55 homologs were found in PanDaTox collection
for query gene VC0395_0662 on replicon NC_009456
Organism: Vibrio cholerae O395



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009456  VC0395_0662  hydroxymethylglutaryl-coenzyme A reductase  100 
 
 
420 aa  862    Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_011313  VSAL_II0253  putative 3-hydroxy-3-methylglutaryl coenzyme a reductase  70.38 
 
 
419 aa  594  1e-168  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.0262386  n/a   
 
 
-
 
NC_009784  VIBHAR_05704  3-hydroxy-3-methylglutaryl CoA reductase  66.35 
 
 
420 aa  561  1.0000000000000001e-159  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_013457  VEA_000087  hydroxymethylglutaryl-CoA reductase  69.19 
 
 
420 aa  558  1e-158  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_1947  hydroxymethylglutaryl-coenzyme A reductase  48.63 
 
 
424 aa  370  1e-101  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_009635  Maeo_0718  3-hydroxy-3-methylglutaryl coenzyme A reductase  45.8 
 
 
418 aa  306  5.0000000000000004e-82  Methanococcus aeolicus Nankai-3  Archaea  normal  n/a   
 
 
-
 
NC_009975  MmarC6_0860  3-hydroxy-3-methylglutaryl coenzyme A reductase  44.06 
 
 
408 aa  294  2e-78  Methanococcus maripaludis C6  Archaea  normal  0.187348  n/a   
 
 
-
 
NC_009637  MmarC7_1086  3-hydroxy-3-methylglutaryl coenzyme A reductase  43.8 
 
 
408 aa  293  3e-78  Methanococcus maripaludis C7  Archaea  normal  normal 
 
 
-
 
NC_009135  MmarC5_1589  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.88 
 
 
408 aa  293  5e-78  Methanococcus maripaludis C5  Archaea  normal  0.346816  n/a   
 
 
-
 
NC_009634  Mevan_1099  3-hydroxy-3-methylglutaryl coenzyme A reductase  41.97 
 
 
411 aa  288  1e-76  Methanococcus vannielii SB  Archaea  normal  n/a   
 
 
-
 
NC_008228  Patl_0427  hydroxymethylglutaryl-CoA reductase (NADPH)  42.57 
 
 
395 aa  283  3.0000000000000004e-75  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.601953  n/a   
 
 
-
 
NC_010525  Tneu_1359  3-hydroxy-3-methylglutaryl coenzyme A reductase  45.56 
 
 
395 aa  282  7.000000000000001e-75  Thermoproteus neutrophilus V24Sta  Archaea  normal  normal 
 
 
-
 
CP001800  Ssol_1610  3-hydroxy-3-methylglutaryl Coenzyme A reductase  43.02 
 
 
409 aa  275  9e-73  Sulfolobus solfataricus 98/2  Archaea  normal  n/a   
 
 
-
 
NC_011138  MADE_03398  Hydroxymethylglutaryl-coenzyme A reductase  42.4 
 
 
396 aa  275  1.0000000000000001e-72  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007955  Mbur_1098  3-hydroxy-3-methylglutaryl-coenzyme A reductase  42.65 
 
 
414 aa  273  3e-72  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_013158  Huta_0276  3-hydroxy-3-methylglutaryl Coenzyme A reductase  44 
 
 
403 aa  269  5.9999999999999995e-71  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_011832  Mpal_2647  3-hydroxy-3-methylglutaryl Coenzyme A reductase  42.71 
 
 
407 aa  261  1e-68  Methanosphaerula palustris E1-9c  Archaea  normal  0.259986  normal  0.338347 
 
 
-
 
NC_009376  Pars_0796  3-hydroxy-3-methylglutaryl coenzyme A reductase  47.85 
 
 
398 aa  261  2e-68  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  normal 
 
 
-
 
NC_007355  Mbar_A1972  hydroxymethylglutaryl-CoA reductase (NADPH)  42.72 
 
 
418 aa  260  3e-68  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_013202  Hmuk_1499  3-hydroxy-3-methylglutaryl Coenzyme A reductase  46.57 
 
 
403 aa  260  3e-68  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.398419  normal 
 
 
-
 
NC_007796  Mhun_3004  3-hydroxy-3-methylglutaryl coenzyme A reductase  44.29 
 
 
401 aa  260  3e-68  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_009073  Pcal_1085  3-hydroxy-3-methylglutaryl-coenzyme A reductase  47.56 
 
 
399 aa  259  5.0000000000000005e-68  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal 
 
 
-
 
NC_013743  Htur_0537  3-hydroxy-3-methylglutaryl Coenzyme A reductase  42.71 
 
 
408 aa  259  7e-68  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_008701  Pisl_0814  3-hydroxy-3-methylglutaryl coenzyme A reductase  46.13 
 
 
399 aa  256  4e-67  Pyrobaculum islandicum DSM 4184  Archaea  normal  hitchhiker  0.00207544 
 
 
-
 
NC_009954  Cmaq_0412  3-hydroxy-3-methylglutaryl coenzyme A reductase  42.21 
 
 
410 aa  256  4e-67  Caldivirga maquilingensis IC-167  Archaea  normal  normal 
 
 
-
 
NC_009712  Mboo_0137  3-hydroxy-3-methylglutaryl coenzyme A reductase  43.63 
 
 
426 aa  253  5.000000000000001e-66  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal 
 
 
-
 
NC_009440  Msed_1649  3-hydroxy-3-methylglutaryl-coenzyme A reductase  43.71 
 
 
410 aa  252  1e-65  Metallosphaera sedula DSM 5348  Archaea  normal  0.982475  normal 
 
