.94 
 
 
286 aa  152  5e-36  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_1880  binding-protein-dependent transport systems inner membrane component  37.08 
 
 
286 aa  152  5.9999999999999996e-36  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.262739  normal  0.333569 
 
 
-
 
NC_009708  YpsIP31758_2171  carbohydrate ABC transporter permease  35.38 
 
 
280 aa  152  7e-36  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  0.0580768  n/a   
 
 
-
 
NC_007643  Rru_A1261  binding-protein dependent transport system inner membrane protein  32.76 
 
 
298 aa  152  8e-36  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.196832  n/a   
 
 
-
 
NC_008686  Pden_1048  binding-protein-dependent transport systems inner membrane component  30.43 
 
 
308 aa  151  1e-35  Paracoccus denitrificans PD1222  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_5739  ABC transporter permease  32.5 
 
 
318 aa  151  1e-35  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.184804 
 
 
-
 
NC_009667  Oant_0362  binding-protein-dependent transport systems inner membrane component  29.35 
 
 
312 aa  150  3e-35  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.541424  n/a   
 
 
-
 
NC_012848  Rleg_5199  binding-protein-dependent transport systems inner membrane component  30.6 
 
 
312 aa  149  4e-35  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.0867066 
 
 
-
 
NC_013411  GYMC61_2958  binding-protein-dependent transport systems inner membrane component  35.78 
 
 
435 aa  149  4e-35  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_008726  Mvan_2623  binding-protein-dependent transport systems inner membrane component  34.15 
 
 
287 aa  149  6e-35  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_0396  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
307 aa  148  8e-35  Thermoanaerobacter sp. X514  Bacteria  normal  0.701562  n/a   
 
 
-
 
NC_011368  Rleg2_5469  binding-protein-dependent transport systems inner membrane component  30.6 
 
 
313 aa  148  1.0000000000000001e-34  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.394829 
 
 
-
 
NC_012034  Athe_2309  binding-protein-dependent transport systems inner membrane component  31.3 
 
 
427 aa  147  2.0000000000000003e-34  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.00000129291  n/a   
 
 
-
 
NC_012669  Bcav_3713  binding-protein-dependent transport systems inner membrane component  35.84 
 
 
297 aa  147  3e-34  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal  0.174244 
 
 
-
 
NC_009636  Smed_2455  binding-protein-dependent transport systems inner membrane component  31.3 
 
 
313 aa  146  5e-34  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_012850  Rleg_2284  binding-protein-dependent transport systems inner membrane component  31.67 
 
 
291 aa  145  8.000000000000001e-34  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.257134 
 
 
-
 
NC_008699  Noca_3682  binding-protein-dependent transport systems inner membrane component  36.21 
 
 
283 aa  145  9e-34  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_008146  Mmcs_2419  binding-protein-dependent transport systems inner membrane component  34.15 
 
 
286 aa  145  1e-33  Mycobacterium sp. MCS  Bacteria  normal  0.235933  n/a   
 
 
-
 
NC_008705  Mkms_2464  binding-protein-dependent transport systems inner membrane component  34.15 
 
 
286 aa  145  1e-33  Mycobacterium sp. KMS  Bacteria  normal  0.80505  normal 
 
 
-
 
NC_009077  Mjls_2458  binding-protein-dependent transport systems inner membrane component  34.15 
 
 
286 aa  145  1e-33  Mycobacterium sp. JLS  Bacteria  normal  0.524108  normal 
 
 
-
 
NC_012034  Athe_0615  binding-protein-dependent transport systems inner membrane component  27.86 
 
 
296 aa  140  1.9999999999999998e-32  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009620  Smed_3811  binding-protein-dependent transport systems inner membrane component  31.45 
 
 
328 aa  141  1.9999999999999998e-32  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_2611  binding-protein-dependent transport systems inner membrane component  32.26 
 
 
280 aa  140  3.9999999999999997e-32  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_0803  binding-protein-dependent transport systems inner membrane component  31.79 
 
 
299 aa  139  4.999999999999999e-32  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.270687  normal 
 
 
-
 
NC_008541  Arth_3686  binding-protein-dependent transport systems inner membrane component  33.1 
 
 
310 aa  139  7e-32  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_009636  Smed_2698  binding-protein-dependent transport systems inner membrane component  32.25 
 
 
295 aa  138  8.999999999999999e-32  Sinorhizobium medicae WSM419  Bacteria  normal  0.0832027  normal 
 
 
-
 
NC_010003  Pmob_0306  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
294 aa  138  1e-31  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_014211  Ndas_4929  binding-protein-dependent transport systems inner membrane component  30.22 
 
 
311 aa  138  1e-31  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.155715  normal 
 
 
-
 
NC_012791  Vapar_3349  binding-protein-dependent transport systems inner membrane component  34.66 
 
 
291 aa  138  1e-31  Variovorax paradoxus S110  Bacteria  normal  0.230089  n/a   
 
 
-
 
NC_007484  Noc_0281  ABC transporter, inner membrane subunit  33.45 
 
 
292 aa  137  2e-31  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_012848  Rleg_4872  binding-protein-dependent transport systems inner membrane component  31.38 
 
 
310 aa  137  2e-31  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.181942  normal  0.51159 
 
 
-
 
NC_011729  PCC7424_1896  binding-protein-dependent transport systems inner membrane component  32.01 
 
 
296 aa  136  3.0000000000000003e-31  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  1.0543799999999999e-20 
 
 
-
 
NC_013205  Aaci_2236  binding-protein-dependent transport systems inner membrane component  31.52 
 
 
315 aa  137  3.0000000000000003e-31  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_0146  binding-protein-dependent transport systems inner membrane component  33.82 
 
 
292 aa  136  4e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0896196  normal 
 
 
-
 
NC_008786  Veis_2012  binding-protein-dependent transport systems inner membrane component  32.51 
 
 
310 aa  135  9.999999999999999e-31  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal  0.395958 
 
 
-
 
NC_009832  Spro_2296  binding-protein-dependent transport systems inner membrane component  39.08 
 
 
304 aa  134  9.999999999999999e-31  Serratia proteamaculans 568  Bacteria  normal  0.44429  normal 
 
 
-
 
NC_012669  Bcav_0828  binding-protein-dependent transport systems inner membrane component  32.13 
 
 
316 aa  134  1.9999999999999998e-30  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal  0.194369 
 
 
-
 
NC_013172  Bfae_01820  permease component of ABC-type sugar transporter  30.45 
 
 
312 aa  134  1.9999999999999998e-30  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_008010  Dgeo_2820  binding-protein-dependent transport systems inner membrane component  33.05 
 
 
305 aa  133  3.9999999999999996e-30  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
NC_009620  Smed_4915  binding-protein-dependent transport systems inner membrane component  30.33 
 
 
300 aa  133  3.9999999999999996e-30  Sinorhizobium medicae WSM419  Bacteria  normal  0.279079  normal  0.466467 
 
 
-
 
NC_013744  Htur_4398  binding-protein-dependent transport systems inner membrane component  29.93 
 
 
314 aa  132  5e-30  Haloterrigena turkmenica DSM 5511  Archaea  normal  0.0144983  n/a   
 
 
-
 
NC_009972  Haur_3640  binding-protein-dependent transport systems inner membrane component  30.32 
 
 
298 aa  132  9e-30  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_1681  binding-protein-dependent transport systems inner membrane component  30.99 
 
 
316 aa  131  1.0000000000000001e-29  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.130846  normal 
 
 
-
 
NC_014210  Ndas_3354  binding-protein-dependent transport systems inner membrane component  31.52 
 
 
299 aa  131  1.0000000000000001e-29  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_012850  Rleg_0286  binding-protein-dependent transport systems inner membrane component  31.37 
 
 
291 aa  130  2.0000000000000002e-29  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.231338  normal 
 
 
-
 
NC_009664  Krad_2091  binding-protein-dependent transport systems inner membrane component  32.06 
 
 
292 aa  130  2.0000000000000002e-29  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal 
 
 
-
 
NC_014213  Mesil_3227  extracellular solute-binding protein family 1  32.97 
 
 
307 aa  130  3e-29  Meiothermus silvanus DSM 9946  Bacteria  decreased coverage  0.00159401  normal  0.987884 
 
 
-
 
NC_007908  Rfer_0953  binding-protein-dependent transport systems inner membrane component  31.97 
 
 
292 aa  130  3e-29  Rhodoferax ferrireducens T118  Bacteria  normal  0.568052  n/a   
 
 
-
 
NC_014213  Mesil_3421  binding-protein-dependent transport systems inner membrane component  32.97 
 