 
-
 
NC_009051  Memar_2365  3-hydroxy-3-methylglutaryl coenzyme A reductase  44.48 
 
 
402 aa  246  6.999999999999999e-64  Methanoculleus marisnigri JR1  Archaea  normal  n/a   
 
 
-
 
NC_008942  Mlab_1655  3-hydroxy-3-methylglutaryl-coenzyme A reductase  42.12 
 
 
404 aa  244  1.9999999999999999e-63  Methanocorpusculum labreanum Z  Archaea  normal  hitchhiker  0.0000342006 
 
 
-
 
NC_011138  MADE_03508  Hydroxymethylglutaryl-coenzyme A reductase  38.9 
 
 
514 aa  242  1e-62  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_013922  Nmag_2929  3-hydroxy-3-methylglutaryl Coenzyme A reductase  41.88 
 
 
410 aa  242  1e-62  Natrialba magadii ATCC 43099  Archaea  normal  0.342818  n/a   
 
 
-
 
NC_012029  Hlac_2019  3-hydroxy-3-methylglutaryl Coenzyme A reductase  44.19 
 
 
407 aa  227  4e-58  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  normal  0.439309 
 
 
-
 
NC_010117  COXBURSA331_A2174  hydroxymethylglutaryl-coenzyme A reductase  36.76 
 
 
395 aa  213  3.9999999999999995e-54  Coxiella burnetii RSA 331  Bacteria  normal  0.0352988  n/a   
 
 
-
 
NC_011697  PHATRDRAFT_16870  predicted protein  40.43 
 
 
367 aa  206  5e-52  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  n/a   
 
 
-
 
NC_006691  CNF04830  hydroxymethylglutaryl-CoA reductase (NADPH), putative  38.18 
 
 
1283 aa  203  4e-51  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  n/a   
 
 
-
 
BN001302  ANIA_03817  hypothetical protein similar to HMG-CoA reductase (Eurofung)  35.55 
 
 
1125 aa  196  8.000000000000001e-49  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal 
 
 
-
 
NC_009046  PICST_72872  3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)  35.61 
 
 
1047 aa  195  1e-48  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  normal 
 
 
-
 
NC_009727  CBUD_0151  3-hydroxy-3-methylglutaryl-coenzyme A reductase  33.24 
 
 
364 aa  178  2e-43  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  n/a   
 
 
-
 
BN001307  ANIA_01593  conserved hypothetical protein  36.81 
 
 
416 aa  175  9.999999999999999e-43  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal 
 
 
-
 
NC_007520  Tcr_1717  hydroxymethylglutaryl-CoA reductase (NADPH)  35.19 
 
 
352 aa  173  3.9999999999999995e-42  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0723  hydroxymethylglutaryl-CoA reductase (NADPH)  34.8 
 
 
355 aa  164  3e-39  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.000000000015079  n/a   
 
 
-
 
NC_009727  CBUD_0622  3-hydroxy-3-methylglutaryl-coenzyme A reductase  34.8 
 
 
357 aa  164  4.0000000000000004e-39  Coxiella burnetii Dugway 5J108-111  Bacteria  hitchhiker  0.000221084  n/a   
 
 
-
 
NC_008530  LGAS_1373  hydroxymethylglutaryl-CoA reductase  26.18 
 
 
429 aa  65.5  0.000000002  Lactobacillus gasseri ATCC 33323  Bacteria  normal  hitchhiker  0.0000000000375721 
 
 
-
 
NC_009523  RoseRS_0431  hydroxymethylglutaryl-CoA reductase, degradative  24.93 
 
 
456 aa  57  0.0000006  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.316381 
 
 
-
 
NC_010002  Daci_0287  hydroxymethylglutaryl-CoA reductase, degradative  27.08 
 
 
429 aa  55.5  0.000002  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_008528  OEOE_1799  3-hydroxy-3-methylglutaryl-coenzyme A reductase  25.42 
 
 
363 aa  55.5  0.000002  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_0981  hydroxymethylglutaryl-CoA reductase, degradative  24.93 
 
 
444 aa  54.7  0.000003  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_3073  hydroxymethylglutaryl-CoA reductase, degradative  25.99 
 
 
428 aa  52  0.00002  Pseudomonas putida F1  Bacteria  normal  0.272086  normal 
 
 
-
 
NC_006369  lpl2030  hypothetical protein  22.75 
 
 
432 aa  51.6  0.00002  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_006368  lpp2035  hypothetical protein  22.25 
 
 
432 aa  51.2  0.00003  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_013926  Aboo_1461  hydroxymethylglutaryl-CoA reductase, degradative  22.42 
 
 
420 aa  48.5  0.0002  Aciduliprofundum boonei T469  Archaea  normal  0.478544  n/a   
 
 
-
 
NC_011831  Cagg_1141  hydroxymethylglutaryl-CoA reductase, degradative  33.7 
 
 
440 aa  47  0.0006  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.00353445 
 
 
-
 
NC_013515  Smon_1290  hydroxymethylglutaryl-CoA reductase, degradative  19.62 
 
 
406 aa  46.2  0.001  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_008543  Bcen2424_3505  hydroxymethylglutaryl-CoA reductase, degradative  23.7 
 
 
428 aa  45.4  0.002  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_4013  hydroxymethylglutaryl-CoA reductase, degradative  23.7 
 
 
428 aa  45.1  0.003  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.316182 
 
 
-
 
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