 
307 aa  130  3e-29  Meiothermus silvanus DSM 9946  Bacteria  normal  0.556907  normal 
 
 
-
 
NC_009668  Oant_2941  binding-protein-dependent transport systems inner membrane component  28.87 
 
 
320 aa  130  3e-29  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.974377  n/a   
 
 
-
 
NC_013525  Tter_0830  binding-protein-dependent transport systems inner membrane component  29.24 
 
 
309 aa  129  4.0000000000000003e-29  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_013131  Caci_6903  binding-protein-dependent transport systems inner membrane component  32.51 
 
 
324 aa  130  4.0000000000000003e-29  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0156181  normal  0.0141251 
 
 
-
 
NC_009664  Krad_4401  binding-protein-dependent transport systems inner membrane component  31.42 
 
 
316 aa  130  4.0000000000000003e-29  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal 
 
 
-
 
NC_011369  Rleg2_0257  binding-protein-dependent transport systems inner membrane component  31.37 
 
 
291 aa  129  5.0000000000000004e-29  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.958787  normal 
 
 
-
 
NC_009485  BBta_3226  putative sugar ABC transporter, permease protein  32.5 
 
 
310 aa  129  5.0000000000000004e-29  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.0290776  normal  0.498538 
 
 
-
 
NC_009485  BBta_7824  putative ABC transporter permease protein  31.43 
 
 
295 aa  129  7.000000000000001e-29  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_004311  BRA0305  sugar ABC transporter, permease protein  29.27 
 
 
325 aa  128  1.0000000000000001e-28  Brucella suis 1330  Bacteria  normal  0.0474821  n/a   
 
 
-
 
NC_013595  Sros_3494  binding-protein-dependent transport systems inner membrane component  32.91 
 
 
311 aa  128  1.0000000000000001e-28  Streptosporangium roseum DSM 43021  Bacteria  normal  0.716912  normal  0.704951 
 
 
-
 
NC_010003  Pmob_0028  binding-protein-dependent transport systems inner membrane component  32.91 
 
 
300 aa  127  2.0000000000000002e-28  Petrotoga mobilis SJ95  Bacteria  unclonable  0.0000000378352  n/a   
 
 
-
 
NC_009485  BBta_1755  ABC transporter permease  36.41 
 
 
312 aa  127  2.0000000000000002e-28  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.576454  normal  0.392142 
 
 
-
 
NC_013526  Tter_2052  binding-protein-dependent transport systems inner membrane component  30.93 
 
 
291 aa  127  2.0000000000000002e-28  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009504  BOV_A0280  sugar ABC transporter, permease protein  29.27 
 
 
325 aa  127  2.0000000000000002e-28  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_012852  Rleg_6157  binding-protein-dependent transport systems inner membrane component  30.11 
 
 
300 aa  127  3e-28  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  decreased coverage  0.0000377109 
 
 
-
 
NC_008541  Arth_3142  binding-protein-dependent transport systems inner membrane component  33.57 
 
 
325 aa  126  4.0000000000000003e-28  Arthrobacter sp. FB24  Bacteria  normal  0.406302  n/a   
 
 
-
 
NC_011371  Rleg2_6573  binding-protein-dependent transport systems inner membrane component  30.11 
 
 
300 aa  126  5e-28  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  hitchhiker  0.00258358  normal  0.837912 
 
 
-
 
NC_009486  Tpet_0645  binding-protein-dependent transport systems inner membrane component  29.6 
 
 
309 aa  126  5e-28  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000282921  n/a   
 
 
-
 
NC_011886  Achl_3270  binding-protein-dependent transport systems inner membrane component  33.94 
 
 
321 aa  125  7e-28  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_012669  Bcav_2817  binding-protein-dependent transport systems inner membrane component  31.98 
 
 
310 aa  125  8.000000000000001e-28  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.822068  normal 
 
 
-
 
NC_014158  Tpau_1637  binding-protein-dependent transport systems inner membrane component  30.24 
 
 
303 aa  125  9e-28  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.0695484  n/a   
 
 
-
 
NC_011899  Hore_20510  binding-protein-dependent transport systems inner membrane component  30.2 
 
 
290 aa  125  1e-27  Halothermothrix orenii H 168  Bacteria  normal  0.0790749  n/a   
 
 
-
 
NC_014151  Cfla_1127  binding-protein-dependent transport systems inner membrane component  29.2 
 
 
328 aa  124  1e-27  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.190953  hitchhiker  0.00155627 
 
 
-
 
NC_013131  Caci_2109  binding-protein-dependent transport systems inner membrane component  29.49 
 
 
312 aa  125  1e-27  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.376983 
 
 
-
 
NC_011899  Hore_20620  binding-protein-dependent transport systems inner membrane component  27.51 
 
 
299 aa  124  1e-27  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_009620  Smed_3590  binding-protein-dependent transport systems inner membrane component  27.99 
 
 
301 aa  125  1e-27  Sinorhizobium medicae WSM419  Bacteria  normal  0.657903  normal 
 
 
-
 
NC_013131  Caci_3596  binding-protein-dependent transport systems inner membrane component  31.71 
 
 
325 aa  124  1e-27  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.295531  normal 
 
 
-
 
NC_012848  Rleg_4941  binding-protein-dependent transport systems inner membrane component  31.18 
 
 
309 aa  124  2e-27  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_007604  Synpcc7942_0949  permease protein of sugar ABC transporter  34.16 
 
 
292 aa  124  2e-27  Synechococcus elongatus PCC 7942  Bacteria  normal  0.688345  normal 
 
 
-
 
NC_012912  Dd1591_3241  binding-protein-dependent transport systems inner membrane component  32.24 
 
 
290 aa  124  2e-27  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_13130  binding-protein-dependent transport systems inner membrane component  29.29 
 
 
293 aa  124  2e-27  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_010627  Bphy_7450  binding-protein-dependent transport systems inner membrane component  30.61 
 
 
316 aa  124  2e-27  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010625  Bphy_6370  binding-protein-dependent transport systems inner membrane component  29.61 
 
 
318 aa  124  3e-27  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_007802  Jann_1389  binding-protein-dependent transport systems inner membrane component  30.14 
 
 
300 aa  123  3e-27  Jannaschia sp. CCS1  Bacteria  normal  0.0114019  normal  0.0892858 
 
 
-
 
NC_010483  TRQ2_0670  binding-protein-dependent transport systems inner membrane component  29.96 
 
 
294 aa  124  3e-27  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_1819  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
293 aa  123  3e-27  Thermosipho melanesiensis BI429  Bacteria  normal  0.215175  n/a   
 
 
-
 
NC_009664  Krad_0386  binding-protein-dependent transport systems inner membrane component  31.45 
 
 
304 aa  123  3e-27  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.610758  normal  0.0357706 
 
 
-
 
NC_012669  Bcav_0016  binding-protein-dependent transport systems inner membrane component  29.39 
 
 
311 aa  123  4e-27  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.17058  normal 
 
 
-
 
NC_013172  Bfae_29330  permease component of ABC-type sugar transporter  28.87 
 
 
321 aa  123  5e-27  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_4634  binding-protein-dependent transport systems inner membrane component  30.88 
 
 
292 aa  122  6e-27  Nocardioides sp. JS614  Bacteria  normal  0.219562  n/a   
 
 
-
 
NC_013739  Cwoe_3982  binding-protein-dependent transport systems inner membrane component  30.26 
 
 
316 aa  122  7e-27  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_009675  Anae109_1696  binding-protein-dependent transport systems inner membrane component  37.34 
 
 
291 aa  122  7e-27  Anaeromyxobacter sp. Fw109-5  Bacteria  hitchhiker  0.00180742  normal 
 
 
-
 
NC_013131  Caci_2784  binding-protein-dependent transport systems inner membrane component  30.3 
 
 
306 aa  122  8e-27  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.390449  normal 
 
 
-
 
NC_013526  Tter_2208  binding-protein-dependent transport systems inner membrane component  31.43 
 
 
306 aa  122  9e-27  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.739705  n/a   
 
 
-
 
NC_011899  Hore_00790  binding-protein-dependent transport systems inner membrane component  28.94 
 
 
262 aa  121  9.999999999999999e-27  Halothermothrix orenii H 168  Bacteria  normal  0.772214  n/a   
 
 
-
 
NC_013411  GYMC61_2730  binding-protein-dependent transport systems inner membrane component  31.2 
 
 
300 aa  121  9.999999999999999e-27  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013235  Namu_0185  binding-protein-dependent transport systems inner membrane component  31.99 
 
 
315 aa  121  9.999999999999999e-27  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
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